{"id":"https://openalex.org/W1609745591","doi":null,"title":"Methodological and Clinical Studies on Insulin Resistance in Childhood","display_name":"Methodological and Clinical Studies on Insulin Resistance in Childhood","publication_year":2011,"publication_date":"2011-03-29","ids":{"openalex":"https://openalex.org/W1609745591","mag":"1609745591"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26916496","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Methodological_and_clinical_studies_on_insulin_resistance_in_childhood/26916496","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/40507","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089058057","display_name":"Sophia M R\u00f6ssner","orcid":"https://orcid.org/0000-0001-7717-5616","observed_orcids":["https://orcid.org/0000-0001-7717-5616"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"S R\u00f6ssner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7717-5616","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5089058057"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.019300000742077827,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.01510000042617321,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9990000128746033},{"id":"https://openalex.org/keywords/childhood-obesity","display_name":"childhood obesity","score":0.7549999952316284},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.871999979019165},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.6299999952316284},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9380000233650208},{"id":"https://openalex.org/keywords/homa-ir","display_name":"HOMA-IR","score":0.8429999947547913},{"id":"https://openalex.org/keywords/quantitative-insulin-sensitivity-check-index","display_name":"QUICKI","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fasting-insulin","display_name":"fasting insulin","score":0.7390000224113464},{"id":"https://openalex.org/keywords/c-peptide-kinetics","display_name":"C-peptide kinetics","score":0.8420000076293945},{"id":"https://openalex.org/keywords/first-phase-insulin-secretion","display_name":"first-phase insulin secretion","score":0.7670000195503235},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.9430000185966492},{"id":"https://openalex.org/keywords/intravenous-glucose-tolerance-test","display_name":"intravenous glucose tolerance test","score":0.7639999985694885},{"id":"https://openalex.org/keywords/puberty","display_name":"puberty","score":0.5109999775886536},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7760000228881836},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.3659999966621399},{"id":"https://openalex.org/keywords/adiponectin","display_name":"adiponectin","score":0.7020000219345093}],"concepts":[{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.7577136754989624},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.5264029502868652},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.42406466603279114},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.3806595802307129},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29494208097457886},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2022300362586975},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26916496","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Methodological_and_clinical_studies_on_insulin_resistance_in_childhood/26916496","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/40507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/40507","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1609745591","doi":null,"is_oa":false,"landing_page_url":"http://openarchive.ki.se/xmlui/handle/10616/40507","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/40507","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/40507","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":198,"referenced_works":["https://openalex.org/W51950288","https://openalex.org/W314630959","https://openalex.org/W1273018688","https://openalex.org/W1482685153","https://openalex.org/W1493922188","https://openalex.org/W1495740709","https://openalex.org/W1549751084","https://openalex.org/W1553733060","https://openalex.org/W1675830194","https://openalex.org/W1688381890","https://openalex.org/W1759025867","https://openalex.org/W1769768807","https://openalex.org/W1838131144","https://openalex.org/W1907575477","https://openalex.org/W1907902304","https://openalex.org/W1965561480","https://openalex.org/W1966509583","https://openalex.org/W1967257827","https://openalex.org/W1967883258","https://openalex.org/W1969615014","https://openalex.org/W1971273629","https://openalex.org/W1972590376","https://openalex.org/W1972733074","https://openalex.org/W1973255904","https://openalex.org/W1973842058","https://openalex.org/W1977797609","https://openalex.org/W1981933686","https://openalex.org/W1986018654","https://openalex.org/W1986436191","https://openalex.org/W1986833595","https://openalex.org/W1987243476","https://openalex.org/W1988870963","https://openalex.org/W1989578736","https://openalex.org/W1991026143","https://openalex.org/W1991795789","https://openalex.org/W1993812967","https://openalex.org/W1994895769","https://openalex.org/W1994931740","https://openalex.org/W1995063589","https://openalex.org/W1995288989","https://openalex.org/W1998965274","https://openalex.org/W1999971397","https://openalex.org/W2002537454","https://openalex.org/W2004540975","https://openalex.org/W2005933532","https://openalex.org/W2006940598","https://openalex.org/W2008131742","https://openalex.org/W2008283534","https://openalex.org/W2010344167","https://openalex.org/W2011210301","https://openalex.org/W2012898950","https://openalex.org/W2014376568","https://openalex.org/W2016717298","https://openalex.org/W2017602160","https://openalex.org/W2018135697","https://openalex.org/W2018378590","https://openalex.org/W2018459966","https://openalex.org/W2022801078","https://openalex.org/W2024286468","https://openalex.org/W2024305859","https://openalex.org/W2026850118","https://openalex.org/W2027670788","https://openalex.org/W2028717709","https://openalex.org/W2030019992","https://openalex.org/W2030455994","https://openalex.org/W2031235345","https://openalex.org/W2031637294","https://openalex.org/W2031840166","https://openalex.org/W2032422942","https://openalex.org/W2035586426","https://openalex.org/W2038018821","https://openalex.org/W2038081709","https://openalex.org/W2038874580","https://openalex.org/W2039669512","https://openalex.org/W2040606975","https://openalex.org/W2042015461","https://openalex.org/W2042637405","https://openalex.org/W2043106623","https://openalex.org/W2044005860","https://openalex.org/W2044660941","https://openalex.org/W2048473455","https://openalex.org/W2049025878","https://openalex.org/W2049113370","https://openalex.org/W2049481764","https://openalex.org/W2052836193","https://openalex.org/W2054135157","https://openalex.org/W2056428314","https://openalex.org/W2056713556","https://openalex.org/W2057709162","https://openalex.org/W2059341564","https://openalex.org/W2059842910","https://openalex.org/W2060431825","https://openalex.org/W2061121182","https://openalex.org/W2063554399","https://openalex.org/W2064351344","https://openalex.org/W2065620282","https://openalex.org/W2067096633","https://openalex.org/W2067262787","https://openalex.org/W2068824840","https://openalex.org/W2069419303","https://openalex.org/W2070099193","https://openalex.org/W2070892520","https://openalex.org/W2072271848","https://openalex.org/W2073655225","https://openalex.org/W2073720428","https://openalex.org/W2077060147","https://openalex.org/W2078156869","https://openalex.org/W2083368201","https://openalex.org/W2085057119","https://openalex.org/W2086434878","https://openalex.org/W2086964476","https://openalex.org/W2087871199","https://openalex.org/W2089119460","https://openalex.org/W2092868590","https://openalex.org/W2094004225","https://openalex.org/W2096773810","https://openalex.org/W2097838137","https://openalex.org/W2099051331","https://openalex.org/W2103240149","https://openalex.org/W2104129218","https://openalex.org/W2105912552","https://openalex.org/W2106015468","https://openalex.org/W2107674876","https://openalex.org/W2107948325","https://openalex.org/W2108462699","https://openalex.org/W2109469605","https://openalex.org/W2111230909","https://openalex.org/W2111435591","https://openalex.org/W2111574921","https://openalex.org/W2111869124","https://openalex.org/W2111953703","https://openalex.org/W2113751056","https://openalex.org/W2113796718","https://openalex.org/W2115177689","https://openalex.org/W2115830695","https://openalex.org/W2116215087","https://openalex.org/W2117584722","https://openalex.org/W2118202935","https://openalex.org/W2119785019","https://openalex.org/W2120035516","https://openalex.org/W2120166232","https://openalex.org/W2120282127","https://openalex.org/W2122660225","https://openalex.org/W2123106337","https://openalex.org/W2123870033","https://openalex.org/W2124620553","https://openalex.org/W2124948826","https://openalex.org/W2126327417","https://openalex.org/W2126545477","https://openalex.org/W2127283734","https://openalex.org/W2129221351","https://openalex.org/W2129316761","https://openalex.org/W2130171861","https://openalex.org/W2130200187","https://openalex.org/W2130850001","https://openalex.org/W2131063873","https://openalex.org/W2132681327","https://openalex.org/W2133137653","https://openalex.org/W2134293572","https://openalex.org/W2138065933","https://openalex.org/W2140409181","https://openalex.org/W2141674942","https://openalex.org/W2142932338","https://openalex.org/W2145265693","https://openalex.org/W2146877877","https://openalex.org/W2152420113","https://openalex.org/W2153747727","https://openalex.org/W2155059543","https://openalex.org/W2155937127","https://openalex.org/W2156595285","https://openalex.org/W2158418727","https://openalex.org/W2159047663","https://openalex.org/W2159080529","https://openalex.org/W2159896083","https://openalex.org/W2160234571","https://openalex.org/W2161071101","https://openalex.org/W2162261303","https://openalex.org/W2162979864","https://openalex.org/W2163339425","https://openalex.org/W2164418602","https://openalex.org/W2164849270","https://openalex.org/W2165256339","https://openalex.org/W2165274499","https://openalex.org/W2165785647","https://openalex.org/W2168581409","https://openalex.org/W2169171744","https://openalex.org/W2170864435","https://openalex.org/W2171440185","https://openalex.org/W2171589158","https://openalex.org/W2172957830","https://openalex.org/W2175942611","https://openalex.org/W2176172321","https://openalex.org/W2246750959","https://openalex.org/W2324841714","https://openalex.org/W2329905745","https://openalex.org/W2413550547","https://openalex.org/W2415055339","https://openalex.org/W2430143578"],"related_works":["https://openalex.org/W317157435","https://openalex.org/W2142932338","https://openalex.org/W2183113706","https://openalex.org/W2069498758","https://openalex.org/W1508068225","https://openalex.org/W2183324459","https://openalex.org/W2316309532","https://openalex.org/W2182171530","https://openalex.org/W2422098310","https://openalex.org/W2320447576"],"abstract_inverted_index":{"Insulin":[0,137,682],"resistance":[1,35,55,81,180,253,421,565],"is":[2,22,52,56,343],"a":[3,57,174,325,353,368,375,389,438,458,469,506,649],"condition":[4],"in":[5,17,41,44,66,77,125,177,181,198,230,254,345,349,357,419,522,526,623,736],"which":[6,92,329,547],"adequate":[7,15],"amounts":[8],"of":[9,33,60,69,108,152,165,190,207,237,278,286,313,361,385,393,407,441,451,468,471,509,531,536,541,546,563,574,603,619,653],"insulin":[10,34,54,80,109,144,179,231,252,300,338,341,420,443,462,503,557,564,567,575,620],"fail":[11],"to":[12,29,94,114,147,352,388,412,486],"give":[13],"an":[14,84,295,497],"response":[16],"target":[18],"tissues.":[19],"This":[20,167,433],"thesis":[21],"based":[23],"on":[24,305,374,426,447,461,596,648],"five":[25],"different":[26,31],"studies,":[27],"aiming":[28],"investigate":[30],"aspects":[32,562],"and":[36,43,64,86,98,128,142,163,184,211,256,270,280,288,315,356,422,430,492,538,554,566,577,583,585,599,626,645,733],"the":[37,61,67,75,115,135,148,153,156,188,199,205,226,235,276,284,359,382,394,401,408,428,448,550,555,681,712],"assessment":[38,111,133,579,622],"methods":[39,220,573,587,618],"thereof":[40],"children":[42,127,255,625],"adults.":[45],"The":[46,130,215,268,494],"rationale":[47],"for":[48,251,283,490,706],"performing":[49],"these":[50,191,219,238],"studies":[51,272],"that":[53,170,209,244],"key":[58],"component":[59],"metabolic":[62,466],"syndrome":[63],"crucial":[65],"development":[68,598],"type":[70],"2":[71],"diabetes.":[72],"Concomitant":[73],"with":[74,155,204,265,275,311,378,445,476,516,740],"increase":[76],"obesity":[78],"worldwide,":[79],"has":[82],"become":[83],"important":[85],"increasingly":[87],"more":[88],"common":[89],"pathological":[90],"condition,":[91],"needs":[93],"be":[95,223,263],"efficiently":[96],"diagnosed":[97],"treated.":[99],"\u2022":[100,193,267,364,454],"In":[101,322,365,559],"Study":[102,194,323,366,455],"I":[103],"we":[104,185],"investigated":[105,582],"proxy":[106],"measures":[107],"sensitivity":[110,463,578,621],"as":[112,247,484],"compared":[113,146,485],"reference":[116],"standard":[117,651],"Frequently":[118,684,713],"Sampled":[119,685,714],"Intravenous":[120,686,715],"Glucose":[121,687,716,731],"Tolerance":[122,688,717],"Test":[123],"(FSIVGTT)":[124],"obese":[126,201,624],"adolescents.":[129,627],"Homeostasis":[131],"model":[132,326,371,395,435],"(HOMA-IR),":[134],"Quantitative":[136],"Sensitivity":[138,149],"Check":[139],"Index":[140],"(QUICKI)":[141],"fasting":[143,171,245],"were":[145,273,543],"index":[150],"(Si)":[151],"FSIVGTT":[154,302],"sample":[157],"stratified":[158],"by":[159,464],"sex,":[160],"puberty":[161],"status":[162],"median":[164,507],"Si.":[166],"study":[168,495],"demonstrated":[169],"indices":[172,246],"have":[173,569,580],"low":[175],"validity":[176],"identifying":[178],"this":[182,591],"group,":[183],"generally":[186],"discourage":[187],"use":[189],"methods.":[192,239],"II":[195],"was":[196,303,327,372,524],"performed":[197,274,304],"same":[200],"pediatric":[202],"population":[203],"aim":[206,277],"showing":[208],"HOMA-IR":[210,644],"QUICKI":[212],"are":[213,417],"interchangeable.":[214],"numerous":[216],"comparisons":[217],"between":[218],"should":[221],"thus":[222],"avoided.":[224],"Also,":[225],"high":[227,405],"physiologic":[228],"fluctuations":[229],"levels":[232,416,530,535,540],"further":[233,594,655],"undermine":[234],"robustness":[236],"Studies":[240],"I-II":[241],"provide":[242,437],"evidence":[243],"simple":[248],"screening":[249],"tools":[250],"adolescents":[257],"should,":[258],"if":[259],"used":[260],"at":[261,318],"all,":[262],"interpreted":[264],"caution.":[266],"third":[269],"fourth":[271],"developing":[279],"validating":[281],"models":[282],"kinetics":[285],"C-peptide":[287,314,333,678],"Nonesterified":[289,707],"fatty":[290],"acids":[291],"(NEFAs)":[292],"respectively":[293],"during":[294,742],"intravenous":[296],"glucose":[297,390,424],"challenge.":[298,391],"An":[299,512],"modified":[301],"healthy":[306,487],"normal":[307],"weight":[308],"young":[309,737],"adults,":[310],"sampling":[312,320],"NEFAs":[316],"included":[317],"all":[319,545],"points.":[321],"III":[324],"developed":[328],"assesses":[330],"first":[331],"phase":[332],"secretion,":[334],"indirectly":[335],"also":[336],"estimating":[337,442],"secretion.":[339],"Assessing":[340],"secretion":[342,568,576],"useful":[344],"understanding":[346],"diabetes":[347,452,597],"development,":[348],"assessing":[350],"progression":[351],"diabetic":[354],"state":[355],"monitoring":[358],"effect":[360],"therapeutic":[362],"regimens.":[363],"IV":[367],"novel":[369],"NEFA":[370,386,415,434],"validated":[373],"subject":[376],"level,":[377],"curves":[379],"well":[380],"fitting":[381],"diverse":[383],"range":[384],"responses":[387],"Validation":[392],"using":[396],"static":[397,413],"parameters":[398,411],"derived":[399],"from":[400],"dynamic":[402,410],"counterparts":[403],"showed":[404],"correlation":[406],"model\u2019s":[409],"parameters.":[414],"elevated":[418],"affect":[423],"homeostasis":[425],"both":[427],"short":[429],"long":[431],"term.":[432],"may":[436,548],"complementary":[439],"way":[440],"sensitivity,":[444,504],"focus":[446],"lipotoxic":[449],"aspect":[450],"development.":[453],"V":[456],"provides":[457],"clinical":[459],"perspective":[460],"examining":[465],"features":[467],"cohort":[470],"long-term":[472],"cancer":[473,527],"survivors":[474],"treated":[475,739],"stem":[477],"cell":[478],"transplantation":[479],"including":[480],"total":[481],"body":[482,514,552,734],"irradiation,":[483],"controls":[488,523],"matched":[489],"age":[491],"sex.":[493],"shows":[496],"intact":[498],"\u03b2-cell":[499],"function,":[500],"but":[501],"decreased":[502],"after":[505],"follow-up":[508],"18":[510],"years.":[511],"adverse":[513,551],"composition":[515,553,735],"higher":[517,534],"proportion":[518],"fat":[519],"mass":[520],"than":[521],"seen":[525],"survivors.":[528],"Lower":[529],"growth":[532],"hormone,":[533],"leptin":[537],"lower":[539],"adiponectin":[542],"found,":[544],"explain":[549],"reduced":[556],"sensitivity.":[558],"summary,":[560],"several":[561],"been":[570,581],"studied.":[571],"Existing":[572],"implemented,":[584],"new":[586],"described.":[588],"We":[589],"hope":[590],"will":[592],"contribute":[593],"knowledge":[595],"treatment":[600],"strategies.":[601],"List":[602],"scientific":[604],"papers":[605],"I.":[606],"Rossner":[607,634,663,692,723],"SM,":[608,612,635,664,693,724],"Neovius":[609,636,698],"M,":[610,637,699],"Montgomery":[611],"Marcus":[613,640],"C,":[614,641],"Norgren":[615,642,673,694,725],"S.":[616,643,674],"Alternative":[617],"Diabetes":[628],"Care.":[629],"2008":[630],"Apr;31(4):802-4.":[631],"https://doi.org/10.2337/dc07-1655":[632],"II.":[633],"Mattsson":[638],"A,":[639],"QUICKI:":[646],"decide":[647],"general":[650],"instead":[652],"making":[654],"comparisons.":[656],"Acta":[657],"Paediatr.":[658],"2010":[659,747],"Nov;99(11):1735-40.":[660],"https://doi.org/10.1111/j.1651-2227.2010.01911.x":[661],"III.":[662],"Boston":[665,702],"R,":[666],"Carlsson":[667,696],"K,":[668,697],"Ward":[669],"GM,":[670],"Gustafsson":[671,700,729],"J,":[672,701,728],"Modeling":[675],"First":[676],"Phase":[677],"Secretion":[679],"During":[680,711],"Modified":[683],"Test.":[689,718],"[Submitted]":[690,719],"IV.":[691],"S,":[695,726],"R.":[703],"A":[704],"Model":[705],"Fatty":[708],"Acid":[709],"Kinetics":[710],"V.":[720],"Frisk":[721],"P,":[722],"Arvidson":[727],"J.":[730],"metabolism":[732],"adults":[738],"TBI":[741],"childhood.":[743],"Bone":[744],"Marrow":[745],"Transplant.":[746],"Dec":[748],"13.":[749],"https://doi.org/10.1038/bmt.2010.307":[750]},"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}