{"id":"https://openalex.org/W156050893","doi":null,"title":"[A kinetic study on serum prolactin concentration in the thyrotropin-releasing hormone test].","display_name":"[A kinetic study on serum prolactin concentration in the thyrotropin-releasing hormone test].","publication_year":1991,"publication_date":"1991-06-01","ids":{"openalex":"https://openalex.org/W156050893","mag":"156050893","pmid":"https://pubmed.ncbi.nlm.nih.gov/1910118"},"language":"ja","primary_location":{"id":"pmid:1910118","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1910118","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kaku igaku. The Japanese journal of nuclear medicine","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101677090","display_name":"Yoko Yoshida","orcid":"https://orcid.org/0000-0001-6624-6976","observed_orcids":["https://orcid.org/0000-0001-6624-6976"]},"institutions":[{"id":"https://openalex.org/I201933988","display_name":"Kagawa University","ror":"https://ror.org/04j7mzp05","country_code":"JP","type":"education","lineage":["https://openalex.org/I201933988"]},{"id":"https://openalex.org/I4210135297","display_name":"Kagawa University Hospital","ror":"https://ror.org/033sspj46","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I201933988","https://openalex.org/I4210135297"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Yoshida","raw_affiliation_strings":["Department of Radiology, Kagawa Medical School"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Kagawa Medical School","institution_ids":["https://openalex.org/I201933988","https://openalex.org/I4210135297"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109852352","display_name":"Yukiko Kawasaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Kawasaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"N Morikawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N Morikawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"M Tanabe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Tanabe","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109767297","display_name":"Keigo Satoh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Satoh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108617967","display_name":"Toyohisa TSUKAMOTO","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Tsukamoto","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"M Nakano","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Nakano","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.018025,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"28","issue":"6","first_page":"585","last_page":"90"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.9175000190734863,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10960","display_name":"Hypothalamic control of reproductive hormones","score":0.05810000002384186,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prolactin-secretion","display_name":"prolactin secretion","score":0.8560000061988831},{"id":"https://openalex.org/keywords/thyrotropin-releasing-hormone","display_name":"thyrotropin-releasing hormone","score":0.9039999842643738},{"id":"https://openalex.org/keywords/kinetic-model","display_name":"kinetic model","score":0.656000018119812},{"id":"https://openalex.org/keywords/tsh-secretion","display_name":"TSH secretion","score":0.7760000228881836},{"id":"https://openalex.org/keywords/pituitary-hormone-regulation","display_name":"pituitary hormone regulation","score":0.5419999957084656},{"id":"https://openalex.org/keywords/young-men","display_name":"young men","score":0.7829999923706055}],"concepts":[{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.9398724436759949},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.8312466144561768},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.815332293510437},{"id":"https://openalex.org/C2776216936","wikidata":"https://www.wikidata.org/wiki/Q24726011","display_name":"Thyrotropin-releasing hormone","level":3,"score":0.7818902730941772},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.7386834025382996},{"id":"https://openalex.org/C2778758028","wikidata":"https://www.wikidata.org/wiki/Q19597582","display_name":"Immunoradiometric assay","level":3,"score":0.7382675409317017},{"id":"https://openalex.org/C4134927","wikidata":"https://www.wikidata.org/wiki/Q7671336","display_name":"TRH stimulation test","level":4,"score":0.5828576683998108},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5504856109619141},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.5273072719573975},{"id":"https://openalex.org/C3020081911","wikidata":"https://www.wikidata.org/wiki/Q3918988","display_name":"Serum concentration","level":2,"score":0.4942069351673126},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.41279852390289307},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36877524852752686}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006207","descriptor_name":"Half-Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010901","descriptor_name":"Pituitary Function Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D010903","descriptor_name":"Pituitary Gland, Anterior","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011388","descriptor_name":"Prolactin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011388","descriptor_name":"Prolactin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013973","descriptor_name":"Thyrotropin-Releasing Hormone","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015592","descriptor_name":"Immunoradiometric Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1910118","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1910118","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kaku igaku. The Japanese journal of nuclear medicine","raw_type":"Journal Article"},{"id":"mag:156050893","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1910118","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6240000128746033,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1989081434","https://openalex.org/W2413600556","https://openalex.org/W2029368407","https://openalex.org/W2907885516","https://openalex.org/W2017346632","https://openalex.org/W1991627841","https://openalex.org/W2057466848","https://openalex.org/W1606852719","https://openalex.org/W2046885457","https://openalex.org/W2091666825"],"abstract_inverted_index":{"In":[0],"order":[1],"to":[2,43,124,197],"estimate":[3],"the":[4,10,45,52,60,75,78,90,94,125,134,152,161,165,171,186],"mechanism":[5],"of":[6,31,34,54,66,77,92,96,114,139,174],"prolactin":[7,14,97,102,116,140,175],"secretion":[8,46,95,167,188],"using":[9],"kinetic":[11,39,162],"model,":[12],"serum":[13,67,101],"concentrations":[15],"in":[16,130,148],"normal":[17,135],"young":[18],"men":[19],"were":[20,179],"measured":[21,64],"by":[22],"an":[23],"immunoradiometric":[24],"assay":[25],"before":[26,49],"and":[27,50,63,74,100,176],"after":[28,51,89,168],"intravenous":[29],"administration":[30,53,91],"500":[32],"micrograms":[33],"thyrotropin-releasing":[35],"hormone":[36],"(TRH).":[37],"The":[38,111,137],"model":[40,79],"was":[41,69,80,98,104,117,128,141,183],"applied":[42],"evaluate":[44],"rate":[47],"both":[48],"TRH.":[55,169],"A":[56,82],"good":[57,149],"correlation":[58],"between":[59],"calculated":[61],"values":[62,65],"concentration":[68,103,172],"observed":[70],"(r":[71],"=":[72],"0.995);":[73],"adequacy":[76],"confirmed.":[81],"few":[83],"minutes":[84],"(1.97":[85],"+/-":[86,108,119,143],"0.57":[87],"min)":[88],"TRH,":[93],"stimulated,":[99],"maximum":[105],"at":[106,133],"12.7":[107],"2.1":[109],"min.":[110],"total":[112],"amounts":[113],"secreted":[115,129],"75.4":[118],"18.4":[120],"ng/ml,":[121],"which":[122,146,178],"corresponded":[123],"amount":[126],"that":[127,185],"4.3":[131],"hours":[132],"rate.":[136],"half-life":[138],"40.8":[142],"13.8":[144],"min,":[145],"is":[147],"agreement":[150],"with":[151,195],"previously":[153],"reported":[154,159,180],"values.":[155],"We":[156],"have":[157],"already":[158],"on":[160,164],"study":[163],"TSH":[166],"Comparing":[170],"change":[173],"TSH,":[177],"previously,":[181],"it":[182],"found":[184],"stimulated":[187],"started":[189],"almost":[190],"simultaneously,":[191],"but":[192],"lasted":[193],"longer":[194],"respect":[196],"TSH.":[198]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}