{"id":"https://openalex.org/W1586804243","doi":null,"title":"Rimonabant for treating tobacco dependence.","display_name":"Rimonabant for treating tobacco dependence.","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1586804243","mag":"1586804243","pmid":"https://pubmed.ncbi.nlm.nih.gov/17703638","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2293960"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2293960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2293960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vasc Health Risk Manag","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2293960","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032449399","display_name":"Michael B. Steinberg","orcid":"https://orcid.org/0000-0003-2661-2120","observed_orcids":["https://orcid.org/0000-0003-2661-2120","https://orcid.org/0009-0001-2877-6703"]},"institutions":[{"id":"https://openalex.org/I4405286694","display_name":"University of Medicine and Dentistry of New Jersey","ror":"https://ror.org/02tvvmk84","country_code":"US","type":"education","lineage":["https://openalex.org/I102322142","https://openalex.org/I4405286694"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael B Steinberg","raw_affiliation_strings":["University of Medicine and Dentistry of New Jersey-School of Public Health, Tobacco Dependence Program, New Brunswick, NJ 08901, USA. michael.steinberg@umdnj.edu","University of Medicine and Dentistry of New Jersey-School of Public Health, Tobacco Dependence Program, New Brunswick, NJ 08901, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Medicine and Dentistry of New Jersey-School of Public Health, Tobacco Dependence Program, New Brunswick, NJ 08901, USA. michael.steinberg@umdnj.edu","institution_ids":["https://openalex.org/I4405286694"]},{"raw_affiliation_string":"University of Medicine and Dentistry of New Jersey-School of Public Health, Tobacco Dependence Program, New Brunswick, NJ 08901, USA","institution_ids":["https://openalex.org/I4405286694"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005013018","display_name":"Jonathan Foulds","orcid":"https://orcid.org/0000-0003-2296-0726","observed_orcids":["https://orcid.org/0000-0003-2296-0726"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonathan Foulds","raw_affiliation_strings":["Department of Public Health Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4198,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.82316493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"3","issue":"3","first_page":"307","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rimonabant","display_name":"rimonabant","score":1.0},{"id":"https://openalex.org/keywords/tobacco-dependence","display_name":"tobacco dependence","score":0.8799999952316284},{"id":"https://openalex.org/keywords/smoking-cessation","display_name":"smoking cessation","score":0.9829999804496765},{"id":"https://openalex.org/keywords/endocannabinoid-system","display_name":"endocannabinoid system","score":0.9399999976158142},{"id":"https://openalex.org/keywords/cannabinoid-receptor-type-1","display_name":"cannabinoid receptor type 1","score":0.8149999976158142},{"id":"https://openalex.org/keywords/nicotine-reward","display_name":"nicotine reward","score":0.8920000195503235},{"id":"https://openalex.org/keywords/weight-gain-after-quitting-smoking","display_name":"weight gain after quitting smoking","score":0.6769999861717224}],"concepts":[{"id":"https://openalex.org/C2776433454","wikidata":"https://www.wikidata.org/wiki/Q412529","display_name":"Rimonabant","level":5,"score":0.9813238382339478},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9295387268066406},{"id":"https://openalex.org/C2777843972","wikidata":"https://www.wikidata.org/wiki/Q2462253","display_name":"Smoking cessation","level":2,"score":0.7435727715492249},{"id":"https://openalex.org/C2780687700","wikidata":"https://www.wikidata.org/wiki/Q210978","display_name":"Abstinence","level":2,"score":0.7141682505607605},{"id":"https://openalex.org/C2779547902","wikidata":"https://www.wikidata.org/wiki/Q28086552","display_name":"Nicotine","level":2,"score":0.5917960405349731},{"id":"https://openalex.org/C46721173","wikidata":"https://www.wikidata.org/wiki/Q368952","display_name":"Endocannabinoid system","level":3,"score":0.5523433089256287},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5363283157348633},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.44456878304481506},{"id":"https://openalex.org/C62724370","wikidata":"https://www.wikidata.org/wiki/Q7811505","display_name":"Tobacco harm reduction","level":4,"score":0.44350579380989075},{"id":"https://openalex.org/C148001335","wikidata":"https://www.wikidata.org/wiki/Q421237","display_name":"Cannabinoid receptor","level":4,"score":0.42952191829681396},{"id":"https://openalex.org/C2779177420","wikidata":"https://www.wikidata.org/wiki/Q3961638","display_name":"Nicotine withdrawal","level":3,"score":0.4188840091228485},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3227481544017792},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.314928263425827},{"id":"https://openalex.org/C3019190695","wikidata":"https://www.wikidata.org/wiki/Q7212330","display_name":"Tobacco use","level":3,"score":0.2925035357475281},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.278437077999115},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.22398865222930908},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2051003873348236},{"id":"https://openalex.org/C2776885963","wikidata":"https://www.wikidata.org/wiki/Q245204","display_name":"Antagonist","level":3,"score":0.13294771313667297},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.08668920397758484},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.06343060731887817},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077285","descriptor_name":"Rimonabant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D010880","descriptor_name":"Piperidines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011720","descriptor_name":"Pyrazoles","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014029","descriptor_name":"Tobacco Use Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016540","descriptor_name":"Smoking Cessation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D063385","descriptor_name":"Cannabinoid Receptor Modulators","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2293960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2293960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vasc Health Risk Manag","raw_type":"Text"},{"id":"pmid:17703638","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17703638","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vascular health and risk management","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:cf677ee9249b4d659c9c8e84474bca08","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cf677ee9249b4d659c9c8e84474bca08","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Vascular Health and Risk Management, Vol Volume 3, Pp 307-311 (2007)","raw_type":"article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2293960","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2293960","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Vasc Health Risk Manag","raw_type":"Text"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1549559727","https://openalex.org/W1955803833","https://openalex.org/W1971698096","https://openalex.org/W1989008646","https://openalex.org/W2030674555","https://openalex.org/W2036647966","https://openalex.org/W2042273131","https://openalex.org/W2053457282","https://openalex.org/W2070212982","https://openalex.org/W2087587748","https://openalex.org/W2090246977","https://openalex.org/W2096115799","https://openalex.org/W2103508997","https://openalex.org/W2107200746","https://openalex.org/W2127193609","https://openalex.org/W2142225862","https://openalex.org/W2150339336","https://openalex.org/W2163231665","https://openalex.org/W2164386461","https://openalex.org/W2312609348","https://openalex.org/W2324299619","https://openalex.org/W2463861392","https://openalex.org/W3196006573","https://openalex.org/W4206039176"],"related_works":["https://openalex.org/W7099606933","https://openalex.org/W2607127847","https://openalex.org/W4247320809","https://openalex.org/W2376890933","https://openalex.org/W2079074670","https://openalex.org/W1875725323","https://openalex.org/W2098152369","https://openalex.org/W2420927347","https://openalex.org/W2110635658","https://openalex.org/W1987054465"],"abstract_inverted_index":{"Tobacco":[0],"use":[1,27],"continues":[2],"to":[3,40,55,79,91,131,135],"cause":[4],"5":[5],"million":[6],"preventable":[7],"deaths":[8],"worldwide":[9],"each":[10],"year.":[11],"Despite":[12],"effective":[13],"treatments":[14],"being":[15],"available,":[16],"these":[17,116],"are":[18,33],"underutilized":[19],"and":[20,124],"cessation":[21,133],"rates":[22,87],"remain":[23],"low.":[24],"As":[25],"tobacco":[26],"has":[28,52,71],"complex":[29],"physiological":[30],"effects,":[31],"there":[32],"multiple":[34],"opportunities":[35],"for":[36],"novel":[37],"pharmacological":[38],"agents":[39],"play":[41],"a":[42,45,64],"role":[43,127],"in":[44,60,74,84],"comprehensive":[46],"treatment":[47],"plan.":[48],"The":[49],"endocannabinoid":[50],"system":[51],"been":[53,72,121],"linked":[54],"the":[56,100,113],"nicotine":[57],"reward":[58],"pathways":[59],"animal":[61],"models.":[62],"Rimonabant,":[63],"selective":[65],"cannabinoid":[66],"receptor":[67],"(type":[68],"1)":[69],"blocker,":[70],"shown":[73],"some":[75,81],"early":[76],"clinical":[77],"trials":[78,118],"have":[80,119],"positive":[82],"effects":[83],"increasing":[85],"abstinence":[86],"of":[88,102],"smokers":[89,95],"attempting":[90],"stop.":[92],"In":[93],"addition,":[94],"who":[96],"stop":[97],"smoking":[98,132],"with":[99],"assistance":[101],"rimonabant":[103],"may":[104],"gain":[105],"less":[106],"weight":[107],"than":[108],"those":[109],"using":[110],"placebo.":[111],"However,":[112],"results":[114],"from":[115],"few":[117],"not":[120],"entirely":[122],"consistent":[123],"so":[125],"its":[126],"as":[128],"an":[129],"aid":[130],"remains":[134],"be":[136],"determined.":[137]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}