{"id":"https://openalex.org/W158443437","doi":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","title":"Social and emotional factors and decisions of advanced cancer patients (ACP) to enter an early-phase (EP) clinical trial.","display_name":"Social and emotional factors and decisions of advanced cancer patients (ACP) to enter an early-phase (EP) clinical trial.","publication_year":2014,"publication_date":"2014-11-01","ids":{"openalex":"https://openalex.org/W158443437","doi":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","mag":"158443437"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2014.32.31_suppl.223","doi":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060803768","display_name":"Daniel Paul Dohan","orcid":"https://orcid.org/0000-0002-7052-1288","observed_orcids":["https://orcid.org/0000-0002-7052-1288"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Paul Dohan","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002470243","display_name":"James Allen Wiley","orcid":"https://orcid.org/0000-0001-9587-4461","observed_orcids":["https://orcid.org/0000-0001-9587-4461","https://orcid.org/0009-0000-9321-6609"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Wiley","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064407858","display_name":"Sarah B. Garrett","orcid":"https://orcid.org/0000-0002-3238-5692","observed_orcids":["https://orcid.org/0000-0002-3238-5692"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah B. Garrett","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066322516","display_name":"Laura S. Trupin","orcid":"https://orcid.org/0000-0003-4046-200X","observed_orcids":["https://orcid.org/0000-0003-4046-200X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Trupin","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075918212","display_name":"Fay J. Hlubocky","orcid":"https://orcid.org/0000-0002-4647-3597","observed_orcids":["https://orcid.org/0000-0002-4647-3597"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fay J. Hlubocky","raw_affiliation_strings":["The University of Chicago Medicine, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Chicago Medicine, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025048434","display_name":"Christopher K. Daugherty","orcid":"https://orcid.org/0000-0002-5247-6911","observed_orcids":["https://orcid.org/0000-0002-5247-6911"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher Daugherty","raw_affiliation_strings":["The University of Chicago Medicine, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Chicago Medicine, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110808664","display_name":"Anne Reinert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210167126","display_name":"UCSF Helen Diller Family Comprehensive Cancer Center","ror":"https://ror.org/05yndxy10","country_code":"US","type":"facility","lineage":["https://openalex.org/I180670191","https://openalex.org/I4210110664","https://openalex.org/I4210167126"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anne Reinert","raw_affiliation_strings":["UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA","institution_ids":["https://openalex.org/I4210167126"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083373965","display_name":"Pamela N. M\u00fcnster","orcid":"https://orcid.org/0000-0002-2074-0984","observed_orcids":["https://orcid.org/0000-0002-2074-0984","https://orcid.org/0009-0009-4141-2312"]},"institutions":[{"id":"https://openalex.org/I4210167126","display_name":"UCSF Helen Diller Family Comprehensive Cancer Center","ror":"https://ror.org/05yndxy10","country_code":"US","type":"facility","lineage":["https://openalex.org/I180670191","https://openalex.org/I4210110664","https://openalex.org/I4210167126"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela N. Munster","raw_affiliation_strings":["UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA","institution_ids":["https://openalex.org/I4210167126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"32","issue":"31_suppl","first_page":"223","last_page":"223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10177","display_name":"Palliative Care and End-of-Life Issues","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10177","display_name":"Palliative Care and End-of-Life Issues","score":0.6942999958992004,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.23649999499320984,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13340","display_name":"Palliative and Oncologic Care","score":0.03060000017285347,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-cancer-patients","display_name":"advanced cancer patients","score":0.878000020980835},{"id":"https://openalex.org/keywords/psychosocial-factors","display_name":"psychosocial factors","score":0.7160000205039978},{"id":"https://openalex.org/keywords/perceived-control","display_name":"perceived control","score":0.890999972820282},{"id":"https://openalex.org/keywords/depressive-symptoms","display_name":"depressive symptoms","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hope","display_name":"hope","score":0.9520000219345093},{"id":"https://openalex.org/keywords/physician-patient-relationship","display_name":"physician-patient relationship","score":0.7360000014305115},{"id":"https://openalex.org/keywords/information-networks","display_name":"information networks","score":0.8650000095367432},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.8349999785423279}],"concepts":[{"id":"https://openalex.org/C122980154","wikidata":"https://www.wikidata.org/wiki/Q205555","display_name":"Feeling","level":2,"score":0.7898873090744019},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6936429738998413},{"id":"https://openalex.org/C74196892","wikidata":"https://www.wikidata.org/wiki/Q7781188","display_name":"Thematic analysis","level":3,"score":0.6005162596702576},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5251248478889465},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5123025178909302},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.47262832522392273},{"id":"https://openalex.org/C2778087770","wikidata":"https://www.wikidata.org/wiki/Q2297111","display_name":"Social support","level":2,"score":0.41146326065063477},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.3401634097099304},{"id":"https://openalex.org/C190248442","wikidata":"https://www.wikidata.org/wiki/Q839486","display_name":"Qualitative research","level":2,"score":0.30847400426864624},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.23316794633865356},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.22755464911460876},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.18267413973808289},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.17365983128547668},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.14769235253334045},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2014.32.31_suppl.223","doi":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2014.32.31_suppl.223","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2402566080","https://openalex.org/W2770444600","https://openalex.org/W2979591413","https://openalex.org/W4414770488","https://openalex.org/W2541249746","https://openalex.org/W4393150115","https://openalex.org/W4293277380","https://openalex.org/W3158091872","https://openalex.org/W4366601907","https://openalex.org/W3095386500"],"abstract_inverted_index":{"223":[0],"Background:":[1],"We":[2],"explored":[3],"how":[4],"social":[5,112],"and":[6,26,74,83,87,113,129,151,183,195],"emotional":[7,114],"factors":[8,115],"shaped":[9],"decisions":[10],"by":[11],"ACP":[12,29,101,122,169,204],"to":[13,51,106,142,154,157,177,187],"enter":[14],"an":[15,33,38,207],"EP":[16,39,62,108,119,147,208,219],"trial.":[17,209],"Methods:":[18],"Mixed-methods":[19],"longitudinal":[20],"cohort":[21],"study":[22,63],"including":[23],"validated":[24],"surveys":[25],"open-ended":[27],"interviews.":[28],"were":[30,43,80,91,116,139],"recruited":[31],"at":[32],"academic":[34],"medical":[35],"center":[36],"with":[37,118,180,203],"trials":[40],"program.":[41],"Patients":[42],"eligible":[44],"if":[45],"treating":[46],"oncologists":[47],"deemed":[48],"them":[49],"likely":[50,141],"exhaust":[52],"standard":[53],"treatment":[54],"in":[55,99,135],"6-12":[56],"months":[57],"but":[58],"before":[59],"being":[60],"offered":[61],"enrollment.":[64],"Surveys":[65],"measured":[66],"symptoms,":[67],"quality":[68],"of":[69,133,173,193,197,206,212,218],"life,":[70],"decisional":[71],"preferences,":[72],"emotions,":[73],"demographics.":[75],"60":[76],"minute":[77],"semi-structured":[78],"interviews":[79],"audio":[81],"recorded":[82],"transcribed.":[84],"SAS":[85],"(statistical)":[86],"Atlas.ti":[88],"(thematic":[89],"coding)":[90],"use":[92],"for":[93],"analysis.":[94],"Results:":[95],"Of":[96],"82":[97],"patients":[98],"the":[100,216],"cohort,":[102],"16%":[103],"went":[104],"on":[105],"initiate":[107],"trial":[109],"entry.":[110],"No":[111],"associated":[117,202],"initiation":[120,205],"except":[121],"who":[123],"reported":[124],"both":[125],"not":[126],"\u201cfeeling":[127],"down\u201d":[128],"feeling":[130,192],"\u201cin":[131],"control":[132,165,174,194],"things":[134,176],"your":[136],"life\u201d":[137],"(Table)":[138],"more":[140],"initiate.":[143],"In":[144],"interviews,":[145],"many":[146],"initiates":[148],"expressed":[149],"hopefulness":[150],"a":[152],"desire":[153],"actively":[155],"respond":[156],"their":[158,166,171,178,181],"illness.":[159],"While":[160],"none":[161],"believed":[162],"they":[163],"could":[164],"illness,":[167],"some":[168],"attributed":[170,185],"sense":[172],"over":[175],"relationship":[179],"oncologist,":[182],"others":[184],"it":[186],"informational":[188],"networks.":[189],"Conclusions:":[190],"A":[191],"absence":[196],"depressive":[198],"symptoms":[199],"may":[200],"be":[201],"Further":[210],"exploration":[211],"qualitative":[213],"data":[214],"documenting":[215],"dynamics":[217],"decision-making":[220],"is":[221],"needed.":[222],"[Table:":[223],"see":[224],"text]":[225]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}