{"id":"https://openalex.org/W1576721801","doi":null,"title":"The Role of AMPK in Viral Infection","display_name":"The Role of AMPK in Viral Infection","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W1576721801","mag":"1576721801"},"language":"en","primary_location":{"id":"pmh:oai:repository.upenn.edu:20.500.14332/32766","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/handle/20.500.14332/32766","pdf_url":null,"source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":"Dissertation/Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024461338","display_name":"Theresa S. Moser","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Theresa S. Moser","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5024461338"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11767","display_name":"Poxvirus research and outbreaks","score":0.7588000297546387,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11767","display_name":"Poxvirus research and outbreaks","score":0.7588000297546387,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.05009999871253967,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.03319999948143959,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ampk","display_name":"AMPK","score":0.9980000257492065},{"id":"https://openalex.org/keywords/viral-infection","display_name":"viral infection","score":0.7699999809265137},{"id":"https://openalex.org/keywords/vaccinia-virus","display_name":"vaccinia virus","score":0.8560000061988831},{"id":"https://openalex.org/keywords/poxvirus","display_name":"poxvirus","score":0.7039999961853027},{"id":"https://openalex.org/keywords/macropinocytosis","display_name":"macropinocytosis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/actin-dynamics","display_name":"actin dynamics","score":0.8180000185966492},{"id":"https://openalex.org/keywords/lamellipodia","display_name":"lamellipodia","score":0.8209999799728394},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.972000002861023},{"id":"https://openalex.org/keywords/rift-valley-fever-virus","display_name":"Rift Valley fever virus","score":0.7170000076293945},{"id":"https://openalex.org/keywords/bunyaviridae","display_name":"Bunyaviridae","score":0.7670000195503235},{"id":"https://openalex.org/keywords/fatty-acid-synthesis","display_name":"fatty acid synthesis","score":0.8330000042915344},{"id":"https://openalex.org/keywords/acetyl-coa-carboxylase","display_name":"acetyl-CoA carboxylase","score":0.9769999980926514},{"id":"https://openalex.org/keywords/liver-kinase-b1","display_name":"LKB1","score":0.9390000104904175},{"id":"https://openalex.org/keywords/sindbis-virus","display_name":"Sindbis virus","score":0.9179999828338623},{"id":"https://openalex.org/keywords/vesicular-stomatitis-virus","display_name":"vesicular stomatitis virus","score":0.9279999732971191},{"id":"https://openalex.org/keywords/rna-viruses","display_name":"RNA viruses","score":0.5550000071525574},{"id":"https://openalex.org/keywords/virus-host-interactions","display_name":"host-virus interaction","score":0.7429999709129333},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.625},{"id":"https://openalex.org/keywords/antiviral-agents","display_name":"antiviral agents","score":0.7960000038146973},{"id":"https://openalex.org/keywords/rnai-screen","display_name":"RNAi screen","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.494048148393631},{"id":"https://openalex.org/C2780124434","wikidata":"https://www.wikidata.org/wiki/Q12357464","display_name":"AMPK","level":4,"score":0.4653606712818146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38806620240211487},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3340802788734436},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21006062626838684},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.11816525459289551},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.0},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:repository.upenn.edu:20.500.14332/32766","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/handle/20.500.14332/32766","pdf_url":null,"source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":"Dissertation/Thesis"},{"id":"pmh:oai:repository.upenn.edu:dissertations-10639","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/dissertations/AAI3485716","pdf_url":null,"source":{"id":"https://openalex.org/S4377196331","display_name":"Scholarly Commons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dissertations available from ProQuest","raw_type":"text"},{"id":"pmh:oai:repository.upenn.edu:edissertations-1537","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/edissertations/975","pdf_url":null,"source":{"id":"https://openalex.org/S4377196331","display_name":"Scholarly Commons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Publicly Accessible Penn Dissertations","raw_type":"text"},{"id":"mag:1576721801","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/cgi/viewcontent.cgi?article=10639&context=dissertations","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":314,"referenced_works":["https://openalex.org/W117739986","https://openalex.org/W177243190","https://openalex.org/W178216066","https://openalex.org/W1143091280","https://openalex.org/W1267585461","https://openalex.org/W1490646520","https://openalex.org/W1507651643","https://openalex.org/W1507976770","https://openalex.org/W1515844392","https://openalex.org/W1515948420","https://openalex.org/W1518668585","https://openalex.org/W1520087982","https://openalex.org/W1522532887","https://openalex.org/W1525285670","https://openalex.org/W1548688449","https://openalex.org/W1559758063","https://openalex.org/W1560901632","https://openalex.org/W1575383081","https://openalex.org/W1585385265","https://openalex.org/W1600517994","https://openalex.org/W1607014413","https://openalex.org/W1666139110","https://openalex.org/W1700316245","https://openalex.org/W1793473106","https://openalex.org/W1826357511","https://openalex.org/W1846625983","https://openalex.org/W1855484651","https://openalex.org/W1915414973","https://openalex.org/W1925558468","https://openalex.org/W1950769413","https://openalex.org/W1963708892","https://openalex.org/W1963820178","https://openalex.org/W1965357480","https://openalex.org/W1965622947","https://openalex.org/W1965987738","https://openalex.org/W1966339676","https://openalex.org/W1966706887","https://openalex.org/W1967667786","https://openalex.org/W1968410036","https://openalex.org/W1968684991","https://openalex.org/W1968881729","https://openalex.org/W1969292330","https://openalex.org/W1969848743","https://openalex.org/W1970205234","https://openalex.org/W1971619693","https://openalex.org/W1972762474","https://openalex.org/W1973749169","https://openalex.org/W1973779048","https://openalex.org/W1974130263","https://openalex.org/W1974163880","https://openalex.org/W1974482866","https://openalex.org/W1974519753","https://openalex.org/W1974669825","https://openalex.org/W1975755652","https://openalex.org/W1976561247","https://openalex.org/W1977747566","https://openalex.org/W1978240770","https://openalex.org/W1978763812","https://openalex.org/W1978930640","https://openalex.org/W1979346765","https://openalex.org/W1979782841","https://openalex.org/W1980415233","https://openalex.org/W1980464149","https://openalex.org/W1982085282","https://openalex.org/W1982254939","https://openalex.org/W1982459085","https://openalex.org/W1983195734","https://openalex.org/W1985074137","https://openalex.org/W1986992972","https://openalex.org/W1987070247","https://openalex.org/W1988176421","https://openalex.org/W1988723707","https://openalex.org/W1989569988","https://openalex.org/W1989710643","https://openalex.org/W1990048596","https://openalex.org/W1990456182","https://openalex.org/W1990580642","https://openalex.org/W1990832903","https://openalex.org/W1991353963","https://openalex.org/W1991395678","https://openalex.org/W1992257057","https://openalex.org/W1993431258","https://openalex.org/W1993735775","https://openalex.org/W1994041994","https://openalex.org/W1995069275","https://openalex.org/W1997003352","https://openalex.org/W1997369934","https://openalex.org/W1997593996","https://openalex.org/W1998032842","https://openalex.org/W1998771362","https://openalex.org/W1998842709","https://openalex.org/W2002064064","https://openalex.org/W2003702834","https://openalex.org/W2004866068","https://openalex.org/W2006084382","https://openalex.org/W2006705342","https://openalex.org/W2007818370","https://openalex.org/W2008970147","https://openalex.org/W2009810346","https://openalex.org/W2009936543","https://openalex.org/W2010238890","https://openalex.org/W2010763118","https://openalex.org/W2010786616","https://openalex.org/W2011211995","https://openalex.org/W2011239505","https://openalex.org/W2011282245","https://openalex.org/W2012549345","https://openalex.org/W2013346825","https://openalex.org/W2014032224","https://openalex.org/W2014813457","https://openalex.org/W2015402597","https://openalex.org/W2016310489","https://openalex.org/W2017534322","https://openalex.org/W2017919672","https://openalex.org/W2019677361","https://openalex.org/W2022630818","https://openalex.org/W2023819606","https://openalex.org/W2024214265","https://openalex.org/W2026967508","https://openalex.org/W2027004609","https://openalex.org/W2028786309","https://openalex.org/W2030525922","https://openalex.org/W2031581545","https://openalex.org/W2032661450","https://openalex.org/W2033355416","https://openalex.org/W2034677974","https://openalex.org/W2035016947","https://openalex.org/W2035654942","https://openalex.org/W2035730683","https://openalex.org/W2035912476","https://openalex.org/W2038193227","https://openalex.org/W2038227076","https://openalex.org/W2039212784","https://openalex.org/W2040221330","https://openalex.org/W2043513066","https://openalex.org/W2043698583","https://openalex.org/W2043933283","https://openalex.org/W2043967275","https://openalex.org/W2044073966","https://openalex.org/W2045668447","https://openalex.org/W2046422846","https://openalex.org/W2048418670","https://openalex.org/W2049713190","https://openalex.org/W2050203648","https://openalex.org/W2050427373","https://openalex.org/W2051245442","https://openalex.org/W2051753112","https://openalex.org/W2053469501","https://openalex.org/W2056137479","https://openalex.org/W2057782282","https://openalex.org/W2058382564","https://openalex.org/W2058606755","https://openalex.org/W2059825898","https://openalex.org/W2060836453","https://openalex.org/W2061112849","https://openalex.org/W2064539804","https://openalex.org/W2064977208","https://openalex.org/W2065705538","https://openalex.org/W2067979493","https://openalex.org/W2068342714","https://openalex.org/W2068385155","https://openalex.org/W2068547048","https://openalex.org/W2069081037","https://openalex.org/W2069142317","https://openalex.org/W2070910260","https://openalex.org/W2071199281","https://openalex.org/W2073361547","https://openalex.org/W2074894911","https://openalex.org/W2075167858","https://openalex.org/W2075707505","https://openalex.org/W2076514871","https://openalex.org/W2076694007","https://openalex.org/W2077230920","https://openalex.org/W2077266113","https://openalex.org/W2077672952","https://openalex.org/W2078190084","https://openalex.org/W2080647249","https://openalex.org/W2080927554","https://openalex.org/W2081289502","https://openalex.org/W2081620517","https://openalex.org/W2082853003","https://openalex.org/W2083229742","https://openalex.org/W2083677611","https://openalex.org/W2084513141","https://openalex.org/W2085232796","https://openalex.org/W2085567056","https://openalex.org/W2087136121","https://openalex.org/W2087279229","https://openalex.org/W2087591542","https://openalex.org/W2089289875","https://openalex.org/W2089415411","https://openalex.org/W2090494535","https://openalex.org/W2091144202","https://openalex.org/W2091263181","https://openalex.org/W2092514706","https://openalex.org/W2092696761","https://openalex.org/W2092833818","https://openalex.org/W2092946093","https://openalex.org/W2093226717","https://openalex.org/W2094503313","https://openalex.org/W2094853437","https://openalex.org/W2094941511","https://openalex.org/W2095358591","https://openalex.org/W2095433190","https://openalex.org/W2095539444","https://openalex.org/W2097225513","https://openalex.org/W2097318849","https://openalex.org/W2098595480","https://openalex.org/W2098864721","https://openalex.org/W2098947405","https://openalex.org/W2099479563","https://openalex.org/W2102312968","https://openalex.org/W2102891343","https://openalex.org/W2104342258","https://openalex.org/W2104456855","https://openalex.org/W2105663186","https://openalex.org/W2106302419","https://openalex.org/W2108483330","https://openalex.org/W2109121566","https://openalex.org/W2109263914","https://openalex.org/W2109958551","https://openalex.org/W2110671968","https://openalex.org/W2111568092","https://openalex.org/W2112668580","https://openalex.org/W2112879046","https://openalex.org/W2113222286","https://openalex.org/W2114339108","https://openalex.org/W2114349736","https://openalex.org/W2114825009","https://openalex.org/W2115664843","https://openalex.org/W2117833492","https://openalex.org/W2119041481","https://openalex.org/W2119820756","https://openalex.org/W2121480509","https://openalex.org/W2121709524","https://openalex.org/W2125747634","https://openalex.org/W2126015681","https://openalex.org/W2126496496","https://openalex.org/W2127295385","https://openalex.org/W2127481048","https://openalex.org/W2128637745","https://openalex.org/W2128968814","https://openalex.org/W2129683254","https://openalex.org/W2129975021","https://openalex.org/W2132084433","https://openalex.org/W2132444008","https://openalex.org/W2132463840","https://openalex.org/W2134061160","https://openalex.org/W2134130942","https://openalex.org/W2134138119","https://openalex.org/W2134183665","https://openalex.org/W2134580783","https://openalex.org/W2134757689","https://openalex.org/W2134871108","https://openalex.org/W2135704900","https://openalex.org/W2135899190","https://openalex.org/W2136166622","https://openalex.org/W2136272810","https://openalex.org/W2136748154","https://openalex.org/W2137882707","https://openalex.org/W2138226825","https://openalex.org/W2138319716","https://openalex.org/W2138623102","https://openalex.org/W2139424276","https://openalex.org/W2139436990","https://openalex.org/W2139937269","https://openalex.org/W2140533162","https://openalex.org/W2140630012","https://openalex.org/W2141514906","https://openalex.org/W2141556425","https://openalex.org/W2141978871","https://openalex.org/W2142504521","https://openalex.org/W2145134017","https://openalex.org/W2146027431","https://openalex.org/W2147284001","https://openalex.org/W2148652623","https://openalex.org/W2148792455","https://openalex.org/W2149891361","https://openalex.org/W2150569559","https://openalex.org/W2152651960","https://openalex.org/W2152665657","https://openalex.org/W2154319343","https://openalex.org/W2154591011","https://openalex.org/W2154929572","https://openalex.org/W2155465717","https://openalex.org/W2156209411","https://openalex.org/W2156687329","https://openalex.org/W2157307853","https://openalex.org/W2157316206","https://openalex.org/W2159023760","https://openalex.org/W2159536456","https://openalex.org/W2161024632","https://openalex.org/W2162817068","https://openalex.org/W2163497081","https://openalex.org/W2165583102","https://openalex.org/W2166251170","https://openalex.org/W2166583179","https://openalex.org/W2166632668","https://openalex.org/W2166714586","https://openalex.org/W2169015842","https://openalex.org/W2169520827","https://openalex.org/W2169898965","https://openalex.org/W2170720109","https://openalex.org/W2170933363","https://openalex.org/W2171217645","https://openalex.org/W2171893974","https://openalex.org/W2172189555","https://openalex.org/W2188300002","https://openalex.org/W2216710583","https://openalex.org/W2225270177","https://openalex.org/W2315982688","https://openalex.org/W2419382786","https://openalex.org/W2768498608","https://openalex.org/W7095786534"],"related_works":["https://openalex.org/W2069408589","https://openalex.org/W7095829389","https://openalex.org/W7099065928","https://openalex.org/W2061680286","https://openalex.org/W2111152746","https://openalex.org/W2800485840","https://openalex.org/W2899624998","https://openalex.org/W4407904414","https://openalex.org/W4220824424","https://openalex.org/W2106361856"],"abstract_inverted_index":{"Host":[0],"factors":[1,81],"are":[2,16],"crucial":[3,264],"in":[4,122,172,194,221,243,265],"determining":[5],"the":[6,54,78,109,158,190,214,239,285,312,316,332],"outcome":[7],"of":[8,49,56,112,157,179,192,213,273,288,331],"viral":[9,34,57,196,201,240],"infection.":[10,117],"As":[11],"obligate":[12],"intracellular":[13],"pathogens,":[14],"viruses":[15,229,306],"highly":[17,169],"dependent":[18,246],"on":[19,247],"numerous":[20],"cellular":[21,80,148,231,274],"proteins":[22],"and":[23,25,44,59,102,124,153,163,175,209,315,340],"processes,":[24],"also":[26,322],"must":[27],"evade":[28],"multiple":[29],"antiviral":[30],"defense":[31],"mechanisms.":[32],"Since":[33],"pathogens":[35,72],"represent":[36],"a":[37,46,135,168,244,329,343],"significant":[38],"threat":[39],"both":[40,121],"to":[41,98,145,188,233,270],"human":[42,71,199],"health":[43],"agriculture,":[45],"better":[47],"understanding":[48],"these":[50],"interactions":[51],"could":[52],"facilitate":[53],"treatment":[55],"infections":[58],"provide":[60,342],"novel":[61],"targets":[62],"for":[63,83,90,133,140,345],"therapeutics.":[64,348],"In":[65],"particular,":[66],"Poxviruses":[67],"include":[68],"medically":[69],"important":[70],"yet":[73],"little":[74],"is":[75,131,327],"known":[76,159],"about":[77],"specific":[79],"essential":[82,89],"their":[84],"replication.":[85],"To":[86],"identify":[87],"genes":[88,107],"vaccinia":[91,116],"infection,":[92,293],"I":[93,104,127,204,253],"used":[94],"high-throughput":[95],"RNA":[96,228,305,338],"interference":[97],"screen":[99],"Drosophila":[100],"kinases":[101],"phosphatases.":[103],"identified":[105],"seven":[106],"including":[108,150,198,311],"three":[110],"subunits":[111],"AMPK":[113,118,130,143,160,166,193,207,256,296,326],"as":[114,182],"promoting":[115],"facilitated":[119],"infection":[120,174,212],"insect":[123],"mammalian":[125],"cells.":[126],"found":[128,205,254],"that":[129,206,237,255,295,307],"required":[132],"macropinocytosis,":[134],"major":[136],"endocytic":[137],"entry":[138],"pathway":[139],"vaccinia.":[141],"Furthermore,":[142],"contributes":[144],"other":[146,195,227],"actin-dependent":[147],"processes":[149],"lamellipodia":[151],"formation":[152],"wound":[154],"healing,":[155],"independent":[156,178],"activators":[161],"LKB1":[162],"CaMKK.":[164],"Therefore,":[165],"plays":[167],"conserved":[170],"role":[171,181,191],"poxvirus":[173],"actin":[176],"dynamics":[177],"its":[180],"an":[183,222],"energy":[184],"regulator.\\nThis":[185],"led":[186],"me":[187],"investigate":[189],"infections,":[197],"arthropod-borne":[200],"pathogens.":[202],"Surprisingly":[203],"expression":[208],"activation":[210,257],"restricts":[211,297],"Bunyavirus":[215],"Rift":[216],"Valley":[217],"Fever":[218],"Virus":[219,320],"(RVFV)":[220],"LKB1-dependent":[223],"manner.":[224],"RVFV":[225,298],"like":[226],"manipulates":[230],"membranes":[232],"form":[234],"vesicle-like":[235],"structures":[236],"support":[238],"replication":[241],"complex":[242],"process":[245],"de":[248],"novo":[249],"fatty":[250,266,277,289,301],"acid":[251,267,278,290,302],"synthesis.":[252,303],"potently":[258],"inhibits":[259],"acetyl":[260],"Co":[261],"A":[262],"carboxylase,":[263],"synthesis,":[268],"leading":[269],"decreased":[271],"levels":[272],"lipids.":[275],"Bypassing":[276],"synthesis":[279,291],"by":[280,299,324],"treating":[281],"cells":[282],"with":[283],"palmitate,":[284],"first":[286],"product":[287],"rescued":[292],"demonstrating":[294],"inhibiting":[300],"Additional":[304],"require":[308],"membrane":[309],"proliferations":[310],"Togavirus":[313],"Sindbis":[314],"Alphavirus":[317],"Vesicular":[318],"Stomatitis":[319],"were":[321],"restricted":[323],"AMPK.":[325],"likely":[328],"component":[330],"intrinsic":[333],"innate":[334],"immune":[335],"response":[336],"against":[337],"viruses,":[339],"may":[341],"target":[344],"broadly":[346],"anti-viral":[347]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}