{"id":"https://openalex.org/W1607825394","doi":null,"title":"Agudizaci\u00f3n grave del asma","display_name":"Agudizaci\u00f3n grave del asma","publication_year":2003,"publication_date":"2003-05-08","ids":{"openalex":"https://openalex.org/W1607825394","mag":"1607825394"},"language":"es","primary_location":{"id":"mag:1607825394","doi":null,"is_oa":false,"landing_page_url":"https://www.analesdepediatria.org/es-pdf-13046476","pdf_url":null,"source":{"id":"https://openalex.org/S136590224","display_name":"Anales de Pediatr\u00eda","issn_l":"1695-4033","issn":["1695-4033","1695-9531"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Anales de Pediatr\u00eda","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062757576","display_name":"Federico Martin\u00f3n\u2010Torres","orcid":"https://orcid.org/0000-0002-9023-581X","observed_orcids":["https://orcid.org/0000-0002-9023-581X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Federico Martin\u00f3n\u2010Torres","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016858510","display_name":"Manuel Fern\u00e1ndez Sanmart\u00edn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Fern\u00e1ndez Sanmart\u00edn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087870686","display_name":"E Saavedra Chaves","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Saavedra Chaves","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105470669","display_name":"Mercedes Granero Asencio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Granero Asencio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103622076","display_name":"J.M. Martin\u00f3n S\u00e1nchez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096311","display_name":"Complejo Hospitalario Universitario de Santiago","ror":"https://ror.org/00mpdg388","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210096311"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J.M. Martin\u00f3n S\u00e1nchez","raw_affiliation_strings":["Servicio de Cr\u00edticos, Intermedios y Urgencias Pedi\u00e1tricas. Hospital Cl\u00ednico Universitario de Santiago de Compostela. Espa\u00f1a"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio de Cr\u00edticos, Intermedios y Urgencias Pedi\u00e1tricas. Hospital Cl\u00ednico Universitario de Santiago de Compostela. Espa\u00f1a","institution_ids":["https://openalex.org/I4210096311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":1.4075,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.81518121,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"58","issue":null,"first_page":"1","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-severe-asthma","display_name":"status asthmaticus","score":0.8579999804496765},{"id":"https://openalex.org/keywords/severe-asthma-exacerbation","display_name":"severe asthma exacerbation","score":0.8579999804496765},{"id":"https://openalex.org/keywords/childhood-asthma","display_name":"childhood asthma","score":0.8560000061988831},{"id":"https://openalex.org/keywords/ipratropium-bromide","display_name":"ipratropium bromide","score":0.968999981880188},{"id":"https://openalex.org/keywords/magnesium-sulfate","display_name":"magnesium sulfate","score":0.6010000109672546},{"id":"https://openalex.org/keywords/non-invasive-ventilation","display_name":"non-invasive ventilation","score":0.6959999799728394},{"id":"https://openalex.org/keywords/endotracheal-intubation","display_name":"endotracheal intubation","score":0.7319999933242798},{"id":"https://openalex.org/keywords/leukotriene-modifiers","display_name":"leukotriene modifiers","score":0.7269999980926514},{"id":"https://openalex.org/keywords/phosphodiesterase-inhibitors","display_name":"phosphodiesterase inhibitors","score":0.9850000143051147},{"id":"https://openalex.org/keywords/heliox","display_name":"heliox","score":0.7870000004768372},{"id":"https://openalex.org/keywords/treatment-algorithm","display_name":"treatment algorithm","score":0.382999986410141}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.7256300449371338},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3658493459224701},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.3494165241718292}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1607825394","doi":null,"is_oa":false,"landing_page_url":"https://www.analesdepediatria.org/es-pdf-13046476","pdf_url":null,"source":{"id":"https://openalex.org/S136590224","display_name":"Anales de Pediatr\u00eda","issn_l":"1695-4033","issn":["1695-4033","1695-9531"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","oarl","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Anales de Pediatr\u00eda","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":138,"referenced_works":["https://openalex.org/W42056970","https://openalex.org/W60626692","https://openalex.org/W117285554","https://openalex.org/W118040161","https://openalex.org/W121799997","https://openalex.org/W140638440","https://openalex.org/W164805863","https://openalex.org/W174360810","https://openalex.org/W1498546445","https://openalex.org/W1601042312","https://openalex.org/W1666116380","https://openalex.org/W1744558393","https://openalex.org/W1934138862","https://openalex.org/W1963518443","https://openalex.org/W1964474257","https://openalex.org/W1966402203","https://openalex.org/W1967892805","https://openalex.org/W1968665040","https://openalex.org/W1970547200","https://openalex.org/W1972962057","https://openalex.org/W1973972675","https://openalex.org/W1974918991","https://openalex.org/W1975596133","https://openalex.org/W1977986666","https://openalex.org/W1980730576","https://openalex.org/W1984234076","https://openalex.org/W1984334137","https://openalex.org/W1984488833","https://openalex.org/W1985723578","https://openalex.org/W1985790812","https://openalex.org/W1986462973","https://openalex.org/W1986489453","https://openalex.org/W1986808738","https://openalex.org/W1989817630","https://openalex.org/W1989847221","https://openalex.org/W1993800650","https://openalex.org/W1996982788","https://openalex.org/W1998794045","https://openalex.org/W2002089374","https://openalex.org/W2002497517","https://openalex.org/W2004015495","https://openalex.org/W2004055147","https://openalex.org/W2004559058","https://openalex.org/W2005497039","https://openalex.org/W2008660872","https://openalex.org/W2009908181","https://openalex.org/W2010421380","https://openalex.org/W2013179556","https://openalex.org/W2017805361","https://openalex.org/W2018283681","https://openalex.org/W2018677234","https://openalex.org/W2020408216","https://openalex.org/W2020653299","https://openalex.org/W2023284062","https://openalex.org/W2023715929","https://openalex.org/W2025029128","https://openalex.org/W2026934822","https://openalex.org/W2026975680","https://openalex.org/W2028038133","https://openalex.org/W2028742025","https://openalex.org/W2030070356","https://openalex.org/W2030647820","https://openalex.org/W2031889988","https://openalex.org/W2032205757","https://openalex.org/W2035207228","https://openalex.org/W2035376550","https://openalex.org/W2036788491","https://openalex.org/W2040519486","https://openalex.org/W2042027156","https://openalex.org/W2043400069","https://openalex.org/W2045354989","https://openalex.org/W2047668646","https://openalex.org/W2047903212","https://openalex.org/W2049452778","https://openalex.org/W2050433888","https://openalex.org/W2050720836","https://openalex.org/W2050959239","https://openalex.org/W2052475539","https://openalex.org/W2055094574","https://openalex.org/W2058686437","https://openalex.org/W2059640347","https://openalex.org/W2061233391","https://openalex.org/W2064686200","https://openalex.org/W2066350149","https://openalex.org/W2067240253","https://openalex.org/W2069523694","https://openalex.org/W2073817403","https://openalex.org/W2074346570","https://openalex.org/W2074647124","https://openalex.org/W2074743533","https://openalex.org/W2080832419","https://openalex.org/W2081180353","https://openalex.org/W2081189862","https://openalex.org/W2083036937","https://openalex.org/W2087283741","https://openalex.org/W2089952340","https://openalex.org/W2091959059","https://openalex.org/W2092327213","https://openalex.org/W2096002594","https://openalex.org/W2096426156","https://openalex.org/W2099542571","https://openalex.org/W2103268644","https://openalex.org/W2103548755","https://openalex.org/W2106972463","https://openalex.org/W2107311678","https://openalex.org/W2109373124","https://openalex.org/W2110826983","https://openalex.org/W2116731818","https://openalex.org/W2119200928","https://openalex.org/W2120255743","https://openalex.org/W2128921798","https://openalex.org/W2129186256","https://openalex.org/W2129204630","https://openalex.org/W2131733306","https://openalex.org/W2132629966","https://openalex.org/W2137908269","https://openalex.org/W2138543395","https://openalex.org/W2149524195","https://openalex.org/W2153633382","https://openalex.org/W2154984195","https://openalex.org/W2162101498","https://openalex.org/W2163778909","https://openalex.org/W2165246623","https://openalex.org/W2165714979","https://openalex.org/W2170374219","https://openalex.org/W2170613763","https://openalex.org/W2320848488","https://openalex.org/W2325607557","https://openalex.org/W2331306740","https://openalex.org/W2403443972","https://openalex.org/W2408713869","https://openalex.org/W2410337657","https://openalex.org/W2410878002","https://openalex.org/W2417778834","https://openalex.org/W2465810352","https://openalex.org/W2467377082","https://openalex.org/W2986158377","https://openalex.org/W4239303575"],"related_works":["https://openalex.org/W7046847035","https://openalex.org/W7105700822","https://openalex.org/W1967892805","https://openalex.org/W2984643271","https://openalex.org/W4406046431","https://openalex.org/W4399081687","https://openalex.org/W2915149664","https://openalex.org/W2996159977","https://openalex.org/W4409726380","https://openalex.org/W4238011778"],"abstract_inverted_index":{"El":[0],"presente":[1],"trabajo":[2],"utiliza":[3],"la":[4,7,11,142,171],"metodologia":[5],"de":[6,23,36,49,59,90,104,120,125,173],"medicina":[8],"basada":[9],"en":[10,41,64,101,166],"evidencia":[12],"para:":[13],"a)":[14],"revisar":[15],"las":[16,24,126],"opciones":[17],"terapeuticas":[18],"disponibles":[19],"para":[20,131,162],"el":[21,57,98,116,163],"tratamiento":[22,31,68],"exacerbaciones":[25],"asmaticas":[26],"agudas":[27],"severas":[28],"refractarias":[29],"al":[30,67],"convencional":[32,69],"maximo":[33,70],"(agudizacion":[34],"grave":[35],"asma":[37],"o":[38,86,110],"estatus":[39,164],"asmatico)":[40],"ninos,":[42,167],"y":[43,74,176,180],"b)":[44],"proporcionar":[45],"un":[46,80,88],"algoritmo":[47],"orientativo":[48],"actuacion":[50],"practica.":[51],"Despues":[52],"del":[53],"analisis,":[54],"concluimos":[55],"que":[56,96,168],"bromuro":[58],"ipratropio":[60],"deberia":[61],"ser":[62],"anadido":[63],"primer":[65],"lugar":[66],"(oxigeno,":[71],"b2-agonistas":[72],"nebulizado":[73],"corticoides":[75],"sistemicos).":[76],"Posteriormente,":[77],"podria":[78],"realizarse":[79],"ensayo":[81],"terapeutico":[82],"con":[83,87],"sulfato":[84],"magnesico":[85],"bolo":[89],"salbutamol":[91],"intravenoso.":[92],"No":[93],"existen":[94],"evidencias":[95],"sustenten":[97],"uso":[99],"rutinario":[100],"este":[102],"contexto":[103],"furosemida,":[105],"lidocaina,":[106],"glucagon,":[107],"antibioticos,":[108],"mucoliticos":[109],"fisioterapia":[111],"respiratoria.":[112],"Otros":[113],"tratamientos":[114,150,161],"como":[115],"heliox,":[117],"los":[118,123,149],"modificadores":[119],"leucotrienos":[121],"intravenosos,":[122],"inhibidores":[124],"fosfodiesterasas,":[127],"requieren":[128],"nuevos":[129,160],"estudios":[130],"determinar":[132],"su":[133,181],"verdadera":[134],"utilidad.":[135],"La":[136],"ventilacion":[137,177],"mecanica":[138,178],"no":[139],"invasiva":[140],"constituye":[141],"opcion":[143],"terapeutica":[144],"mas":[145],"valiosa":[146],"cuando":[147],"todos":[148],"farmacologicos":[151],"han":[152],"fracasado.":[153],"En":[154],"cualquier":[155],"caso,":[156],"continuan":[157],"siendo":[158],"necesarios":[159],"asmatico":[165],"permitan":[169],"prevenir":[170],"necesidad":[172],"intubacion":[174],"endotraqueal":[175],"invasiva,":[179],"morbilidad":[182],"asociada.":[183]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
