{"id":"https://openalex.org/W1573150583","doi":"https://doi.org/10.5772/54328","title":"Hypothyroidism, Fertility and Pregnancy","display_name":"Hypothyroidism, Fertility and Pregnancy","publication_year":2013,"publication_date":"2013-02-13","ids":{"openalex":"https://openalex.org/W1573150583","doi":"https://doi.org/10.5772/54328","mag":"1573150583"},"language":"en","primary_location":{"id":"doi:10.5772/54328","doi":"https://doi.org/10.5772/54328","is_oa":true,"landing_page_url":"https://doi.org/10.5772/54328","pdf_url":"https://www.intechopen.com/citation-pdf-url/42440","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Hypothyroidism with Focus on Development","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2485844572","display_name":"Current Topics in Hypothyroidism with Focus on Development"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.intechopen.com/citation-pdf-url/42440","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046629763","display_name":"Piergiorgio Stortoni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piergiorgio Stortoni","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111966871","display_name":"Laura Andrea","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrea L.","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.12269327,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11728","display_name":"Thyroid and Parathyroid Surgery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.9359999895095825},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.953000009059906},{"id":"https://openalex.org/keywords/fertility","display_name":"fertility","score":0.8930000066757202},{"id":"https://openalex.org/keywords/subclinical-hypothyroidism","display_name":"subclinical hypothyroidism","score":0.9039999842643738},{"id":"https://openalex.org/keywords/iodine-deficiency","display_name":"iodine deficiency","score":0.843999981880188},{"id":"https://openalex.org/keywords/thyroid-gland-size","display_name":"thyroid gland size","score":0.7049999833106995},{"id":"https://openalex.org/keywords/autoimmune-thyroiditis","display_name":"autoimmune thyroiditis","score":0.9890000224113464},{"id":"https://openalex.org/keywords/central-hypothyroidism","display_name":"central hypothyroidism","score":0.8130000233650208},{"id":"https://openalex.org/keywords/drug-induced-hypothyroidism","display_name":"drug-induced hypothyroidism","score":0.8040000200271606},{"id":"https://openalex.org/keywords/phenytoin","display_name":"phenytoin","score":0.8230000138282776},{"id":"https://openalex.org/keywords/rifampicin","display_name":"rifampicin","score":0.996999979019165}],"concepts":[{"id":"https://openalex.org/C518429986","wikidata":"https://www.wikidata.org/wiki/Q964401","display_name":"Fertility","level":3,"score":0.6806763410568237},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5327627062797546},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.47863808274269104},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39960363507270813},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09784337878227234},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.07264098525047302},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.059522926807403564},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.5772/54328","doi":"https://doi.org/10.5772/54328","is_oa":true,"landing_page_url":"https://doi.org/10.5772/54328","pdf_url":"https://www.intechopen.com/citation-pdf-url/42440","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Hypothyroidism with Focus on Development","raw_type":"book-chapter"},{"id":"pmh:oai:biblioboard.com:4c389f65-691d-4ede-88f8-c41772e74e8a","doi":null,"is_oa":true,"landing_page_url":"https://openresearchlibrary.org/viewer/4c389f65-691d-4ede-88f8-c41772e74e8a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401131","display_name":"BiblioBoard Library Catalog (Open Research Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"MODID-6d55e02e354:IntechOpen","raw_type":"CHAPTER"},{"id":"pmh:oai:intechopen.com:42440","doi":null,"is_oa":true,"landing_page_url":"http://www.intechopen.com/articles/show/title/hypothyroidism-fertility-and-pregnancy","pdf_url":null,"source":{"id":"https://openalex.org/S4306401291","display_name":"Contact-less Assessment of In-vivo Body Signals Using Microwave Doppler Radar (InTech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210154139","host_organization_name":"Intech (Slovakia)","host_organization_lineage":["https://openalex.org/I4210154139"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.intechopen.com/download/pdf/pdfs_id/42440","raw_type":"01"}],"best_oa_location":{"id":"doi:10.5772/54328","doi":"https://doi.org/10.5772/54328","is_oa":true,"landing_page_url":"https://doi.org/10.5772/54328","pdf_url":"https://www.intechopen.com/citation-pdf-url/42440","source":{"id":"https://openalex.org/S4306463447","display_name":"InTech eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Topics in Hypothyroidism with Focus on Development","raw_type":"book-chapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1573150583.pdf","grobid_xml":"https://content.openalex.org/works/W1573150583.grobid-xml"},"referenced_works_count":167,"referenced_works":["https://openalex.org/W3947919","https://openalex.org/W236687363","https://openalex.org/W1582106459","https://openalex.org/W1585384248","https://openalex.org/W1589270353","https://openalex.org/W1589308976","https://openalex.org/W1743169853","https://openalex.org/W1918799648","https://openalex.org/W1939961415","https://openalex.org/W1963307369","https://openalex.org/W1964693382","https://openalex.org/W1965714008","https://openalex.org/W1968156993","https://openalex.org/W1969473426","https://openalex.org/W1971359230","https://openalex.org/W1974084545","https://openalex.org/W1975368188","https://openalex.org/W1977677577","https://openalex.org/W1979170509","https://openalex.org/W1983261536","https://openalex.org/W1983381211","https://openalex.org/W1984273763","https://openalex.org/W1985780605","https://openalex.org/W1986432079","https://openalex.org/W1987005925","https://openalex.org/W1987184305","https://openalex.org/W1988609240","https://openalex.org/W1990948205","https://openalex.org/W1991332383","https://openalex.org/W1992128077","https://openalex.org/W1992657280","https://openalex.org/W1992874499","https://openalex.org/W1993076014","https://openalex.org/W1995533792","https://openalex.org/W1996364777","https://openalex.org/W1998528306","https://openalex.org/W2006356567","https://openalex.org/W2006947222","https://openalex.org/W2007123832","https://openalex.org/W2009081292","https://openalex.org/W2009812444","https://openalex.org/W2009905473","https://openalex.org/W2013694468","https://openalex.org/W2014042492","https://openalex.org/W2015079707","https://openalex.org/W2016236854","https://openalex.org/W2017413331","https://openalex.org/W2021680265","https://openalex.org/W2021818691","https://openalex.org/W2023829594","https://openalex.org/W2026537937","https://openalex.org/W2026844201","https://openalex.org/W2030300285","https://openalex.org/W2030307223","https://openalex.org/W2034596928","https://openalex.org/W2034766558","https://openalex.org/W2042227130","https://openalex.org/W2046236990","https://openalex.org/W2047227045","https://openalex.org/W2050391058","https://openalex.org/W2052257773","https://openalex.org/W2053632647","https://openalex.org/W2053696952","https://openalex.org/W2053975790","https://openalex.org/W2054196341","https://openalex.org/W2059483852","https://openalex.org/W2063665472","https://openalex.org/W2066397765","https://openalex.org/W2072031944","https://openalex.org/W2072296336","https://openalex.org/W2076612400","https://openalex.org/W2076702065","https://openalex.org/W2076847992","https://openalex.org/W2079039990","https://openalex.org/W2082690628","https://openalex.org/W2083223154","https://openalex.org/W2084016223","https://openalex.org/W2084311281","https://openalex.org/W2087748886","https://openalex.org/W2088262036","https://openalex.org/W2090456883","https://openalex.org/W2098589970","https://openalex.org/W2099083365","https://openalex.org/W2102866812","https://openalex.org/W2104607571","https://openalex.org/W2106227634","https://openalex.org/W2107858485","https://openalex.org/W2107997370","https://openalex.org/W2109194392","https://openalex.org/W2113514236","https://openalex.org/W2116892060","https://openalex.org/W2118928433","https://openalex.org/W2120959653","https://openalex.org/W2121667230","https://openalex.org/W2122186097","https://openalex.org/W2124173888","https://openalex.org/W2124221440","https://openalex.org/W2124475318","https://openalex.org/W2125320223","https://openalex.org/W2127830127","https://openalex.org/W2128705643","https://openalex.org/W2129072480","https://openalex.org/W2129108068","https://openalex.org/W2129328330","https://openalex.org/W2130091627","https://openalex.org/W2130354354","https://openalex.org/W2130764231","https://openalex.org/W2134916090","https://openalex.org/W2135834945","https://openalex.org/W2136197945","https://openalex.org/W2137130997","https://openalex.org/W2138527530","https://openalex.org/W2139446579","https://openalex.org/W2139932592","https://openalex.org/W2140120505","https://openalex.org/W2143794631","https://openalex.org/W2144432321","https://openalex.org/W2144980336","https://openalex.org/W2146656360","https://openalex.org/W2146916553","https://openalex.org/W2148425208","https://openalex.org/W2148541996","https://openalex.org/W2148883945","https://openalex.org/W2152763238","https://openalex.org/W2154095781","https://openalex.org/W2154116297","https://openalex.org/W2154746345","https://openalex.org/W2157641854","https://openalex.org/W2159107533","https://openalex.org/W2160393206","https://openalex.org/W2160955295","https://openalex.org/W2161108213","https://openalex.org/W2161974364","https://openalex.org/W2161982303","https://openalex.org/W2164142035","https://openalex.org/W2164480428","https://openalex.org/W2164729640","https://openalex.org/W2168576465","https://openalex.org/W2169266667","https://openalex.org/W2169627280","https://openalex.org/W2170946408","https://openalex.org/W2170968697","https://openalex.org/W2170972205","https://openalex.org/W2171019617","https://openalex.org/W2314414681","https://openalex.org/W2318484312","https://openalex.org/W2322189163","https://openalex.org/W2322561651","https://openalex.org/W2323367390","https://openalex.org/W2324123706","https://openalex.org/W2334882251","https://openalex.org/W2409954508","https://openalex.org/W2414295271","https://openalex.org/W2419612314","https://openalex.org/W2426336637","https://openalex.org/W2498279486","https://openalex.org/W2968929641","https://openalex.org/W3021125997","https://openalex.org/W3025628770","https://openalex.org/W3144091833","https://openalex.org/W4230045132","https://openalex.org/W4236512733","https://openalex.org/W4240888037","https://openalex.org/W4250013999","https://openalex.org/W4250296874","https://openalex.org/W4251374559","https://openalex.org/W4254828236"],"related_works":["https://openalex.org/W2989613256","https://openalex.org/W4224598143","https://openalex.org/W4242090654","https://openalex.org/W1034390861","https://openalex.org/W3200579667","https://openalex.org/W337181137","https://openalex.org/W2096092364","https://openalex.org/W4411164874","https://openalex.org/W7203585334","https://openalex.org/W4410761792"],"abstract_inverted_index":{"Pregnancy":[0],"has":[1,18],"a":[2],"profound":[3],"effect":[4],"on":[5],"the":[6,15,33,65,88,98,113],"thyroid":[7,100,107,114,118,142],"gland":[8,16,34],"and":[9,27,54,71,131,137],"its":[10],"function.":[11],"In":[12],"iodine-replete":[13],"countries,":[14],"size":[17,35],"been":[19],"found":[20],"to":[21,48],"increase":[22],"by":[23,37],"10%":[24],"during":[25,44,83],"pregnancy,":[26,84],"in":[28],"areas":[29],"of":[30,41,64,68,80,112],"iodine":[31,60],"deficiency,":[32],"increases":[36],"20%\u201340%.":[38],"The":[39],"prevalence":[40],"hypothyroid\u2010":[42],"ism":[43],"pregnancy":[45],"is":[46],"estimated":[47],"be":[49],"0.3\u20130.5%":[50],"for":[51,56],"overt":[52,70],"hypothyroidism":[53],"2\u20133%":[55],"subclinical":[57,72],"hypothyroidism.":[58,73],"Worldwide,":[59],"deficiency":[61],"remains":[62],"one":[63],"leading":[66],"causes":[67,79,96],"both":[69],"However,":[74],"there":[75],"are":[76],"many":[77],"other":[78],"hy\u2010":[81,126],"pothyroidism":[82],"including":[85,124],"autoimmune":[86],"thyroiditis,":[87],"most":[89],"common":[90],"or\u2010":[91],"ganic":[92],"pathology":[93],"[1].":[94],"Other":[95],"include":[97],"following:":[99],"radioiodine":[101],"ablation":[102],"(to":[103],"treat":[104],"hyperthyroidism":[105],"or":[106,128],"cancer),":[108],"hypoplasia":[109],"and/or":[110],"agenesis":[111],"gland,":[115],"surgery":[116],"(for":[117],"tumors":[119],"and,":[120],"rarely,":[121],"central":[122],"hypothyroidism,":[123],"lymphocytic":[125],"pophysitis":[127],"ectopic":[129],"thyroid)":[130],"some":[132],"drugs,":[133],"such":[134],"as":[135],"rifampin":[136],"phenytoin,":[138],"which":[139],"can":[140],"alter":[141],"metabolism":[143],"[2].":[144]},"counts_by_year":[{"year":2018,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}