{"id":"https://openalex.org/W1554375659","doi":null,"title":"Cystic fibrosis in adults: the unsuspected pulmonary diagnosis.","display_name":"Cystic fibrosis in adults: the unsuspected pulmonary diagnosis.","publication_year":1976,"publication_date":"1976-01-24","ids":{"openalex":"https://openalex.org/W1554375659","mag":"1554375659","pmid":"https://pubmed.ncbi.nlm.nih.gov/1253048","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1956824"},"language":"en","primary_location":{"id":"pmid:1253048","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1253048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Medical Association journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1956824/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"A J Nolan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"A J Nolan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.1719,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.89402964,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"114","issue":"2","first_page":"142","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/adult-onset-cystic-fibrosis","display_name":"adult-onset cystic fibrosis","score":0.9020000100135803},{"id":"https://openalex.org/keywords/delayed-diagnosis","display_name":"delayed diagnosis","score":0.6970000267028809},{"id":"https://openalex.org/keywords/sweat-test","display_name":"sweat test","score":0.7549999952316284},{"id":"https://openalex.org/keywords/pancreatic-insufficiency","display_name":"pancreatic insufficiency","score":0.843999981880188},{"id":"https://openalex.org/keywords/bronchiectasis","display_name":"bronchiectasis","score":0.9750000238418579},{"id":"https://openalex.org/keywords/chronic-bronchitis","display_name":"chronic bronchitis","score":0.847000002861023},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.949999988079071},{"id":"https://openalex.org/keywords/genetic-counseling","display_name":"genetic counseling","score":0.906000018119812}],"concepts":[{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.8834916353225708},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8597915172576904},{"id":"https://openalex.org/C2779379686","wikidata":"https://www.wikidata.org/wiki/Q32778","display_name":"Bronchiectasis","level":3,"score":0.6805859208106995},{"id":"https://openalex.org/C2779993553","wikidata":"https://www.wikidata.org/wiki/Q173022","display_name":"Bronchitis","level":2,"score":0.6435408592224121},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5787509083747864},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5414789319038391},{"id":"https://openalex.org/C2778821649","wikidata":"https://www.wikidata.org/wiki/Q424227","display_name":"Bronchiolitis","level":3,"score":0.527013897895813},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5093849301338196},{"id":"https://openalex.org/C2992694001","wikidata":"https://www.wikidata.org/wiki/Q173022","display_name":"Chronic bronchitis","level":2,"score":0.49654537439346313},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.47414538264274597},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.4721137285232544},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.454500287771225},{"id":"https://openalex.org/C2781244666","wikidata":"https://www.wikidata.org/wiki/Q32446","display_name":"Pulmonary fibrosis","level":3,"score":0.4267148971557617},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.4115034341812134},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.39279893040657043},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.2845146656036377},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2844725251197815},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.27532094717025757}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008173","descriptor_name":"Lung Diseases, Obstructive","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012140","descriptor_name":"Respiratory Tract Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012965","descriptor_name":"Sodium Chloride","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D013542","descriptor_name":"Sweat","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:1253048","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1253048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Medical Association journal","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1956824","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1956824/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Med Assoc J","raw_type":"Text"},{"id":"mag:1554375659","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1253048","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1956824","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1956824/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can Med Assoc J","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W166969452","https://openalex.org/W1522968823","https://openalex.org/W1545793748","https://openalex.org/W1674534835","https://openalex.org/W1903134188","https://openalex.org/W1939087218","https://openalex.org/W1946951765","https://openalex.org/W1969427484","https://openalex.org/W1972677716","https://openalex.org/W1973384808","https://openalex.org/W2005805929","https://openalex.org/W2012964389","https://openalex.org/W2022818230","https://openalex.org/W2026636061","https://openalex.org/W2039930711","https://openalex.org/W2049566855","https://openalex.org/W2053531589","https://openalex.org/W2060193843","https://openalex.org/W2064148479","https://openalex.org/W2072443105","https://openalex.org/W2176144745","https://openalex.org/W2323217275","https://openalex.org/W2406399919","https://openalex.org/W2410729458","https://openalex.org/W2412982691","https://openalex.org/W2414818787","https://openalex.org/W2439843964","https://openalex.org/W2460511609"],"related_works":["https://openalex.org/W2040515029","https://openalex.org/W2324054975","https://openalex.org/W2471061618","https://openalex.org/W2014277219","https://openalex.org/W2098813726","https://openalex.org/W2054220871","https://openalex.org/W2464336261","https://openalex.org/W2020826599","https://openalex.org/W4394568979","https://openalex.org/W2018994990"],"abstract_inverted_index":{"The":[0],"clinical":[1],"spectrum":[2],"of":[3,35,47,53,59,82],"cystic":[4,83],"fibrosis":[5,84],"is":[6,76],"insufficiently":[7],"appreciated.":[8],"This":[9],"disease":[10,37,118],"may":[11],"occur":[12],"in":[13,23,55,85,88,119],"adolescents":[14],"or":[15,20],"adults":[16,87],"who":[17],"had":[18,62],"minimal":[19],"no":[21],"symptoms":[22],"childhood.":[24],"In":[25],"three":[26],"patients":[27,61],"the":[28,33,56,60,73,80,117],"diagnosis":[29,81],"was":[30,68],"made":[31],"on":[32],"basis":[34],"respiratory":[36,48,105],"(including":[38],"bronchiectasis,":[39],"pneumonia":[40],"and":[41,50,110],"chronic":[42],"bronchitis),":[43],"a":[44],"family":[45],"history":[46],"disease,":[49],"elevated":[51],"concentrations":[52],"electrolytes":[54],"sweat.":[57],"Two":[58],"pancreatic":[63],"insufficiency,":[64],"but":[65],"this":[66],"feature":[67],"not":[69,101],"considered":[70],"necessary":[71],"for":[72],"diagnosis.":[74],"It":[75],"important":[77],"to":[78,90,103,115],"make":[79],"affected":[86],"order":[89],"prescribe":[91],"appropriate":[92,112],"therapy,":[93],"avoid":[94],"unnecessary":[95],"operations,":[96],"anticipate":[97],"complications":[98],"that":[99],"are":[100],"common":[102],"other":[104],"diseases,":[106],"provide":[107],"genetic":[108],"counselling":[109],"initiate":[111],"screening":[113],"procedures":[114],"detect":[116],"close":[120],"relatives.":[121]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}