{"id":"https://openalex.org/W1624860716","doi":null,"title":"Concentraciones de homociste\u00edna plasm\u00e1tica en embarazadas y su relaci\u00f3n con el desarrollo de preeclampsia. Efecto de la administraci\u00f3n prenatal de \u00e1cido f\u00f3lico.","display_name":"Concentraciones de homociste\u00edna plasm\u00e1tica en embarazadas y su relaci\u00f3n con el desarrollo de preeclampsia. Efecto de la administraci\u00f3n prenatal de \u00e1cido f\u00f3lico.","publication_year":2005,"publication_date":"2005-06-01","ids":{"openalex":"https://openalex.org/W1624860716","mag":"1624860716"},"language":"es","primary_location":{"id":"pmh:oai:redalyc.org:372937660009","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=372937660009","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Investigaci\u00f3n Cl\u00ednica (Rep\u00fablica Bolivariana de Venezuela) Num.2 Vol.46","raw_type":"art\u00edculo cient\u00edfico"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Marisol Fern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203303854","display_name":"Universidad de Los Andes","ror":"https://ror.org/02h1b1x27","country_code":"VE","type":"education","lineage":["https://openalex.org/I203303854"]}],"countries":["VE"],"is_corresponding":false,"raw_author_name":"Marisol Fern\u00e1ndez","raw_affiliation_strings":["ULA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ULA","institution_ids":["https://openalex.org/I203303854"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gerardo Blanco\u2010Fern\u00e1ndez","orcid":"https://orcid.org/0000-0003-4845-5306","observed_orcids":["https://orcid.org/0000-0003-4845-5306"]},"institutions":[{"id":"https://openalex.org/I203303854","display_name":"Universidad de Los Andes","ror":"https://ror.org/02h1b1x27","country_code":"VE","type":"education","lineage":["https://openalex.org/I203303854"]}],"countries":["VE"],"is_corresponding":false,"raw_author_name":"Gerardo Blanco\u2010Fern\u00e1ndez","raw_affiliation_strings":["ULA"],"raw_orcid":"https://orcid.org/0000-0003-4845-5306","affiliations":[{"raw_affiliation_string":"ULA","institution_ids":["https://openalex.org/I203303854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067915046","display_name":"Mar\u00eda Diez\u2010Ewald","orcid":"https://orcid.org/0000-0002-7161-5307","observed_orcids":["https://orcid.org/0000-0002-7161-5307"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u00eda Diez\u2010Ewald","raw_affiliation_strings":["ULA, Maracaibo, Venezuela"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ULA, Maracaibo, Venezuela","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054758629","display_name":"Enrique Torres","orcid":"https://orcid.org/0000-0001-8531-7696","observed_orcids":["https://orcid.org/0000-0001-8531-7696","https://orcid.org/0000-0003-3885-8013","https://orcid.org/0009-0008-9867-3524"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Enrique Torres","raw_affiliation_strings":["ULA, Maracaibo, Venezuela"],"raw_orcid":"https://orcid.org/0000-0001-8531-7696","affiliations":[{"raw_affiliation_string":"ULA, Maracaibo, Venezuela","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053223189","display_name":"Gilberto Vizca\u00edno","orcid":"https://orcid.org/0000-0003-2785-1879","observed_orcids":["https://orcid.org/0000-0003-2785-1879"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gilberto Vizca\u00edno","raw_affiliation_strings":["ULA, Maracaibo, Venezuela"],"raw_orcid":"https://orcid.org/0000-0003-2785-1879","affiliations":[{"raw_affiliation_string":"ULA, Maracaibo, Venezuela","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nelson Fern\u00e1ndez","orcid":"https://orcid.org/0000-0002-6703-2803","observed_orcids":["https://orcid.org/0000-0002-6703-2803"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nelson Fern\u00e1ndez","raw_affiliation_strings":["ULA, Maracaibo, Venezuela"],"raw_orcid":"https://orcid.org/0000-0002-6703-2803","affiliations":[{"raw_affiliation_string":"ULA, Maracaibo, Venezuela","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040826230","display_name":"Janeth Narv\u00e1ez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I203303854","display_name":"Universidad de Los Andes","ror":"https://ror.org/02h1b1x27","country_code":"VE","type":"education","lineage":["https://openalex.org/I203303854"]}],"countries":["VE"],"is_corresponding":false,"raw_author_name":"Janeth Narv\u00e1ez","raw_affiliation_strings":["ULA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ULA","institution_ids":["https://openalex.org/I203303854"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059173837","display_name":"Melvis Arteaga-Vizca\u00edno","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Melvis Arteaga-Vizca\u00edno","raw_affiliation_strings":["ULA, Maracaibo, Venezuela"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ULA, Maracaibo, Venezuela","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":"2","first_page":"179","last_page":"186"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10499","display_name":"Folate and B Vitamins Research","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/homocysteine","display_name":"homocysteine","score":0.8640000224113464},{"id":"https://openalex.org/keywords/hyperhomocysteinemia","display_name":"hyperhomocysteinemia","score":0.890999972820282},{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/eclampsia","display_name":"eclampsia","score":0.9750000238418579},{"id":"https://openalex.org/keywords/folinic-acid-supplementation","display_name":"folinic acid supplementation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.5870000123977661},{"id":"https://openalex.org/keywords/preeclampsia-prevention","display_name":"preeclampsia prevention","score":0.8259999752044678},{"id":"https://openalex.org/keywords/low-income-women","display_name":"low-income women","score":0.7200000286102295},{"id":"https://openalex.org/keywords/first-and-second-trimester","display_name":"first and second trimester","score":0.7170000076293945},{"id":"https://openalex.org/keywords/maternal-serum-folate","display_name":"maternal serum folate","score":0.6100000143051147},{"id":"https://openalex.org/keywords/citrated-plasma","display_name":"citrated plasma","score":0.39800000190734863}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5822233557701111},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3985280394554138}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:redalyc.org:372937660009","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=372937660009","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Investigaci\u00f3n Cl\u00ednica (Rep\u00fablica Bolivariana de Venezuela) Num.2 Vol.46","raw_type":"art\u00edculo cient\u00edfico"},{"id":"mag:1624860716","doi":null,"is_oa":false,"landing_page_url":"https://biblat.unam.mx/es/revista/investigacion-clinica/articulo/concentraciones-de-homocisteina-plasmatica-en-embarazadas-y-su-relacion-con-el-desarrollo-de-preeclampsia-efecto-de-la-administracion-prenatal-de-acido-folico","pdf_url":null,"source":{"id":"https://openalex.org/S4210214429","display_name":"Investigaci\u00f3n Cl\u00ednica","issn_l":"2477-9393","issn":["2477-9393","0535-5133"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1","poland-20","russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Investigaci\u00f3n Cl\u00ednica","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1550947052","https://openalex.org/W1968611348","https://openalex.org/W1986241406","https://openalex.org/W1990376420","https://openalex.org/W1995781460","https://openalex.org/W2015517071","https://openalex.org/W2025961381","https://openalex.org/W2026754030","https://openalex.org/W2049869709","https://openalex.org/W2061921166","https://openalex.org/W2082022423","https://openalex.org/W2089162288","https://openalex.org/W2090474126","https://openalex.org/W2091901611","https://openalex.org/W2098587302","https://openalex.org/W2111359369","https://openalex.org/W2115166939","https://openalex.org/W2155870343","https://openalex.org/W2162407733","https://openalex.org/W2167950412","https://openalex.org/W2419348263"],"related_works":["https://openalex.org/W2997979989","https://openalex.org/W6926538764","https://openalex.org/W2072207709","https://openalex.org/W2185708163","https://openalex.org/W1968942030","https://openalex.org/W4232638102","https://openalex.org/W4300028564","https://openalex.org/W1986612191","https://openalex.org/W7048698372","https://openalex.org/W2054687628"],"abstract_inverted_index":{"\"El":[0],"aumento":[1,18],"de":[2,8,16,31,36,40,57,68,75,94,97,100,112,115,121,130,142,155,166,170,202,209,223,225,229,242,248,266,280,291],"la":[3,14,25,34,55,66,85,98,119,128,221,246,272,278,289,294],"homociste\u00edna":[4,41,143,167,243,267],"en":[5,24,43,65,88,103,144,175,178,187,293],"el":[6,44,52,89,148,179,214],"plasma":[7,145],"las":[9,38,140,154,176,188,230,240,251,257,264],"embarazadas":[10,74,177],"que":[11,54,79,195,258,263,284],"desarrollan":[12],"preeclampsia/eclampsia,":[13],"raz\u00f3n":[15],"este":[17,285],"y":[19,46,51,64,125,153,182,256,283],"su":[20],"posible":[21],"papel":[22],"etiopatog\u00e9nico":[23],"toxemia":[26],"del":[27,49,158,189,274],"embarazo":[28,50,254,275],"son":[29],"objeto":[30],"controversia.":[32],"Con":[33],"finalidad":[35],"conocer":[37],"concentraciones":[39,141,241,265],"plasm\u00e1tica,":[42,268],"primer":[45,90,180],"segundo":[47,92,190],"trimestres":[48,93],"efecto":[53],"administraci\u00f3n":[56,279],"\u00e1cido":[58,116,156,204,281],"f\u00f3lico":[59,117,157,282],"pudiera":[60],"ejercer":[61],"sobre":[62],"ellas":[63],"prevenci\u00f3n":[67],"preeclampsia,":[69],"se":[70,108,138,198,219,235],"estudiaron":[71],"96":[72],"mujeres":[73,252],"bajos":[76],"recursos":[77],"econ\u00f3micos,":[78],"acudieron":[80],"por":[81],"primera":[82],"vez":[83],"a":[84,105,127],"consulta":[86],"prenatal":[87],"o":[91],"gestaci\u00f3n.":[95],"Despu\u00e9s":[96],"extracci\u00f3n":[99,129],"sangre":[101,131],"venosa":[102],"ayunas,":[104],"cada":[106,132,136],"paciente":[107],"le":[109],"entregaron":[110],"comprimidos":[111],"1":[113],"mg":[114],"con":[118,213,253,271,277],"instrucci\u00f3n":[120],"tomar":[122],"uno":[123],"diario":[124],"someterse":[126],"tres":[133],"meses.":[134],"En":[135],"muestra":[137],"determinaron":[139],"citratado,":[146],"mediante":[147,160],"sistema":[149],"IMX":[150],"(Abbott":[151],"Laboratories)":[152],"suero,":[159],"radioinmunoan\u00e1lisis":[161],"(Diagnostic":[162],"Products).":[163],"La":[164],"concentraci\u00f3n":[165],"basal":[168],"fue":[169],"4,0":[171],"\u00b1":[172,184],"2,1":[173,185],"\u00b5mol/L":[174,186],"trimestre":[181],"4,8":[183],"(p":[191],"=":[192],"N.S.),":[193],"sin":[194,217],"estos":[196],"valores":[197],"modificaran":[199],"significativamente":[200],"despu\u00e9s":[201],"recibir":[203],"f\u00f3lico.":[205],"Un":[206],"alto":[207],"n\u00famero":[208],"pacientes":[210],"no":[211,269,287],"cumpli\u00f3":[212],"estudio":[215],"trimestral,":[216],"embargo":[218],"conoci\u00f3":[220],"evoluci\u00f3n":[222],"65":[224],"ellas,":[226],"10":[227],"(15,4%)":[228],"cuales":[231],"desarrollaron":[232,259],"preeclampsia.":[233,260],"No":[234],"encontraron":[236],"diferencias":[237],"significativas":[238],"entre":[239,245,250],"ni":[244,276],"frecuencia":[247],"hiperhomocisteinemia":[249],"normal":[255],"Se":[261],"concluye":[262],"variaron":[270],"edad":[273],"\u00faltimo":[286],"influenci\u00f3":[288],"aparici\u00f3n":[290],"preeclampsia":[292],"poblaci\u00f3n":[295],"estudiada.\"":[296]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}