{"id":"https://openalex.org/W161399633","doi":null,"title":"Diesel exhaust and wood smoke : mechanisms, inflammation and intervention","display_name":"Diesel exhaust and wood smoke : mechanisms, inflammation and intervention","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W161399633","mag":"161399633"},"language":"en","primary_location":{"id":"pmh:oai:DiVA.org:umu-88614","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88614","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88614","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033863474","display_name":"Ala Muala","orcid":"https://orcid.org/0009-0009-2345-7584","observed_orcids":["https://orcid.org/0009-0009-2345-7584"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ala Muala","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-2345-7584","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5033863474"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10190","display_name":"Air Quality and Health Impacts","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11002","display_name":"Indoor Air Quality and Microbial Exposure","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diesel-exhaust","display_name":"diesel exhaust","score":0.843999981880188},{"id":"https://openalex.org/keywords/wood-smoke","display_name":"wood smoke","score":0.9959999918937683},{"id":"https://openalex.org/keywords/particulate-matter","display_name":"particulate matter","score":0.9520000219345093},{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.5889999866485596},{"id":"https://openalex.org/keywords/lung-deposition","display_name":"lung deposition","score":0.6890000104904175},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.9459999799728394},{"id":"https://openalex.org/keywords/airway-inflammation","display_name":"airway inflammation","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8930000066757202},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.7179999947547913},{"id":"https://openalex.org/keywords/myeloperoxidase","display_name":"myeloperoxidase","score":0.8220000267028809},{"id":"https://openalex.org/keywords/mmp-9","display_name":"MMP-9","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cabin-air-filters","display_name":"cabin air filters","score":0.8619999885559082},{"id":"https://openalex.org/keywords/charcoal-filters","display_name":"charcoal filters","score":0.7720000147819519},{"id":"https://openalex.org/keywords/nitric-oxide-bioavailability","display_name":"nitric oxide bioavailability","score":0.9539999961853027},{"id":"https://openalex.org/keywords/nitric-oxide-synthase-inhibition","display_name":"nitric oxide synthase inhibition","score":0.9200000166893005},{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.7279999852180481},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.8109999895095825},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.6949999928474426},{"id":"https://openalex.org/keywords/cardiovascular-effects","display_name":"cardiovascular effects","score":0.5509999990463257}],"concepts":[{"id":"https://openalex.org/C58874564","wikidata":"https://www.wikidata.org/wiki/Q130768","display_name":"Smoke","level":2,"score":0.7054121494293213},{"id":"https://openalex.org/C3432839","wikidata":"https://www.wikidata.org/wiki/Q336041","display_name":"Diesel exhaust","level":3,"score":0.53400719165802},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.4383643865585327},{"id":"https://openalex.org/C138171918","wikidata":"https://www.wikidata.org/wiki/Q38423","display_name":"Diesel fuel","level":2,"score":0.4342890977859497},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.3857164978981018},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.3445948362350464},{"id":"https://openalex.org/C548081761","wikidata":"https://www.wikidata.org/wiki/Q180388","display_name":"Waste management","level":1,"score":0.3302229046821594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2082536220550537},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.19077670574188232},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:DiVA.org:umu-88614","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88614","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:161399633","doi":null,"is_oa":false,"landing_page_url":"https://umu.diva-portal.org/smash/record.jsf?pid=diva2:716558","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:DiVA.org:umu-88614","doi":null,"is_oa":true,"landing_page_url":"http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-88614","pdf_url":null,"source":{"id":"https://openalex.org/S4306401559","display_name":"KTH Publication Database DiVA (KTH Royal Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I86987016","host_organization_name":"KTH Royal Institute of Technology","host_organization_lineage":["https://openalex.org/I86987016"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":109,"referenced_works":["https://openalex.org/W96804355","https://openalex.org/W198917345","https://openalex.org/W1555489744","https://openalex.org/W1580210576","https://openalex.org/W1798158436","https://openalex.org/W1897626150","https://openalex.org/W1967900132","https://openalex.org/W1972063938","https://openalex.org/W1974850809","https://openalex.org/W1976327152","https://openalex.org/W1985754956","https://openalex.org/W1986113982","https://openalex.org/W1988601441","https://openalex.org/W1996172059","https://openalex.org/W1998727175","https://openalex.org/W1998826231","https://openalex.org/W1998938457","https://openalex.org/W2005135073","https://openalex.org/W2009080406","https://openalex.org/W2011879443","https://openalex.org/W2012394874","https://openalex.org/W2021470166","https://openalex.org/W2024908526","https://openalex.org/W2026038000","https://openalex.org/W2026121051","https://openalex.org/W2027580901","https://openalex.org/W2029241241","https://openalex.org/W2029592641","https://openalex.org/W2031194554","https://openalex.org/W2038343834","https://openalex.org/W2039044077","https://openalex.org/W2039638453","https://openalex.org/W2040327996","https://openalex.org/W2045044513","https://openalex.org/W2045557277","https://openalex.org/W2048254190","https://openalex.org/W2048512830","https://openalex.org/W2049325520","https://openalex.org/W2054205781","https://openalex.org/W2057619950","https://openalex.org/W2057970249","https://openalex.org/W2061997886","https://openalex.org/W2063945670","https://openalex.org/W2066088673","https://openalex.org/W2066600186","https://openalex.org/W2072110237","https://openalex.org/W2072187367","https://openalex.org/W2073473383","https://openalex.org/W2074008288","https://openalex.org/W2076577278","https://openalex.org/W2077318536","https://openalex.org/W2077701973","https://openalex.org/W2081689933","https://openalex.org/W2086443418","https://openalex.org/W2090423385","https://openalex.org/W2094513568","https://openalex.org/W2094947929","https://openalex.org/W2096001387","https://openalex.org/W2096625392","https://openalex.org/W2097941784","https://openalex.org/W2098915731","https://openalex.org/W2100067518","https://openalex.org/W2104761649","https://openalex.org/W2105120637","https://openalex.org/W2107115075","https://openalex.org/W2109400845","https://openalex.org/W2109559748","https://openalex.org/W2109996123","https://openalex.org/W2110052313","https://openalex.org/W2111398073","https://openalex.org/W2112787621","https://openalex.org/W2119073032","https://openalex.org/W2120016654","https://openalex.org/W2120351270","https://openalex.org/W2121369371","https://openalex.org/W2121605783","https://openalex.org/W2121659530","https://openalex.org/W2124009903","https://openalex.org/W2124713635","https://openalex.org/W2125065061","https://openalex.org/W2125539459","https://openalex.org/W2125577634","https://openalex.org/W2128401506","https://openalex.org/W2128643205","https://openalex.org/W2129100479","https://openalex.org/W2136410036","https://openalex.org/W2138211885","https://openalex.org/W2138998720","https://openalex.org/W2140787730","https://openalex.org/W2141018820","https://openalex.org/W2143967568","https://openalex.org/W2144873766","https://openalex.org/W2150751323","https://openalex.org/W2151386419","https://openalex.org/W2153802091","https://openalex.org/W2155477484","https://openalex.org/W2156304629","https://openalex.org/W2157878090","https://openalex.org/W2157901178","https://openalex.org/W2159431141","https://openalex.org/W2162083455","https://openalex.org/W2162487812","https://openalex.org/W2164256953","https://openalex.org/W2166381556","https://openalex.org/W2166616596","https://openalex.org/W2166980789","https://openalex.org/W2313326603","https://openalex.org/W2416262024","https://openalex.org/W2419604885"],"related_works":["https://openalex.org/W2974822644","https://openalex.org/W2167249616","https://openalex.org/W643537044","https://openalex.org/W4403700500","https://openalex.org/W59433807","https://openalex.org/W7095572321","https://openalex.org/W311275792","https://openalex.org/W2171222014","https://openalex.org/W2104798736","https://openalex.org/W2107107504"],"abstract_inverted_index":{"Background":[0],"Particulate":[1],"matter":[2],"(PM)":[3],"air":[4,28,131,159,181,281,446],"pollution":[5,29],"is":[6],"associated":[7],"with":[8,206,257,283,319,352,450],"increased":[9,342,366],"respiratory":[10],"and":[11,14,20,30,54,56,106,123,141,160,182,203,213,232,236,248,270,294,315,345,359,459],"cardiovascular":[12],"morbidity":[13],"mortality.":[15],"Diesel":[16],"engine":[17,473],"exhaust":[18],"(DE)":[19],"wood":[21,96,121,228,244],"combustion":[22,101,388],"are":[23],"major":[24],"contributors":[25],"to":[26,40,57,64,120,157,179,261,313,335,390,405,455,471],"ambient":[27],"adverse":[31,81,475],"health":[32,426,476],"effects.":[33,427,477],"The":[34,220,401,428],"aim":[35],"of":[36,44,75,84,95,148,194,208,226,243,422,466],"this":[37],"thesis":[38],"was":[39,102,114,187,230,288,453],"investigate":[41],"the":[42,48,59,73,76,80,145,149,192,227,253,262,298,330,365,374,379,406],"fate":[43],"inhaled":[45],"combustion-derived":[46],"PM,":[47],"subsequent":[49,425,460],"effects":[50,83],"on":[51],"pulmonary":[52],"inflammation":[53,113],"symptomatology":[55],"explore":[58],"potential":[60,147],"for":[61,139,234,373,415,424],"particle":[62,448],"filters":[63,133],"improve":[65],"public":[66],"health.":[67],"Additionally,":[68],"it":[69,469],"aimed":[70],"at":[71],"increasing":[72],"understanding":[74],"pathophysiological":[77],"mechanisms":[78],"underlying":[79],"vascular":[82,357],"PM":[85,222,417],"inhalation":[86],"in":[87,104,116,191,252,291,297,322,329,355,378],"man.":[88],"Methods":[89],"In":[90,109,126,172,264],"study":[91,110,127,173],"I,":[92],"lung":[93],"deposition":[94,224,395],"smoke-derived":[97],"particulates":[98],"from":[99,386,398,410],"incomplete":[100,387],"determined":[103],"healthy":[105,117,175,235],"COPD":[107,237],"subjects.":[108],"II,":[111],"airway":[112,394,402],"assessed":[115,188],"subjects":[118,153,176,238],"exposed":[119,156,178],"smoke":[122,229,245,384],"filtered":[124,150,158,167,180,316],"air.":[125],"III,":[128],"vehicle":[129,444],"cabin":[130,280,445],"inlet":[132,447],"were":[134,154,177],"evaluated":[135],"regarding":[136],"filtering":[137],"capacity":[138],"DE":[140,166,314,349,433,457],"whether":[142],"they":[143],"affected":[144],"toxicological":[146],"PM.":[151],"Healthy":[152],"then":[155],"unfiltered":[161],"DE,":[162],"as":[163,165],"well":[164],"through":[168],"two":[169],"selected":[170],"filters.":[171],"IV,":[174],"DE.":[183],"Nitric":[184],"oxide":[185],"bioavailability":[186,377],"by":[189,439],"plethysmography":[190],"presence":[193],"an":[195,284,320,327,353],"NO":[196,305,332,339,368,376,441],"clamp":[197],"(NO":[198],"synthase":[199,306,340],"inhibitor":[200],"NG-monomethyl":[201],"locally":[202],"systemically":[204],"administered)":[205],"measurements":[207],"arterial":[209,343],"stiffness,":[210],"cardiac":[211,361],"output":[212],"blood":[214,346],"pressure":[215,347],"(BP).":[216],"Results":[217],"Study":[218,240,276,302],"I:":[219],"total":[221],"number":[223],"fraction":[225],"0.32":[231],"0.35":[233],"respectively.":[239],"II:":[241],"Inhalation":[242],"caused":[246,308],"CD3+":[247],"mast":[249],"cell":[250,259],"infiltration":[251],"bronchial":[254,265],"submucosa":[255],"along":[256,318,351],"CD8+":[258],"recruitment":[260],"epithelium.":[263],"wash,":[266],"inflammatory":[267,403],"cells,":[268],"myeloperoxidase":[269],"matrix":[271],"metalloproteinase":[272],"9":[273],"levels":[274],"decreased.":[275],"III:":[277],"An":[278],"efficient":[279],"filter":[282,449],"active":[285,451],"charcoal":[286,452],"component":[287],"most":[289],"favourable":[290],"in-vitro":[292],"tests":[293],"reduced":[295,360,375,440],"symptoms":[296],"human":[299],"exposure":[300,312,350,434,458],"study.":[301],"IV:":[303],"Local":[304],"inhibition":[307,341],"similar":[309],"vasoconstriction":[310],"after":[311,348,432],"air,":[317],"increase":[321,328,354],"plasma":[323],"nitrate":[324],"concentrations,":[325],"suggesting":[326],"basal":[331,367],"release":[333,369],"due":[334],"oxidative":[336],"stress.":[337],"Systemic":[338],"stiffness":[344],"systemic":[356],"resistance":[358],"output,":[362],"implying":[363],"that":[364],"could":[370],"not":[371],"compensate":[372],"conduit":[380],"vessels.":[381],"Conclusion":[382],"Wood":[383],"particles":[385,397,408],"tend":[389],"have":[391,412],"a":[392],"greater":[393],"than":[396],"better":[399],"combustion.":[400],"responses":[404],"former":[407],"differ":[409],"what":[411],"been":[413],"shown":[414,431],"other":[416],"pollutants,":[418],"which":[419],"may":[420,435,463],"be":[421,437,465],"importance":[423],"vasomotor":[429],"dysfunction":[430],"largely":[436],"explained":[438],"bioavailability.":[442],"A":[443],"effective":[454],"reduce":[456],"symptoms.":[461],"This":[462],"conceptually":[464],"benefit":[467],"when":[468],"comes":[470],"decreasing":[472],"exhaust-related":[474]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
