{"id":"https://openalex.org/W1578656","doi":"https://doi.org/10.1007/978-1-4684-5886-2_2","title":"Immune Responses and the Central Nervous System","display_name":"Immune Responses and the Central Nervous System","publication_year":1992,"publication_date":"1992-01-01","ids":{"openalex":"https://openalex.org/W1578656","doi":"https://doi.org/10.1007/978-1-4684-5886-2_2","mag":"1578656"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4684-5886-2_2","doi":"https://doi.org/10.1007/978-1-4684-5886-2_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4684-5886-2_2","pdf_url":null,"source":{"id":"https://openalex.org/S4210223329","display_name":"Infectious agents and pathogenesis","issn_l":"1075-1289","issn":["1075-1289"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious Agents and Pathogenesis","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W649484648","display_name":"Neuropathogenic Viruses and Immunity"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058209103","display_name":"William R. Tyor","orcid":"https://orcid.org/0000-0002-0661-4842","observed_orcids":["https://orcid.org/0000-0002-0661-4842"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William R. Tyor","raw_affiliation_strings":["Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002311826","display_name":"Richard T. Johnson","orcid":"https://orcid.org/0000-0002-4962-5285","observed_orcids":["https://orcid.org/0000-0002-4962-5285"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard T. Johnson","raw_affiliation_strings":["Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, 21205, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4335,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.74827586,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"15","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.5253999829292297,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.5253999829292297,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.14259999990463257,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.05559999868273735,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"central nervous system","score":0.875},{"id":"https://openalex.org/keywords/immune-privilege","display_name":"immune privilege","score":0.6380000114440918},{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9940000176429749},{"id":"https://openalex.org/keywords/viral-clearance","display_name":"viral clearance","score":0.5889999866485596},{"id":"https://openalex.org/keywords/neurovirus-infection","display_name":"neurovirus infection","score":0.45500001311302185},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.802186131477356},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.7704107761383057},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5926265120506287},{"id":"https://openalex.org/C181152851","wikidata":"https://www.wikidata.org/wiki/Q712604","display_name":"Lymphatic system","level":2,"score":0.5554915070533752},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5473031401634216},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.48118287324905396},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4225904941558838},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2994840145111084}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4684-5886-2_2","doi":"https://doi.org/10.1007/978-1-4684-5886-2_2","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4684-5886-2_2","pdf_url":null,"source":{"id":"https://openalex.org/S4210223329","display_name":"Infectious agents and pathogenesis","issn_l":"1075-1289","issn":["1075-1289"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infectious Agents and Pathogenesis","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.5600000023841858,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W128515132","https://openalex.org/W425307498","https://openalex.org/W568493077","https://openalex.org/W657381594","https://openalex.org/W1488452721","https://openalex.org/W1493437824","https://openalex.org/W1517159675","https://openalex.org/W1568750314","https://openalex.org/W1597379402","https://openalex.org/W1600606776","https://openalex.org/W1771396631","https://openalex.org/W1830057395","https://openalex.org/W1830778808","https://openalex.org/W1896422958","https://openalex.org/W1902258135","https://openalex.org/W1965829947","https://openalex.org/W1970144442","https://openalex.org/W1974129677","https://openalex.org/W1984952188","https://openalex.org/W1990137584","https://openalex.org/W1998115736","https://openalex.org/W2001758550","https://openalex.org/W2018766773","https://openalex.org/W2021136928","https://openalex.org/W2025001062","https://openalex.org/W2036307954","https://openalex.org/W2037405613","https://openalex.org/W2039904633","https://openalex.org/W2047655762","https://openalex.org/W2056351034","https://openalex.org/W2067004325","https://openalex.org/W2067042506","https://openalex.org/W2070777934","https://openalex.org/W2074921365","https://openalex.org/W2076407459","https://openalex.org/W2080599448","https://openalex.org/W2125973352","https://openalex.org/W2154365842","https://openalex.org/W2163882251","https://openalex.org/W2261565571","https://openalex.org/W2304531976","https://openalex.org/W2403000283","https://openalex.org/W2409105505","https://openalex.org/W2419053233","https://openalex.org/W2428575676","https://openalex.org/W2585599833","https://openalex.org/W4232576781","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2264944826","https://openalex.org/W182761584","https://openalex.org/W2506406328","https://openalex.org/W2406106130","https://openalex.org/W4212839086","https://openalex.org/W3133013532","https://openalex.org/W2081025027","https://openalex.org/W4223488955","https://openalex.org/W2074736197","https://openalex.org/W2407370556"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}
