{"id":"https://openalex.org/W1570488451","doi":"https://doi.org/10.1016/s0076-6879(06)10021-x","title":"[21] Mapping Histone Modifications by Nucleosome Immunoprecipitation","display_name":"[21] Mapping Histone Modifications by Nucleosome Immunoprecipitation","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1570488451","doi":"https://doi.org/10.1016/s0076-6879(06)10021-x","mag":"1570488451","pmid":"https://pubmed.ncbi.nlm.nih.gov/16938564"},"language":"en","primary_location":{"id":"doi:10.1016/s0076-6879(06)10021-x","doi":"https://doi.org/10.1016/s0076-6879(06)10021-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0076-6879(06)10021-x","pdf_url":null,"source":{"id":"https://openalex.org/S182211142","display_name":"Methods in enzymology on CD-ROM/Methods in enzymology","issn_l":"0076-6879","issn":["0076-6879","1079-2376","1557-7988"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Enzymology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4256282475","display_name":"DNA Microarrays, Part A: Array Platforms and Wet-Bench Protocols"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101762359","display_name":"David J. Clark","orcid":"https://orcid.org/0000-0002-1741-9516","observed_orcids":["https://orcid.org/0000-0002-1741-9516"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210144228","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J Clark","raw_affiliation_strings":["Laboratory of Molecular Growth Regulation, NICHD, National Institutes of Health, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Molecular Growth Regulation, NICHD, National Institutes of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210144228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056616436","display_name":"Chang-Hui Shen","orcid":"https://orcid.org/0000-0001-8510-448X","observed_orcids":["https://orcid.org/0000-0001-8510-448X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chang-Hui Shen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.984,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.95624942,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"410","issue":null,"first_page":"416","last_page":"430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":0.9700000286102295},{"id":"https://openalex.org/keywords/histone-code","display_name":"histone code","score":0.8330000042915344},{"id":"https://openalex.org/keywords/nucleosome-core-particle","display_name":"nucleosome core particle","score":0.7490000128746033},{"id":"https://openalex.org/keywords/minichromosomes","display_name":"minichromosomes","score":0.8730000257492065},{"id":"https://openalex.org/keywords/micrococcal-nuclease-digestion","display_name":"micrococcal nuclease digestion","score":0.9340000152587891},{"id":"https://openalex.org/keywords/nucleosome-mapping","display_name":"nucleosome mapping","score":0.6949999928474426},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.6740000247955322},{"id":"https://openalex.org/keywords/post-translational-modification","display_name":"post-translational modification","score":0.8399999737739563}],"concepts":[{"id":"https://openalex.org/C139024627","wikidata":"https://www.wikidata.org/wiki/Q4293132","display_name":"Micrococcal nuclease","level":5,"score":0.8776974678039551},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.8353570103645325},{"id":"https://openalex.org/C71829478","wikidata":"https://www.wikidata.org/wiki/Q901305","display_name":"Immunoprecipitation","level":3,"score":0.7357974052429199},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.6245958805084229},{"id":"https://openalex.org/C10058791","wikidata":"https://www.wikidata.org/wiki/Q910897","display_name":"Histone code","level":5,"score":0.5215077996253967},{"id":"https://openalex.org/C134320426","wikidata":"https://www.wikidata.org/wiki/Q901026","display_name":"Chromatin immunoprecipitation","level":5,"score":0.5024716854095459},{"id":"https://openalex.org/C173681060","wikidata":"https://www.wikidata.org/wiki/Q5773169","display_name":"Histone octamer","level":5,"score":0.4686291515827179},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4581299424171448},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.43210411071777344},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4294695556163788},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4098415970802307},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.38893985748291016},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3859115242958069},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.35010647773742676},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3235996663570404},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24962356686592102},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.11243170499801636},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.0815613865852356}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006657","descriptor_name":"Histones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009707","descriptor_name":"Nucleosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020411","descriptor_name":"Oligonucleotide Array Sequence Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D047369","descriptor_name":"Chromatin Immunoprecipitation","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0076-6879(06)10021-x","doi":"https://doi.org/10.1016/s0076-6879(06)10021-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0076-6879(06)10021-x","pdf_url":null,"source":{"id":"https://openalex.org/S182211142","display_name":"Methods in enzymology on CD-ROM/Methods in enzymology","issn_l":"0076-6879","issn":["0076-6879","1079-2376","1557-7988"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Enzymology","raw_type":"book-chapter"},{"id":"pmid:16938564","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16938564","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in enzymology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3154549811","display_name":"Functional characterization of remodeling complex Ino80p","funder_award_id":"R15GM067730","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G4479026908","display_name":null,"funder_award_id":"1R15 GM 67730-01","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6203909460","display_name":null,"funder_award_id":"1R15GM67730\u201001","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337393","display_name":"Division of Chemistry","ror":"https://ror.org/01ar8dr59"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1528038805","https://openalex.org/W1597695541","https://openalex.org/W1963996414","https://openalex.org/W1987901123","https://openalex.org/W1988666461","https://openalex.org/W2021220556","https://openalex.org/W2029557602","https://openalex.org/W2040375560","https://openalex.org/W2060357264","https://openalex.org/W2060866866","https://openalex.org/W2062919617","https://openalex.org/W2069428708","https://openalex.org/W2095325933","https://openalex.org/W2099826949","https://openalex.org/W2114803986","https://openalex.org/W2132619798","https://openalex.org/W2141017467","https://openalex.org/W2148168073","https://openalex.org/W2159696651","https://openalex.org/W2163585426","https://openalex.org/W2576734941"],"related_works":["https://openalex.org/W2419272494","https://openalex.org/W161291816","https://openalex.org/W7098621535","https://openalex.org/W2012124466","https://openalex.org/W3054530020","https://openalex.org/W2158948026","https://openalex.org/W1986923861","https://openalex.org/W3023275368","https://openalex.org/W3192380718","https://openalex.org/W2552641447"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}