{"id":"https://openalex.org/W1556777705","doi":null,"title":"Physiological studies of whole-body hyperthermia of dogs.","display_name":"Physiological studies of whole-body hyperthermia of dogs.","publication_year":1985,"publication_date":"1985-06-01","ids":{"openalex":"https://openalex.org/W1556777705","mag":"1556777705","pmid":"https://pubmed.ncbi.nlm.nih.gov/3986808"},"language":"en","primary_location":{"id":"pmid:3986808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3986808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053688183","display_name":"Dennis W. Macy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D W Macy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043726177","display_name":"Carol Ann Macy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C A Macy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101790076","display_name":"Robert J. Scott","orcid":"https://orcid.org/0000-0001-7885-3108","observed_orcids":["https://orcid.org/0000-0001-7885-3108"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R J Scott","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060625343","display_name":"Edward L. Gillette","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E L Gillette","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113665813","display_name":"John F. Speer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J F Speer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2675,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.87327168,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"45","issue":"6","first_page":"2769","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses","score":0.951200008392334,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.03929999843239784,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12365","display_name":"Effects of Environmental Stressors on Livestock","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/whole-body-hyperthermia","display_name":"whole-body hyperthermia","score":0.9959999918937683},{"id":"https://openalex.org/keywords/core-body-temperature","display_name":"core body temperature","score":0.7419999837875366},{"id":"https://openalex.org/keywords/tachycardia","display_name":"tachycardia","score":0.8149999976158142},{"id":"https://openalex.org/keywords/tachypnea","display_name":"tachypnea","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"hypoxemia","score":0.8259999752044678},{"id":"https://openalex.org/keywords/hypercapnia","display_name":"hypercapnia","score":0.7310000061988831},{"id":"https://openalex.org/keywords/respiratory-alkalosis","display_name":"respiratory alkalosis","score":0.8029999732971191},{"id":"https://openalex.org/keywords/metabolic-acidosis","display_name":"metabolic acidosis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/anion-gap","display_name":"anion gap","score":0.9729999899864197},{"id":"https://openalex.org/keywords/serum-potassium","display_name":"serum potassium","score":0.8040000200271606},{"id":"https://openalex.org/keywords/serum-phosphorus","display_name":"serum phosphorus","score":0.9890000224113464},{"id":"https://openalex.org/keywords/blood-gases","display_name":"blood gases","score":0.5389999747276306},{"id":"https://openalex.org/keywords/dogs","display_name":"dogs","score":0.5619999766349792}],"concepts":[{"id":"https://openalex.org/C2779949491","wikidata":"https://www.wikidata.org/wiki/Q242165","display_name":"Hyperthermia","level":2,"score":0.7946871519088745},{"id":"https://openalex.org/C2781063116","wikidata":"https://www.wikidata.org/wiki/Q1969062","display_name":"Respiratory alkalosis","level":3,"score":0.7109066843986511},{"id":"https://openalex.org/C2778312941","wikidata":"https://www.wikidata.org/wiki/Q570920","display_name":"Tachypnea","level":3,"score":0.6065844893455505},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5993408560752869},{"id":"https://openalex.org/C2776989520","wikidata":"https://www.wikidata.org/wiki/Q2145935","display_name":"Respiratory acidosis","level":3,"score":0.5685145258903503},{"id":"https://openalex.org/C2778553927","wikidata":"https://www.wikidata.org/wiki/Q185089","display_name":"Acidosis","level":2,"score":0.5471951961517334},{"id":"https://openalex.org/C2777140959","wikidata":"https://www.wikidata.org/wiki/Q10343041","display_name":"pCO2","level":2,"score":0.4759509265422821},{"id":"https://openalex.org/C2777068682","wikidata":"https://www.wikidata.org/wiki/Q512654","display_name":"Alkalosis","level":3,"score":0.46899130940437317},{"id":"https://openalex.org/C2779246250","wikidata":"https://www.wikidata.org/wiki/Q1598200","display_name":"Metabolic acidosis","level":2,"score":0.4495127499103546},{"id":"https://openalex.org/C517785266","wikidata":"https://www.wikidata.org/wiki/Q703","display_name":"Potassium","level":2,"score":0.4279627799987793},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.41162213683128357},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3987354040145874},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.39351293444633484},{"id":"https://openalex.org/C2780283014","wikidata":"https://www.wikidata.org/wiki/Q209583","display_name":"Tachycardia","level":2,"score":0.33656764030456543},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.281794011592865},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001772","descriptor_name":"Blood Cell Count","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001774","descriptor_name":"Blood Chemical Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004573","descriptor_name":"Electrolytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006979","descriptor_name":"Hyperthermia, Induced","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D012119","descriptor_name":"Respiration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3986808","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3986808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},{"id":"mag:1556777705","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3986808","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8199999928474426}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W119151482","https://openalex.org/W2161799839","https://openalex.org/W2994131674","https://openalex.org/W2067791467","https://openalex.org/W1992033880","https://openalex.org/W2323819844","https://openalex.org/W2401279283","https://openalex.org/W598142619","https://openalex.org/W182137911","https://openalex.org/W2055139931"],"abstract_inverted_index":{"Whole":[0],"body":[1],"hyperthermia":[2],"to":[3],"42":[4],"degrees":[5,23],"C":[6,24],"was":[7],"induced":[8],"in":[9,27,47,73,85,93],"five":[10],"normal":[11],"beagles,":[12],"using":[13],"a":[14,65,81],"humidity-":[15],"and":[16,30,40,53,96,114],"temperature-controlled":[17],"chamber.":[18],"Core":[19],"temperatures":[20],"of":[21,61,64,76],"41.2-43.0":[22],"were":[25,98],"achieved":[26],"50":[28],"min":[29],"maintained":[31],"for":[32],"60":[33],"min.":[34],"Cardiopulmonary":[35],"responses":[36],"included":[37],"marked":[38],"tachypnea":[39],"tachycardia.":[41],"Blood":[42],"gases":[43],"underwent":[44],"progressive":[45],"drops":[46,92],"both":[48],"PO2":[49],"(mean,":[50,55],"117":[51],"torr)":[52],"PCO2":[54],"22":[56],"torr),":[57],"suggesting":[58],"the":[59,62,74,86],"possibility":[60],"development":[63],"diffusion":[66],"barrier":[67],"during":[68,101],"heating.":[69],"Increased":[70],"anion":[71],"gaps":[72],"face":[75],"respiratory":[77],"alkalosis":[78],"indicated":[79],"that":[80],"metabolic":[82],"acidosis":[83],"developed":[84],"heated":[87],"dogs.":[88],"Transient":[89],"but":[90],"significant":[91],"serum":[94,107],"potassium":[95],"phosphorus":[97],"also":[99],"observed":[100],"hyperthermia.":[102],"Other":[103],"physiological":[104],"data,":[105],"including":[106],"chemistries,":[108],"complete":[109],"blood":[110],"count,":[111],"colony-forming":[112],"units,":[113],"urine":[115],"electrolyte":[116],"excretion,":[117],"did":[118],"not":[119],"change":[120],"significantly.":[121]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}