{"id":"https://openalex.org/W1584515765","doi":"https://doi.org/10.1002/ajmg.a.37208","title":"Aortic dimensions in Turner syndrome","display_name":"Aortic dimensions in Turner syndrome","publication_year":2015,"publication_date":"2015-06-27","ids":{"openalex":"https://openalex.org/W1584515765","doi":"https://doi.org/10.1002/ajmg.a.37208","mag":"1584515765","pmid":"https://pubmed.ncbi.nlm.nih.gov/26118429"},"language":"en","primary_location":{"id":"doi:10.1002/ajmg.a.37208","doi":"https://doi.org/10.1002/ajmg.a.37208","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ajmg.a.37208","pdf_url":null,"source":{"id":"https://openalex.org/S180901878","display_name":"American Journal of Medical Genetics Part A","issn_l":"1552-4825","issn":["1552-4825","1552-4833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Medical Genetics Part A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076232469","display_name":"Emilio Quezada","orcid":"https://orcid.org/0000-0002-5405-6136","observed_orcids":["https://orcid.org/0000-0002-5405-6136"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Emilio Quezada","raw_affiliation_strings":["Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008138486","display_name":"Jodi Lapidus","orcid":"https://orcid.org/0000-0002-2068-0619","observed_orcids":["https://orcid.org/0000-0002-2068-0619"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jodi Lapidus","raw_affiliation_strings":["Department of Public Health & Preventive Medicine Oregon Health & Sciences University Portland Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health & Preventive Medicine Oregon Health & Sciences University Portland Oregon","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012619620","display_name":"Robin D. Shaughnessy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robin Shaughnessy","raw_affiliation_strings":["Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005233999","display_name":"Zunqiu Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zunqiu Chen","raw_affiliation_strings":["Department of Public Health & Preventive Medicine Oregon Health & Sciences University Portland Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health & Preventive Medicine Oregon Health & Sciences University Portland Oregon","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053827785","display_name":"Michael Silberbach","orcid":"https://orcid.org/0000-0003-3229-8692","observed_orcids":["https://orcid.org/0000-0003-3229-8692"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Silberbach","raw_affiliation_strings":["Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics Division of Pediatric Cardiology Oregon Health & Sciences University Portland Oregon","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Pediatric Cardiology, Oregon Health & Sciences University, Portland, Oregon","institution_ids":["https://openalex.org/I165690674"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5076232469"],"corresponding_institution_ids":["https://openalex.org/I165690674"],"apc_list":{"value":4710,"currency":"USD","value_usd":4710},"apc_paid":null,"fwci":2.6882,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.89987108,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"167","issue":"11","first_page":"2527","last_page":"2532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.43630000948905945,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.43630000948905945,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.30300000309944153,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11310","display_name":"Connective tissue disorders research","score":0.17980000376701355,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/turner-syndrome","display_name":"Turner syndrome","score":1.0},{"id":"https://openalex.org/keywords/aortic-dimensions","display_name":"aortic dimensions","score":0.8479999899864197},{"id":"https://openalex.org/keywords/aortic-diameter","display_name":"aortic diameter","score":0.8069999814033508},{"id":"https://openalex.org/keywords/reference-curves","display_name":"reference curves","score":0.6209999918937683},{"id":"https://openalex.org/keywords/bicuspid-aortic-valve","display_name":"bicuspid aortic valve","score":0.9039999842643738},{"id":"https://openalex.org/keywords/aortic-dissection","display_name":"aortic dissection","score":0.8190000057220459},{"id":"https://openalex.org/keywords/aortic-rupture","display_name":"aortic rupture","score":0.6970000267028809},{"id":"https://openalex.org/keywords/body-surface-area","display_name":"body surface area","score":0.7110000252723694},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.6420000195503235},{"id":"https://openalex.org/keywords/growth-hormone-therapy","display_name":"growth hormone therapy","score":0.5260000228881836},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.5339999794960022}],"concepts":[{"id":"https://openalex.org/C2779683239","wikidata":"https://www.wikidata.org/wiki/Q202849","display_name":"Turner syndrome","level":2,"score":0.8963456153869629},{"id":"https://openalex.org/C2781355080","wikidata":"https://www.wikidata.org/wiki/Q860167","display_name":"Bicuspid aortic valve","level":3,"score":0.8079301118850708},{"id":"https://openalex.org/C2777501473","wikidata":"https://www.wikidata.org/wiki/Q1796666","display_name":"Body surface area","level":2,"score":0.6726528406143188},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6245330572128296},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.6136241555213928},{"id":"https://openalex.org/C2779993142","wikidata":"https://www.wikidata.org/wiki/Q594660","display_name":"Aortic dissection","level":3,"score":0.6045024394989014},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.579365074634552},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5562475323677063},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.49297213554382324},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.4798109829425812},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D001830","descriptor_name":"Body Surface Area","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003710","descriptor_name":"Demography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014424","descriptor_name":"Turner Syndrome","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D014424","descriptor_name":"Turner Syndrome","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014463","descriptor_name":"Ultrasonography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/ajmg.a.37208","doi":"https://doi.org/10.1002/ajmg.a.37208","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ajmg.a.37208","pdf_url":null,"source":{"id":"https://openalex.org/S180901878","display_name":"American Journal of Medical Genetics Part A","issn_l":"1552-4825","issn":["1552-4825","1552-4833"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Medical Genetics Part A","raw_type":"journal-article"},{"id":"pmid:26118429","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26118429","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of medical genetics. Part A","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G6463605949","display_name":"Oregon Clinical and Translational Research Institute","funder_award_id":"UL1RR024140","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"}],"funders":[{"id":"https://openalex.org/F4320332578","display_name":"Oregon Clinical and Translational Research Institute","ror":"https://ror.org/009avj582"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1986790597","https://openalex.org/W2022948625","https://openalex.org/W2029653395","https://openalex.org/W2035779428","https://openalex.org/W2072371345","https://openalex.org/W2097193342","https://openalex.org/W2109534439","https://openalex.org/W2110292790","https://openalex.org/W2116116891","https://openalex.org/W2119483101","https://openalex.org/W2128831381","https://openalex.org/W2136356633","https://openalex.org/W2139537565","https://openalex.org/W2143954917","https://openalex.org/W2166383227","https://openalex.org/W2288605373"],"related_works":["https://openalex.org/W2774883265","https://openalex.org/W2022948625","https://openalex.org/W1980043911","https://openalex.org/W2101988535","https://openalex.org/W2612955238","https://openalex.org/W1580127438","https://openalex.org/W2790896653","https://openalex.org/W2935852340","https://openalex.org/W4389762534","https://openalex.org/W2306597638"],"abstract_inverted_index":{"In":[0],"Turner":[1,16,30,44,72,109],"syndrome,":[2,17],"linear":[3,123],"growth":[4,150],"is":[5,40],"less":[6],"than":[7,54],"the":[8,38,56,65,70,99,130,173,193],"general":[9,57,67],"population.":[10,58,219],"Consequently,":[11],"to":[12,61,77,91,117,128,160,185,211],"assess":[13,129],"stature":[14],"in":[15,29,43,55,102,113],"condition-specific":[18],"comparators":[19],"have":[20],"been":[21],"employed.":[22],"Similar":[23],"reference":[24,218],"curves":[25],"for":[26,177],"cardiac":[27],"structures":[28],"syndrome":[31,45,73,110],"are":[32],"currently":[33],"unavailable.":[34],"Accurate":[35],"assessment":[36],"of":[37,79,98,132,144],"aorta":[39,101],"particularly":[41],"critical":[42],"because":[46],"aortic":[47,80,93,139,156,163,168,178,213],"dissection":[48],"and":[49,85,106,121,182,188,208],"rupture":[50],"occur":[51],"more":[52],"frequently":[53],"Furthermore,":[59],"comparisons":[60],"references":[62],"calculated":[63,181],"from":[64,115,172,192],"taller":[66],"population":[68,74],"with":[69,108,166],"shorter":[71],"can":[75],"lead":[76],"over-estimation":[78],"size":[81],"causing":[82],"stigmatization,":[83],"medicalization,":[84],"potentially":[86],"over-treatment.":[87],"We":[88],"used":[89],"echocardiography":[90],"measure":[92],"diameters":[94,179],"at":[95],"eight":[96],"levels":[97],"thoracic":[100],"481":[103],"healthy":[104],"girls":[105],"women":[107],"who":[111],"ranged":[112],"age":[114],"two":[116],"seventy":[118],"years.":[119],"Univariate":[120],"multivariate":[122],"regression":[124],"analyses":[125],"were":[126,170,180,195],"performed":[127],"influence":[131],"karyotype,":[133],"age,":[134],"body":[135,198],"mass":[136],"index,":[137],"bicuspid":[138,155,167],"valve,":[140],"blood":[141],"pressure,":[142],"history":[143],"renal":[145],"disease,":[146,148],"thyroid":[147],"or":[149],"hormone":[151],"therapy.":[152],"Because":[153],"only":[154],"valve":[157,169],"was":[158],"found":[159],"independently":[161],"affect":[162],"size,":[164],"subjects":[165],"excluded":[171],"analysis.":[174],"Regression":[175],"equations":[176],"Z-scores":[183,214],"corresponding":[184],"1,":[186],"2,":[187],"3":[189],"standard":[190],"deviations":[191],"mean":[194],"plotted":[196],"against":[197],"surface":[199],"area.":[200],"The":[201],"information":[202],"presented":[203],"here":[204],"will":[205],"allow":[206],"clinicians":[207],"other":[209],"caregivers":[210],"calculate":[212],"using":[215],"a":[216],"Turner-based":[217],"\u00a9":[220],"2015":[221],"Wiley":[222],"Periodicals,":[223],"Inc.":[224]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}