{"id":"https://openalex.org/W1580239074","doi":null,"title":"Influence of Stress and Cytokinic Profiles on Cognitive Performance in Older Adults","display_name":"Influence of Stress and Cytokinic Profiles on Cognitive Performance in Older Adults","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1580239074","mag":"1580239074"},"language":"en","primary_location":{"id":"pmh:oai:digitalcommons.usf.edu:etd-5407","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.usf.edu/etd/4211","pdf_url":"https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=5407&context=etd","source":{"id":"https://openalex.org/S4377196272","display_name":"Digital Commons - University of South Florida (University of South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2613432","host_organization_name":"University of South Florida","host_organization_lineage":["https://openalex.org/I2613432"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"USF Tampa Graduate Theses and Dissertations","raw_type":"dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=5407&context=etd","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070641004","display_name":"Kerri Sharp Rawson","orcid":"https://orcid.org/0000-0002-1800-4910","observed_orcids":["https://orcid.org/0000-0002-1800-4910"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kerri S. Rawson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1800-4910","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5070641004"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.16279999911785126,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.02239999920129776,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cognitive-aging","display_name":"cognitive aging","score":0.6309999823570251},{"id":"https://openalex.org/keywords/stress","display_name":"stress","score":0.6110000014305115},{"id":"https://openalex.org/keywords/th1-th2-cytokines","display_name":"Th1/Th2 cytokines","score":0.8100000023841858},{"id":"https://openalex.org/keywords/ifn-gamma-il-4-ratio","display_name":"IFN-\u03b3/IL-4 ratio","score":0.8489999771118164},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8669999837875366},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.8429999947547913},{"id":"https://openalex.org/keywords/processing-speed","display_name":"processing speed","score":0.8730000257492065},{"id":"https://openalex.org/keywords/episodic-memory","display_name":"episodic memory","score":0.9990000128746033},{"id":"https://openalex.org/keywords/age-related-cognitive-decline","display_name":"age-related cognitive decline","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C21036866","wikidata":"https://www.wikidata.org/wiki/Q181767","display_name":"Stress (linguistics)","level":2,"score":0.5663242340087891},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.5611281394958496},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4907337427139282},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.456871896982193},{"id":"https://openalex.org/C185711340","wikidata":"https://www.wikidata.org/wiki/Q5347381","display_name":"Effects of sleep deprivation on cognitive performance","level":3,"score":0.4297037124633789},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.38554906845092773},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.32780152559280396},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32456398010253906},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.3226916790008545},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2546977400779724},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.13027912378311157},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:digitalcommons.usf.edu:etd-5407","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.usf.edu/etd/4211","pdf_url":"https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=5407&context=etd","source":{"id":"https://openalex.org/S4377196272","display_name":"Digital Commons - University of South Florida (University of South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2613432","host_organization_name":"University of South Florida","host_organization_lineage":["https://openalex.org/I2613432"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"USF Tampa Graduate Theses and Dissertations","raw_type":"dissertation"},{"id":"pmh:oai:scholarcommons.usf.edu:etd-5407","doi":null,"is_oa":false,"landing_page_url":"https://scholarcommons.usf.edu/etd/4211","pdf_url":null,"source":{"id":"https://openalex.org/S4377196272","display_name":"Digital Commons - University of South Florida (University of South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2613432","host_organization_name":"University of South Florida","host_organization_lineage":["https://openalex.org/I2613432"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Graduate Theses and Dissertations","raw_type":"text"},{"id":"mag:1580239074","doi":null,"is_oa":false,"landing_page_url":"https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=5407&context=etd","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:digitalcommons.usf.edu:etd-5407","doi":null,"is_oa":true,"landing_page_url":"https://digitalcommons.usf.edu/etd/4211","pdf_url":"https://digitalcommons.usf.edu/cgi/viewcontent.cgi?article=5407&context=etd","source":{"id":"https://openalex.org/S4377196272","display_name":"Digital Commons - University of South Florida (University of South Florida)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2613432","host_organization_name":"University of South Florida","host_organization_lineage":["https://openalex.org/I2613432"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"USF Tampa Graduate Theses and Dissertations","raw_type":"dissertation"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1580239074.pdf","grobid_xml":"https://content.openalex.org/works/W1580239074.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1896762683","https://openalex.org/W1920894533","https://openalex.org/W1963629744","https://openalex.org/W1966639644","https://openalex.org/W1969727768","https://openalex.org/W1971382923","https://openalex.org/W1978765950","https://openalex.org/W1983182638","https://openalex.org/W1986939668","https://openalex.org/W1987912134","https://openalex.org/W1988848925","https://openalex.org/W1989321304","https://openalex.org/W1991680271","https://openalex.org/W1994631256","https://openalex.org/W1996299251","https://openalex.org/W2000555003","https://openalex.org/W2021668133","https://openalex.org/W2025077961","https://openalex.org/W2030298463","https://openalex.org/W2035121127","https://openalex.org/W2037959652","https://openalex.org/W2039132151","https://openalex.org/W2039300784","https://openalex.org/W2041337739","https://openalex.org/W2044106385","https://openalex.org/W2046601986","https://openalex.org/W2052821326","https://openalex.org/W2058044289","https://openalex.org/W2066609350","https://openalex.org/W2067919562","https://openalex.org/W2069272538","https://openalex.org/W2069895662","https://openalex.org/W2070336685","https://openalex.org/W2074949522","https://openalex.org/W2076219964","https://openalex.org/W2076362385","https://openalex.org/W2079075941","https://openalex.org/W2082546380","https://openalex.org/W2083283628","https://openalex.org/W2087461241","https://openalex.org/W2104417544","https://openalex.org/W2107337543","https://openalex.org/W2107759391","https://openalex.org/W2108601142","https://openalex.org/W2111024109","https://openalex.org/W2112818206","https://openalex.org/W2132539548","https://openalex.org/W2143047222","https://openalex.org/W2162066293","https://openalex.org/W2163857054","https://openalex.org/W2167852162","https://openalex.org/W2168610467","https://openalex.org/W2417848539","https://openalex.org/W2481643597","https://openalex.org/W2924822559"],"related_works":["https://openalex.org/W4390081087","https://openalex.org/W4389068348","https://openalex.org/W2108601142","https://openalex.org/W4200431796","https://openalex.org/W1975370782","https://openalex.org/W4394600669","https://openalex.org/W2937904431","https://openalex.org/W4200058284","https://openalex.org/W1514349057","https://openalex.org/W278682665"],"abstract_inverted_index":{"ABSTRACT":[0],"With":[1],"aging,":[2],"changes":[3],"in":[4,41,60],"the":[5,12,23,42,64,93,160,171,215],"immune":[6,24,36,45,184,209],"system,":[7,25],"makes":[8],"cognitive":[9,75,78,116,144,181,201,231],"performance,":[10,202],"and":[11,34,44,74,88,95,118,121,130,152,164,180,199],"prevalence":[13,94],"of":[14,56,63,97,115,150,193],"stressors":[15,98],"can":[16,47],"lead":[17,99],"to":[18,100,225],"poorer":[19,101],"overall":[20],"functioning.":[21,76],"Within":[22],"a":[26,81,175,190,220,227],"balance":[27],"should":[28],"exist":[29],"between":[30,162,178,195],"cytokines":[31,59,73],"regulating":[32],"Th1":[33,57,129,163,188],"Th2":[35,71,131,165],"responses;":[37],"however,":[38],"age-related":[39],"declines":[40],"endocrine":[43],"systems":[46],"disrupt":[48],"this":[49,204],"equilibrium.":[50],"Several":[51],"studies":[52,68],"report":[53],"higher":[54],"levels":[55],"associated":[58,72,141],"inflammatory":[61],"conditions":[62],"brain,":[65],"whereas":[66,203],"fewer":[67],"remark":[69],"on":[70,128,230],"Declining":[77],"abilities":[79],"are":[80],"common":[82],"concern":[83],"that":[84,136,219],"accompanies":[85],"advancing":[86],"age":[87,138],"some":[89],"research":[90],"has":[91],"suggested":[92],"impact":[96],"performance.":[102,182,232],"Participants":[103],"included":[104],"92":[105],"older":[106],"adults":[107],"(M":[108],"=":[109],"74.05":[110],"years)":[111],"who":[112,124],"completed":[113],"tests":[114],"performance":[117],"stress":[119,179,197,224],"measures,":[120],"41":[122],"persons":[123],"had":[125],"valid":[126],"data":[127],"cytokines.":[132],"The":[133],"results":[134],"indicated":[135],"increasing":[137],"is":[139,174],"significantly":[140],"with":[142],"several":[143],"domains":[145],"including":[146],"executive":[147],"functioning,":[148],"speed":[149],"processing,":[151],"episodic":[153],"memory.":[154],"As":[155],"hypothesized,":[156],"moderation":[157],"analysis":[158],"revealed":[159],"relationship":[161],"cytokinic":[166],"profiles,":[167],"as":[168],"denoted":[169],"by":[170],"IFN-\u03b3/IL-4":[172],"ratio,":[173],"significant":[176,191],"moderator":[177],"Specifically,":[183],"profiles":[185,210],"skewed":[186,211],"towards":[187,212],"predict":[189],"amount":[192],"variation":[194],"high":[196],"scores":[198],"low":[200],"was":[205],"not":[206],"found":[207],"for":[208],"Th2.":[213],"Overall,":[214],"current":[216],"study":[217],"suggests":[218],"pro-inflammatory":[221],"state":[222],"permits":[223],"exert":[226],"negative":[228],"influence":[229]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}