{"id":"https://openalex.org/W1600384164","doi":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","title":"Complement Deficiency and Antibody Profile in Survivors of Meningococcal Meningitis due to common Serogroups in Italy","display_name":"Complement Deficiency and Antibody Profile in Survivors of Meningococcal Meningitis due to common Serogroups in Italy","publication_year":1992,"publication_date":"1992-05-01","ids":{"openalex":"https://openalex.org/W1600384164","doi":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","mag":"1600384164","pmid":"https://pubmed.ncbi.nlm.nih.gov/1579859"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-3083.1992.tb03258.x","doi":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","pdf_url":null,"source":{"id":"https://openalex.org/S79173686","display_name":"Scandinavian Journal of Immunology","issn_l":"0300-9475","issn":["0300-9475","1365-3083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2108/64669","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016933710","display_name":"Raffaele D\u2019Amelio","orcid":"https://orcid.org/0000-0003-0669-2629","observed_orcids":["https://orcid.org/0000-0003-0669-2629"]},"institutions":[{"id":"https://openalex.org/I4405261151","display_name":"Aeronautica Militare","ror":"https://ror.org/04w9m1f21","country_code":"IT","type":"government","lineage":["https://openalex.org/I4210114321","https://openalex.org/I4405261151"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"R D'Amelio","raw_affiliation_strings":["Aeronautica Militare Italiana, DASRS, Laboratorio di Immunologia, Pratica di Mare, Roma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aeronautica Militare Italiana, DASRS, Laboratorio di Immunologia, Pratica di Mare, Roma, Italy","institution_ids":["https://openalex.org/I4405261151"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022485785","display_name":"Angelo Agostoni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Agostoni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001539726","display_name":"Roberto Biselli","orcid":"https://orcid.org/0000-0001-7606-4527","observed_orcids":["https://orcid.org/0000-0001-7606-4527"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Biselli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078017580","display_name":"Melchiorre Brai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Brai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065668494","display_name":"G Caruso","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Caruso","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073049397","display_name":"Marco Cicardi","orcid":"https://orcid.org/0000-0003-1251-225X","observed_orcids":["https://orcid.org/0000-0003-1251-225X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Cicardi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034321518","display_name":"Angelo Corvetta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Corvetta","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"L Fontana","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Fontana","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006566337","display_name":"Gabriella Misiano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Misiano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5053063613","display_name":"Roberto Perricone","orcid":"https://orcid.org/0000-0002-2368-9766","observed_orcids":["https://orcid.org/0000-0002-2368-9766"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Perricone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":1.4416,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.77749121,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"35","issue":"5","first_page":"589","last_page":"596"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.8511000275611877,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.8511000275611877,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.14659999310970306,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complement-deficiency","display_name":"complement deficiency","score":0.9020000100135803},{"id":"https://openalex.org/keywords/meningococcal-meningitis","display_name":"meningococcal meningitis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/meningococcal-serogroup-c","display_name":"meningococcal serogroup C","score":0.847000002861023},{"id":"https://openalex.org/keywords/terminal-complement-components","display_name":"terminal complement components","score":0.746999979019165},{"id":"https://openalex.org/keywords/c6-deficiency","display_name":"C6 deficiency","score":0.9810000061988831},{"id":"https://openalex.org/keywords/capsular-polysaccharide-antibodies","display_name":"capsular polysaccharide antibodies","score":0.7990000247955322},{"id":"https://openalex.org/keywords/meningococcal-polysaccharide-vaccine","display_name":"meningococcal polysaccharide vaccine","score":0.6940000057220459},{"id":"https://openalex.org/keywords/recurrent-meningitis","display_name":"recurrent meningitis","score":0.6869999766349792},{"id":"https://openalex.org/keywords/tetanus-toxoid-antibodies","display_name":"tetanus toxoid antibodies","score":0.8159999847412109},{"id":"https://openalex.org/keywords/immunological-abnormalities","display_name":"immune abnormalities","score":0.3449999988079071},{"id":"https://openalex.org/keywords/italy","display_name":"Italy","score":0.4959999918937683}],"concepts":[{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.7956603765487671},{"id":"https://openalex.org/C2908838209","wikidata":"https://www.wikidata.org/wiki/Q890785","display_name":"Meningococcal meningitis","level":4,"score":0.68719881772995},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6697479486465454},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6145421862602234},{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.6112214922904968},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5815922617912292},{"id":"https://openalex.org/C2776645655","wikidata":"https://www.wikidata.org/wiki/Q890785","display_name":"Meningococcal disease","level":4,"score":0.5295133590698242},{"id":"https://openalex.org/C2777351567","wikidata":"https://www.wikidata.org/wiki/Q908822","display_name":"Toxoid","level":4,"score":0.48817044496536255},{"id":"https://openalex.org/C2779841045","wikidata":"https://www.wikidata.org/wiki/Q47790","display_name":"Tetanus","level":3,"score":0.41211143136024475},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.3554534316062927},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2711431086063385},{"id":"https://openalex.org/C2780801004","wikidata":"https://www.wikidata.org/wiki/Q1415366","display_name":"Immunization","level":3,"score":0.22253164649009705},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.13042646646499634},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.053637921810150146},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000907","descriptor_name":"Antibodies, Bacterial","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003165","descriptor_name":"Complement System Proteins","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":true},{"descriptor_ui":"D003183","descriptor_name":"Complement C6","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D003184","descriptor_name":"Complement C7","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D003185","descriptor_name":"Complement C8","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007074","descriptor_name":"Immunoglobulin G","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008585","descriptor_name":"Meningitis, Meningococcal","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009345","descriptor_name":"Neisseria meningitidis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011135","descriptor_name":"Polysaccharides, Bacterial","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016130","descriptor_name":"Immunophenotyping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1111/j.1365-3083.1992.tb03258.x","doi":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1365-3083.1992.tb03258.x","pdf_url":null,"source":{"id":"https://openalex.org/S79173686","display_name":"Scandinavian Journal of Immunology","issn_l":"0300-9475","issn":["0300-9475","1365-3083"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:1579859","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1579859","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scandinavian journal of immunology","raw_type":"Journal Article"},{"id":"pmh:oai:art.torvergata.it:2108/64669","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2108/64669","pdf_url":null,"source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.uniroma1.it:11573/246674","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/246674","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:art.torvergata.it:2108/64669","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2108/64669","pdf_url":null,"source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2438565717","https://openalex.org/W2416694124","https://openalex.org/W2470119948","https://openalex.org/W2100398762","https://openalex.org/W2059665329","https://openalex.org/W2093064710","https://openalex.org/W2057333152","https://openalex.org/W1966042875","https://openalex.org/W2014378212","https://openalex.org/W7164813582"],"abstract_inverted_index":{"A":[0,159],"collaborative":[1],"survey":[2],"was":[3,23,112],"carried":[4],"out":[5,185],"in":[6,64,98,204,270,282,294,310,320],"Italy":[7,295],"on":[8],"a":[9,15,201,209,307],"group":[10,103,141,158],"of":[11,18,28,33,53,59,68,72,76,80,88,124,137,151,183,186,206,257,264,314],"59":[12,165],"subjects":[13,82,166,189,311,321],"with":[14,45,57,83,100,104,140,154,195,211,286,303,312,322],"past":[16],"history":[17],"meningococcal":[19,109,129,265,304],"meningitis.":[20],"The":[21,108],"aim":[22],"to":[24,128,147,157,221],"evaluate":[25],"the":[26,31,37,46,51,60,81,92,101,113,120,125,138,152,180,187,196,215,222,224,227,250,253,271,275,280,284],"prevalence":[27,255],"complement":[29,84,106,212,259,288,323],"deficiencies,":[30],"serogroup":[32,276],"meningococci":[34],"responsible":[35,278],"for":[36,179,279],"disease":[38],"and":[39,63,74,90,117,149,160,296],"other":[40],"possible":[41],"immune":[42],"abnormalities":[43],"associated":[44],"infection.":[47],"Complement":[48],"analysis":[49],"allowed":[50],"detection":[52],"10":[54],"cases":[55,67,285],"(17%)":[56,256],"deficiencies":[58,85],"terminal":[61],"components,":[62],"particular":[65],"six":[66,205],"C8":[69],"beta,":[70],"three":[71],"C7":[73],"one":[75],"C6":[77],"defect.":[78,213,324],"Half":[79],"had":[86,143],"recurrences":[87],"meningitis":[89,155,266],"developed":[91],"infection":[93],"at":[94,176],"an":[95],"older":[96],"age":[97],"comparison":[99],"control":[102],"normal":[105,177,202],"activity.":[107],"C":[110,142],"strain":[111],"most":[114],"diffuse":[115],"(68%)":[116],"infected":[118],"all":[119,164,283],"complement-deficient":[121],"subjects.":[122],"Evaluation":[123],"antibody":[126],"response":[127,203],"capsular":[130],"polysaccharides":[131],"(PS)":[132],"showed":[133],"that":[134],"only":[135],"42.5%":[136],"individuals":[139],"antibodies":[144,194,225,240,316],"as":[145,169,171,317,319],"opposed":[146],"83%":[148],"100%":[150],"patients":[153],"due":[156],"B,":[161],"respectively.":[162],"In":[163,214],"serum":[167],"Ig":[168],"well":[170,318],"IgG":[172],"subclasses":[173],"were":[174,233,241],"present,":[175],"levels":[178],"age.":[181],"Vaccination":[182],"seven":[184],"24":[188],"without":[190],"detectable":[191],"anti-meningococcal":[192],"PS":[193,198,230,305],"sole":[197],"A+C":[199],"induced":[200],"them,":[207],"including":[208],"subject":[210,216],"who":[217],"did":[218],"not":[219],"respond":[220],"antigen,":[223],"against":[226],"ubiquitous":[228],"pneumococcal":[229],"type":[231],"14":[232],"also":[234,268],"lacking,":[235],"whereas":[236],"anti-tetanus":[237],"toxoid":[238],"(TT)":[239],"normally":[242],"present.":[243],"From":[244],"these":[245],"data":[246],"we":[247],"may":[248],"conclude":[249],"following:":[251],"(1)":[252],"high":[254],"late":[258,287],"components":[260,289],"defect":[261],"among":[262],"survivors":[263],"is":[267,291,306],"confirmed":[269],"Italian":[272],"population;":[273],"(2)":[274],"C,":[277],"infections":[281],"defect,":[290],"highly":[292],"recirculating":[293],"apparently":[297],"less":[298],"immunogenic;":[299],"(3)":[300],"specific":[301,315],"vaccination":[302],"valid":[308],"prophylaxis":[309],"lack":[313]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}