{"id":"https://openalex.org/W1605712367","doi":"https://doi.org/10.36104/amc.2011.1449","title":"S\u00edndrome de anticuerpos antifosfol\u00edpidos asociado a la presencia de inhibidor adquirido del factor IX en una paciente sin hemofilia","display_name":"S\u00edndrome de anticuerpos antifosfol\u00edpidos asociado a la presencia de inhibidor adquirido del factor IX en una paciente sin hemofilia","publication_year":2019,"publication_date":"2019-08-04","ids":{"openalex":"https://openalex.org/W1605712367","doi":"https://doi.org/10.36104/amc.2011.1449","mag":"1605712367"},"language":"es","primary_location":{"id":"doi:10.36104/amc.2011.1449","doi":"https://doi.org/10.36104/amc.2011.1449","is_oa":true,"landing_page_url":"https://doi.org/10.36104/amc.2011.1449","pdf_url":"http://www.actamedicacolombiana.com/ojs/index.php/actamed/article/download/1449/425","source":{"id":"https://openalex.org/S4210194006","display_name":"Acta M\u00e9dica Colombiana","issn_l":"0120-2448","issn":["0120-2448","2248-6054"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["publindex-c","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Colombiana","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","datacite"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://www.actamedicacolombiana.com/ojs/index.php/actamed/article/download/1449/425","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110971403","display_name":"Philippe Chalem","orcid":"https://orcid.org/0000-0002-4588-5311","observed_orcids":["https://orcid.org/0000-0002-4588-5311"]},"institutions":[{"id":"https://openalex.org/I108484188","display_name":"Fundaci\u00f3n Universitaria San Mart\u00edn","ror":"https://ror.org/010ps5r85","country_code":"CO","type":"education","lineage":["https://openalex.org/I108484188"]},{"id":"https://openalex.org/I90803817","display_name":"Universidad del Rosario","ror":"https://ror.org/0108mwc04","country_code":"CO","type":"education","lineage":["https://openalex.org/I90803817"]}],"countries":["CO"],"is_corresponding":true,"raw_author_name":"Philippe Chalem","raw_affiliation_strings":["Universidad del Rosario (Bogot\u00e1, Colombia)","Fundaci\u00f3n Universitaria San Mart\u00edn, Bogot\u00e1 D. C., Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad del Rosario (Bogot\u00e1, Colombia)","institution_ids":["https://openalex.org/I90803817"]},{"raw_affiliation_string":"Fundaci\u00f3n Universitaria San Mart\u00edn, Bogot\u00e1 D. C., Colombia","institution_ids":["https://openalex.org/I108484188"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5110971403"],"corresponding_institution_ids":["https://openalex.org/I108484188","https://openalex.org/I90803817"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00023244,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"36","issue":"4","first_page":"196","last_page":"199"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9926999807357788,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antiphospholipid-syndrome","display_name":"antiphospholipid syndrome","score":0.9919999837875366},{"id":"https://openalex.org/keywords/hemophilia-b","display_name":"hemophilia B","score":0.7599999904632568},{"id":"https://openalex.org/keywords/hemophilia-a","display_name":"hemophilia A","score":0.9710000157356262},{"id":"https://openalex.org/keywords/recurrent-deep-vein-thrombosis","display_name":"recurrent deep vein thrombosis","score":0.7519999742507935},{"id":"https://openalex.org/keywords/antiphospholipid-antibodies","display_name":"antiphospholipid antibodies","score":0.871999979019165},{"id":"https://openalex.org/keywords/anticardiolipin-antibodies","display_name":"anticardiolipin antibodies","score":0.9190000295639038},{"id":"https://openalex.org/keywords/lupus-anticoagulant","display_name":"lupus anticoagulant","score":0.847000002861023},{"id":"https://openalex.org/keywords/bleeding-manifestations","display_name":"bleeding manifestations","score":0.4429999887943268},{"id":"https://openalex.org/keywords/corticosteroid-therapy","display_name":"corticosteroid therapy","score":0.7289999723434448},{"id":"https://openalex.org/keywords/cyclophosphamide","display_name":"cyclophosphamide","score":0.8920000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7530034780502319},{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.5034257769584656},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3802185654640198},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.17175549268722534}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.36104/amc.2011.1449","doi":"https://doi.org/10.36104/amc.2011.1449","is_oa":true,"landing_page_url":"https://doi.org/10.36104/amc.2011.1449","pdf_url":"http://www.actamedicacolombiana.com/ojs/index.php/actamed/article/download/1449/425","source":{"id":"https://openalex.org/S4210194006","display_name":"Acta M\u00e9dica Colombiana","issn_l":"0120-2448","issn":["0120-2448","2248-6054"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["publindex-c","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Colombiana","raw_type":"journal-article"},{"id":"pmh:oai:redalyc.org:163122508006","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=163122508006","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Acta M\u00e9dica Colombiana (Colombia) Num.4 Vol.36","raw_type":"art\u00edculo cient\u00edfico"},{"id":"doi:10.60692/2cj9j-tyt96","doi":"https://doi.org/10.60692/2cj9j-tyt96","is_oa":true,"landing_page_url":"https://doi.org/10.60692/2cj9j-tyt96","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/fcm1j-45v46","doi":"https://doi.org/10.60692/fcm1j-45v46","is_oa":true,"landing_page_url":"https://doi.org/10.60692/fcm1j-45v46","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"mag:1589219443","doi":null,"is_oa":false,"landing_page_url":"http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-24482011000400006","pdf_url":null,"source":{"id":"https://openalex.org/S4210194006","display_name":"Acta M\u00e9dica Colombiana","issn_l":"0120-2448","issn":["0120-2448","2248-6054"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["publindex-c","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta Medica Colombiana","raw_type":null},{"id":"mag:2292232879","doi":null,"is_oa":false,"landing_page_url":"http://actamedicacolombiana.com/anexo/articulos/06-SindromeAnticuerpos-SAF.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"doi:10.36104/amc.2011.1449","doi":"https://doi.org/10.36104/amc.2011.1449","is_oa":true,"landing_page_url":"https://doi.org/10.36104/amc.2011.1449","pdf_url":"http://www.actamedicacolombiana.com/ojs/index.php/actamed/article/download/1449/425","source":{"id":"https://openalex.org/S4210194006","display_name":"Acta M\u00e9dica Colombiana","issn_l":"0120-2448","issn":["0120-2448","2248-6054"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["publindex-c","scielo"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Acta M\u00e9dica Colombiana","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1605712367.pdf","grobid_xml":"https://content.openalex.org/works/W1605712367.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1963634373","https://openalex.org/W1990749117","https://openalex.org/W1991508429","https://openalex.org/W1996014782","https://openalex.org/W2027467473","https://openalex.org/W2027977330","https://openalex.org/W2048647774","https://openalex.org/W2071010808","https://openalex.org/W2085662278","https://openalex.org/W2087266162","https://openalex.org/W2094904744","https://openalex.org/W2122646363","https://openalex.org/W2135433033","https://openalex.org/W2143947466","https://openalex.org/W2160198109","https://openalex.org/W2165139684"],"related_works":["https://openalex.org/W2292232879","https://openalex.org/W1589219443","https://openalex.org/W4309446899","https://openalex.org/W7206973463","https://openalex.org/W4403554474","https://openalex.org/W2043955064","https://openalex.org/W7001381769","https://openalex.org/W4412993217","https://openalex.org/W7000832000","https://openalex.org/W1901408544"],"abstract_inverted_index":{"Se":[0],"presenta":[1,46],"el":[2,41,52],"caso":[3],"de":[4,7,10,14,16,23,33,43,54,59,65,73,81,83,90],"una":[5,63],"paciente":[6],"23":[8],"a\u00f1os":[9],"edad,":[11],"con":[12,19,71],"diagn\u00f3stico":[13],"s\u00edndrome":[15],"anticuerpos":[17,37],"antifosfol\u00edpidos,":[18],"un":[20],"cuadro":[21],"t\u00edpico":[22],"trombosis":[24],"venosa":[25],"profunda":[26],"recurrente":[27],"y":[28,36,69,92],"p\u00e9rdidas":[29],"fetales,":[30],"en":[31],"presencia":[32],"anticoagulante":[34],"l\u00fapico":[35],"anticardiolipina":[38],"positivos.":[39],"En":[40],"transcurso":[42],"su":[44],"enfermedad":[45],"manifestaciones":[47],"hemorr\u00e1gicas,":[48],"no":[49],"explicadas":[50],"por":[51],"uso":[53,89],"anticoagulantes":[55],"orales.":[56],"Los":[57],"estudios":[58],"hematolog\u00eda":[60],"permitieron":[61],"documentar":[62],"disminuci\u00f3n":[64],"los":[66],"factores":[67,82],"IX":[68],"VIII,":[70],"evidencia":[72],"inhibidor":[74],"espec\u00edfico":[75],"del":[76],"factor":[77],"IX.":[78],"La":[79],"deficiencia":[80],"la":[84],"coagulaci\u00f3n":[85],"mejor\u00f3":[86],"gracias":[87],"al":[88],"esteroides":[91],"ciclofosfamida":[93]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}