{"id":"https://openalex.org/W1567167887","doi":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","title":"Prophage Curing in Lactobacillus casei by Isolation of a Thermoinducible Mutant","display_name":"Prophage Curing in Lactobacillus casei by Isolation of a Thermoinducible Mutant","publication_year":1982,"publication_date":"1982-06-01","ids":{"openalex":"https://openalex.org/W1567167887","doi":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","mag":"1567167887","pmid":"https://pubmed.ncbi.nlm.nih.gov/16346028","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/244228"},"language":"en","primary_location":{"id":"doi:10.1128/aem.43.6.1284-1287.1982","doi":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/244228","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068043083","display_name":"Mariko Shimizu-Kadota","orcid":"https://orcid.org/0000-0003-1050-1207","observed_orcids":["https://orcid.org/0000-0003-1050-1207","https://orcid.org/0009-0000-7298-5150"]},"institutions":[{"id":"https://openalex.org/I4210153337","display_name":"Yakult Central Institute","ror":"https://ror.org/04gcc2383","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210153337"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mariko Shimizu-Kadota","raw_affiliation_strings":["Yakult Central Institute for Microbiological Research, Tokyo, 186, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yakult Central Institute for Microbiological Research, Tokyo, 186, Japan","institution_ids":["https://openalex.org/I4210153337"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113486183","display_name":"Toshizo Sakurai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153337","display_name":"Yakult Central Institute","ror":"https://ror.org/04gcc2383","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210153337"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshizo Sakurai","raw_affiliation_strings":["Yakult Central Institute for Microbiological Research, Tokyo, 186, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yakult Central Institute for Microbiological Research, Tokyo, 186, Japan","institution_ids":["https://openalex.org/I4210153337"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210153337"],"apc_list":null,"apc_paid":null,"fwci":0.8711,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.69190871,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"43","issue":"6","first_page":"1284","last_page":"1287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10120","display_name":"Bacterial Genetics and Biotechnology","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lacticaseibacillus-casei","display_name":"Lactobacillus casei","score":0.9990000128746033},{"id":"https://openalex.org/keywords/prophages","display_name":"prophages","score":0.6769999861717224},{"id":"https://openalex.org/keywords/lysogeny","display_name":"lysogeny","score":0.7139999866485596},{"id":"https://openalex.org/keywords/heat-induction","display_name":"heat induction","score":0.718999981880188},{"id":"https://openalex.org/keywords/industrial-fermentation","display_name":"industrial fermentation","score":0.6970000267028809},{"id":"https://openalex.org/keywords/mutagenesis","display_name":"mutagenesis","score":0.8270000219345093}],"concepts":[{"id":"https://openalex.org/C73445445","wikidata":"https://www.wikidata.org/wiki/Q1712327","display_name":"Prophage","level":5,"score":0.9748141765594482},{"id":"https://openalex.org/C136199206","wikidata":"https://www.wikidata.org/wiki/Q1148110","display_name":"Lysogenic cycle","level":5,"score":0.8662745952606201},{"id":"https://openalex.org/C48292096","wikidata":"https://www.wikidata.org/wiki/Q6710264","display_name":"Lysogen","level":5,"score":0.8618444204330444},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.712529182434082},{"id":"https://openalex.org/C2776662696","wikidata":"https://www.wikidata.org/wiki/Q139777","display_name":"Lactobacillus casei","level":3,"score":0.7047941088676453},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.7010737061500549},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5727930068969727},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5655872225761414},{"id":"https://openalex.org/C197480550","wikidata":"https://www.wikidata.org/wiki/Q1258111","display_name":"Temperateness","level":5,"score":0.5170727372169495},{"id":"https://openalex.org/C2778022156","wikidata":"https://www.wikidata.org/wiki/Q576145","display_name":"Strain (injury)","level":2,"score":0.4682047963142395},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.42384248971939087},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3033312261104584},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.3000977635383606},{"id":"https://openalex.org/C2776441376","wikidata":"https://www.wikidata.org/wiki/Q165028","display_name":"Bacteriophage","level":4,"score":0.29830431938171387},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.174041748046875},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1328488290309906},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1128/aem.43.6.1284-1287.1982","doi":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","is_oa":false,"landing_page_url":"https://doi.org/10.1128/aem.43.6.1284-1287.1982","pdf_url":null,"source":{"id":"https://openalex.org/S158228368","display_name":"Applied and Environmental Microbiology","issn_l":"0099-2240","issn":["0099-2240","1070-6291","1098-5336"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and Environmental Microbiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:244228","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/244228","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Appl Environ Microbiol","raw_type":"Text"},{"id":"pmid:16346028","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16346028","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Applied and environmental microbiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:244228","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/244228","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Appl Environ Microbiol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W95850086","https://openalex.org/W335476973","https://openalex.org/W1541327799","https://openalex.org/W1602902181","https://openalex.org/W1636342640","https://openalex.org/W1930070076","https://openalex.org/W2009862212","https://openalex.org/W2051011499","https://openalex.org/W2057866584","https://openalex.org/W2088591828","https://openalex.org/W2120893243","https://openalex.org/W2138907801"],"related_works":["https://openalex.org/W271604403","https://openalex.org/W1602902181","https://openalex.org/W7001170476","https://openalex.org/W2056125670","https://openalex.org/W4400599609","https://openalex.org/W2077685229","https://openalex.org/W3013803551","https://openalex.org/W2072614947","https://openalex.org/W2916076984","https://openalex.org/W132223818"],"abstract_inverted_index":{"To":[0],"eliminate":[1],"the":[2,49,59,67],"occurrence":[3],"of":[4,58],"virulent":[5,68],"phage":[6,69],"in":[7],"industrial":[8,75],"fermentation,":[9],"attempts":[10],"were":[11,53],"made":[12],"to":[13],"obtain":[14],"prophage-cured":[15],"derivatives":[16],"from":[17,29],"Lactobacillus":[18],"casei":[19],"lysogenic":[20],"strain":[21,31],"S-1.":[22],"A":[23],"thermoinducible":[24],"mutant":[25],"lysogen":[26],"was":[27,46],"isolated":[28],"mutagenized":[30],"S-1,":[32],"since":[33],"S-1":[34],"cannot":[35],"be":[36,72],"induced":[37],"under":[38],"laboratory":[39],"conditions.":[40],"The":[41],"mutation":[42],"responsible":[43],"for":[44,74],"thermoinducibility":[45],"located":[47],"on":[48],"prophage.":[50],"Prophage-cured":[51],"strains":[52,63],"selected":[54],"after":[55],"heat":[56],"induction":[57],"mutant.":[60],"These":[61],"cured":[62],"did":[64],"not":[65],"produce":[66],"and":[70],"should":[71],"valuable":[73],"fermentation.":[76]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}