{"id":"https://openalex.org/W1581900580","doi":null,"title":"The Development of a Non-invasive Short Synacthen Test","display_name":"The Development of a Non-invasive Short Synacthen Test","publication_year":2015,"publication_date":"2015-02-05","ids":{"openalex":"https://openalex.org/W1581900580","mag":"1581900580"},"language":"en","primary_location":{"id":"pmh:oai:uilis.unsyiah.ac.id:48742","doi":null,"is_oa":false,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/48742","pdf_url":null,"source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://etheses.whiterose.ac.uk/8737/1/CJ%20Elder%20PhD%20thesis%20final%20version%2011.6.14.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072730314","display_name":"Charlotte Jane Elder","orcid":"https://orcid.org/0000-0003-2390-5593","observed_orcids":["https://orcid.org/0000-0003-2390-5593"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Charlotte Elder","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2390-5593","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5072730314"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acth-stimulation-test","display_name":"ACTH stimulation test","score":0.8159999847412109},{"id":"https://openalex.org/keywords/adrenal-insufficiency","display_name":"adrenal insufficiency","score":0.8830000162124634},{"id":"https://openalex.org/keywords/inhaled-corticosteroids","display_name":"inhaled corticosteroids","score":0.9309999942779541},{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.7360000014305115},{"id":"https://openalex.org/keywords/long-term-corticosteroid-therapy","display_name":"long-term corticosteroid therapy","score":0.7739999890327454},{"id":"https://openalex.org/keywords/cortisol-response","display_name":"cortisol response","score":0.37700000405311584},{"id":"https://openalex.org/keywords/non-invasive-assessment","display_name":"non-invasive assessment","score":0.5569999814033508},{"id":"https://openalex.org/keywords/adrenal-function-testing","display_name":"adrenal function testing","score":0.4869999885559082}],"concepts":[{"id":"https://openalex.org/C2777267654","wikidata":"https://www.wikidata.org/wiki/Q3519023","display_name":"Test (biology)","level":2,"score":0.5322603583335876},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36850136518478394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13423368334770203},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:uilis.unsyiah.ac.id:48742","doi":null,"is_oa":false,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/48742","pdf_url":null,"source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:etheses.whiterose.ac.uk:8737","doi":null,"is_oa":true,"landing_page_url":"http://etheses.whiterose.ac.uk/8737/1/CJ%20Elder%20PhD%20thesis%20final%20version%2011.6.14.pdf","pdf_url":"http://etheses.whiterose.ac.uk/8737/1/CJ%20Elder%20PhD%20thesis%20final%20version%2011.6.14.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:1581900580","doi":null,"is_oa":false,"landing_page_url":"https://etheses.whiterose.ac.uk/8737/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:etheses.whiterose.ac.uk:8737","doi":null,"is_oa":true,"landing_page_url":"http://etheses.whiterose.ac.uk/8737/1/CJ%20Elder%20PhD%20thesis%20final%20version%2011.6.14.pdf","pdf_url":"http://etheses.whiterose.ac.uk/8737/1/CJ%20Elder%20PhD%20thesis%20final%20version%2011.6.14.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1581900580.pdf","grobid_xml":"https://content.openalex.org/works/W1581900580.grobid-xml"},"referenced_works_count":154,"referenced_works":["https://openalex.org/W20194251","https://openalex.org/W123752006","https://openalex.org/W205407915","https://openalex.org/W1570306384","https://openalex.org/W1573097114","https://openalex.org/W1576256721","https://openalex.org/W1594418888","https://openalex.org/W1598641519","https://openalex.org/W1908148174","https://openalex.org/W1910488559","https://openalex.org/W1933773871","https://openalex.org/W1965085603","https://openalex.org/W1965584408","https://openalex.org/W1966700213","https://openalex.org/W1967212605","https://openalex.org/W1969667990","https://openalex.org/W1972542847","https://openalex.org/W1972957991","https://openalex.org/W1973617860","https://openalex.org/W1975472022","https://openalex.org/W1975932764","https://openalex.org/W1976008242","https://openalex.org/W1985039241","https://openalex.org/W1985598505","https://openalex.org/W1986763093","https://openalex.org/W1988024075","https://openalex.org/W1989204005","https://openalex.org/W1990090404","https://openalex.org/W1990865193","https://openalex.org/W1990995386","https://openalex.org/W1991528238","https://openalex.org/W1992212028","https://openalex.org/W1993429674","https://openalex.org/W1995236140","https://openalex.org/W1996249229","https://openalex.org/W1997133889","https://openalex.org/W1998400177","https://openalex.org/W1999156064","https://openalex.org/W2001320959","https://openalex.org/W2011520626","https://openalex.org/W2012617534","https://openalex.org/W2013137850","https://openalex.org/W2016823795","https://openalex.org/W2018718803","https://openalex.org/W2018937175","https://openalex.org/W2020716977","https://openalex.org/W2023306095","https://openalex.org/W2026730238","https://openalex.org/W2028709971","https://openalex.org/W2029430817","https://openalex.org/W2033047892","https://openalex.org/W2033567018","https://openalex.org/W2033968662","https://openalex.org/W2034425710","https://openalex.org/W2034929152","https://openalex.org/W2036659497","https://openalex.org/W2039022629","https://openalex.org/W2040206301","https://openalex.org/W2043145107","https://openalex.org/W2046171925","https://openalex.org/W2046192619","https://openalex.org/W2047603891","https://openalex.org/W2050248426","https://openalex.org/W2052526822","https://openalex.org/W2052646125","https://openalex.org/W2053276613","https://openalex.org/W2053944183","https://openalex.org/W2055770319","https://openalex.org/W2057881388","https://openalex.org/W2058190782","https://openalex.org/W2060004264","https://openalex.org/W2061145867","https://openalex.org/W2061268835","https://openalex.org/W2062000903","https://openalex.org/W2062349991","https://openalex.org/W2063915040","https://openalex.org/W2066311937","https://openalex.org/W2066830667","https://openalex.org/W2067664488","https://openalex.org/W2070028366","https://openalex.org/W2072627503","https://openalex.org/W2073388455","https://openalex.org/W2073862919","https://openalex.org/W2077514608","https://openalex.org/W2078447609","https://openalex.org/W2078472861","https://openalex.org/W2079068921","https://openalex.org/W2079612728","https://openalex.org/W2082466693","https://openalex.org/W2085723445","https://openalex.org/W2085750098","https://openalex.org/W2085964188","https://openalex.org/W2086621727","https://openalex.org/W2088317807","https://openalex.org/W2089106756","https://openalex.org/W2089138800","https://openalex.org/W2092105190","https://openalex.org/W2092115006","https://openalex.org/W2093158044","https://openalex.org/W2094437990","https://openalex.org/W2098613051","https://openalex.org/W2101050711","https://openalex.org/W2101857442","https://openalex.org/W2102788189","https://openalex.org/W2105589323","https://openalex.org/W2107137470","https://openalex.org/W2108449402","https://openalex.org/W2108686588","https://openalex.org/W2109805160","https://openalex.org/W2110535212","https://openalex.org/W2112927115","https://openalex.org/W2113592050","https://openalex.org/W2114299877","https://openalex.org/W2115261152","https://openalex.org/W2117681278","https://openalex.org/W2117812057","https://openalex.org/W2120837287","https://openalex.org/W2130197029","https://openalex.org/W2131035808","https://openalex.org/W2131123911","https://openalex.org/W2131474586","https://openalex.org/W2131830610","https://openalex.org/W2133301528","https://openalex.org/W2133587128","https://openalex.org/W2133949387","https://openalex.org/W2134040761","https://openalex.org/W2134062936","https://openalex.org/W2136840435","https://openalex.org/W2138622268","https://openalex.org/W2141061065","https://openalex.org/W2142356382","https://openalex.org/W2142802859","https://openalex.org/W2144398696","https://openalex.org/W2144683051","https://openalex.org/W2145793623","https://openalex.org/W2146784485","https://openalex.org/W2148614804","https://openalex.org/W2149145601","https://openalex.org/W2150478567","https://openalex.org/W2151717609","https://openalex.org/W2152306782","https://openalex.org/W2153224824","https://openalex.org/W2156112012","https://openalex.org/W2158272177","https://openalex.org/W2158554253","https://openalex.org/W2161430958","https://openalex.org/W2165095884","https://openalex.org/W2167823111","https://openalex.org/W2169548184","https://openalex.org/W2169732258","https://openalex.org/W2171246100","https://openalex.org/W2314231067","https://openalex.org/W2320349682","https://openalex.org/W2324005179"],"related_works":["https://openalex.org/W2553258748","https://openalex.org/W4387982058","https://openalex.org/W7147739347","https://openalex.org/W3124601839","https://openalex.org/W3047260109","https://openalex.org/W2994583092","https://openalex.org/W6969021255","https://openalex.org/W4415700230","https://openalex.org/W2072627503","https://openalex.org/W2023842154"],"abstract_inverted_index":{"Patients":[0],"receiving":[1],"long-term":[2],"corticosteroid":[3],"treatment":[4,35],"may":[5],"develop":[6],"adrenal":[7,114],"insufficiency":[8,69],"(AI)":[9],"with":[10],"failure":[11],"of":[12,36,40,148,171,177],"an":[13],"adequate":[14],"cortisol":[15],"surge":[16],"during":[17],"stress,":[18],"potentially":[19],"resulting":[20],"in":[21,33,151],"serious":[22],"illness":[23],"and":[24],"death.There":[25],"is":[26],"growing":[27],"concern":[28],"about":[29],"inhaled":[30],"corticosteroids,":[31],"used":[32],"the":[34,77],"asthma,":[37],"causing":[38],"AI.List":[39],"abbreviated":[41],"terms":[42],"11\uf062-HSD-2":[43],"-11\uf062-hydroxysteroid":[44],"dehydrogenase":[45],"type":[46],"2":[47,96,106],"Ab":[48],"-antibody":[49],"ACTH":[50,57],"-adrenocorticotropic":[51],"hormone":[52,159,162,166],"ACTH(1-24)":[53],"-Synacthen":[54],"ACTH(1-39)":[55],"-endogenous":[56],"ADR":[58],"-adverse":[59],"drug":[60,150],"reaction":[61],"Ag":[62],"-antigen":[63],"Ag*":[64],"-radiolabelled":[65],"antigen":[66],"AI":[67],"-adrenal":[68],"AIDS":[70],"-acquired":[71],"immunodeficiency":[72],"syndrome":[73],"AUC":[74],"-area":[75],"under":[76],"curve":[78],"AVP":[79],"-arginine":[80],"vasopressin":[81],"BDP":[82],"-beclomethasone":[83],"dipropionate":[84],"BNFc":[85],"-British":[86,109],"National":[87],"Formulary":[88],"for":[89],"Children":[90],"BMI":[91],"-body":[92,102],"mass":[93],"index":[94],"(kg/m":[95],")":[97,107],"BMS":[98],"-biomedical":[99],"Scientist":[100],"BSA":[101],"surface":[103],"area":[104],"(m":[105],"BTS":[108],"Thoracic":[110],"Society":[111],"CAH":[112],"-congenital":[113],"hyperplasia":[115],"cAMP":[116],"-cyclic":[117],"adenosine":[118],"monophosphate":[119],"(second":[120],"messenger)":[121],"CAR":[122],"-cortisol":[123],"awakening":[124],"response":[125],"CBG":[126],"-corticosteroid-binding":[127],"globulin":[128],"CCRF":[129],"-children's":[130],"clinical":[131],"research":[132],"facility":[133],"(based":[134],"at":[135],"Sheffield":[136],"Children's":[137],"Hospital)":[138],"CIAs":[139],"-chemiluminescent":[140],"immunometric":[141],"assays":[142],"CL":[143],"-clearance":[144],"Cmax":[145],"-maximum":[146],"concentration":[147],"a":[149],"plasma":[152],"CNS":[153],"-central":[154],"nervous":[155],"system":[156],"CRH":[157],"-corticotrophin-releasing":[158],"CRH-R1":[160],"-corticotropin-releasing":[161,165],"receptor-1":[163],"CRH-R2":[164],"receptor-2":[167],"CTIMP":[168],"-(clinical":[169],"trial":[170],"investigational":[172],"medicinal":[173],"product)":[174],"CV":[175],"-coefficient":[176],"variation":[178]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}
