{"id":"https://openalex.org/W1600765266","doi":null,"title":"Surgery for Complex Disorders of the Upper Digestive Tract","display_name":"Surgery for Complex Disorders of the Upper Digestive Tract","publication_year":2010,"publication_date":"2010-02-11","ids":{"openalex":"https://openalex.org/W1600765266","mag":"1600765266"},"language":"en","primary_location":{"id":"pmh:oai:dspace.library.uu.nl:1874/40160","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/40160","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://dspace.library.uu.nl/handle/1874/40160","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070456343","display_name":"Edgar J.B. Furn\u00e9e","orcid":"https://orcid.org/0000-0002-3712-3798","observed_orcids":["https://orcid.org/0000-0002-3712-3798"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Edgar J.B. Furn\u00e9e","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-3712-3798","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5070456343"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10671","display_name":"Gastroesophageal reflux and treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antireflux-surgery","display_name":"antireflux surgery","score":0.8190000057220459},{"id":"https://openalex.org/keywords/gastroesophageal-reflux-disease","display_name":"gastroesophageal reflux disease","score":0.9190000295639038},{"id":"https://openalex.org/keywords/laparoscopic-hiatal-hernia-repair","display_name":"laparoscopic hiatal hernia repair","score":0.8360000252723694},{"id":"https://openalex.org/keywords/large-hiatal-hernia","display_name":"large hiatal hernia","score":0.8009999990463257},{"id":"https://openalex.org/keywords/postoperative-dysphagia","display_name":"postoperative dysphagia","score":0.7269999980926514},{"id":"https://openalex.org/keywords/upper-gastrointestinal-tract","display_name":"upper gastrointestinal tract","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9104201793670654},{"id":"https://openalex.org/C2778197217","wikidata":"https://www.wikidata.org/wiki/Q727153","display_name":"Hiatal hernia","level":4,"score":0.7365468144416809},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.7148817777633667},{"id":"https://openalex.org/C43270747","wikidata":"https://www.wikidata.org/wiki/Q898610","display_name":"Reflux","level":3,"score":0.4481724798679352},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.37486758828163147},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09706118702888489}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:dspace.library.uu.nl:1874/40160","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/40160","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},{"id":"pmh:umcu:oai:dspace.library.uu.nl:1874/40160","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/40160","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:uu:oai:dspace.library.uu.nl:1874/40160","doi":null,"is_oa":true,"landing_page_url":"http://dspace.library.uu.nl/handle/1874/40160","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:1600765266","doi":null,"is_oa":false,"landing_page_url":"https://dspace.library.uu.nl/bitstream/1874/40160/1/furnee.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:dspace.library.uu.nl:1874/40160","doi":null,"is_oa":true,"landing_page_url":"https://dspace.library.uu.nl/handle/1874/40160","pdf_url":null,"source":{"id":"https://openalex.org/S4306401649","display_name":"Utrecht University Repository (Utrecht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193662353","host_organization_name":"Utrecht University","host_organization_lineage":["https://openalex.org/I193662353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dissertation"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":193,"referenced_works":["https://openalex.org/W18393817","https://openalex.org/W29563934","https://openalex.org/W50855658","https://openalex.org/W113018998","https://openalex.org/W185809241","https://openalex.org/W226359435","https://openalex.org/W1467623993","https://openalex.org/W1505868566","https://openalex.org/W1506487485","https://openalex.org/W1526009909","https://openalex.org/W1558864742","https://openalex.org/W1561828924","https://openalex.org/W1577077560","https://openalex.org/W1600609211","https://openalex.org/W1690813155","https://openalex.org/W1897718937","https://openalex.org/W1954997772","https://openalex.org/W1966096580","https://openalex.org/W1966987116","https://openalex.org/W1966989612","https://openalex.org/W1967480642","https://openalex.org/W1968149765","https://openalex.org/W1969943010","https://openalex.org/W1971871631","https://openalex.org/W1974036557","https://openalex.org/W1974449221","https://openalex.org/W1976451094","https://openalex.org/W1977095317","https://openalex.org/W1977992861","https://openalex.org/W1979537975","https://openalex.org/W1980678124","https://openalex.org/W1981498440","https://openalex.org/W1982764280","https://openalex.org/W1983134172","https://openalex.org/W1984235970","https://openalex.org/W1987140294","https://openalex.org/W1988071097","https://openalex.org/W1990436341","https://openalex.org/W1991112152","https://openalex.org/W1991289593","https://openalex.org/W1992591395","https://openalex.org/W1992671215","https://openalex.org/W1993538267","https://openalex.org/W1996501711","https://openalex.org/W1997301278","https://openalex.org/W1997353090","https://openalex.org/W1998588410","https://openalex.org/W1999958804","https://openalex.org/W2000074694","https://openalex.org/W2000679668","https://openalex.org/W2002121941","https://openalex.org/W2002436704","https://openalex.org/W2002879879","https://openalex.org/W2003326215","https://openalex.org/W2004902185","https://openalex.org/W2005025007","https://openalex.org/W2005384688","https://openalex.org/W2005444794","https://openalex.org/W2006303084","https://openalex.org/W2006721277","https://openalex.org/W2006794282","https://openalex.org/W2007480227","https://openalex.org/W2009627741","https://openalex.org/W2009740693","https://openalex.org/W2010887537","https://openalex.org/W2010942492","https://openalex.org/W2012339033","https://openalex.org/W2013776047","https://openalex.org/W2015724864","https://openalex.org/W2015726503","https://openalex.org/W2016145656","https://openalex.org/W2016750763","https://openalex.org/W2017578760","https://openalex.org/W2017722345","https://openalex.org/W2018505820","https://openalex.org/W2019814411","https://openalex.org/W2023644441","https://openalex.org/W2024067425","https://openalex.org/W2024227410","https://openalex.org/W2026885273","https://openalex.org/W2028035079","https://openalex.org/W2028939404","https://openalex.org/W2029664479","https://openalex.org/W2030777043","https://openalex.org/W2031470189","https://openalex.org/W2033547573","https://openalex.org/W2036664532","https://openalex.org/W2037377025","https://openalex.org/W2039966124","https://openalex.org/W2041792872","https://openalex.org/W2043869513","https://openalex.org/W2044034087","https://openalex.org/W2045237123","https://openalex.org/W2046147489","https://openalex.org/W2047500606","https://openalex.org/W2050176151","https://openalex.org/W2050276915","https://openalex.org/W2051273341","https://openalex.org/W2051837217","https://openalex.org/W2054659679","https://openalex.org/W2054738182","https://openalex.org/W2056807183","https://openalex.org/W2057337540","https://openalex.org/W2057622711","https://openalex.org/W2058546916","https://openalex.org/W2059555390","https://openalex.org/W2059633004","https://openalex.org/W2060133023","https://openalex.org/W2061242881","https://openalex.org/W2062968365","https://openalex.org/W2063207559","https://openalex.org/W2065635024","https://openalex.org/W2067877526","https://openalex.org/W2069008786","https://openalex.org/W2070211294","https://openalex.org/W2073913054","https://openalex.org/W2074577002","https://openalex.org/W2077051727","https://openalex.org/W2077376527","https://openalex.org/W2077899288","https://openalex.org/W2081821662","https://openalex.org/W2082249655","https://openalex.org/W2084524297","https://openalex.org/W2084770952","https://openalex.org/W2085870635","https://openalex.org/W2086039511","https://openalex.org/W2088362797","https://openalex.org/W2089253770","https://openalex.org/W2090402859","https://openalex.org/W2091000616","https://openalex.org/W2091263988","https://openalex.org/W2091471784","https://openalex.org/W2099999179","https://openalex.org/W2100066666","https://openalex.org/W2102891869","https://openalex.org/W2104297387","https://openalex.org/W2104864149","https://openalex.org/W2105247139","https://openalex.org/W2105462650","https://openalex.org/W2105590818","https://openalex.org/W2105606912","https://openalex.org/W2106059830","https://openalex.org/W2106814841","https://openalex.org/W2108563485","https://openalex.org/W2112353908","https://openalex.org/W2113855243","https://openalex.org/W2123291196","https://openalex.org/W2131933271","https://openalex.org/W2132718532","https://openalex.org/W2134954458","https://openalex.org/W2137853407","https://openalex.org/W2141185001","https://openalex.org/W2141217745","https://openalex.org/W2141949088","https://openalex.org/W2142917245","https://openalex.org/W2147145155","https://openalex.org/W2149830465","https://openalex.org/W2150784816","https://openalex.org/W2153278490","https://openalex.org/W2154368751","https://openalex.org/W2154707206","https://openalex.org/W2155545930","https://openalex.org/W2158959181","https://openalex.org/W2162233555","https://openalex.org/W2164380839","https://openalex.org/W2165693067","https://openalex.org/W2168812806","https://openalex.org/W2169935124","https://openalex.org/W2246815095","https://openalex.org/W2334926852","https://openalex.org/W2396430464","https://openalex.org/W2398761484","https://openalex.org/W2405132130","https://openalex.org/W2409049324","https://openalex.org/W2409073516","https://openalex.org/W2410340436","https://openalex.org/W2410819816","https://openalex.org/W2410823076","https://openalex.org/W2415541713","https://openalex.org/W2416444983","https://openalex.org/W2417407005","https://openalex.org/W2422890339","https://openalex.org/W2434137812","https://openalex.org/W2434423289","https://openalex.org/W2461366773","https://openalex.org/W2462224552","https://openalex.org/W2495575533","https://openalex.org/W2572695012","https://openalex.org/W2763982512","https://openalex.org/W2779985567","https://openalex.org/W4312908636","https://openalex.org/W4319704867","https://openalex.org/W4323283752"],"related_works":["https://openalex.org/W3044202259","https://openalex.org/W2410340436","https://openalex.org/W4319065573","https://openalex.org/W2978725962","https://openalex.org/W2800307179","https://openalex.org/W2410823076","https://openalex.org/W2049012251","https://openalex.org/W2626043678","https://openalex.org/W7096736565","https://openalex.org/W1991289593"],"abstract_inverted_index":{"In":[0],"this":[1,119,260,288,338,450],"thesis,":[2],"the":[3,23,28,59,69,116,152,165,169,185,188,277,293,302,306,319,323,327,341,391,425,434,466,479],"complexity":[4],"of":[5,30,56,71,83,95,101,115,151,164,181,184,202,226,234,244,287,296,301,330,345,355,360,393,417,427,439,443],"surgical":[6,37,73,84,154,207,294,328,468],"treatment":[7,65,295,329],"for":[8,40,86,124,149,223,461],"failed":[9,87],"antireflux":[10,31,51,88,135,155,209,235,270,384,457],"procedures":[11,38],"and":[12,80,111,143,229,248,315,375],"large":[13,297,331,347,400,472],"hiatal":[14,176,298,332,348,401,473],"hernias":[15],"(type":[16],"II-IV)":[17],"is":[18,66,75,137,322,351,396,411,422,481],"described.":[19],"The":[20,284],"studies":[21],"in":[22,54,58,68,77,107,118,190,200,269,326,337,353,369,413,437,449,453],"first":[24],"part":[25,183,286],"have":[26],"addressed":[27],"results":[29],"surgery":[32,52,89,136,199,210],"after":[33,211],"previous":[34,153,213,254],"endoscopic":[35],"or":[36,174,407,487],"performed":[39,460],"refractory":[41,462],"gastro-oesophageal":[42,166,463],"reflux":[43,282,405,464],"disease.":[44],"It":[45,334],"was":[46,105,195,335,379,447],"previously":[47],"shown":[48,106,336,448],"that":[49,340],"primary":[50,102,206],"fails":[53],"10-15%":[55],"patients":[57,373,418],"long":[60],"run":[61],"and,":[62],"although":[63],"conservative":[64],"adequate":[67],"majority":[70],"patients,":[72,361],"reintervention":[74,85],"necessary":[76],"3-6%.":[78],"Symptomatic":[79],"objective":[81],"outcomes":[82],"are,":[90],"with":[91,139,187,240,279,374,455,484],"a":[92,108,112,182,212,241,253,394,414,420,428],"success":[93],"rate":[94],"70-80%,":[96],"substantially":[97],"lower":[98],"than":[99],"those":[100],"surgery,":[103,236,271],"as":[104,272,404],"cohort":[109],"study":[110],"systematic":[113],"review":[114],"literature":[117],"thesis.":[120],"Herein,":[121,424],"risk":[122,243,267],"factors":[123],"renewed":[125],"failure":[126,150],"appeared":[127],"to":[128,131,205,219,230,281,477],"be":[129,238,263],"difficult":[130],"identify.":[132],"Additionally,":[133,445],"redo":[134,198],"accompanied":[138,239,483],"relative":[140],"high":[141],"morbidity":[142],"even":[144],"mortality.":[145],"An":[146],"anatomical":[147,364,377,389],"explanation":[148],"procedure,":[156],"including":[157,309],"wrap":[158,172,189],"disruption,":[159],"telescoping":[160],"(ie,":[161,178],"cephalad":[162],"migration":[163,180],"junction":[167],"through":[168],"wrap),":[170],"intrathoracic":[171,179],"migration,":[173],"para-oesophageal":[175],"herniation":[177],"stomach":[186],"its":[191],"normal":[192],"subdiaphragmatic":[193],"position),":[194],"found":[196],"during":[197,399,470],"90%":[201,354],"patients.":[203,356],"Compared":[204],"procedures,":[208],"endoluminal":[214,255],"EsophyX":[215,256],"fundoplication,":[216],"recently":[217],"introduced":[218],"offer":[220],"an":[221,265,383,456],"alternative":[222],"life-long":[224],"use":[225],"antisecretory":[227],"drugs":[228],"avoid":[231],"prolonged":[232],"recuperation":[233],"may":[237],"higher":[242],"intraoperative":[245],"gastric":[246],"injury":[247],"postoperative":[249,313],"troublesome":[250],"dysphagia.":[251,444],"However,":[252],"fundoplication":[257,385,395,421,429,458],"should,":[258],"at":[259],"stage,":[261],"not":[262,275,380,387,431,482],"considered":[264],"additional":[266],"factor":[268],"it":[273,446],"does":[274,386,430],"influence":[276,433],"outcome":[278,344,371,436],"regard":[280],"control.":[283],"second":[285],"thesis":[289,339,451],"has":[290,363],"focused":[291],"on":[292],"hernias.":[299,333],"Because":[300],"documented":[303],"advantages":[304],"over":[305],"open":[307],"repair,":[308,403,475],"less":[310,312],"complications,":[311],"pain,":[314],"shorter":[316],"hospital":[317],"stay,":[318],"laparoscopic":[320,346,471],"repair":[321,350],"preferred":[324],"approach":[325],"long-term":[342],"symptomatic":[343,370,435],"hernia":[349,402,474],"satisfactory":[352],"A":[357,367],"substantial":[358,415],"number":[359,416],"however,":[362],"recurrence":[365,378],"(30%).":[366],"difference":[368],"between":[372],"without":[376],"found.":[381],"Although":[382],"prevent":[388],"recurrence,":[390],"addition":[392,426],"strongly":[397],"recommended":[398],"oesophagitis":[406],"pathological":[408],"acid":[409],"exposure":[410],"induced":[412],"if":[419],"omitted.":[423],"negatively":[432],"terms":[438],"new-onset":[440],"daily":[441],"complaints":[442],"that,":[452],"comparison":[454],"primarily":[459],"disease,":[465],"extensive":[467],"dissection":[469],"required":[476],"restore":[478],"anatomy,":[480],"more":[485,488],"frequent":[486],"severe":[489],"dyspeptic":[490],"symptoms.":[491]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}