{"id":"https://openalex.org/W1591978428","doi":null,"title":"Exocrine pancreatic function during the early recovery phase of acute pancreatitis.","display_name":"Exocrine pancreatic function during the early recovery phase of acute pancreatitis.","publication_year":2009,"publication_date":"2009-06-01","ids":{"openalex":"https://openalex.org/W1591978428","mag":"1591978428","pmid":"https://pubmed.ncbi.nlm.nih.gov/19502175"},"language":"en","primary_location":{"id":"pmid:19502175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19502175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatobiliary & pancreatic diseases international : HBPD INT","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048017669","display_name":"Raffaele Pezzilli","orcid":"https://orcid.org/0000-0001-9827-7451","observed_orcids":["https://orcid.org/0000-0001-9827-7451"]},"institutions":[{"id":"https://openalex.org/I4210097083","display_name":"IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola","ror":"https://ror.org/00t4vnv68","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210097083"]},{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaele Pezzilli","raw_affiliation_strings":["Department of Digestive Diseases and Internal Medicine, University of Bologna, Sant'Orsola-Malpighi Hospital, Bologna, Italy. raffaele.pezzilli@aosp.bo.it"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Digestive Diseases and Internal Medicine, University of Bologna, Sant'Orsola-Malpighi Hospital, Bologna, Italy. raffaele.pezzilli@aosp.bo.it","institution_ids":["https://openalex.org/I4210097083","https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002377182","display_name":"Patrizia Simoni","orcid":"https://orcid.org/0000-0001-8581-3585","observed_orcids":["https://orcid.org/0000-0001-8581-3585"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrizia Simoni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065743678","display_name":"Riccardo Casadei","orcid":"https://orcid.org/0000-0001-9486-8190","observed_orcids":["https://orcid.org/0000-0001-9486-8190","https://orcid.org/0000-0002-3253-2162"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Riccardo Casadei","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109199809","display_name":"Antonio Maria Morselli\u2010Labate","orcid":"https://orcid.org/0000-0001-9318-8564","observed_orcids":["https://orcid.org/0000-0001-9318-8564"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Antonio M Morselli-Labate","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.4522,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.91283125,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"8","issue":"3","first_page":"316","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10760","display_name":"Pancreatitis Pathology and Treatment","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10518","display_name":"Gallbladder and Bile Duct Disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-pancreatitis","display_name":"acute pancreatitis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/exocrine-pancreatic-function","display_name":"pancreatic exocrine function","score":0.9599999785423279},{"id":"https://openalex.org/keywords/fecal-elastase-1","display_name":"fecal elastase","score":0.9929999709129333},{"id":"https://openalex.org/keywords/refeeding","display_name":"refeeding","score":0.8370000123977661},{"id":"https://openalex.org/keywords/biliary-pancreatitis","display_name":"biliary pancreatitis","score":0.9670000076293945},{"id":"https://openalex.org/keywords/alcoholic-pancreatitis","display_name":"alcoholic pancreatitis","score":0.8199999928474426},{"id":"https://openalex.org/keywords/hypertriglyceridemia-induced-pancreatitis","display_name":"hypertriglyceridemia-induced pancreatitis","score":0.9610000252723694},{"id":"https://openalex.org/keywords/pancreatic-insufficiency","display_name":"pancreatic insufficiency","score":0.7310000061988831},{"id":"https://openalex.org/keywords/pancreatic-enzyme-replacement-therapy","display_name":"pancreatic enzyme replacement therapy","score":0.5849999785423279}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9175457954406738},{"id":"https://openalex.org/C2775967933","wikidata":"https://www.wikidata.org/wiki/Q1527888","display_name":"Pancreatitis","level":2,"score":0.8332880139350891},{"id":"https://openalex.org/C2776670229","wikidata":"https://www.wikidata.org/wiki/Q854573","display_name":"Acute pancreatitis","level":2,"score":0.830956220626831},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.7925421595573425},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7279230952262878},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.5376876592636108},{"id":"https://openalex.org/C2776737053","wikidata":"https://www.wikidata.org/wiki/Q7130407","display_name":"Pancreatic disease","level":3,"score":0.4928724765777588},{"id":"https://openalex.org/C2776919658","wikidata":"https://www.wikidata.org/wiki/Q1467339","display_name":"Hypertriglyceridemia","level":4,"score":0.4674932062625885},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.4444039463996887},{"id":"https://openalex.org/C2778764654","wikidata":"https://www.wikidata.org/wiki/Q9618","display_name":"Pancreas","level":2,"score":0.20019036531448364},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.07564932107925415},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001660","descriptor_name":"Biliary Tract Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005502","descriptor_name":"Food","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010195","descriptor_name":"Pancreatitis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D010195","descriptor_name":"Pancreatitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010195","descriptor_name":"Pancreatitis","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010196","descriptor_name":"Pancreatic Elastase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015228","descriptor_name":"Hypertriglyceridemia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019512","descriptor_name":"Pancreatitis, Alcoholic","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D020127","descriptor_name":"Recovery of Function","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046790","descriptor_name":"Pancreas, Exocrine","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:19502175","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19502175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hepatobiliary & pancreatic diseases international : HBPD INT","raw_type":"Journal Article"},{"id":"pmh:oai:cris.unibo.it:11585/81626","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/81626","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:1591978428","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19502175","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W23065507","https://openalex.org/W48464366","https://openalex.org/W1984595933","https://openalex.org/W1985045980","https://openalex.org/W1990009667","https://openalex.org/W1998588680","https://openalex.org/W2017528013","https://openalex.org/W2028844827","https://openalex.org/W2057853279","https://openalex.org/W2081412472","https://openalex.org/W2092413092","https://openalex.org/W2093489702","https://openalex.org/W2168039302","https://openalex.org/W2180255985","https://openalex.org/W2412729325"],"related_works":["https://openalex.org/W2037497085","https://openalex.org/W2093489702","https://openalex.org/W2046788045","https://openalex.org/W2377733811","https://openalex.org/W3143968346","https://openalex.org/W2121651798","https://openalex.org/W7097834713","https://openalex.org/W23065507","https://openalex.org/W2348179948","https://openalex.org/W4412488476"],"abstract_inverted_index":{"BACKGROUND:":[0],"Exocrine":[1,230],"pancreatic":[2,31,231,254],"dysfunction":[3],"has":[4],"been":[5],"reported":[6],"in":[7,9,33,54,111,139,185,193,237,247],"humans":[8],"the":[10,17,29,39,50,65,112,123,142,163,178,243],"convalescent":[11],"period":[12],"after":[13,122],"acute":[14,36,57,77,85,107,126,240],"pancreatitis,":[15],"but":[16],"data":[18],"are":[19],"scarce":[20],"and":[21,79,99,152,207],"conflicting.":[22],"This":[23],"study":[24],"aimed":[25],"to":[26,222,249],"prospectively":[27],"assess":[28],"exocrine":[30],"function":[32,232],"patients":[34,59,70,74,82,89,115,144,148,155,186,238],"with":[35,60,75,83,149,156,187,196,202,210,239,253],"pancreatitis":[37,58,78,108,127,151,158,189,198,204,212,241],"at":[38,242],"time":[40,121,244],"of":[41,52,64,106,125,134,141,162,166,174,177,227,245],"their":[42,61,251],"refeeding.":[43,228],"METHODS:":[44],"Fecal":[45],"elastase-1":[46,136,168,217],"was":[47,128,169,182,218],"determined":[48],"on":[49],"day":[51,226],"refeeding":[53,120,246],"all":[55],"consecutive":[56],"first":[62],"episode":[63],"disease.":[66],"They":[67],"were":[68,109,137],"75":[69,143],"including":[71],"60":[72],"(80.0%)":[73],"mild":[76,150],"15":[80],"(20.0%)":[81],"severe":[84,157],"pancreatitis.":[86],"Etiologically":[87],"61":[88],"(81.3%)":[90],"had":[91,96,102],"biliary":[92,188],"disease,":[93],"1":[94],"(1.3%)":[95],"alcoholic":[97,197],"disease":[98,179],"3":[100],"(4.0%)":[101],"hypertriglyceridemia.":[103],"No":[104],"causes":[105],"found":[110,138],"remaining":[113],"10":[114],"(13.3%).":[116],"The":[117,160],"mean":[118],"(+/-SD)":[119],"attack":[124],"11.2+/-10.2":[129],"days.":[130],"RESULTS:":[131],"Pathological":[132,215],"values":[133,165],"fecal":[135,167,216],"9":[140],"(12.0%):":[145],"7":[146],"(9.3%)":[147],"2":[153],"(2.7%)":[154],"(P=1.000).":[159],"frequency":[161],"pathological":[164],"significantly":[170,183,220],"different":[171],"from":[172],"that":[173],"various":[175],"etiologies":[176],"(P=0.030).":[180],"It":[181],"lower":[184],"(9.8%;":[190],"P=0.035)":[191],"than":[192],"one":[194,200,208],"patient":[195,201,209],"(P=0.126),":[199],"hypertriglyceridemia-induced":[203],"(33.3%;":[205],"P=0.708),":[206],"idiopathic":[211],"(10.0%;":[213],"P=0.227).":[214],"not":[219],"related":[221],"sex,":[223],"age":[224],"or":[225],"CONCLUSION:":[229],"should":[233],"be":[234],"routinely":[235],"assessed":[236],"order":[248],"supplement":[250],"diet":[252],"extracts.":[255]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}