{"id":"https://openalex.org/W1576220084","doi":null,"title":"Aspectos biom\u00e9dicos de la familia de las lipocalinas","display_name":"Aspectos biom\u00e9dicos de la familia de las lipocalinas","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W1576220084","mag":"1576220084"},"language":"es","primary_location":{"id":"pmh:oai:doaj.org/article:dc36f539d9bd488b8c37eb44428ae330","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dc36f539d9bd488b8c37eb44428ae330","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Universitas Medica, Vol 48, Iss 2, Pp 118-128 (2007)","raw_type":"article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["doaj"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doaj.org/article/dc36f539d9bd488b8c37eb44428ae330","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027720893","display_name":"Gr\u00e9gory Alfonso Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gr\u00e9gory Alfonso Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074537238","display_name":"Dianney Clavijo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dianney Clavijo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041054837","display_name":"\u00d3mar Ram\u00f3n Mej\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u00d3mar Ram\u00f3n Mej\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003090689","display_name":"Anan\u00edas Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anan\u00edas Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062352096","display_name":"Mario Vittorino","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mario Vittorino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065571122","display_name":"Ciro Alfonso Casadiego","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ciro Alfonso Casadiego","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Sergio Hern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sergio Hern\u00e1ndez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Claudia Cobos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claudia Cobos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Jorge Tovar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jorge Tovar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028175559","display_name":"Carlos A. Rey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carlos Andr\u00e9s Rey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5012881859","display_name":"Camilo Mendoza Zamudio","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Camilo Zamudio","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11908","display_name":"Protein Interaction Studies and Fluorescence Analysis","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12030","display_name":"S100 Proteins and Annexins","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipocalin","display_name":"lipocalin","score":0.9589999914169312},{"id":"https://openalex.org/keywords/lipocalin-family","display_name":"lipocalin family","score":0.7300000190734863},{"id":"https://openalex.org/keywords/thyroid-hormones","display_name":"thyroid hormones","score":0.6850000023841858},{"id":"https://openalex.org/keywords/fatty-acids","display_name":"fatty acids","score":0.8690000176429749},{"id":"https://openalex.org/keywords/bile-acids","display_name":"bile acids","score":0.996999979019165},{"id":"https://openalex.org/keywords/iron-transport","display_name":"iron transport","score":0.8629999756813049},{"id":"https://openalex.org/keywords/neurophysiology","display_name":"neurophysiology","score":0.8849999904632568},{"id":"https://openalex.org/keywords/reproductive-physiology","display_name":"reproductive physiology","score":0.6869999766349792},{"id":"https://openalex.org/keywords/fertility","display_name":"fertility","score":0.6970000267028809},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.9100000262260437},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/disease-biomarkers","display_name":"disease biomarkers","score":0.5049999952316284}],"concepts":[{"id":"https://openalex.org/C15708023","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Humanities","level":1,"score":0.5865429639816284},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.37127530574798584},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.15962612628936768}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:doaj.org/article:dc36f539d9bd488b8c37eb44428ae330","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dc36f539d9bd488b8c37eb44428ae330","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Universitas Medica, Vol 48, Iss 2, Pp 118-128 (2007)","raw_type":"article"},{"id":"pmh:oai:redalyc.org:231018666005","doi":null,"is_oa":false,"landing_page_url":"https://www.redalyc.org/articulo.oa?id=231018666005","pdf_url":null,"source":{"id":"https://openalex.org/S4377196100","display_name":"Redalyc (Universidad Aut\u00f3noma del Estado de M\u00e9xico)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I179647637","host_organization_name":"Universidad Aut\u00f3noma del Estado de M\u00e9xico","host_organization_lineage":["https://openalex.org/I179647637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Universitas Medica (Colombia) Num.2 Vol.48","raw_type":"art\u00edculo cient\u00edfico"}],"best_oa_location":{"id":"pmh:oai:doaj.org/article:dc36f539d9bd488b8c37eb44428ae330","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dc36f539d9bd488b8c37eb44428ae330","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Universitas Medica, Vol 48, Iss 2, Pp 118-128 (2007)","raw_type":"article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7246000170707703}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1511203783","https://openalex.org/W1963515401","https://openalex.org/W1964911435","https://openalex.org/W1966507802","https://openalex.org/W1967731732","https://openalex.org/W1968045991","https://openalex.org/W1978111168","https://openalex.org/W1984844023","https://openalex.org/W1989642228","https://openalex.org/W1994708463","https://openalex.org/W1994834810","https://openalex.org/W1999183933","https://openalex.org/W2000489271","https://openalex.org/W2006698158","https://openalex.org/W2008083846","https://openalex.org/W2019758463","https://openalex.org/W2036815314","https://openalex.org/W2038438679","https://openalex.org/W2040141270","https://openalex.org/W2042871707","https://openalex.org/W2070977771","https://openalex.org/W2082241899","https://openalex.org/W2115940379","https://openalex.org/W2141412547","https://openalex.org/W2410358684"],"related_works":["https://openalex.org/W2256007459","https://openalex.org/W1513138351","https://openalex.org/W4394768552","https://openalex.org/W4400877542","https://openalex.org/W2040141270","https://openalex.org/W1966507802","https://openalex.org/W2015717581","https://openalex.org/W4240266819","https://openalex.org/W2401085060","https://openalex.org/W1994237451"],"abstract_inverted_index":{"La":[0],"familia":[1],"de":[2,8,22,40,85,110,123,126,135],"las":[3,43,47,50,124],"prote\u00ednas":[4],"lipocalinas":[5,72,129],"est\u00e1":[6],"compuesta":[7],"varios":[9],"miembros":[10],"que":[11,127],"comparten":[12],"una":[13,37],"estructura":[14],"com\u00fan,":[15],"definida":[16],"en":[17,27,75,79,82,91,97,105,115,132,137],"general":[18],"por":[19,31],"la":[20,76,80,83,86,89,92,98,102,106],"uni\u00f3n":[21],"ligandos":[23],"lipof\u00edlicos.":[24],"Se":[25],"expresan":[26],"forma":[28],"diferencial":[29],"espec\u00edfica":[30],"c\u00e9lulas":[32],"y":[33,35,67,88,94,101,104,117,145],"tejidos,":[34],"tienen":[36,130],"funci\u00f3n":[38,107],"extracelular":[39],"transporte":[41],"para":[42],"hormonas":[44,48],"lip\u00eddicas,":[45],"incluidas":[46],"tiroideas,":[49],"vitaminas":[51],"lip\u00eddicas":[52],"(complejo":[53],"vitam\u00ednico":[54],"A),":[55],"los":[56,59,64,68],"\u00e1cidos":[57,60],"grasos,":[58],"biliares,":[61],"el":[62],"hierro,":[63],"agentes":[65,69],"t\u00f3xicos":[66],"farmacol\u00f3gicos.":[70],"Las":[71],"est\u00e1n":[73],"implicadas":[74],"fisiolog\u00eda":[77,84],"hematoinmune,":[78],"neurofisiolog\u00eda,":[81],"reproducci\u00f3n":[87],"fertilidad,":[90],"proliferaci\u00f3n":[93],"divisi\u00f3n":[95],"celular,":[96],"supervivencia":[99],"celular":[100],"apoptosis,":[103],"enzim\u00e1tica":[108],"(bios\u00edntesis":[109],"prostanglandina":[111],"D2).":[112],"El":[113],"rol":[114],"patolog\u00eda":[116],"biocl\u00ednica":[118],"se":[119],"deriva":[120],"a":[121],"partir":[122],"observaciones":[125],"varias":[128],"alteraciones":[131],"sus":[133,146],"niveles":[134],"expresi\u00f3n":[136],"diferentes":[138],"trastornos.":[139],"Esta":[140],"revisi\u00f3n":[141],"resume":[142],"estos":[143],"hallazgos":[144],"implicaciones.":[147]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}