{"id":"https://openalex.org/W1553599434","doi":"https://doi.org/10.2142/biophys.50.s20_2","title":"1P008 Two Distinct Mechanisms for Actin Capping Protein Regulation- Steric and Allosteric Inhibition(Protein:Structure,The 48th Annual Meeting of the Biophysical Society of Japan)","display_name":"1P008 Two Distinct Mechanisms for Actin Capping Protein Regulation- Steric and Allosteric Inhibition(Protein:Structure,The 48th Annual Meeting of the Biophysical Society of Japan)","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1553599434","doi":"https://doi.org/10.2142/biophys.50.s20_2","mag":"1553599434"},"language":"en","primary_location":{"id":"doi:10.2142/biophys.50.s20_2","doi":"https://doi.org/10.2142/biophys.50.s20_2","is_oa":true,"landing_page_url":"https://doi.org/10.2142/biophys.50.s20_2","pdf_url":"https://www.jstage.jst.go.jp/article/biophys/50/supplement2/50_KJ00006866830/_pdf","source":{"id":"https://openalex.org/S71018124","display_name":"Seibutsu Butsuri","issn_l":"0582-4052","issn":["0582-4052","1347-4219"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313296","host_organization_name":"Physical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313296"],"host_organization_lineage_names":["Physical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seibutsu Butsuri","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jstage.jst.go.jp/article/biophys/50/supplement2/50_KJ00006866830/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Shuichi Takeda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210104871","display_name":"SPring-8","ror":"https://ror.org/01d1kv753","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I4210111000"]},{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shuichi Takeda","raw_affiliation_strings":["Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030680321","display_name":"Shiho Minakata","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210104871","display_name":"SPring-8","ror":"https://ror.org/01d1kv753","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I4210111000"]},{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shiho Minakata","raw_affiliation_strings":["ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I4210104871","https://openalex.org/I4210110652"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088515417","display_name":"Ryotaro Koike","orcid":"https://orcid.org/0000-0003-2965-6954","observed_orcids":["https://orcid.org/0000-0003-2965-6954"]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryotaro Koike","raw_affiliation_strings":["Graduate School of Information Science, Nagoya University:Institute for Bioinformatics Research and Development, JST"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science, Nagoya University:Institute for Bioinformatics Research and Development, JST","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103033541","display_name":"K. Kawahata","orcid":"https://orcid.org/0000-0002-5916-7847","observed_orcids":["https://orcid.org/0000-0002-5916-7847"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ichiro Kawahata","raw_affiliation_strings":["Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058058056","display_name":"Akihiro Narita","orcid":"https://orcid.org/0000-0003-1504-9352","observed_orcids":["https://orcid.org/0000-0003-1504-9352"]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210104871","display_name":"SPring-8","ror":"https://ror.org/01d1kv753","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I4210111000"]},{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Akihiro Narita","raw_affiliation_strings":["Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Division of Biological Science, Graduate School of Science, Nagoya University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Division of Biological Science, Graduate School of Science, Nagoya University","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Masashi Kitazawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masashi Kitazawa","raw_affiliation_strings":["Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004774267","display_name":"Motonori Ota","orcid":"https://orcid.org/0000-0001-9090-668X","observed_orcids":["https://orcid.org/0000-0001-9090-668X"]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Motonori Ota","raw_affiliation_strings":["Graduate School of Information Science, Nagoya University:Institute for Bioinformatics Research and Development, JST"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Information Science, Nagoya University:Institute for Bioinformatics Research and Development, JST","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090014059","display_name":"Tohru Yamakuni","orcid":"https://orcid.org/0000-0003-3968-7949","observed_orcids":["https://orcid.org/0000-0003-3968-7949"]},"institutions":[{"id":"https://openalex.org/I201537933","display_name":"Tohoku University","ror":"https://ror.org/01dq60k83","country_code":"JP","type":"education","lineage":["https://openalex.org/I201537933"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tohru Yamakuni","raw_affiliation_strings":["Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacotherapy, Graduate School of Pharmaceutical Sciences, Tohoku University","institution_ids":["https://openalex.org/I201537933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057984567","display_name":"Yuichiro Ma\u00e9da","orcid":"https://orcid.org/0000-0002-5173-9409","observed_orcids":["https://orcid.org/0000-0002-5173-9409"]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210104871","display_name":"SPring-8","ror":"https://ror.org/01d1kv753","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I4210111000"]},{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuichiro Maeda","raw_affiliation_strings":["Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Division of Biological Science, Graduate School of Science, Nagoya University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structural Biology Research Center, Nagoya University:ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Division of Biological Science, Graduate School of Science, Nagoya University","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I60134161"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051657820","display_name":"Yasushi Nitanai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086780","display_name":"Japan Science and Technology Agency","ror":"https://ror.org/00097mb19","country_code":"JP","type":"government","lineage":["https://openalex.org/I1319490839","https://openalex.org/I4210086780"]},{"id":"https://openalex.org/I4210104871","display_name":"SPring-8","ror":"https://ror.org/01d1kv753","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210104871","https://openalex.org/I4210110652","https://openalex.org/I4210111000"]},{"id":"https://openalex.org/I4210110652","display_name":"RIKEN","ror":"https://ror.org/01sjwvz98","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210110652"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasushi Nitanai","raw_affiliation_strings":["ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Structural Biophysics Laboratory, RIKEN SPring-8 Center, Hyogo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ERATO Actin Filament Dynamics Project, JST, co RIKEN SPring-8 Center:Structural Biophysics Laboratory, RIKEN SPring-8 Center, Hyogo","institution_ids":["https://openalex.org/I4210086780","https://openalex.org/I4210104871","https://openalex.org/I4210110652"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"50","issue":"supplement2","first_page":"S20","last_page":"S20"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.6151999831199646,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.3594000041484833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/actin-capping-protein","display_name":"actin capping protein","score":0.9760000109672546},{"id":"https://openalex.org/keywords/actin-filament-capping","display_name":"actin filament capping","score":0.5649999976158142},{"id":"https://openalex.org/keywords/steric-inhibition","display_name":"steric inhibition","score":0.921999990940094},{"id":"https://openalex.org/keywords/allosteric-inhibition","display_name":"allosteric inhibition","score":0.9739999771118164},{"id":"https://openalex.org/keywords/protein-regulation","display_name":"protein regulation","score":0.6150000095367432},{"id":"https://openalex.org/keywords/actin-filament-dynamics","display_name":"actin filament dynamics","score":0.4059999883174896}],"concepts":[{"id":"https://openalex.org/C166342909","wikidata":"https://www.wikidata.org/wiki/Q845326","display_name":"Allosteric regulation","level":3,"score":0.8307847380638123},{"id":"https://openalex.org/C201194858","wikidata":"https://www.wikidata.org/wiki/Q898238","display_name":"Steric effects","level":2,"score":0.7003855109214783},{"id":"https://openalex.org/C125705527","wikidata":"https://www.wikidata.org/wiki/Q185269","display_name":"Actin","level":2,"score":0.5218490362167358},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4922553598880768},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4516269266605377},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4262154698371887},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.23346665501594543},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20981496572494507},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.12384748458862305},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.03970813751220703}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2142/biophys.50.s20_2","doi":"https://doi.org/10.2142/biophys.50.s20_2","is_oa":true,"landing_page_url":"https://doi.org/10.2142/biophys.50.s20_2","pdf_url":"https://www.jstage.jst.go.jp/article/biophys/50/supplement2/50_KJ00006866830/_pdf","source":{"id":"https://openalex.org/S71018124","display_name":"Seibutsu Butsuri","issn_l":"0582-4052","issn":["0582-4052","1347-4219"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313296","host_organization_name":"Physical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313296"],"host_organization_lineage_names":["Physical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seibutsu Butsuri","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2142/biophys.50.s20_2","doi":"https://doi.org/10.2142/biophys.50.s20_2","is_oa":true,"landing_page_url":"https://doi.org/10.2142/biophys.50.s20_2","pdf_url":"https://www.jstage.jst.go.jp/article/biophys/50/supplement2/50_KJ00006866830/_pdf","source":{"id":"https://openalex.org/S71018124","display_name":"Seibutsu Butsuri","issn_l":"0582-4052","issn":["0582-4052","1347-4219"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310313296","host_organization_name":"Physical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313296"],"host_organization_lineage_names":["Physical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Seibutsu Butsuri","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1553599434.pdf","grobid_xml":"https://content.openalex.org/works/W1553599434.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2031948792","https://openalex.org/W2086768845","https://openalex.org/W566160728","https://openalex.org/W3004850405","https://openalex.org/W2415550081","https://openalex.org/W7222981676","https://openalex.org/W2610214996","https://openalex.org/W420037447","https://openalex.org/W2021636759","https://openalex.org/W4388209128"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}