{"id":"https://openalex.org/W1573814705","doi":null,"title":"FUNCTIONAL PLASTICITY OF HIPPOCAMPAL GLUTAMATERGIC SYNAPSES IN DEVELOPMENT AND DISEASE","display_name":"FUNCTIONAL PLASTICITY OF HIPPOCAMPAL GLUTAMATERGIC SYNAPSES IN DEVELOPMENT AND DISEASE","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W1573814705","mag":"1573814705"},"language":"en","primary_location":{"id":"pmh:oai:repository.upenn.edu:edissertations-1444","doi":null,"is_oa":true,"landing_page_url":"https://repository.upenn.edu/edissertations/332","pdf_url":"https://repository.upenn.edu/edissertations/332","source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Publicly Accessible Penn Dissertations","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://repository.upenn.edu/edissertations/332","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101532565","display_name":"Xiaoyu Peng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Xiaoyu Peng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5101532565"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.8349999785423279},{"id":"https://openalex.org/keywords/glutamatergic-synapses","display_name":"glutamatergic synapses","score":0.9959999918937683},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.9190000295639038},{"id":"https://openalex.org/keywords/presynaptic-terminals","display_name":"presynaptic terminals","score":0.9380000233650208},{"id":"https://openalex.org/keywords/synaptic-development","display_name":"synaptic development","score":0.4740000069141388},{"id":"https://openalex.org/keywords/neurological-disorders","display_name":"neurological disorders","score":0.7770000100135803},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"cognitive impairment","score":0.47099998593330383}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.8255221843719482},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.7318063974380493},{"id":"https://openalex.org/C154559735","wikidata":"https://www.wikidata.org/wiki/Q7514768","display_name":"Silent synapse","level":5,"score":0.6173229217529297},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.5781358480453491},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.5756562948226929},{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.5605761408805847},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5133087038993835},{"id":"https://openalex.org/C25274449","wikidata":"https://www.wikidata.org/wiki/Q1805481","display_name":"Long-term potentiation","level":3,"score":0.4866364896297455},{"id":"https://openalex.org/C2779530196","wikidata":"https://www.wikidata.org/wiki/Q178999","display_name":"Axon","level":2,"score":0.4833900034427643},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.458880752325058},{"id":"https://openalex.org/C118403218","wikidata":"https://www.wikidata.org/wiki/Q43283","display_name":"Biological neural network","level":2,"score":0.45002278685569763},{"id":"https://openalex.org/C194973443","wikidata":"https://www.wikidata.org/wiki/Q1420291","display_name":"Metaplasticity","level":4,"score":0.4387741684913635},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.4275302290916443},{"id":"https://openalex.org/C545706735","wikidata":"https://www.wikidata.org/wiki/Q9404","display_name":"Nervous system","level":2,"score":0.42296287417411804},{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.3198518753051758},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.30304837226867676},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.2228248119354248},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"pmh:oai:repository.upenn.edu:edissertations-1444","doi":null,"is_oa":true,"landing_page_url":"https://repository.upenn.edu/edissertations/332","pdf_url":"https://repository.upenn.edu/edissertations/332","source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Publicly Accessible Penn Dissertations","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.222.6273","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.222.6273","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.649.4560","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.649.4560","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:repository.upenn.edu:20.500.14332/30331","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/handle/20.500.14332/30331","pdf_url":null,"source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"published","raw_type":"Dissertation/Thesis"},{"id":"pmh:oai:repository.upenn.edu:dissertations-10144","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/dissertations/AAI3463080","pdf_url":null,"source":{"id":"https://openalex.org/S4377196331","display_name":"Scholarly Commons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dissertations available from ProQuest","raw_type":"text"},{"id":"mag:1573814705","doi":null,"is_oa":false,"landing_page_url":"https://repository.upenn.edu/cgi/viewcontent.cgi?article=10144&context=dissertations","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.upenn.edu:edissertations-1444","doi":null,"is_oa":true,"landing_page_url":"https://repository.upenn.edu/edissertations/332","pdf_url":"https://repository.upenn.edu/edissertations/332","source":{"id":"https://openalex.org/S4306402083","display_name":"ScholarlyCommons (University of Pennsylvania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79576946","host_organization_name":"University of Pennsylvania","host_organization_lineage":["https://openalex.org/I79576946"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Publicly Accessible Penn Dissertations","raw_type":"text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320308324","display_name":"McKnight Foundation","ror":"https://ror.org/003ghvj67"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1573814705.pdf","grobid_xml":"https://content.openalex.org/works/W1573814705.grobid-xml"},"referenced_works_count":228,"referenced_works":["https://openalex.org/W216844364","https://openalex.org/W1011816361","https://openalex.org/W1483422351","https://openalex.org/W1494623690","https://openalex.org/W1498241934","https://openalex.org/W1503881830","https://openalex.org/W1514853588","https://openalex.org/W1517253433","https://openalex.org/W1521104469","https://openalex.org/W1534720449","https://openalex.org/W1545468864","https://openalex.org/W1558650798","https://openalex.org/W1568903867","https://openalex.org/W1577190501","https://openalex.org/W1580101590","https://openalex.org/W1605213317","https://openalex.org/W1629617176","https://openalex.org/W1838712517","https://openalex.org/W1845163922","https://openalex.org/W1912510903","https://openalex.org/W1922786159","https://openalex.org/W1955716838","https://openalex.org/W1965782413","https://openalex.org/W1966020111","https://openalex.org/W1966481477","https://openalex.org/W1967302106","https://openalex.org/W1967804600","https://openalex.org/W1969600766","https://openalex.org/W1970053578","https://openalex.org/W1970328639","https://openalex.org/W1970729216","https://openalex.org/W1970897832","https://openalex.org/W1970992446","https://openalex.org/W1974255593","https://openalex.org/W1974897738","https://openalex.org/W1977384016","https://openalex.org/W1978842225","https://openalex.org/W1979535275","https://openalex.org/W1980573935","https://openalex.org/W1980750700","https://openalex.org/W1982099631","https://openalex.org/W1983404333","https://openalex.org/W1983627336","https://openalex.org/W1984743194","https://openalex.org/W1985241009","https://openalex.org/W1986086807","https://openalex.org/W1987281769","https://openalex.org/W1988938063","https://openalex.org/W1989670552","https://openalex.org/W1989938166","https://openalex.org/W1990646890","https://openalex.org/W1991444801","https://openalex.org/W1992156523","https://openalex.org/W1993394859","https://openalex.org/W1995254751","https://openalex.org/W1995855359","https://openalex.org/W1996669272","https://openalex.org/W1996807387","https://openalex.org/W1997591291","https://openalex.org/W2000097259","https://openalex.org/W2000300989","https://openalex.org/W2002426329","https://openalex.org/W2003179182","https://openalex.org/W2003712515","https://openalex.org/W2005686453","https://openalex.org/W2005704128","https://openalex.org/W2007487855","https://openalex.org/W2008643711","https://openalex.org/W2008986992","https://openalex.org/W2009894997","https://openalex.org/W2010394656","https://openalex.org/W2010778459","https://openalex.org/W2011748173","https://openalex.org/W2012635381","https://openalex.org/W2012641732","https://openalex.org/W2012678641","https://openalex.org/W2013319332","https://openalex.org/W2013880564","https://openalex.org/W2013918392","https://openalex.org/W2014907593","https://openalex.org/W2015556634","https://openalex.org/W2017255010","https://openalex.org/W2018755652","https://openalex.org/W2018775189","https://openalex.org/W2019016101","https://openalex.org/W2019606391","https://openalex.org/W2022963868","https://openalex.org/W2026899274","https://openalex.org/W2027265162","https://openalex.org/W2027436298","https://openalex.org/W2027547809","https://openalex.org/W2028789389","https://openalex.org/W2028884770","https://openalex.org/W2030377743","https://openalex.org/W2031779883","https://openalex.org/W2035870268","https://openalex.org/W2037068170","https://openalex.org/W2037812600","https://openalex.org/W2037921808","https://openalex.org/W2038632213","https://openalex.org/W2041328200","https://openalex.org/W2041525670","https://openalex.org/W2042984003","https://openalex.org/W2044031472","https://openalex.org/W2044049987","https://openalex.org/W2045107841","https://openalex.org/W2045878719","https://openalex.org/W2046542358","https://openalex.org/W2047397502","https://openalex.org/W2047560376","https://openalex.org/W2048249509","https://openalex.org/W2048570296","https://openalex.org/W2050692084","https://openalex.org/W2050819309","https://openalex.org/W2051378734","https://openalex.org/W2051434331","https://openalex.org/W2051524905","https://openalex.org/W2055186048","https://openalex.org/W2055374196","https://openalex.org/W2056366478","https://openalex.org/W2056389198","https://openalex.org/W2056468240","https://openalex.org/W2057502000","https://openalex.org/W2057759105","https://openalex.org/W2058544036","https://openalex.org/W2060012772","https://openalex.org/W2060304640","https://openalex.org/W2061056490","https://openalex.org/W2062474690","https://openalex.org/W2063705377","https://openalex.org/W2064226680","https://openalex.org/W2064579290","https://openalex.org/W2065169750","https://openalex.org/W2065588791","https://openalex.org/W2066933851","https://openalex.org/W2067814945","https://openalex.org/W2069536209","https://openalex.org/W2072389508","https://openalex.org/W2072597173","https://openalex.org/W2073461489","https://openalex.org/W2073928226","https://openalex.org/W2074557008","https://openalex.org/W2080611091","https://openalex.org/W2082386266","https://openalex.org/W2082411508","https://openalex.org/W2082443574","https://openalex.org/W2083203380","https://openalex.org/W2084200464","https://openalex.org/W2087351063","https://openalex.org/W2087363103","https://openalex.org/W2087444289","https://openalex.org/W2087648078","https://openalex.org/W2087728854","https://openalex.org/W2087875541","https://openalex.org/W2089211424","https://openalex.org/W2089883236","https://openalex.org/W2092059640","https://openalex.org/W2092326283","https://openalex.org/W2093248761","https://openalex.org/W2093842498","https://openalex.org/W2094212507","https://openalex.org/W2096156320","https://openalex.org/W2097738233","https://openalex.org/W2098703603","https://openalex.org/W2099408092","https://openalex.org/W2099762599","https://openalex.org/W2099848840","https://openalex.org/W2100701643","https://openalex.org/W2102092558","https://openalex.org/W2105600079","https://openalex.org/W2107022519","https://openalex.org/W2114398221","https://openalex.org/W2119257893","https://openalex.org/W2120938812","https://openalex.org/W2121402661","https://openalex.org/W2121799179","https://openalex.org/W2122037734","https://openalex.org/W2123159874","https://openalex.org/W2123376780","https://openalex.org/W2124517960","https://openalex.org/W2126656642","https://openalex.org/W2129361777","https://openalex.org/W2129866650","https://openalex.org/W2130784302","https://openalex.org/W2133138154","https://openalex.org/W2133423973","https://openalex.org/W2133598902","https://openalex.org/W2133623572","https://openalex.org/W2134236497","https://openalex.org/W2135719485","https://openalex.org/W2138368199","https://openalex.org/W2138554514","https://openalex.org/W2138903675","https://openalex.org/W2139487267","https://openalex.org/W2139741076","https://openalex.org/W2140156016","https://openalex.org/W2141111992","https://openalex.org/W2141550849","https://openalex.org/W2143285990","https://openalex.org/W2146199022","https://openalex.org/W2147259071","https://openalex.org/W2147528615","https://openalex.org/W2147542138","https://openalex.org/W2149184122","https://openalex.org/W2153173068","https://openalex.org/W2153730779","https://openalex.org/W2154100802","https://openalex.org/W2154803724","https://openalex.org/W2156177514","https://openalex.org/W2156631744","https://openalex.org/W2157402130","https://openalex.org/W2158561409","https://openalex.org/W2159289827","https://openalex.org/W2161681716","https://openalex.org/W2162019295","https://openalex.org/W2162593608","https://openalex.org/W2164674870","https://openalex.org/W2165696259","https://openalex.org/W2166759337","https://openalex.org/W2167768159","https://openalex.org/W2170946991","https://openalex.org/W2247400071","https://openalex.org/W2325935826","https://openalex.org/W2345932695","https://openalex.org/W2419646372","https://openalex.org/W2470773665","https://openalex.org/W2569009736","https://openalex.org/W7118078571"],"related_works":["https://openalex.org/W2000414283","https://openalex.org/W1494599915","https://openalex.org/W7207204159","https://openalex.org/W1519853403","https://openalex.org/W2005010294","https://openalex.org/W7096548970","https://openalex.org/W1998780882","https://openalex.org/W1995040804","https://openalex.org/W2063314706","https://openalex.org/W2062496670"],"abstract_inverted_index":{"The":[0,18],"establishment":[1],"and":[2,32,35,45,65,87,153,162,183,191,221,236,244,251],"maintenance":[3],"of":[4,13,20,30,40,53,78,81,90,132,156,158,172,203,211,231,234],"synaptic":[5,140,218,224],"connections":[6],"are":[7,180,240],"critical":[8],"for":[9,101],"the":[10,14,27,37,51,75,88,129,136,151,209,214,232],"normal":[11],"function":[12,19],"central":[15],"nervous":[16,256],"system.":[17],"mature":[21],"neural":[22,247],"circuits":[23,248],"depends":[24],"critically":[25],"on":[26,36,144],"appropriate":[28],"apposition":[29],"pre-":[31,235],"postsynaptic":[33,46,159,237],"specializations":[34],"spatial":[38,76,95,130,145],"organization":[39],"synapses":[41],"along":[42,84],"axon":[43,85],"arbors":[44],"dendrites.":[47],"In":[48,68],"neurological":[49],"disease,":[50],"integrity":[52],"these":[54,91,178,200],"processes":[55],"may":[56],"be":[57],"compromised":[58],"or":[59],"lost,":[60],"resulting":[61],"in":[62,115,169,176,186,189,208,252],"profound":[63],"cognitive":[64],"behavioral":[66],"deficits.":[67],"my":[69],"thesis":[70],"work,":[71],"I":[72,147],"have":[73,148],"investigated":[74],"distribution":[77],"functional":[79,154,246],"properties":[80,92],"presynaptic":[82,106,124],"terminals":[83],"arbor,":[86,105],"determinants":[89],"across":[93],"different":[94],"scales.":[96],"My":[97,193,226],"results":[98,194],"suggest":[99,195],"that,":[100],"a":[102],"single":[103],"axonal":[104],"strength":[107,125,141],"over":[108,121],"short":[109],"distances":[110,123],"is":[111,126],"determined":[112,127],"by":[113,128],"variations":[114],"total":[116],"vesicle":[117],"pool":[118],"size,":[119],"whereas":[120],"longer":[122],"modulation":[131],"release":[133],"fraction.":[134],"Thus":[135],"mechanisms":[137,238],"that":[138,167,184,196,239,254],"determine":[139],"differ":[142],"depending":[143],"scale.":[146],"also":[149],"examined":[150],"structural":[152],"consequences":[155],"loss":[157],"components,":[160],"NMDA":[161],"AMPA":[163],"type":[164],"glutamate":[165,204],"receptors,":[166],"occur":[168],"two":[170,201],"forms":[171],"human":[173],"autoimmune":[174],"encephalitis":[175],"which":[177],"proteins":[179],"specifically":[181],"targeted,":[182],"result":[185,207],"dramatic":[187],"deficits":[188],"cognition":[190],"behavior.":[192],"patient":[197],"antibodies":[198],"against":[199],"types":[202],"receptors":[205],"selectively":[206],"internalization":[210],"receptor":[212],"from":[213],"neuron":[215],"surface,":[216],"decreasing":[217],"localization,":[219],"currents":[220],"thus":[222],"influencing":[223],"function.":[225,258],"work":[227],"extends":[228],"our":[229],"understanding":[230],"repertoire":[233],"required":[241],"to":[242],"establish":[243],"maintain":[245],"during":[249],"development":[250],"diseases":[253],"compromise":[255],"system":[257]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2016-06-24T00:00:00"}