{"id":"https://openalex.org/W157832052","doi":null,"title":"Do delayed childbearers face increased risks of adverse pregnancy outcomes after the first birth?","display_name":"Do delayed childbearers face increased risks of adverse pregnancy outcomes after the first birth?","publication_year":1993,"publication_date":"1993-04-01","ids":{"openalex":"https://openalex.org/W157832052","mag":"157832052","pmid":"https://pubmed.ncbi.nlm.nih.gov/8459958"},"language":"en","primary_location":{"id":"pmid:8459958","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8459958","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085361966","display_name":"Sven Cnattingius","orcid":"https://orcid.org/0000-0002-0805-8093","observed_orcids":["https://orcid.org/0000-0002-0805-8093"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S Cnattingius","raw_affiliation_strings":["Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109063321","display_name":"H. Berendes","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H W Berendes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5013262825","display_name":"Michele R. Forman","orcid":"https://orcid.org/0000-0002-3060-6068","observed_orcids":["https://orcid.org/0000-0002-3060-6068"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M R Forman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1304,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.75026123,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"81","issue":"4","first_page":"512","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10453","display_name":"Maternal and Perinatal Health Interventions","score":0.9653000235557556,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12741","display_name":"Maternal and Neonatal Healthcare","score":0.011300000362098217,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11732","display_name":"Assisted Reproductive Technology and Twin Pregnancy","score":0.004699999932199717,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/maternal-age","display_name":"maternal age","score":0.6340000033378601},{"id":"https://openalex.org/keywords/delayed-childbearing","display_name":"delayed childbearing","score":0.9340000152587891},{"id":"https://openalex.org/keywords/adverse-pregnancy-outcomes","display_name":"adverse pregnancy outcomes","score":0.7910000085830688},{"id":"https://openalex.org/keywords/second-birth","display_name":"second birth","score":0.4779999852180481},{"id":"https://openalex.org/keywords/late-fetal-death","display_name":"late fetal death","score":0.8949999809265137},{"id":"https://openalex.org/keywords/early-neonatal-death","display_name":"early neonatal death","score":0.9419999718666077},{"id":"https://openalex.org/keywords/low-birth-weight","display_name":"low birth weight","score":0.996999979019165},{"id":"https://openalex.org/keywords/preterm-birth","display_name":"preterm birth","score":1.0},{"id":"https://openalex.org/keywords/advanced-maternal-age","display_name":"advanced maternal age","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.920799970626831},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.7673864364624023},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.7434045076370239},{"id":"https://openalex.org/C2779083892","wikidata":"https://www.wikidata.org/wiki/Q6692979","display_name":"Low birth weight","level":3,"score":0.5664532780647278},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5538698434829712},{"id":"https://openalex.org/C66322754","wikidata":"https://www.wikidata.org/wiki/Q4128476","display_name":"Birth weight","level":3,"score":0.5492666363716125},{"id":"https://openalex.org/C2778279030","wikidata":"https://www.wikidata.org/wiki/Q1543380","display_name":"Live birth","level":3,"score":0.4697680175304413},{"id":"https://openalex.org/C2776344615","wikidata":"https://www.wikidata.org/wiki/Q625506","display_name":"Premature birth","level":4,"score":0.46842682361602783},{"id":"https://openalex.org/C77350462","wikidata":"https://www.wikidata.org/wiki/Q1125472","display_name":"Confounding","level":2,"score":0.455221563577652},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.2921186089515686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.07580214738845825},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005313","descriptor_name":"Fetal Death","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007226","descriptor_name":"Infant Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007230","descriptor_name":"Infant, Low Birth Weight","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007752","descriptor_name":"Obstetric Labor, Premature","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008423","descriptor_name":"Maternal Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010298","descriptor_name":"Parity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011248","descriptor_name":"Pregnancy Complications","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011256","descriptor_name":"Pregnancy Outcome","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013548","descriptor_name":"Sweden","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:8459958","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8459958","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Obstetrics and gynecology","raw_type":"Journal Article"},{"id":"mag:157832052","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8459958","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.8399999737739563,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4238407324","https://openalex.org/W2319008072","https://openalex.org/W2000940073","https://openalex.org/W2012519050","https://openalex.org/W167278313","https://openalex.org/W4323915753","https://openalex.org/W18032515","https://openalex.org/W2119629969","https://openalex.org/W7006732002","https://openalex.org/W1980453489"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"whether":[3],"the":[4,12,17,25,33,47,60,66,70,77,126,148,169,193,210,220,232,241],"age-related":[5,233,268],"risk":[6,71],"of":[7,27,62,72,85,113,141,164,176,187,206,256,296],"adverse":[8,29,73,86,226,257],"pregnancy":[9,30,74,87,227,243,258],"outcomes":[10,75,88,259],"in":[11,16,32,76,92,95,229,260,270,278],"first":[13,34,67,78,93,127,149,170,194,211,251,261,292],"birth":[14,35,68,171,189,208,288],"persisted":[15],"second":[18,80,96,131,153,180,198,215,230,264,294],"birth,":[19],"before":[20],"and":[21,36,79,119,174,197,202,214,274,286,293],"after":[22],"adjusting":[23],"for":[24,37,125,130,147,152,168,179,192,209,240,284,291],"influence":[26],"an":[28,177,225],"outcome":[31,228],"other":[38],"possible":[39],"confounders.":[40],"METHODS:":[41],"Prospectively":[42],"collected":[43],"longitudinal":[44],"data":[45],"from":[46],"Swedish":[48],"Medical":[49],"Birth":[50],"Registry":[51],"(n":[52],"=":[53],"210,735":[54],"women)":[55],"were":[56,89,289],"analyzed":[57],"to":[58,223],"contrast":[59],"effects":[61],"maternal":[63],"age":[64],"at":[65,249],"on":[69],"successive":[81],"births.":[82,97,154,262],"RESULTS:":[83],"Rates":[84],"substantially":[90],"higher":[91,109,139,162,185,204],"than":[94],"Compared":[98],"with":[99,238],"women":[100,103,133],"aged":[101,104,134,247],"20-24,":[102],"30-34":[105],"years":[106],"had":[107,136,159],"significantly":[108,138,161],"odds":[110],"ratios":[111],"(ORs)":[112],"late":[114,142,271],"fetal":[115,143,272],"death":[116,122,144,167,273],"(OR":[117,123,145,172,182,195,200,212,217],"1.4)":[118,124,213],"early":[120,165,279],"neonatal":[121,166,280],"but":[128,150],"not":[129,151,236],"births;":[132],"35+":[135],"a":[137,160,184,203,275],"OR":[140,163,186,205],"2.2)":[146],"Women":[155,246],"over":[156],"35":[157],"also":[158],"2.8)":[173],"less":[175],"increase":[178,269,277],"births":[181,199,216,252,265,295],"1.8),":[183],"low":[188],"weight":[190],"(LBW)":[191],"1.5)":[196],"1.6),":[201],"preterm":[207,287],"1.7).":[218],"Despite":[219],"strong":[221],"tendency":[222],"repeat":[224],"births,":[231],"ORs":[234],"did":[235],"change":[237],"adjustment":[239],"previous":[242],"outcome.":[244],"CONCLUSION:":[245],"30+":[248],"their":[250],"have":[253],"increased":[254],"risks":[255,283],"However,":[263],"showed":[266],"no":[267],"smaller":[276],"death.":[281],"Increased":[282],"LBW":[285],"similar":[290],"delayed":[297],"childbearers.":[298]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}