{"id":"https://openalex.org/W1574448647","doi":"https://doi.org/10.1002/ps.3616","title":"Molecular cloning and characterization of a ryanodine receptor gene in brown planthopper ( BPH ), Nilaparvata lugens (St\u00e5l)","display_name":"Molecular cloning and characterization of a ryanodine receptor gene in brown planthopper ( BPH ), Nilaparvata lugens (St\u00e5l)","publication_year":2013,"publication_date":"2013-07-26","ids":{"openalex":"https://openalex.org/W1574448647","doi":"https://doi.org/10.1002/ps.3616","mag":"1574448647","pmid":"https://pubmed.ncbi.nlm.nih.gov/23893901"},"language":"en","primary_location":{"id":"doi:10.1002/ps.3616","doi":"https://doi.org/10.1002/ps.3616","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ps.3616","pdf_url":null,"source":{"id":"https://openalex.org/S31777576","display_name":"Pest Management Science","issn_l":"1526-498X","issn":["1526-498X","1526-4998"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pest Management Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5159583633","display_name":"Jian Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Wang","raw_affiliation_strings":["College of Horticulture and Plant Protection, Yangzhou University Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection, Yangzhou University Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103355011","display_name":"Zhijuan Xie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhijuan Xie","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007956132","display_name":"Jingkun Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingkun Gao","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159588402","display_name":"Yaping Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaping Liu","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5159734225","display_name":"Wenlong Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenlong Wang","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129723071","display_name":"Li Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Huang","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5148175175","display_name":"Jianjun Wang","orcid":"https://orcid.org/0000-0001-9113-7894","observed_orcids":["https://orcid.org/0000-0001-9113-7894"]},"institutions":[{"id":"https://openalex.org/I78978612","display_name":"Yangzhou University","ror":"https://ror.org/03tqb8s11","country_code":"CN","type":"education","lineage":["https://openalex.org/I78978612"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianjun Wang","raw_affiliation_strings":["College of Horticulture and Plant Protection Yangzhou University Yangzhou China","Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Horticulture and Plant Protection Yangzhou University Yangzhou China","institution_ids":["https://openalex.org/I78978612"]},{"raw_affiliation_string":"Yangzhou University, College of Horticulture and Plant Protection, Yangzhou, China","institution_ids":["https://openalex.org/I78978612"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5148175175"],"corresponding_institution_ids":["https://openalex.org/I78978612"],"apc_list":{"value":5360,"currency":"USD","value_usd":5360},"apc_paid":null,"fwci":1.7909,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.83963157,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"70","issue":"5","first_page":"790","last_page":"797"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.9297000169754028,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.03739999979734421,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.004100000020116568,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ryanodine-receptor","display_name":"ryanodine receptor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nilaparvata-lugens","display_name":"Nilaparvata lugens","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.8159999847412109},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.9800000190734863},{"id":"https://openalex.org/keywords/splice-variants","display_name":"splice variants","score":0.7089999914169312},{"id":"https://openalex.org/keywords/developmental-stage-expression","display_name":"developmental stage expression","score":0.8399999737739563},{"id":"https://openalex.org/keywords/insecticide-targets","display_name":"insecticide targets","score":0.4970000088214874},{"id":"https://openalex.org/keywords/rice-pests","display_name":"rice pests","score":0.6110000014305115}],"concepts":[{"id":"https://openalex.org/C113217602","wikidata":"https://www.wikidata.org/wiki/Q416781","display_name":"Ryanodine receptor","level":3,"score":0.8471231460571289},{"id":"https://openalex.org/C2776036430","wikidata":"https://www.wikidata.org/wiki/Q3595463","display_name":"Brown planthopper","level":3,"score":0.7984189391136169},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6745673418045044},{"id":"https://openalex.org/C2779394805","wikidata":"https://www.wikidata.org/wiki/Q2558803","display_name":"Delphacidae","level":4,"score":0.5742737650871277},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.5371103882789612},{"id":"https://openalex.org/C47289529","wikidata":"https://www.wikidata.org/wiki/Q908550","display_name":"Open reading frame","level":4,"score":0.49671274423599243},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.49130192399024963},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4564637243747711},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.4322054386138916},{"id":"https://openalex.org/C2778776201","wikidata":"https://www.wikidata.org/wiki/Q3474283","display_name":"Exon skipping","level":5,"score":0.4119594097137451},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.3750687539577484},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.34339314699172974},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3423495292663574},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.33255359530448914},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.29658243060112},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.17925524711608887},{"id":"https://openalex.org/C22508944","wikidata":"https://www.wikidata.org/wiki/Q568174","display_name":"PEST analysis","level":2,"score":0.09189227223396301},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.07160785794258118},{"id":"https://openalex.org/C2776988988","wikidata":"https://www.wikidata.org/wiki/Q921647","display_name":"Homoptera","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006430","descriptor_name":"Hemiptera","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006430","descriptor_name":"Hemiptera","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006430","descriptor_name":"Hemiptera","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009758","descriptor_name":"Nymph","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009758","descriptor_name":"Nymph","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010063","descriptor_name":"Ovum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017398","descriptor_name":"Alternative Splicing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019476","descriptor_name":"Insect Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019837","descriptor_name":"Ryanodine Receptor Calcium Release Channel","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019837","descriptor_name":"Ryanodine Receptor Calcium Release Channel","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019837","descriptor_name":"Ryanodine Receptor Calcium Release Channel","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/ps.3616","doi":"https://doi.org/10.1002/ps.3616","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ps.3616","pdf_url":null,"source":{"id":"https://openalex.org/S31777576","display_name":"Pest Management Science","issn_l":"1526-498X","issn":["1526-498X","1526-4998"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pest Management Science","raw_type":"journal-article"},{"id":"pmid:23893901","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23893901","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pest management science","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.4359000027179718,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316011","display_name":"Basis Foundation","ror":"https://ror.org/05v6e7y40"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1479663228","https://openalex.org/W1525891657","https://openalex.org/W1604648602","https://openalex.org/W1963674303","https://openalex.org/W1982430817","https://openalex.org/W1984865370","https://openalex.org/W1989256274","https://openalex.org/W1991593687","https://openalex.org/W1991693578","https://openalex.org/W1993548952","https://openalex.org/W2004326327","https://openalex.org/W2011295628","https://openalex.org/W2011809437","https://openalex.org/W2013023765","https://openalex.org/W2018132020","https://openalex.org/W2020089365","https://openalex.org/W2020708981","https://openalex.org/W2025685317","https://openalex.org/W2028432816","https://openalex.org/W2031859242","https://openalex.org/W2033696364","https://openalex.org/W2034683920","https://openalex.org/W2040179837","https://openalex.org/W2041379145","https://openalex.org/W2042026265","https://openalex.org/W2045661547","https://openalex.org/W2047442532","https://openalex.org/W2047534013","https://openalex.org/W2048209497","https://openalex.org/W2049400321","https://openalex.org/W2058268583","https://openalex.org/W2062985112","https://openalex.org/W2064831048","https://openalex.org/W2066027471","https://openalex.org/W2070524783","https://openalex.org/W2070618528","https://openalex.org/W2072471403","https://openalex.org/W2074065761","https://openalex.org/W2075989491","https://openalex.org/W2079637246","https://openalex.org/W2089838586","https://openalex.org/W2095017632","https://openalex.org/W2096827547","https://openalex.org/W2102792655","https://openalex.org/W2105877571","https://openalex.org/W2106882534","https://openalex.org/W2114805428","https://openalex.org/W2115900546","https://openalex.org/W2137283585","https://openalex.org/W2142660310","https://openalex.org/W2165677897","https://openalex.org/W2179619678","https://openalex.org/W2408350377"],"related_works":["https://openalex.org/W2488597375","https://openalex.org/W7096813577","https://openalex.org/W2034683920","https://openalex.org/W2410316518","https://openalex.org/W2004669808","https://openalex.org/W2054479520","https://openalex.org/W7098119887","https://openalex.org/W2078737420","https://openalex.org/W2292172411","https://openalex.org/W1512337725"],"abstract_inverted_index":{"BACKGROUND:":[0],"Ryanodine":[1],"receptors":[2],"(RyRs)":[3],"are":[4,121],"a":[5,46,61,82],"distinct":[6],"class":[7],"of":[8,17,33,77,84,117,152,176,219,222,232,245],"intracellular":[9],"calcium":[10],"(Ca(2+))":[11],"release":[12],"channel.":[13],"The":[14,68,234],"recent":[15],"discovery":[16],"diamide":[18],"insecticides":[19],"has":[20],"prompted":[21],"studies":[22],"on":[23],"insect":[24,34,97,189],"RyRs.":[25],"However,":[26],"information":[27],"about":[28],"the":[29,53,118,124,128,179,196,217,229,237],"structure":[30],"and":[31,44,112,137,141,143,184,242],"function":[32],"RyRs":[35],"is":[36,185],"still":[37],"limited.":[38],"In":[39],"this":[40],"study,":[41],"we":[42],"isolated":[43],"characterized":[45],"full-length":[47],"RyR":[48,119,129,138,142],"cDNA":[49],"(named":[50],"NlRyR)":[51],"from":[52],"brown":[54],"planthopper,":[55],"Nilaparvata":[56],"lugens":[57,163],"(St\u00e5l)":[58],"(Homoptera:":[59],"Delphacidae),":[60],"serious":[62],"rice":[63],"pest":[64],"throughout":[65],"Asia.":[66],"RESULTS:":[67],"composite":[69],"NlRyR":[70,125,153,210],"gene":[71],"contains":[72],"an":[73,213],"open":[74],"reading":[75],"frame":[76],"15":[78],"423":[79],"bp":[80],"encoding":[81],"protein":[83],"5140":[85],"amino":[86],"acid":[87],"residues,":[88],"which":[89,177],"shares":[90],"high":[91],"sequence":[92],"identity":[93,110],"(78-81%)":[94],"with":[95,107],"other":[96],"homologues,":[98],"except":[99],"for":[100,239],"two":[101],"regions":[102],"(IDR1:":[103],"4379-4732;":[104],"IDR2:":[105],"1307-1529)":[106],"markedly":[108],"low":[109],"(44-48":[111],"38-41%,":[113],"respectively).":[114],"All":[115],"hallmarks":[116],"proteins":[120],"conserved":[122,186],"in":[123,157,173,187,205,216],"protein,":[126],"including":[127],"domain":[130],"as":[131,133],"well":[132],"mannosyltransferase,":[134],"IP3":[135,144],"R":[136,145],"(pfam02815)":[139],"(MIR)":[140],"homology":[146],"(pfam01365)":[147],"(RIH)":[148],"domains.":[149],"Expression":[150],"analysis":[151],"revealed":[154],"significant":[155],"differences":[156],"mRNA":[158],"expression":[159],"levels":[160],"among":[161],"N.":[162,223],"developmental":[164,207,220],"stages.":[165,208],"Furthermore,":[166],"three":[167],"alternative":[168],"splicing":[169,226],"sites":[170],"were":[171],"identified":[172],"NlRyR,":[174],"one":[175],"forms":[178],"mutually":[180],"exclusive":[181],"exons":[182],"A/B":[183],"various":[188],"species.":[190],"Diagnostic":[191],"PCR":[192],"assays":[193],"showed":[194],"that":[195],"splice":[197],"variant":[198],"containing":[199],"exon":[200],"A":[201],"was":[202],"predominantly":[203],"detected":[204],"all":[206],"CONCLUSION:":[209],"may":[211,227],"play":[212],"important":[214],"role":[215],"control":[218],"processes":[221],"lugens.":[224],"Alternative":[225],"generate":[228],"functional":[230,243],"diversity":[231],"NlRyR.":[233,246],"results":[235],"provided":[236],"basis":[238],"further":[240],"structural":[241],"characterization":[244]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}