{"id":"https://openalex.org/W1555144352","doi":null,"title":"Cardiovascular function and biomarkers in women with preeclampsia","display_name":"Cardiovascular function and biomarkers in women with preeclampsia","publication_year":2010,"publication_date":"2010-01-22","ids":{"openalex":"https://openalex.org/W1555144352","mag":"1555144352"},"language":"en","primary_location":{"id":"pmh:oai:figshare.com:article/26923417","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Cardiovascular_function_and_biomarkers_in_women_with_preeclampsia/26923417","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10616/39366","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109245741","display_name":"Rangeen Rafik Hamad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rangeen Rafik Hamad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5109245741"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10290","display_name":"Pregnancy and preeclampsia studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12464","display_name":"Neurological Complications and Syndromes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preeclampsia","display_name":"preeclampsia","score":0.9789999723434448},{"id":"https://openalex.org/keywords/cardiovascular-function","display_name":"cardiovascular function","score":0.9120000004768372},{"id":"https://openalex.org/keywords/flow-mediated-dilation","display_name":"flow-mediated dilation","score":0.7900000214576721},{"id":"https://openalex.org/keywords/endothelial-dysfunction","display_name":"endothelial dysfunction","score":0.7310000061988831},{"id":"https://openalex.org/keywords/brachial-artery","display_name":"brachial artery","score":0.7059999704360962},{"id":"https://openalex.org/keywords/left-ventricular-diastolic-function","display_name":"left ventricular diastolic function","score":0.7139999866485596},{"id":"https://openalex.org/keywords/nt-probnp","display_name":"NT-proBNP","score":0.8569999933242798},{"id":"https://openalex.org/keywords/cystatin-c","display_name":"cystatin C","score":0.9660000205039978},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.8999999761581421},{"id":"https://openalex.org/keywords/thrombin-generation","display_name":"thrombin generation","score":0.6980000138282776},{"id":"https://openalex.org/keywords/platelet-microparticles","display_name":"platelet microparticles","score":0.9369999766349792},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8050000071525574},{"id":"https://openalex.org/keywords/pentraxin-3","display_name":"pentraxin 3","score":0.7490000128746033},{"id":"https://openalex.org/keywords/sflt-1-plgf-ratio","display_name":"sFlt-1/PlGF ratio","score":0.7770000100135803},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.5189999938011169},{"id":"https://openalex.org/keywords/postpartum-follow-up","display_name":"postpartum follow-up","score":0.5519999861717224}],"concepts":[{"id":"https://openalex.org/C2777218350","wikidata":"https://www.wikidata.org/wiki/Q61335","display_name":"Preeclampsia","level":3,"score":0.77027428150177},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5001943111419678},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4996151924133301},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38664811849594116},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.20889025926589966},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20812737941741943},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08479040861129761}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:figshare.com:article/26923417","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Cardiovascular_function_and_biomarkers_in_women_with_preeclampsia/26923417","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"pmh:oai:openarchive.ki.se:10616/39366","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39366","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1555144352","doi":null,"is_oa":false,"landing_page_url":"https://openarchive.ki.se/xmlui/bitstream/10616/39366/1/thesis.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:openarchive.ki.se:10616/39366","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10616/39366","pdf_url":null,"source":{"id":"https://openalex.org/S4306400147","display_name":"Open Archive (Karolinska Institutet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28166907","host_organization_name":"Karolinska Institutet","host_organization_lineage":["https://openalex.org/I28166907"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":132,"referenced_works":["https://openalex.org/W92189825","https://openalex.org/W1479945039","https://openalex.org/W1577579821","https://openalex.org/W1606843604","https://openalex.org/W1926780910","https://openalex.org/W1963769482","https://openalex.org/W1965696160","https://openalex.org/W1965728993","https://openalex.org/W1965892323","https://openalex.org/W1966510884","https://openalex.org/W1968382510","https://openalex.org/W1969388136","https://openalex.org/W1969665146","https://openalex.org/W1971252664","https://openalex.org/W1973905104","https://openalex.org/W1975659483","https://openalex.org/W1975714739","https://openalex.org/W1977859686","https://openalex.org/W1978113398","https://openalex.org/W1978635975","https://openalex.org/W1979017126","https://openalex.org/W1979175932","https://openalex.org/W1980421688","https://openalex.org/W1983186128","https://openalex.org/W1984970610","https://openalex.org/W1985413462","https://openalex.org/W1986122868","https://openalex.org/W1986480139","https://openalex.org/W1988319525","https://openalex.org/W1989884721","https://openalex.org/W1991959440","https://openalex.org/W2003537960","https://openalex.org/W2004453285","https://openalex.org/W2005042579","https://openalex.org/W2009928277","https://openalex.org/W2010733383","https://openalex.org/W2011786812","https://openalex.org/W2017269547","https://openalex.org/W2019486375","https://openalex.org/W2023700938","https://openalex.org/W2027435767","https://openalex.org/W2029094459","https://openalex.org/W2030889295","https://openalex.org/W2031905534","https://openalex.org/W2032133259","https://openalex.org/W2035032363","https://openalex.org/W2035307313","https://openalex.org/W2035953264","https://openalex.org/W2041999129","https://openalex.org/W2042037450","https://openalex.org/W2042040515","https://openalex.org/W2043180278","https://openalex.org/W2043787753","https://openalex.org/W2044625807","https://openalex.org/W2044805923","https://openalex.org/W2045250719","https://openalex.org/W2045838083","https://openalex.org/W2047277409","https://openalex.org/W2051159313","https://openalex.org/W2053109048","https://openalex.org/W2055154290","https://openalex.org/W2057443385","https://openalex.org/W2057792005","https://openalex.org/W2059277748","https://openalex.org/W2060264217","https://openalex.org/W2062082106","https://openalex.org/W2063207032","https://openalex.org/W2064872416","https://openalex.org/W2066405267","https://openalex.org/W2067034277","https://openalex.org/W2067833381","https://openalex.org/W2070110584","https://openalex.org/W2073872087","https://openalex.org/W2075067207","https://openalex.org/W2076227731","https://openalex.org/W2078023575","https://openalex.org/W2080696902","https://openalex.org/W2081255404","https://openalex.org/W2081734842","https://openalex.org/W2083473113","https://openalex.org/W2084147283","https://openalex.org/W2084757096","https://openalex.org/W2085428278","https://openalex.org/W2087432278","https://openalex.org/W2088151971","https://openalex.org/W2089891103","https://openalex.org/W2094462113","https://openalex.org/W2095582349","https://openalex.org/W2095982855","https://openalex.org/W2096073058","https://openalex.org/W2097090662","https://openalex.org/W2097408712","https://openalex.org/W2098143325","https://openalex.org/W2103184834","https://openalex.org/W2103244450","https://openalex.org/W2104822516","https://openalex.org/W2110975139","https://openalex.org/W2116702282","https://openalex.org/W2119036999","https://openalex.org/W2119091661","https://openalex.org/W2122160885","https://openalex.org/W2123398886","https://openalex.org/W2126884738","https://openalex.org/W2128796674","https://openalex.org/W2130201737","https://openalex.org/W2132643733","https://openalex.org/W2132961242","https://openalex.org/W2136952545","https://openalex.org/W2137759182","https://openalex.org/W2140476817","https://openalex.org/W2142636540","https://openalex.org/W2142738495","https://openalex.org/W2143180984","https://openalex.org/W2144648204","https://openalex.org/W2147144317","https://openalex.org/W2154973585","https://openalex.org/W2155583453","https://openalex.org/W2158462543","https://openalex.org/W2158822102","https://openalex.org/W2160234571","https://openalex.org/W2160938428","https://openalex.org/W2163843680","https://openalex.org/W2164045626","https://openalex.org/W2169865118","https://openalex.org/W2171250897","https://openalex.org/W2315977226","https://openalex.org/W2334044617","https://openalex.org/W2342639549","https://openalex.org/W2419348263","https://openalex.org/W3203440974","https://openalex.org/W4365786727","https://openalex.org/W4407829081"],"related_works":["https://openalex.org/W2115094926","https://openalex.org/W2012285995","https://openalex.org/W2182659438","https://openalex.org/W2312204978","https://openalex.org/W2893512732","https://openalex.org/W1972582850","https://openalex.org/W2100242441","https://openalex.org/W2461697223","https://openalex.org/W4405456624","https://openalex.org/W1995274417"],"abstract_inverted_index":{"Background:":[0],"Preeclampsia":[1],"(PE)":[2],"is":[3,31,36,510],"a":[4,97,159,176,186,280,403,515,542],"multisystem":[5],"disorder":[6,30],"peculiar":[7],"to":[8,76,289,364],"human":[9],"pregnancy":[10,51,86,216,220,314],"and":[11,18,43,46,75,87,92,101,131,141,146,169,175,192,200,205,212,221,228,234,257,259,269,275,299,302,315,324,350,356,380,382,420,427,444,449,460,469,476,484,573,579,605],"characterized":[12],"by":[13,577],"the":[14,21,49,70,78,110,119,147,237,320,345,431,440],"onset":[15],"of":[16,24,28,57,72,80,83,99,118,124,134,149,161,179,190,236,245,283,297,358,384,405,411,418,430,451,492,544,569,588],"hypertension":[17],"proteinuria":[19],"after":[20,88,109,224,458,514],"20th":[22],"week":[23],"gestation.":[25],"The":[26,242,340],"pathophysiology":[27],"this":[29],"still":[32],"not":[33,37],"clear.":[34],"PE":[35,84,100,162,211,266,333,374,393,406,434],"only":[38],"associated":[39,436],"with":[40,54,96,158,195,210,214,265,330,337,373,390,397,402,437,467,541],"significant":[41],"maternal":[42],"fetal":[44],"morbidity":[45],"mortality":[47],"during":[48,85,153,173,198,219,313,424],"index":[50,111],"but":[52],"also":[53],"higher":[55,166,177,187,281,295,327,387],"risk":[56],"cardiovascular":[58,73,452,580],"disease":[59],"later":[60],"in":[61,69,272,328,335,344,371,388,395,439,465,481,488,539,575,609],"life.":[62],"Overall":[63],"aim:":[64],"To":[65],"study":[66],"PE-related":[67],"changes":[68],"function":[71,413,448,574,604],"system":[74],"measure":[77],"levels":[79,148,244,296],"different":[81],"biomarkers":[82],"delivery.":[89,225],"Papers":[90,203],"I":[91,256],"II:":[93],"Eighteen":[94],"women":[95,209,329,372,389,466,540],"history":[98,160,404,543],"17":[102],"age-matched":[103],"controls":[104],"were":[105,151,217,232,262,326,369,386,461,479,485],"enrolled":[106],"one":[107],"year":[108,513],"pregnancy.":[112,375],"All":[113],"underwent":[114],"non-invasive":[115],"ultrasound":[116],"examination":[117],"brachial":[120,238],"artery":[121,239],"for":[122],"evaluation":[123],"flow-mediated":[125,508],"vasodilatation":[126],"(FMD).":[127],"Ambulatory":[128],"blood":[129,243],"pressure":[130,172],"plasma":[132],"concentrations":[133],"lipoproteins,":[135],"inflammation":[136],"markers,":[137],"adhesion":[138],"molecules,":[139],"glucometabolic":[140],"hemostatic":[142],"factors,":[143],"thrombin":[144,191,537],"generation":[145,538],"microparticles":[150],"determined":[152],"specific":[154],"menstrual":[155,432],"phases.":[156,202],"Women":[157,264,401],"had":[163,185,279,407],"lower":[164,303,379],"FMD,":[165],"systolic,":[167],"diastolic":[168,286,291],"mean":[170],"arterial":[171],"daytime,":[174],"degree":[178],"insulin":[180],"resistance.":[181],"In":[182,318,472],"addition":[183],"they":[184],"total":[188],"amount":[189],"platelet-derived":[193,422],"microparticles,":[194,423],"no":[196],"variation":[197],"follicular":[199,426],"luteal":[201,428],"III":[204],"IV:":[206],"Thirty-five":[207],"pregnant":[208],"30":[213],"normal":[215],"examined":[218],"3-6":[222],"months":[223,457],"Transthoracic":[226],"echocardiography":[227,578],"Doppler":[229],"tissue":[230],"imaging":[231],"performed,":[233],"FMD":[235,341,377],"was":[240,342,378,435],"examined.":[241],"amino-terminal":[246],"pro-brain":[247],"natriuretic":[248],"peptide":[249],"(NT-pro-BNP),":[250],"C-reactive":[251],"protein,":[252],"cystatin":[253,300,310],"C,":[254,301],"troponin":[255],"inflammatory":[258,475],"angiogenic":[260],"markers":[261,478],"measured.":[263],"showed":[267],"structural":[268],"functional":[270],"alterations":[271,438,455],"left":[273,276,441,570],"ventricle":[274],"atrium.":[277],"They":[278],"ratio":[282,323,357,383],"early":[284,290],"transmitral":[285],"flow":[287],"velocity":[288,293],"myocardial":[292],"(E/E),":[294],"NT-pro-BNP":[298,325],"glomerular":[304],"filtration":[305],"rate":[306],"as":[307,414,416],"estimated":[308],"using":[309],"C":[311],"both":[312,425],"at":[316,348,351],"follow-up.":[317,352],"addition,":[319,473],"lateral":[321],"E/E":[322],"early-onset,":[331,391],"severe":[332,392,470],"than":[334,394],"those":[336,396,482],"late":[338,398],"PE.":[339,399,471,490],"decreased":[343],"preeclamptic":[346],"group":[347],"inclusion":[349],"Pentraxin":[353,607],"3":[354,608],"(PTX3)":[355],"soluble":[359],"fms-like":[360],"tyrosine":[361],"kinase-1":[362],"(sFlt-1)":[363],"placental":[365],"growth":[366],"factor":[367],"(P1GF)":[368],"elevated":[370,474,606],"Furthermore":[376],"PTX3":[381],"sFlt-1/P1GF":[385],"Conclusion:":[400],"persisting":[408],"identifiable":[409],"abnormalities":[410],"vascular":[412],"well":[415],"signs":[417],"hypercoagulability":[419],"excess":[421],"phases":[429],"cycle.":[433],"ventricular":[442,571],"structure":[443,572],"function,":[445],"impaired":[446],"endothelial":[447,603],"elevation":[450],"biomarkers.":[453],"These":[454],"persisted":[456],"delivery":[459],"more":[462],"clearly":[463],"visible":[464],"early-onset":[468,489,610],"antiangiogenic":[477],"present":[480,511],"women,":[483],"especially":[486],"pronounced":[487],"List":[491],"scientific":[493],"papers":[494],"I.":[495],"Hamad":[496,525,557,593],"RR,":[497],"Eriksson":[498,531,565,595],"MJ,":[499,596],"Silveira":[500],"A,":[501,503,560,598],"Hamsten":[502],"Bremme":[504,533,563,599],"K":[505,534,600],"(2007).":[506],"\"Decreased":[507],"dilation":[509],"1":[512],"pre-eclamptic":[516],"pregnancy.\"":[517],"J":[518,582],"Hypertens":[519,583],"25(11):":[520],"2301-7":[521],"https://pubmed.ncbi.nlm.nih.gov/17921826":[522],"II.":[523],"Rafik":[524,556,592],"R,":[526,558,594],"Curvers":[527],"J,":[528,562],"Berntorp":[529],"E,":[530],"M,":[532],"(2009).":[535,567,601],"\"Increased":[536],"preeclampsia.\"":[545,611],"Thromb":[546],"Res":[547],"123(4):":[548],"580-6.":[549],"Epub":[550,586],"2008":[551],"May":[552],"22":[553],"https://pubmed.ncbi.nlm.nih.gov/18501408":[554],"III.":[555],"Larsson":[559,597],"Pernow":[561],"K,":[564],"MJ":[566],"\"Assessment":[568],"preeclampsia":[576],"biomarkers.\"":[581],"Oct":[584],"3:":[585],"ahead":[587],"print":[589],"https://pubmed.ncbi.nlm.nih.gov/19809366":[590],"IV.":[591],"\"Impaired":[602],"(Submitted)":[612]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
