{"id":"https://openalex.org/W158079520","doi":null,"title":"Update on the use of nitric oxide as a noninvasive measure of airways inflammation.","display_name":"Update on the use of nitric oxide as a noninvasive measure of airways inflammation.","publication_year":2009,"publication_date":"2009-06-01","ids":{"openalex":"https://openalex.org/W158079520","mag":"158079520","pmid":"https://pubmed.ncbi.nlm.nih.gov/19593964"},"language":"en","primary_location":{"id":"pmid:19593964","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19593964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rhinology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055638942","display_name":"Guy Scadding","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210096640","display_name":"Royal Brompton Hospital","ror":"https://ror.org/00cv4n034","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I4210096640"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Guy Scadding","raw_affiliation_strings":["Department of Allergy and Clinical Immunology, Royal Brompton Hospital, London, United Kingdom. g.scadding@ucl.ac.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Allergy and Clinical Immunology, Royal Brompton Hospital, London, United Kingdom. g.scadding@ucl.ac.uk","institution_ids":["https://openalex.org/I4210096640","https://openalex.org/I45129253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073539318","display_name":"Glenis Kathleen Scadding","orcid":"https://orcid.org/0000-0002-0732-9728","observed_orcids":["https://orcid.org/0000-0002-0732-9728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Glenis K Scadding","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.3219,"has_fulltext":false,"cited_by_count":51,"citation_normalized_percentile":{"value":0.9173996,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"47","issue":"2","first_page":"115","last_page":"20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10984","display_name":"Sinusitis and nasal conditions","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9639999866485596},{"id":"https://openalex.org/keywords/exhaled-nitric-oxide","display_name":"exhaled nitric oxide","score":0.8629999756813049},{"id":"https://openalex.org/keywords/airway-inflammation","display_name":"airway inflammation","score":0.8840000033378601},{"id":"https://openalex.org/keywords/eosinophilic-asthma","display_name":"eosinophilic asthma","score":0.9800000190734863},{"id":"https://openalex.org/keywords/chronic-rhinosinusitis","display_name":"chronic rhinosinusitis","score":0.9290000200271606},{"id":"https://openalex.org/keywords/nasal-polyps","display_name":"nasal polyps","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/primary-ciliary-dyskinesia","display_name":"primary ciliary dyskinesia","score":1.0},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nasal-congestion","display_name":"nasal congestion","score":0.949999988079071},{"id":"https://openalex.org/keywords/upper-and-lower-airways","display_name":"upper and lower airways","score":0.7570000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9343544244766235},{"id":"https://openalex.org/C2778206077","wikidata":"https://www.wikidata.org/wiki/Q1690779","display_name":"Primary ciliary dyskinesia","level":4,"score":0.9259811639785767},{"id":"https://openalex.org/C2781142857","wikidata":"https://www.wikidata.org/wiki/Q5420174","display_name":"Exhaled nitric oxide","level":4,"score":0.8993365168571472},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.8825308084487915},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.673930823802948},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.6085717678070068},{"id":"https://openalex.org/C3019717275","wikidata":"https://www.wikidata.org/wiki/Q183344","display_name":"Chronic rhinosinusitis","level":2,"score":0.5605855584144592},{"id":"https://openalex.org/C2781390199","wikidata":"https://www.wikidata.org/wiki/Q8055111","display_name":"Nasal polyps","level":2,"score":0.5287432670593262},{"id":"https://openalex.org/C2779758542","wikidata":"https://www.wikidata.org/wiki/Q2106364","display_name":"Eosinophilic","level":2,"score":0.46170786023139954},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.44724196195602417},{"id":"https://openalex.org/C2777622882","wikidata":"https://www.wikidata.org/wiki/Q417619","display_name":"Nitric oxide synthase","level":3,"score":0.431916207075119},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.33912065625190735},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3038862943649292},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2636571526527405},{"id":"https://openalex.org/C2779379686","wikidata":"https://www.wikidata.org/wiki/Q32778","display_name":"Bronchiectasis","level":3,"score":0.21491214632987976},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.13833215832710266},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.08332997560501099}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012137","descriptor_name":"Respiratory System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012140","descriptor_name":"Respiratory Tract Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:19593964","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19593964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rhinology","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1305633","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1305633/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"RHINOLOGY , 47 (2) 115 - 120. (2009)","raw_type":"Article"},{"id":"mag:158079520","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19593964","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":68,"referenced_works":["https://openalex.org/W185034569","https://openalex.org/W1567219181","https://openalex.org/W1606584992","https://openalex.org/W1782467633","https://openalex.org/W1973358612","https://openalex.org/W1973404534","https://openalex.org/W1974075256","https://openalex.org/W1974698157","https://openalex.org/W1977194497","https://openalex.org/W1977746111","https://openalex.org/W1978304329","https://openalex.org/W1979034033","https://openalex.org/W1980491720","https://openalex.org/W1985837925","https://openalex.org/W1991869169","https://openalex.org/W1994909860","https://openalex.org/W1995075232","https://openalex.org/W1997081772","https://openalex.org/W1997626407","https://openalex.org/W2003914381","https://openalex.org/W2007452107","https://openalex.org/W2007737411","https://openalex.org/W2009655741","https://openalex.org/W2030856454","https://openalex.org/W2032374099","https://openalex.org/W2038777547","https://openalex.org/W2039281731","https://openalex.org/W2042800674","https://openalex.org/W2045868513","https://openalex.org/W2047561072","https://openalex.org/W2049033509","https://openalex.org/W2049246702","https://openalex.org/W2050700497","https://openalex.org/W2062583221","https://openalex.org/W2065778171","https://openalex.org/W2070457737","https://openalex.org/W2071575222","https://openalex.org/W2073626955","https://openalex.org/W2075172386","https://openalex.org/W2078348184","https://openalex.org/W2081020551","https://openalex.org/W2081078817","https://openalex.org/W2082978209","https://openalex.org/W2085362217","https://openalex.org/W2086881305","https://openalex.org/W2087377712","https://openalex.org/W2089538909","https://openalex.org/W2092145002","https://openalex.org/W2095356659","https://openalex.org/W2100578775","https://openalex.org/W2103535893","https://openalex.org/W2105494428","https://openalex.org/W2115533627","https://openalex.org/W2117363076","https://openalex.org/W2121869188","https://openalex.org/W2135655283","https://openalex.org/W2143570029","https://openalex.org/W2146758613","https://openalex.org/W2152345375","https://openalex.org/W2154830705","https://openalex.org/W2162452275","https://openalex.org/W2164132449","https://openalex.org/W2164557164","https://openalex.org/W2169912768","https://openalex.org/W2170413821","https://openalex.org/W2338868403","https://openalex.org/W2779587116","https://openalex.org/W2993259418"],"related_works":["https://openalex.org/W3185703929","https://openalex.org/W2995891464","https://openalex.org/W2065071225","https://openalex.org/W3202479594","https://openalex.org/W2040144108","https://openalex.org/W2162459294","https://openalex.org/W2411446626","https://openalex.org/W2162207167","https://openalex.org/W2182995617","https://openalex.org/W2064242656"],"abstract_inverted_index":{"Nitric":[0],"oxide":[1,20,36,88,101],"levels":[2],"may":[3,37,48,102],"reflect":[4],"the":[5,10,27,54,72,84,104],"inflammatory":[6],"status":[7],"of":[8,16,31,58,74,86,107],"both":[9,96],"upper":[11,108],"and":[12,29,56,65,92,98,109],"lower":[13,110],"airways.":[14,111],"Measurement":[15],"exhaled":[17],"bronchial":[18,97],"nitric":[19,35,87,100],"is":[21,80],"a":[22,50],"useful,":[23],"non-invasive":[24],"tool":[25,52],"in":[26,43,53,71,89],"diagnosis":[28,55,73],"management":[30,57,106],"eosinophilic":[32],"asthma.":[33],"Nasal":[34],"be":[38,49],"normal,":[39],"raised":[40],"or":[41],"lowered":[42],"disease":[44],"states;":[45],"however":[46],"measurement":[47],"useful":[51],"patients":[59],"with":[60],"chronic":[61],"rhinosinusitis,":[62],"nasal":[63,93,99],"polyps,":[64],"cystic":[66],"fibrosis,":[67],"as":[68,70],"well":[69],"primary":[75],"ciliary":[76],"dyskinesia.":[77],"Further":[78],"research":[79],"aimed":[81],"at":[82],"investigating":[83],"role":[85],"allergic":[90],"rhinitis":[91],"congestion.":[94],"Measuring":[95],"assist":[103],"combined":[105]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}