{"id":"https://openalex.org/W1595049684","doi":"https://doi.org/10.1038/82858","title":"PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation","display_name":"PI-3 kinase and IP3 are both necessary and sufficient to mediate NT3-induced synaptic potentiation","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W1595049684","doi":"https://doi.org/10.1038/82858","mag":"1595049684","pmid":"https://pubmed.ncbi.nlm.nih.gov/11135641"},"language":"en","primary_location":{"id":"doi:10.1038/82858","doi":"https://doi.org/10.1038/82858","is_oa":false,"landing_page_url":"https://doi.org/10.1038/82858","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100698896","display_name":"Feng Yang","orcid":"https://orcid.org/0000-0003-1275-6641","observed_orcids":["https://orcid.org/0000-0003-1275-6641","https://orcid.org/0000-0002-3637-814X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Feng Yang","raw_affiliation_strings":["Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, Maryland 20892, USA","Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, Maryland 20892, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]},{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100521338","display_name":"Xiangping He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiang-ping He","raw_affiliation_strings":["Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113566217","display_name":"Linyin Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Linyin Feng","raw_affiliation_strings":["Institutes of Neuroscience, Shanghai, 200031, China","Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institutes of Neuroscience, Shanghai, 200031, China","institution_ids":[]},{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086626216","display_name":"Keiko Mizuno","orcid":"https://orcid.org/0000-0001-8689-1956","observed_orcids":["https://orcid.org/0000-0001-8689-1956"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keiko Mizuno","raw_affiliation_strings":["Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xu-Wen Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xu-Wen Liu","raw_affiliation_strings":["Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113977290","display_name":"James T. Russell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Russell","raw_affiliation_strings":["Section on Cell Biology and Signal Transduction, Laboratory of Molecular and Cellular Neurophysiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Cell Biology and Signal Transduction, Laboratory of Molecular and Cellular Neurophysiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065643695","display_name":"Wen\u2010Cheng Xiong","orcid":"https://orcid.org/0000-0001-9071-7598","observed_orcids":["https://orcid.org/0000-0001-9071-7598"]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wen-Cheng Xiong","raw_affiliation_strings":["Department of Pathology, University of Alabama at Birmingham, Birmingham, 35294, Alabama, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Alabama at Birmingham, Birmingham, 35294, Alabama, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060056784","display_name":"Bai Lu","orcid":"https://orcid.org/0000-0001-5418-9759","observed_orcids":["https://orcid.org/0000-0001-5418-9759"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Bai Lu","raw_affiliation_strings":["Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit on Synapse Development & Plasticity, Laboratory of Developmental Neurobiology, NICHD, NIH, Bethesda, 20892, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5060056784"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":5.8882,"has_fulltext":false,"cited_by_count":107,"citation_normalized_percentile":{"value":0.97401984,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"4","issue":"1","first_page":"19","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.5297999978065491,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10483","display_name":"Nerve injury and regeneration","score":0.4311999976634979,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurotrophin-3","display_name":"neurotrophin-3","score":0.9850000143051147},{"id":"https://openalex.org/keywords/synaptic-potentiation","display_name":"synaptic potentiation","score":0.8840000033378601},{"id":"https://openalex.org/keywords/phosphatidylinositol-3-kinase","display_name":"phosphatidylinositol 3-kinase","score":0.9049999713897705},{"id":"https://openalex.org/keywords/inositol-trisphosphate","display_name":"inositol trisphosphate","score":0.8389999866485596},{"id":"https://openalex.org/keywords/ip3-receptor","display_name":"IP3 receptor","score":0.8930000066757202},{"id":"https://openalex.org/keywords/phospholipase-c-gamma","display_name":"phospholipase C-gamma","score":0.9900000095367432},{"id":"https://openalex.org/keywords/neuromuscular-synapse","display_name":"neuromuscular synapse","score":0.8489999771118164},{"id":"https://openalex.org/keywords/motor-neurons","display_name":"motor neurons","score":0.7129999995231628},{"id":"https://openalex.org/keywords/neurotransmitter-release","display_name":"neurotransmitter release","score":0.6480000019073486},{"id":"https://openalex.org/keywords/calcium-release","display_name":"calcium release","score":0.5559999942779541}],"concepts":[{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.8187689185142517},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.6495438814163208},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5511056780815125},{"id":"https://openalex.org/C2778597717","wikidata":"https://www.wikidata.org/wiki/Q420248","display_name":"Phospholipase C","level":3,"score":0.5197453498840332},{"id":"https://openalex.org/C92020748","wikidata":"https://www.wikidata.org/wiki/Q420457","display_name":"Neurotrophin","level":3,"score":0.4790826439857483},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45186948776245117},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.42144066095352173},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4078215956687927},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.36491459608078003},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.24383842945098877},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1174052357673645}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D007527","descriptor_name":"Isoenzymes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D009469","descriptor_name":"Neuromuscular Junction","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010738","descriptor_name":"Type C Phospholipases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010782","descriptor_name":"Photolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014981","descriptor_name":"Xenopus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015220","descriptor_name":"Calcium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D015544","descriptor_name":"Inositol 1,4,5-Trisphosphate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D015544","descriptor_name":"Inositol 1,4,5-Trisphosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015544","descriptor_name":"Inositol 1,4,5-Trisphosphate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017774","descriptor_name":"Long-Term Potentiation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018160","descriptor_name":"Receptors, Cytoplasmic and Nuclear","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020928","descriptor_name":"Mitogen-Activated Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020933","descriptor_name":"Neurotrophin 3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020933","descriptor_name":"Neurotrophin 3","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D051966","descriptor_name":"Phospholipase C gamma","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053496","descriptor_name":"Inositol 1,4,5-Trisphosphate Receptors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/82858","doi":"https://doi.org/10.1038/82858","is_oa":false,"landing_page_url":"https://doi.org/10.1038/82858","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},{"id":"pmid:11135641","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11135641","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature neuroscience","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1529396499","https://openalex.org/W1568605582","https://openalex.org/W1587932799","https://openalex.org/W1597778600","https://openalex.org/W1608930463","https://openalex.org/W1748293968","https://openalex.org/W1850687213","https://openalex.org/W1863049993","https://openalex.org/W1897264013","https://openalex.org/W1967548980","https://openalex.org/W1971263143","https://openalex.org/W1979305117","https://openalex.org/W1982630258","https://openalex.org/W1984929819","https://openalex.org/W1985562091","https://openalex.org/W1992931949","https://openalex.org/W1994088328","https://openalex.org/W1995676396","https://openalex.org/W2001385914","https://openalex.org/W2005764639","https://openalex.org/W2014075858","https://openalex.org/W2020244870","https://openalex.org/W2027496708","https://openalex.org/W2029863311","https://openalex.org/W2035936653","https://openalex.org/W2039379548","https://openalex.org/W2044712342","https://openalex.org/W2044885256","https://openalex.org/W2065021869","https://openalex.org/W2072115446","https://openalex.org/W2074698464","https://openalex.org/W2087081892","https://openalex.org/W2091758977","https://openalex.org/W2092109656","https://openalex.org/W2114996039","https://openalex.org/W2117442410","https://openalex.org/W2124748602","https://openalex.org/W2125403403","https://openalex.org/W2126793143","https://openalex.org/W2128960139","https://openalex.org/W2134678910","https://openalex.org/W2138497185","https://openalex.org/W2152186846","https://openalex.org/W2153279852","https://openalex.org/W2156945415","https://openalex.org/W2163639252","https://openalex.org/W2239081232","https://openalex.org/W2252785765"],"related_works":["https://openalex.org/W1583540378","https://openalex.org/W2001385914","https://openalex.org/W7096232612","https://openalex.org/W1538257464","https://openalex.org/W1988971473","https://openalex.org/W2344383442","https://openalex.org/W1867891474","https://openalex.org/W2611759653","https://openalex.org/W2293968066","https://openalex.org/W2422604119"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}