{"id":"https://openalex.org/W1604852296","doi":"https://doi.org/10.2527/1997.7561495x","title":"Effect of testosterone on differential muscle growth and on protein and nucleic acid concentrations in muscles of growing lambs.","display_name":"Effect of testosterone on differential muscle growth and on protein and nucleic acid concentrations in muscles of growing lambs.","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W1604852296","doi":"https://doi.org/10.2527/1997.7561495x","mag":"1604852296","pmid":"https://pubmed.ncbi.nlm.nih.gov/9250509"},"language":"en","primary_location":{"id":"doi:10.2527/1997.7561495x","doi":"https://doi.org/10.2527/1997.7561495x","is_oa":false,"landing_page_url":"https://doi.org/10.2527/1997.7561495x","pdf_url":null,"source":{"id":"https://openalex.org/S72684844","display_name":"Journal of Animal Science","issn_l":"0021-8812","issn":["0021-8812","1525-3015","1525-3163","1544-7847"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Animal Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049232174","display_name":"Andrew Arnold","orcid":"https://orcid.org/0000-0002-8821-8527","observed_orcids":["https://orcid.org/0000-0002-8821-8527"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210092791","display_name":"New York State College of Agriculture & Life Sciences","ror":"https://ror.org/00j52pq61","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A M Arnold","raw_affiliation_strings":["Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J M Peralta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210092791","display_name":"New York State College of Agriculture & Life Sciences","ror":"https://ror.org/00j52pq61","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J M Peralta","raw_affiliation_strings":["Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066744932","display_name":"M. L. Thonney","orcid":"https://orcid.org/0000-0003-2713-3084","observed_orcids":["https://orcid.org/0000-0003-2713-3084"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]},{"id":"https://openalex.org/I4210092791","display_name":"New York State College of Agriculture & Life Sciences","ror":"https://ror.org/00j52pq61","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"M L Thonney","raw_affiliation_strings":["Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Science, Cornell University, Ithaca, NY 14853-4801, USA","institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210092791"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5066744932"],"corresponding_institution_ids":["https://openalex.org/I205783295","https://openalex.org/I4210092791"],"apc_list":{"value":4368,"currency":"USD","value_usd":4368},"apc_paid":null,"fwci":1.9832,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.82813048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"75","issue":"6","first_page":"1495","last_page":"1495"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13338","display_name":"Pharmacological Effects and Assays","score":0.7143999934196472,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13338","display_name":"Pharmacological Effects and Assays","score":0.7143999934196472,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.14990000426769257,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10333","display_name":"Meat and Animal Product Quality","score":0.044599998742341995,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.9660000205039978},{"id":"https://openalex.org/keywords/muscle-growth","display_name":"muscle growth","score":0.8980000019073486},{"id":"https://openalex.org/keywords/lambs","display_name":"lambs","score":0.7200000286102295},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.5929999947547913},{"id":"https://openalex.org/keywords/testosterone-implants","display_name":"testosterone implants","score":0.4740000069141388},{"id":"https://openalex.org/keywords/splenius-muscle","display_name":"splenius muscle","score":0.8349999785423279},{"id":"https://openalex.org/keywords/semitendinosus-muscle","display_name":"semitendinosus","score":0.9369999766349792},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.7429999709129333}],"concepts":[{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.7676995396614075},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.6181989312171936},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5043653249740601},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4983677864074707},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.4937652051448822},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.48114025592803955},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47201651334762573},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38445842266082764},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24807298183441162},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16496658325195312},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.061953991651535034}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D009124","descriptor_name":"Muscle Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D009696","descriptor_name":"Nucleic Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013739","descriptor_name":"Testosterone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D024510","descriptor_name":"Muscle Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2527/1997.7561495x","doi":"https://doi.org/10.2527/1997.7561495x","is_oa":false,"landing_page_url":"https://doi.org/10.2527/1997.7561495x","pdf_url":null,"source":{"id":"https://openalex.org/S72684844","display_name":"Journal of Animal Science","issn_l":"0021-8812","issn":["0021-8812","1525-3015","1525-3163","1544-7847"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Animal Science","raw_type":"journal-article"},{"id":"pmid:9250509","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9250509","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of animal science","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.40450000762939453,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W7750287","https://openalex.org/W82215265","https://openalex.org/W83289710","https://openalex.org/W87830391","https://openalex.org/W100891000","https://openalex.org/W132334566","https://openalex.org/W1519541918","https://openalex.org/W1535500489","https://openalex.org/W1906197854","https://openalex.org/W1965154480","https://openalex.org/W1981218555","https://openalex.org/W1982414860","https://openalex.org/W1985312562","https://openalex.org/W1996278640","https://openalex.org/W2014347811","https://openalex.org/W2019823056","https://openalex.org/W2042505776","https://openalex.org/W2058415907","https://openalex.org/W2076308949","https://openalex.org/W2086503195","https://openalex.org/W2111910271","https://openalex.org/W2162702340","https://openalex.org/W2277826552","https://openalex.org/W2328337416","https://openalex.org/W2438082778","https://openalex.org/W2471634115","https://openalex.org/W2540465416"],"related_works":["https://openalex.org/W102172002","https://openalex.org/W1830828757","https://openalex.org/W2086503195","https://openalex.org/W2128555918","https://openalex.org/W2403332392","https://openalex.org/W2189574212","https://openalex.org/W2099690293","https://openalex.org/W4406286069","https://openalex.org/W1994029271","https://openalex.org/W1586515035"],"abstract_inverted_index":{"Growth,":[0],"nucleic":[1],"acid,":[2],"and":[3,16,37,58,68,73,94,101,125,133],"protein":[4,74],"concentrations":[5,75,135],"were":[6,27,62,79,99],"measured":[7],"in":[8,163],"three":[9,87],"muscles":[10,61,78,91],"of":[11,48,65,76,85,92,117,152,159],"20":[12,14,17],"rams,":[13],"wethers,":[15],"wethers":[18,95,118,127,137],"implanted":[19,96,126],"with":[20,97,156],"testosterone.":[21],"Two":[22],"lambs":[23],"from":[24,32],"each":[25],"group":[26],"slaughtered":[28],"at":[29,39],"14-d":[30],"intervals":[31,41],"49":[33],"to":[34,147],"133":[35],"d,":[36,44],"then":[38],"28-d":[40],"until":[42],"217":[43],"for":[45],"a":[46,103,120],"total":[47],"10":[49],"slaughter":[50],"ages.":[51],"Immediately":[52],"after":[53],"slaughter,":[54],"the":[55,86,108,114,149,157],"semitendinosus,":[56],"splenius,":[57],"triceps":[59],"brachii":[60],"removed,":[63],"trimmed":[64],"adhering":[66],"fat,":[67],"weighed.":[69],"The":[70,89],"DNA,":[71],"RNA,":[72],"these":[77],"determined.":[80],"Testosterone":[81],"increased":[82],"combined":[83,109],"weight":[84,111,140],"muscles.":[88,167],"splenius":[90,115,130],"rams":[93],"testosterone":[98],"heavier":[100],"had":[102,119,128],"biphasic":[104],"growth":[105,122,155],"pattern":[106],"as":[107,138],"muscle":[110,116,131,139,154],"increased,":[112],"whereas":[113],"single":[121],"phase.":[123],"Rams":[124],"greater":[129],"DNA":[132],"RNA":[134],"than":[136],"increased.":[141],"This":[142],"model":[143],"could":[144],"be":[145],"used":[146],"study":[148],"gene":[150],"regulation":[151],"testosterone-induced":[153],"possibility":[158],"invoking":[160],"similar":[161],"effects":[162],"more":[164],"economically":[165],"important":[166]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}