{"id":"https://openalex.org/W1559110433","doi":"https://doi.org/10.1038/nrc844","title":"Chemoprevention: an essential approach to controlling cancer","display_name":"Chemoprevention: an essential approach to controlling cancer","publication_year":2002,"publication_date":"2002-07-01","ids":{"openalex":"https://openalex.org/W1559110433","doi":"https://doi.org/10.1038/nrc844","mag":"1559110433","pmid":"https://pubmed.ncbi.nlm.nih.gov/12094240"},"language":"en","primary_location":{"id":"doi:10.1038/nrc844","doi":"https://doi.org/10.1038/nrc844","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrc844","pdf_url":null,"source":{"id":"https://openalex.org/S160464432","display_name":"Nature reviews. Cancer","issn_l":"1474-175X","issn":["1474-175X","1474-1768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Cancer","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108192090","display_name":"Michael B. Sporn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]},{"id":"https://openalex.org/I4390039337","display_name":"Dartmouth Health","ror":"https://ror.org/01pa9ed26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael B. Sporn","raw_affiliation_strings":["Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. michael.sporn@dartmouth.edu","Department of Pharmacology, Dartmouth Medical School, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Dartmouth Medical School, Hanover, New Hampshire 03755, USA. michael.sporn@dartmouth.edu","institution_ids":["https://openalex.org/I107672454"]},{"raw_affiliation_string":"Department of Pharmacology, Dartmouth Medical School, Hanover, USA","institution_ids":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059532915","display_name":"Nanjoo Suh","orcid":"https://orcid.org/0000-0002-9962-9276","observed_orcids":["https://orcid.org/0000-0002-9962-9276"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]},{"id":"https://openalex.org/I4390039337","display_name":"Dartmouth Health","ror":"https://ror.org/01pa9ed26","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nanjoo Suh","raw_affiliation_strings":["Department of Pharmacology, Dartmouth Medical School, Hanover, 03755, New Hampshire, USA","Department of Pharmacology, Dartmouth Medical School, Hanover, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, Dartmouth Medical School, Hanover, 03755, New Hampshire, USA","institution_ids":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]},{"raw_affiliation_string":"Department of Pharmacology, Dartmouth Medical School, Hanover, USA","institution_ids":["https://openalex.org/I107672454","https://openalex.org/I4390039337"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.0007,"has_fulltext":false,"cited_by_count":379,"citation_normalized_percentile":{"value":0.93327322,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"2","issue":"7","first_page":"537","last_page":"543"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.4140999913215637,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening","score":0.4140999913215637,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.07980000227689743,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13656","display_name":"Science, Research, and Medicine","score":0.0738999992609024,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemoprevention","display_name":"chemoprevention","score":0.8809999823570251},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cancer-mortality","display_name":"cancer mortality","score":0.9459999799728394},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/cancer-research-priorities","display_name":"cancer research priorities","score":0.7149999737739563},{"id":"https://openalex.org/keywords/cancer-control","display_name":"cancer control","score":0.32499998807907104}],"concepts":[{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.7369189858436584},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6750650405883789},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.529723584651947},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.42597153782844543},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4169315695762634},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2003733217716217}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008956","descriptor_name":"Models, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1038/nrc844","doi":"https://doi.org/10.1038/nrc844","is_oa":false,"landing_page_url":"https://doi.org/10.1038/nrc844","pdf_url":null,"source":{"id":"https://openalex.org/S160464432","display_name":"Nature reviews. Cancer","issn_l":"1474-175X","issn":["1474-175X","1474-1768"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Reviews Cancer","raw_type":"journal-article"},{"id":"pmid:12094240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12094240","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature reviews. Cancer","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W129461181","https://openalex.org/W261715122","https://openalex.org/W1484293540","https://openalex.org/W1508025216","https://openalex.org/W1510694680","https://openalex.org/W1518709998","https://openalex.org/W1546343584","https://openalex.org/W1548163058","https://openalex.org/W1552528612","https://openalex.org/W1565561072","https://openalex.org/W1574615823","https://openalex.org/W1576412791","https://openalex.org/W1602659612","https://openalex.org/W1617415306","https://openalex.org/W1656339735","https://openalex.org/W1749479308","https://openalex.org/W1763133597","https://openalex.org/W1848388241","https://openalex.org/W1915730962","https://openalex.org/W1936190307","https://openalex.org/W1965150594","https://openalex.org/W1969783942","https://openalex.org/W1975210552","https://openalex.org/W1977681992","https://openalex.org/W1978879532","https://openalex.org/W1985434939","https://openalex.org/W1986364825","https://openalex.org/W2002859032","https://openalex.org/W2006636734","https://openalex.org/W2007456673","https://openalex.org/W2007618242","https://openalex.org/W2009629707","https://openalex.org/W2010069724","https://openalex.org/W2015462373","https://openalex.org/W2019242560","https://openalex.org/W2021206718","https://openalex.org/W2022285476","https://openalex.org/W2026058763","https://openalex.org/W2044155146","https://openalex.org/W2044573147","https://openalex.org/W2051591296","https://openalex.org/W2051966279","https://openalex.org/W2056961869","https://openalex.org/W2072762682","https://openalex.org/W2073788205","https://openalex.org/W2077894910","https://openalex.org/W2079080809","https://openalex.org/W2082064933","https://openalex.org/W2088905899","https://openalex.org/W2090116402","https://openalex.org/W2098664089","https://openalex.org/W2101676749","https://openalex.org/W2110659960","https://openalex.org/W2114849059","https://openalex.org/W2116119855","https://openalex.org/W2116285335","https://openalex.org/W2116861117","https://openalex.org/W2117966565","https://openalex.org/W2133249365","https://openalex.org/W2134062048","https://openalex.org/W2134427365","https://openalex.org/W2141647078","https://openalex.org/W2169557427","https://openalex.org/W2170550480","https://openalex.org/W2172256092","https://openalex.org/W2262976102","https://openalex.org/W2315403385","https://openalex.org/W2317242858","https://openalex.org/W2336169581","https://openalex.org/W4236100340","https://openalex.org/W4285719527","https://openalex.org/W4297022993","https://openalex.org/W6631081250"],"related_works":["https://openalex.org/W2410242023","https://openalex.org/W4396837467","https://openalex.org/W2016424612","https://openalex.org/W7099452838","https://openalex.org/W581284734","https://openalex.org/W2396371982","https://openalex.org/W3047896694","https://openalex.org/W4252188545","https://openalex.org/W2418691654","https://openalex.org/W2043205125"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":12},{"year":2019,"cited_by_count":10},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":21},{"year":2014,"cited_by_count":18},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":23}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}