{"id":"https://openalex.org/W1569801569","doi":"https://doi.org/10.1240/sav_gbm_2008_m_002129","title":"A flexible, high-density array platform for genome-wide characterization of epigenetic and transcriptional regulatory mechanisms involved in cancer","display_name":"A flexible, high-density array platform for genome-wide characterization of epigenetic and transcriptional regulatory mechanisms involved in cancer","publication_year":2008,"publication_date":"2008-03-01","ids":{"openalex":"https://openalex.org/W1569801569","doi":"https://doi.org/10.1240/sav_gbm_2008_m_002129","mag":"1569801569"},"language":"en","primary_location":{"id":"doi:10.1240/sav_gbm_2008_m_002129","doi":"https://doi.org/10.1240/sav_gbm_2008_m_002129","is_oa":false,"landing_page_url":"http://doi.org/10.1240/sav_gbm_2008_m_002129","pdf_url":null,"source":{"id":"https://openalex.org/S4306511173","display_name":"GBM Annual Spring meeting Mosbach 2008","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"GBM Annual Spring meeting Mosbach 2008","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020174072","display_name":"Luke O. Dannenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Luke Dannenberg","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071847481","display_name":"Leo Iniguez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Leo Iniguez","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080736495","display_name":"H. Holster","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Heather Holster","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083201945","display_name":"Peggy Farnham","orcid":"https://orcid.org/0000-0003-4469-7914","observed_orcids":["https://orcid.org/0000-0003-4469-7914"]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Peggy Farnham","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073855965","display_name":"Bing Ren","orcid":"https://orcid.org/0000-0002-5435-1127","observed_orcids":["https://orcid.org/0000-0002-5435-1127","https://orcid.org/0009-0002-3454-085X","https://orcid.org/0009-0004-0708-2069"]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bing Ren","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":null,"display_name":"David Fisher","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"David Fisher","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048312997","display_name":"Gerd P. Pfeifer","orcid":"https://orcid.org/0000-0002-5080-9604","observed_orcids":["https://orcid.org/0000-0002-5080-9604"]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Gerd Pfeifer","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387609","display_name":"Hui Liu","orcid":"https://orcid.org/0000-0002-7669-9386","observed_orcids":["https://orcid.org/0000-0002-7669-9386","https://orcid.org/0000-0002-7173-1420","https://orcid.org/0000-0003-2200-0063","https://orcid.org/0009-0007-8893-5124","https://orcid.org/0000-0001-5227-3164"]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090487130","display_name":"Jacob Otto Kitzman","orcid":"https://orcid.org/0000-0002-6145-882X","observed_orcids":["https://orcid.org/0000-0002-6145-882X"]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Jacob Kitzman","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026875517","display_name":"Fatih Ozsolak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I196064397","display_name":"Ludwig Cancer Research","ror":"https://ror.org/05923xh51","country_code":"BE","type":"nonprofit","lineage":["https://openalex.org/I196064397","https://openalex.org/I4210150094"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Fatih Ozsolak","raw_affiliation_strings":["Ludwig Cancer Research, Brussels, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ludwig Cancer Research, Brussels, Belgium","institution_ids":["https://openalex.org/I196064397"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I196064397"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07205104,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2008","issue":"Spring","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.6098999977111816,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.6098999977111816,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.3418000042438507,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.01889999955892563,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7919999957084656},{"id":"https://openalex.org/keywords/histone-modifications","display_name":"histone modifications","score":0.9800000190734863},{"id":"https://openalex.org/keywords/transcription-factor-binding","display_name":"transcription factor binding","score":0.9100000262260437},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.7609999775886536},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.7599999904632568},{"id":"https://openalex.org/keywords/photolithography","display_name":"photolithography","score":0.8899999856948853},{"id":"https://openalex.org/keywords/digital-micromirror-device","display_name":"digital micromirror device","score":0.9639999866485596},{"id":"https://openalex.org/keywords/chromatin-structure","display_name":"chromatin structure","score":0.9509999752044678},{"id":"https://openalex.org/keywords/genome-wide-characterization","display_name":"genome-wide characterization","score":0.5879999995231628}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.7254845499992371},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6435710191726685},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.6314085721969604},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.5582249164581299},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5205082297325134},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.48792359232902527},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4847121238708496},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.46576976776123047},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.44390738010406494},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4392533004283905},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.4350253939628601},{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.4316934645175934},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.430015504360199},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.35512596368789673},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2935059368610382},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2927653193473816}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1240/sav_gbm_2008_m_002129","doi":"https://doi.org/10.1240/sav_gbm_2008_m_002129","is_oa":false,"landing_page_url":"http://doi.org/10.1240/sav_gbm_2008_m_002129","pdf_url":null,"source":{"id":"https://openalex.org/S4306511173","display_name":"GBM Annual Spring meeting Mosbach 2008","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"GBM Annual Spring meeting Mosbach 2008","raw_type":"journal-article"},{"id":"mag:1569801569","doi":null,"is_oa":false,"landing_page_url":"http://clincancerres.aacrjournals.org/content/13/22_Supplement/A71","pdf_url":null,"source":{"id":"https://openalex.org/S183149254","display_name":"Clinical Cancer Research","issn_l":"1078-0432","issn":["1078-0432","1557-3265"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320273","host_organization_name":"American Association for Cancer Research","host_organization_lineage":["https://openalex.org/P4310320273"],"host_organization_lineage_names":["American Association for Cancer Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Clinical Cancer Research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8560000061988831,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2795349619","https://openalex.org/W2329888282","https://openalex.org/W2385873322","https://openalex.org/W2361062015","https://openalex.org/W1492519836","https://openalex.org/W2162871183","https://openalex.org/W2617193384","https://openalex.org/W2423250602","https://openalex.org/W66109052","https://openalex.org/W4323255626"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2016-06-24T00:00:00"}