{"id":"https://openalex.org/W1578200775","doi":"https://doi.org/10.2106/00004623-198769090-00008","title":"Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells","display_name":"Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells","publication_year":1987,"publication_date":"1987-12-01","ids":{"openalex":"https://openalex.org/W1578200775","doi":"https://doi.org/10.2106/00004623-198769090-00008","mag":"1578200775","pmid":"https://pubmed.ncbi.nlm.nih.gov/3126189"},"language":"en","primary_location":{"id":"doi:10.2106/00004623-198769090-00008","doi":"https://doi.org/10.2106/00004623-198769090-00008","is_oa":false,"landing_page_url":"https://doi.org/10.2106/00004623-198769090-00008","pdf_url":null,"source":{"id":"https://openalex.org/S128848949","display_name":"Journal of Bone and Joint Surgery","issn_l":"0021-9355","issn":["0021-9355","1058-2436","1535-1386"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Bone & Joint Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002102879","display_name":"Dane K. Wukich","orcid":"https://orcid.org/0000-0002-3637-6208","observed_orcids":["https://orcid.org/0000-0002-3637-6208"]},"institutions":[{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D K Wukich","raw_affiliation_strings":["Orthopaedic Surgery Service, Walter Reed Army Medical Center, Washington, D.C. 20307-5001"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedic Surgery Service, Walter Reed Army Medical Center, Washington, D.C. 20307-5001","institution_ids":["https://openalex.org/I2800363604"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109845874","display_name":"S H Abreu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S H Abreu","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112036548","display_name":"John J Callaghan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J J Callaghan","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068782465","display_name":"Douglas Van Nostrand","orcid":"https://orcid.org/0000-0002-6491-4560","observed_orcids":["https://orcid.org/0000-0002-6491-4560"]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D Van Nostrand","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062975419","display_name":"CARLTON G. SAVORY","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C G Savory","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108478126","display_name":"Douglas F. Eggli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D F Eggli","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113655958","display_name":"Jairo E. Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I92664306","display_name":"Walter Reed Army Institute of Research","ror":"https://ror.org/0145znz58","country_code":"US","type":"government","lineage":["https://openalex.org/I106965489","https://openalex.org/I1304082316","https://openalex.org/I1330347796","https://openalex.org/I2802581893","https://openalex.org/I92664306"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J E Garcia","raw_affiliation_strings":["Walter Reed Army Institute of Research"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Institute of Research","institution_ids":["https://openalex.org/I92664306"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109838943","display_name":"B. Hudson Berrey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800363604","display_name":"Walter Reed National Military Medical Center","ror":"https://ror.org/025cem651","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330347796","https://openalex.org/I2800250139","https://openalex.org/I2800363604","https://openalex.org/I2800386880"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B H Berrey","raw_affiliation_strings":["Walter Reed Army Medical Center , Washington, DC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Walter Reed Army Medical Center , Washington, DC, USA","institution_ids":["https://openalex.org/I2800363604"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":4.401,"has_fulltext":false,"cited_by_count":77,"citation_normalized_percentile":{"value":0.93411245,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"69","issue":"9","first_page":"1353","last_page":"1360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indium-111-white-blood-cell-scintigraphy","display_name":"indium-111 white blood cell scintigraphy","score":0.9340000152587891},{"id":"https://openalex.org/keywords/osteomyelitis","display_name":"osteomyelitis","score":0.8090000152587891},{"id":"https://openalex.org/keywords/chronic-osteomyelitis","display_name":"chronic osteomyelitis","score":0.9210000038146973},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7699999809265137},{"id":"https://openalex.org/keywords/false-positive-results","display_name":"false positives","score":0.6930000185966492},{"id":"https://openalex.org/keywords/false-negative-results","display_name":"false-negative results","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6538227200508118},{"id":"https://openalex.org/C2779902710","wikidata":"https://www.wikidata.org/wiki/Q1130465","display_name":"Scintigraphy","level":2,"score":0.5312739610671997},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4284456670284271},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.40021610260009766}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001424","descriptor_name":"Bacterial Infections","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D005188","descriptor_name":"False Negative Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005189","descriptor_name":"False Positive Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006912","descriptor_name":"Hydroxyquinolines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007205","descriptor_name":"Indium Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007962","descriptor_name":"Leukocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009942","descriptor_name":"Organometallic Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010019","descriptor_name":"Osteomyelitis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D011300","descriptor_name":"Preoperative Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011877","descriptor_name":"Radionuclide Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013669","descriptor_name":"Technetium Tc 99m Medronate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015125","descriptor_name":"Oxyquinoline","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2106/00004623-198769090-00008","doi":"https://doi.org/10.2106/00004623-198769090-00008","is_oa":false,"landing_page_url":"https://doi.org/10.2106/00004623-198769090-00008","pdf_url":null,"source":{"id":"https://openalex.org/S128848949","display_name":"Journal of Bone and Joint Surgery","issn_l":"0021-9355","issn":["0021-9355","1058-2436","1535-1386"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Bone & Joint Surgery","raw_type":"journal-article"},{"id":"pmid:3126189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3126189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of bone and joint surgery. American volume","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2063331732","https://openalex.org/W2398034201","https://openalex.org/W2037584609","https://openalex.org/W2170932912","https://openalex.org/W2256965313","https://openalex.org/W2153087194","https://openalex.org/W2000576335","https://openalex.org/W2089171072","https://openalex.org/W2409695672","https://openalex.org/W1554047529"],"abstract_inverted_index":{"Scintigraphy":[0],"with":[1,47,53,177,217],"indium-labeled":[2,178],"white":[3,56,179],"blood":[4,57,180],"cells":[5,58,181],"has":[6],"been":[7],"reported":[8],"to":[9,141],"be":[10,142,197,208],"sensitive":[11],"and":[12,43,51,95,122,169],"specific":[13,188],"in":[14,73,120,166,172,189,215],"the":[15,21,26,74,79,92,145,212,218],"diagnosis":[16,136],"of":[17,20,28,78,83,86,89,111,115,124,130,137],"low-grade":[18],"sepsis":[19],"musculoskeletal":[22],"system.":[23],"We":[24],"reviewed":[25],"records":[27],"fifty":[29],"patients":[30,101,132,165,171],"who":[31,44,66],"had":[32,117,140],"suspected":[33,36],"osteomyelitis":[34,139,202],"or":[35],"infection":[37],"about":[38],"a":[39,87,118,135,193],"total":[40],"joint":[41],"prosthesis":[42,119],"underwent":[45],"scintigraphy":[46,52,176],"technetium-99m":[48],"methylene":[49],"diphosphonate":[50],"indium-111":[54],"oxine-labeled":[55],"before":[59],"an":[60],"open":[61],"surgical":[62],"procedure.":[63],"Any":[64],"patient":[65],"received":[67],"preoperative":[68],"antibiotics":[69],"was":[70,109,128,150],"not":[71,187,204],"included":[72],"study.":[75],"For":[76],"all":[77],"patients,":[80,113],"gram-stain":[81],"examination":[82,97],"smears,":[84],"evaluation":[85],"culture":[88],"material":[90],"from":[91],"operative":[93],"site,":[94],"histological":[96],"were":[98,102,160],"done.":[99],"The":[100],"divided":[103],"into":[104],"two":[105],"groups.":[106],"Group":[107,126,156,167,173],"I":[108],"composed":[110,129],"twenty-four":[112],"each":[114],"whom":[116,134],"place":[121],"complained":[123],"pain.":[125],"II":[127,168],"twenty-six":[131],"for":[133],"chronic":[138,191],"considered.":[143],"With":[144],"indium":[146,213],"scans":[147],"alone,":[148],"there":[149,159],"only":[151],"one":[152],"false-negative":[153],"result":[154],"(in":[155],"II),":[157],"but":[158],"eighteen":[161],"false-positive":[162],"results":[163],"(eight":[164],"ten":[170],"I).":[174],"Although":[175],"is":[182,186,203],"quite":[183],"sensitive,":[184],"it":[185],"detecting":[190],"osteomyelitis;":[192],"negative":[194],"scan":[195,214],"should":[196],"considered":[198],"highly":[199],"suggestive":[200],"that":[201],"present.":[205],"Specificity":[206],"can":[207],"increased":[209],"by":[210],"interpreting":[211],"conjunction":[216],"technetium":[219],"scan.":[220]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}