{"id":"https://openalex.org/W1576092697","doi":"https://doi.org/10.1097/hrp.0b013e318293749e","title":"Areas of the Brain Modulated by Single-Dose Methylphenidate Treatment in Youth with ADHD During Task-Based fMRI","display_name":"Areas of the Brain Modulated by Single-Dose Methylphenidate Treatment in Youth with ADHD During Task-Based fMRI","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1576092697","doi":"https://doi.org/10.1097/hrp.0b013e318293749e","mag":"1576092697","pmid":"https://pubmed.ncbi.nlm.nih.gov/23660970","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103657"},"language":"en","primary_location":{"id":"doi:10.1097/hrp.0b013e318293749e","doi":"https://doi.org/10.1097/hrp.0b013e318293749e","is_oa":false,"landing_page_url":"https://doi.org/10.1097/hrp.0b013e318293749e","pdf_url":null,"source":{"id":"https://openalex.org/S7919625","display_name":"Harvard Review of Psychiatry","issn_l":"1067-3229","issn":["1067-3229","1465-7309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Harvard Review of Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103657","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084781546","display_name":"Suzanne Czerniak","orcid":"https://orcid.org/0000-0002-7893-6680","observed_orcids":["https://orcid.org/0000-0002-7893-6680"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne M. Czerniak","raw_affiliation_strings":["University of Massachusetts Medical School, 303 Belmont St., Worcester, MA 01604, USA. Constance.Moore@umassmed.edu","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012","the University of Massachusetts Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Massachusetts Medical School, 303 Belmont St., Worcester, MA 01604, USA. Constance.Moore@umassmed.edu","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105003645","display_name":"Elif Muazzez \u015e\u0131ko\u011flu","orcid":"https://orcid.org/0000-0003-3838-7223","observed_orcids":["https://orcid.org/0000-0003-3838-7223"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elif M. Sikoglu","raw_affiliation_strings":["Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035404648","display_name":"Jean Anne King","orcid":"https://orcid.org/0000-0003-0061-0872","observed_orcids":["https://orcid.org/0000-0003-0061-0872"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean A. King","raw_affiliation_strings":["Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028579062","display_name":"David N. Kennedy","orcid":"https://orcid.org/0000-0002-9377-0797","observed_orcids":["https://orcid.org/0000-0002-9377-0797","https://orcid.org/0000-0001-7742-1792"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David N. Kennedy","raw_affiliation_strings":["Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071835676","display_name":"Eric O. Mick","orcid":"https://orcid.org/0000-0001-8505-8145","observed_orcids":["https://orcid.org/0000-0001-8505-8145"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric Mick","raw_affiliation_strings":["Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068971738","display_name":"Jean A. Frazier","orcid":"https://orcid.org/0000-0001-7055-3530","observed_orcids":["https://orcid.org/0000-0001-7055-3530"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean Frazier","raw_affiliation_strings":["Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091846635","display_name":"Constance M. Moore","orcid":"https://orcid.org/0000-0002-1099-5721","observed_orcids":["https://orcid.org/0000-0002-1099-5721"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Constance M. Moore","raw_affiliation_strings":["Constance M. Moore, PhD, Psychiatry/CCNI, 303 Belmont St., Worcester MA 01604. Email: [email\u00a0protected]","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","the University of Massachusetts Medical School","Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","revised manuscript received 23 August 2012"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Constance M. Moore, PhD, Psychiatry/CCNI, 303 Belmont St., Worcester MA 01604. Email: [email\u00a0protected]","institution_ids":[]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012; revised manuscript received 23 August 2012","institution_ids":[]},{"raw_affiliation_string":"the University of Massachusetts Medical School","institution_ids":["https://openalex.org/I166722992"]},{"raw_affiliation_string":"Original manuscript received 4 June 2012, accepted for publication subject to revision 5 August 2012","institution_ids":[]},{"raw_affiliation_string":"revised manuscript received 23 August 2012","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5091846635"],"corresponding_institution_ids":["https://openalex.org/I166722992"],"apc_list":null,"apc_paid":null,"fwci":3.3732,"has_fulltext":false,"cited_by_count":63,"citation_normalized_percentile":{"value":0.91946771,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"21","issue":"3","first_page":"151","last_page":"162"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10042","display_name":"Neural and Behavioral Psychology Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9890000224113464},{"id":"https://openalex.org/keywords/methylphenidate","display_name":"methylphenidate","score":0.9750000238418579},{"id":"https://openalex.org/keywords/children-with-adhd","display_name":"children with ADHD","score":0.8080000281333923},{"id":"https://openalex.org/keywords/stimulant-medication-effects","display_name":"stimulant medication effects","score":0.6019999980926514},{"id":"https://openalex.org/keywords/brain-activation","display_name":"brain activation","score":0.8050000071525574},{"id":"https://openalex.org/keywords/frontal-lobe","display_name":"frontal lobe","score":0.7300000190734863},{"id":"https://openalex.org/keywords/basal-ganglia","display_name":"basal ganglia","score":0.9480000138282776},{"id":"https://openalex.org/keywords/cerebellum","display_name":"cerebellum","score":1.0},{"id":"https://openalex.org/keywords/inhibitory-control","display_name":"inhibitory control","score":0.9190000295639038},{"id":"https://openalex.org/keywords/task-based-fmri","display_name":"task-based fMRI","score":0.8159999847412109},{"id":"https://openalex.org/keywords/symptom-improvement","display_name":"symptom improvement","score":0.6100000143051147}],"concepts":[{"id":"https://openalex.org/C2777112843","wikidata":"https://www.wikidata.org/wiki/Q422112","display_name":"Methylphenidate","level":3,"score":0.9256749749183655},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.6978645324707031},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.67518550157547},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.6533293128013611},{"id":"https://openalex.org/C2778187257","wikidata":"https://www.wikidata.org/wiki/Q464210","display_name":"Basal ganglia","level":3,"score":0.6022413969039917},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5356281399726868},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.46096253395080566},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4256754219532013},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.41569846868515015},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3680298924446106},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.3549495339393616},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.16747432947158813},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.13174954056739807}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001289","descriptor_name":"Attention Deficit Disorder with Hyperactivity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001289","descriptor_name":"Attention Deficit Disorder with Hyperactivity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001479","descriptor_name":"Basal Ganglia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001479","descriptor_name":"Basal Ganglia","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008774","descriptor_name":"Methylphenidate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D008774","descriptor_name":"Methylphenidate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D059907","descriptor_name":"Functional Neuroimaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1097/hrp.0b013e318293749e","doi":"https://doi.org/10.1097/hrp.0b013e318293749e","is_oa":false,"landing_page_url":"https://doi.org/10.1097/hrp.0b013e318293749e","pdf_url":null,"source":{"id":"https://openalex.org/S7919625","display_name":"Harvard Review of Psychiatry","issn_l":"1067-3229","issn":["1067-3229","1465-7309"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Harvard Review of Psychiatry","raw_type":"journal-article"},{"id":"pmid:23660970","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23660970","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Harvard review of psychiatry","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3072562","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103657","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4103657","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103657","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Harv Rev Psychiatry","raw_type":"Text"},{"id":"pmh:oai:escholarship.umassmed.edu:faculty_pubs-1267","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.umassmed.edu/faculty_pubs/268","pdf_url":null,"source":{"id":"https://openalex.org/S4306400883","display_name":"The Journal of the American Medical Association (JAMA) Network (American Medical Association)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173654999","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/I173654999"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"University of Massachusetts Medical School Faculty Publications","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3072562","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4103657","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[{"id":"https://openalex.org/G7544926963","display_name":"Intellectual and Developmental Disabilities Research Center","funder_award_id":"P30HD004147","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7802837422","display_name":"Exposing the Deep Content of the Publication: Knowledge Extraction for Neuroimaging in Child Psychiatry","funder_award_id":"R01MH083320","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7824450033","display_name":"Glutamine and Glutamate in Children and Adolescents with Bipolar Disorder","funder_award_id":"R01MH073998","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"}],"funders":[{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1694107652","https://openalex.org/W1832744912","https://openalex.org/W1966294386","https://openalex.org/W1971144159","https://openalex.org/W1974649221","https://openalex.org/W1995992264","https://openalex.org/W1999405675","https://openalex.org/W2001355988","https://openalex.org/W2016511885","https://openalex.org/W2034192100","https://openalex.org/W2038098373","https://openalex.org/W2040224729","https://openalex.org/W2050444644","https://openalex.org/W2057916658","https://openalex.org/W2059192453","https://openalex.org/W2066434718","https://openalex.org/W2067282805","https://openalex.org/W2072495786","https://openalex.org/W2075476435","https://openalex.org/W2081722843","https://openalex.org/W2094590423","https://openalex.org/W2095665480","https://openalex.org/W2103681669","https://openalex.org/W2110412456","https://openalex.org/W2113225772","https://openalex.org/W2113754559","https://openalex.org/W2115518880","https://openalex.org/W2118813346","https://openalex.org/W2119393646","https://openalex.org/W2122694895","https://openalex.org/W2123934982","https://openalex.org/W2124827486","https://openalex.org/W2132921554","https://openalex.org/W2134612212","https://openalex.org/W2135691106","https://openalex.org/W2143962520","https://openalex.org/W2145020179","https://openalex.org/W2148974261","https://openalex.org/W2164407653","https://openalex.org/W2166617025","https://openalex.org/W2166930870","https://openalex.org/W2171074660","https://openalex.org/W2405138604","https://openalex.org/W4252967894"],"related_works":["https://openalex.org/W7073917771","https://openalex.org/W7096977214","https://openalex.org/W2365864211","https://openalex.org/W2119822070","https://openalex.org/W2001355988","https://openalex.org/W2050444644","https://openalex.org/W4306647837","https://openalex.org/W2143962520","https://openalex.org/W2057916658","https://openalex.org/W768640314"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Attention-deficit/hyperactivity":[1],"disorder":[2,7],"(ADHD)":[3],"is":[4,14],"a":[5,15,62],"psychiatric":[6],"affecting":[8],"5%":[9],"of":[10,42,52,65,136,193,213,237],"children.":[11,249],"Methylphenidate":[12],"(MPH)":[13],"common":[16],"medication":[17],"for":[18],"ADHD.":[19],"Studies":[20],"examining":[21],"MPH's":[22,208],"effect":[23,209],"on":[24,141,210],"pediatric":[25,56,214],"ADHD":[26,57,113,146],"patients'":[27],"brain":[28,54,87,181,241],"function":[29],"using":[30,109],"functional":[31],"magnetic":[32],"resonance":[33],"imaging":[34],"(fMRI)":[35],"have":[36],"not":[37,187],"been":[38],"compiled.":[39],"The":[40,164],"goals":[41],"this":[43,233],"systematic":[44],"review":[45],"were":[46,138,158,170],"to":[47,90,93,190,243],"determine":[48],"(1)":[49],"which":[50,137],"areas":[51,69,242],"the":[53,102,110,148,191,198,211],"in":[55,86,96,220,246],"patients":[58,147,215],"are":[59],"modulated":[60,70],"by":[61,71,74,162,173],"single":[63],"dose":[64],"MPH,":[66],"(2)":[67],"whether":[68,84],"MPH":[72,91,117,174,218],"differ":[73],"task":[75],"type":[76],"performed":[77],"during":[78,175],"fMRI":[79,125,205],"data":[80],"acquisition,":[81],"and":[82,106,131,150,156,166,183,228],"(3)":[83],"changes":[85],"activation":[88,222,236],"due":[89,189],"relate":[92],"clinical":[94,184],"improvements":[95],"ADHD-related":[97],"symptoms.":[98],"METHODS:":[99],"We":[100],"searched":[101],"electronic":[103],"databases":[104],"PubMed":[105],"PsycINFO":[107],"(1967-2011)":[108],"following":[111],"terms:":[112],"AND":[114,120],"(methylphenidate":[115],"OR":[116,118,122,124,126,128],"ritalin)":[119],"(neuroimaging":[121],"MRI":[123],"BOLD":[127],"event":[129],"related),":[130],"identified":[132],"200":[133],"abstracts,":[134],"9":[135],"reviewed":[139],"based":[140],"predefined":[142],"criteria.":[143],"RESULTS:":[144],"In":[145,230],"middle":[149,165],"inferior":[151,167],"frontal":[152,168,224],"gyri,":[153],"basal":[154,226],"ganglia,":[155,227],"cerebellum":[157],"most":[159,231],"often":[160],"affected":[161,172],"MPH.":[163],"gyri":[169],"frequently":[171],"inhibitory":[176],"control":[177],"tasks.":[178],"Correlation":[179],"between":[180],"regions":[182],"improvement":[185,195],"was":[186],"possible":[188],"lack":[192],"symptom":[194],"measures":[196],"within":[197,223],"included":[199],"studies.":[200],"CONCLUSIONS:":[201],"Throughout":[202],"nine":[203],"task-based":[204],"studies":[206],"investigating":[207],"brains":[212],"with":[216],"ADHD,":[217],"resulted":[219],"increased":[221],"lobes,":[225],"cerebellum.":[229],"cases,":[232],"increase":[234],"\"normalized\"":[235],"at":[238],"least":[239],"some":[240],"that":[244],"seen":[245],"typically":[247],"developing":[248]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}