{"id":"https://openalex.org/W155407483","doi":"https://doi.org/10.1007/978-1-4612-4584-1_16","title":"Effects of Cu-Dips on Ischemia-Reperfusion Injury","display_name":"Effects of Cu-Dips on Ischemia-Reperfusion Injury","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W155407483","doi":"https://doi.org/10.1007/978-1-4612-4584-1_16","mag":"155407483"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4612-4584-1_16","doi":"https://doi.org/10.1007/978-1-4612-4584-1_16","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-4584-1_16","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Copper Complexes","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W617102512","display_name":"Biology of Copper Complexes"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004155555","display_name":"Lucrecia A. Hernandez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83809506","display_name":"University of South Alabama","ror":"https://ror.org/01s7b5y08","country_code":"US","type":"education","lineage":["https://openalex.org/I83809506"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lucrecia A. Hernandez","raw_affiliation_strings":["Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]},{"raw_affiliation_string":"Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014512255","display_name":"Matthew B. Grisham","orcid":"https://orcid.org/0000-0001-9090-721X","observed_orcids":["https://orcid.org/0000-0001-9090-721X"]},"institutions":[{"id":"https://openalex.org/I83809506","display_name":"University of South Alabama","ror":"https://ror.org/01s7b5y08","country_code":"US","type":"education","lineage":["https://openalex.org/I83809506"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew B. Grisham","raw_affiliation_strings":["Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]},{"raw_affiliation_string":"Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055112840","display_name":"D. Neil Granger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I83809506","display_name":"University of South Alabama","ror":"https://ror.org/01s7b5y08","country_code":"US","type":"education","lineage":["https://openalex.org/I83809506"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. Neil Granger","raw_affiliation_strings":["Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]},{"raw_affiliation_string":"Department of Physiology, University of South Alabama, MSB 3024, Mobile, Alabama, 36688, USA","institution_ids":["https://openalex.org/I83809506"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I83809506"],"apc_list":null,"apc_paid":null,"fwci":1.5538,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.75793651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"201","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9384999871253967,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.9384999871253967,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.014399999752640724,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.009499999694526196,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/copper","display_name":"copper","score":0.5619999766349792},{"id":"https://openalex.org/keywords/ischemia-reperfusion-injury","display_name":"ischemia-reperfusion injury","score":0.9269999861717224},{"id":"https://openalex.org/keywords/oxygen-free-radicals","display_name":"oxygen free radicals","score":0.9850000143051147},{"id":"https://openalex.org/keywords/free-radical-scavengers","display_name":"radical scavengers","score":0.9279999732971191},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.5220000147819519},{"id":"https://openalex.org/keywords/tissue-damage","display_name":"tissue damage","score":0.7059999704360962},{"id":"https://openalex.org/keywords/digestive-organs","display_name":"digestive organs","score":0.5109999775886536},{"id":"https://openalex.org/keywords/microvascular-injury","display_name":"microvascular damage","score":0.5419999957084656},{"id":"https://openalex.org/keywords/reperfusion","display_name":"reperfusion","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.8663066625595093},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.7151709198951721},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5457094311714172},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.5078476071357727},{"id":"https://openalex.org/C2780114680","wikidata":"https://www.wikidata.org/wiki/Q1413991","display_name":"Reperfusion injury","level":3,"score":0.48768889904022217},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4402177929878235},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.42529773712158203},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3859519958496094},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.352944552898407},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2827434241771698},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20448705554008484},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4612-4584-1_16","doi":"https://doi.org/10.1007/978-1-4612-4584-1_16","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4612-4584-1_16","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology of Copper Complexes","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.7300000190734863,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1506333726","https://openalex.org/W1507589487","https://openalex.org/W1522676079","https://openalex.org/W1583870157","https://openalex.org/W1655445995","https://openalex.org/W1975462120","https://openalex.org/W1983634320","https://openalex.org/W1990117710","https://openalex.org/W2024586647","https://openalex.org/W2024902129","https://openalex.org/W2037355109","https://openalex.org/W2040230470","https://openalex.org/W2040618794","https://openalex.org/W2056168344","https://openalex.org/W2061871863","https://openalex.org/W2069098102","https://openalex.org/W2075519163","https://openalex.org/W2080664472","https://openalex.org/W2158513847","https://openalex.org/W2214755720","https://openalex.org/W2413123126","https://openalex.org/W2464074621"],"related_works":["https://openalex.org/W1211777005","https://openalex.org/W1586039582","https://openalex.org/W2416342265","https://openalex.org/W4237759738","https://openalex.org/W2511713289","https://openalex.org/W2415074088","https://openalex.org/W2097744068","https://openalex.org/W2467253450","https://openalex.org/W3187919439","https://openalex.org/W173765027"],"abstract_inverted_index":{"A":[0],"number":[1],"of":[2,13,18,41,80,104,116],"mechanisms":[3],"have":[4],"been":[5],"invoked":[6],"to":[7,33,44,100],"explain":[8],"ischemia-induced":[9],"tissue":[10,91,110],"injury.":[11],"One":[12],"these":[14],"mechanisms,":[15],"the":[16,39,49,72,90,102,117,135,142,148],"production":[17],"oxygen-derived":[19,105],"free":[20,30,67,106],"radicals,":[21],"has":[22],"received":[23],"particular":[24],"attention":[25],"in":[26,38,108],"recent":[27],"years.":[28],"Oxygen-derived":[29],"radicals":[31,86,107],"appear":[32],"play":[34],"a":[35],"major":[36],"role":[37],"pathogenesis":[40],"ischemia-reperfusion":[42],"injury":[43,111],"digestive":[45],"organs,":[46],"such":[47],"as":[48,147],"intestine,":[50],"1,2,3,4":[51],"stomach,":[52],"5":[53],"liver":[54],"6":[55],"and":[56,74,122,132,141],"pancreas.":[57],"7":[58],"This":[59,137],"assertion":[60],"is":[61,139],"largely":[62],"based":[63],"on":[64],"observations":[65],"that":[66,95],"radical":[68],"scavengers":[69],"significantly":[70],"attenuate":[71],"microvascular":[73],"parenchymal":[75],"damage":[76,92],"associated":[77],"with":[78],"reperfusion":[79],"ischemic":[81,109],"tissues.":[82],"Also,":[83],"when":[84],"oxygen":[85],"are":[87],"generated":[88],"experimentally,":[89],"produced":[93],"mimics":[94],"observed":[96],"after":[97],"ischemia-reperfusion.8":[98],"Evidence":[99],"support":[101],"involvement":[103],"also":[112],"comes":[113],"from":[114],"studies":[115],"coronary,":[118],"9,10,11":[119],"renal":[120],"12,13":[121],"cutaneous":[123],"circulations.":[124],"14":[125],"These":[126],"keywords":[127,143],"were":[128],"added":[129],"by":[130,134],"machine":[131],"not":[133],"authors.":[136],"process":[138],"experimental":[140],"may":[144],"be":[145],"updated":[146],"learning":[149],"algorithm":[150],"improves.":[151]},"counts_by_year":[],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}