{"id":"https://openalex.org/W1553589968","doi":"https://doi.org/10.4049/jimmunol.168.3.1198","title":"Overexpression of IL-15 In Vivo Increases Antigen-Driven Memory CD8+ T Cells Following a Microbe Exposure","display_name":"Overexpression of IL-15 In Vivo Increases Antigen-Driven Memory CD8+ T Cells Following a Microbe Exposure","publication_year":2002,"publication_date":"2002-02-01","ids":{"openalex":"https://openalex.org/W1553589968","doi":"https://doi.org/10.4049/jimmunol.168.3.1198","mag":"1553589968","pmid":"https://pubmed.ncbi.nlm.nih.gov/11801655"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.168.3.1198","doi":"https://doi.org/10.4049/jimmunol.168.3.1198","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.168.3.1198","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/168/3/1198/1146091/1198.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.aai.org/jimmunol/article-pdf/168/3/1198/1146091/1198.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062363424","display_name":"Toshiki Yajima","orcid":"https://orcid.org/0000-0003-0574-9558","observed_orcids":["https://orcid.org/0000-0003-0574-9558"]},"institutions":[{"id":"https://openalex.org/I165735259","display_name":"Gunma University","ror":"https://ror.org/046fm7598","country_code":"JP","type":"education","lineage":["https://openalex.org/I165735259"]},{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Toshiki Yajima","raw_affiliation_strings":["First Department of Surgery, Gunma University School of Medicine , Maebashi ,","Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","\u2020First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Surgery, Gunma University School of Medicine , Maebashi ,","institution_ids":["https://openalex.org/I165735259"]},{"raw_affiliation_string":"Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"\u2020First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan;","institution_ids":["https://openalex.org/I165735259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026854132","display_name":"Hitoshi Nishimura","orcid":"https://orcid.org/0000-0001-5068-1738","observed_orcids":["https://orcid.org/0000-0001-5068-1738"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hitoshi Nishimura","raw_affiliation_strings":["Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031732894","display_name":"Ryotaro Ishimitsu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Ryotaro Ishimitsu","raw_affiliation_strings":["Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049983912","display_name":"Taketo Watase","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taketo Watase","raw_affiliation_strings":["Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","institution_ids":["https://openalex.org/I60134161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062895290","display_name":"Dirk Hans Busch","orcid":"https://orcid.org/0000-0001-8713-093X","observed_orcids":["https://orcid.org/0000-0001-8713-093X","https://orcid.org/0000-0002-0685-4483"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dirk H Busch","raw_affiliation_strings":["Sections of Infectious Diseases and Immunology, Yale University School of Medicine , New Haven, CT 06520"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sections of Infectious Diseases and Immunology, Yale University School of Medicine , New Haven, CT 06520","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025998259","display_name":"Eric G. Pamer","orcid":"https://orcid.org/0000-0002-6755-9904","observed_orcids":["https://orcid.org/0000-0002-6755-9904"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric G Pamer","raw_affiliation_strings":["\u00a7Infectious Disease Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Immunology Program, Sloan-Kettering Institue, New York, NY 10021"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7Infectious Disease Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Immunology Program, Sloan-Kettering Institue, New York, NY 10021","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017461232","display_name":"Hiroyuki Kuwano","orcid":"https://orcid.org/0000-0003-1809-8483","observed_orcids":["https://orcid.org/0000-0003-1809-8483"]},"institutions":[{"id":"https://openalex.org/I165735259","display_name":"Gunma University","ror":"https://ror.org/046fm7598","country_code":"JP","type":"education","lineage":["https://openalex.org/I165735259"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyuki Kuwano","raw_affiliation_strings":["First Department of Surgery, Gunma University School of Medicine , Maebashi ,","\u2020First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"First Department of Surgery, Gunma University School of Medicine , Maebashi ,","institution_ids":["https://openalex.org/I165735259"]},{"raw_affiliation_string":"\u2020First Department of Surgery, Gunma University School of Medicine, Maebashi, Japan;","institution_ids":["https://openalex.org/I165735259"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079931764","display_name":"Yasunobu Yoshikai","orcid":"https://orcid.org/0000-0002-8629-6628","observed_orcids":["https://orcid.org/0000-0002-8629-6628"]},"institutions":[{"id":"https://openalex.org/I60134161","display_name":"Nagoya University","ror":"https://ror.org/04chrp450","country_code":"JP","type":"education","lineage":["https://openalex.org/I60134161"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasunobu Yoshikai","raw_affiliation_strings":["Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine , Nagoya ,","institution_ids":["https://openalex.org/I60134161"]},{"raw_affiliation_string":"*Laboratory of Host Defense, Research Institute for Disease Mechanism and Control, Nagoya University School of Medicine, Nagoya, Japan;","institution_ids":["https://openalex.org/I60134161"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":6.5725,"has_fulltext":true,"cited_by_count":118,"citation_normalized_percentile":{"value":0.97371156,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"168","issue":"3","first_page":"1198","last_page":"1203"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/il-15","display_name":"IL-15","score":0.9440000057220459},{"id":"https://openalex.org/keywords/memory-cd8-t-cells","display_name":"memory CD8+ T cells","score":0.9810000061988831},{"id":"https://openalex.org/keywords/listeria-monocytogenes-infection","display_name":"Listeria monocytogenes infection","score":0.8690000176429749},{"id":"https://openalex.org/keywords/antigen-specific-t-cells","display_name":"antigen-specific T cells","score":0.7509999871253967},{"id":"https://openalex.org/keywords/listeriolysin-o","display_name":"listeriolysin O","score":0.8510000109672546},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.8529999852180481},{"id":"https://openalex.org/keywords/bcl-2","display_name":"Bcl-2","score":0.8199999928474426},{"id":"https://openalex.org/keywords/homeostatic-proliferation","display_name":"homeostatic proliferation","score":0.8870000243186951},{"id":"https://openalex.org/keywords/t-cell-survival","display_name":"T cell survival","score":0.8230000138282776},{"id":"https://openalex.org/keywords/adoptive-transfer","display_name":"adoptive transfer","score":0.7400000095367432},{"id":"https://openalex.org/keywords/infection-resistance","display_name":"infection resistance","score":0.5130000114440918}],"concepts":[{"id":"https://openalex.org/C2781275251","wikidata":"https://www.wikidata.org/wiki/Q17146593","display_name":"Listeriolysin O","level":5,"score":0.7642642259597778},{"id":"https://openalex.org/C154317977","wikidata":"https://www.wikidata.org/wiki/Q376266","display_name":"Cytotoxic T cell","level":3,"score":0.6410573124885559},{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.6356514692306519},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5759693384170532},{"id":"https://openalex.org/C90375314","wikidata":"https://www.wikidata.org/wiki/Q3537484","display_name":"Adoptive cell transfer","level":4,"score":0.5321542024612427},{"id":"https://openalex.org/C2781350384","wikidata":"https://www.wikidata.org/wiki/Q292015","display_name":"Listeria monocytogenes","level":3,"score":0.5029246211051941},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.48675990104675293},{"id":"https://openalex.org/C129374314","wikidata":"https://www.wikidata.org/wiki/Q909381","display_name":"Interleukin 21","level":4,"score":0.4516335427761078},{"id":"https://openalex.org/C170627219","wikidata":"https://www.wikidata.org/wiki/Q13218497","display_name":"MHC class I","level":4,"score":0.42948171496391296},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.42299920320510864},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.419941782951355},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3761870861053467},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.37496501207351685},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.35126757621765137},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.33100759983062744},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.20998325943946838},{"id":"https://openalex.org/C2778682378","wikidata":"https://www.wikidata.org/wiki/Q746209","display_name":"Listeria","level":4,"score":0.16552314162254333},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07421758770942688},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.05267602205276489},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001427","descriptor_name":"Bacterial Toxins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D006360","descriptor_name":"Heat-Shock Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006460","descriptor_name":"Hemolysin Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007156","descriptor_name":"Immunologic Memory","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007274","descriptor_name":"Injections, Intraperitoneal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008088","descriptor_name":"Listeriosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008088","descriptor_name":"Listeriosis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008088","descriptor_name":"Listeriosis","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015395","descriptor_name":"Histocompatibility Antigens Class I","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016176","descriptor_name":"T-Lymphocyte Subsets","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false},{"descriptor_ui":"D018984","descriptor_name":"Epitopes, T-Lymphocyte","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D019264","descriptor_name":"Adoptive Transfer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019409","descriptor_name":"Interleukin-15","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D019409","descriptor_name":"Interleukin-15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019409","descriptor_name":"Interleukin-15","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.4049/jimmunol.168.3.1198","doi":"https://doi.org/10.4049/jimmunol.168.3.1198","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.168.3.1198","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/168/3/1198/1146091/1198.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:11801655","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11801655","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunology (Baltimore, Md. : 1950)","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.328.8568","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.8568","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.jimmunol.org/content/168/3/1198.full.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.4049/jimmunol.168.3.1198","doi":"https://doi.org/10.4049/jimmunol.168.3.1198","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.168.3.1198","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/168/3/1198/1146091/1198.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4399999976158142}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1553589968.pdf","grobid_xml":"https://content.openalex.org/works/W1553589968.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W984887640","https://openalex.org/W1487210663","https://openalex.org/W1491154613","https://openalex.org/W1537543309","https://openalex.org/W1567604499","https://openalex.org/W1603412780","https://openalex.org/W1671586832","https://openalex.org/W1721293578","https://openalex.org/W1898780846","https://openalex.org/W1915573248","https://openalex.org/W1971302107","https://openalex.org/W1981480494","https://openalex.org/W1997196319","https://openalex.org/W2006027051","https://openalex.org/W2006073656","https://openalex.org/W2006981670","https://openalex.org/W2008366157","https://openalex.org/W2015778512","https://openalex.org/W2016914965","https://openalex.org/W2017072222","https://openalex.org/W2017728303","https://openalex.org/W2018597572","https://openalex.org/W2025465431","https://openalex.org/W2028091596","https://openalex.org/W2028583067","https://openalex.org/W2042578023","https://openalex.org/W2045183298","https://openalex.org/W2049271050","https://openalex.org/W2058035453","https://openalex.org/W2067069532","https://openalex.org/W2069340283","https://openalex.org/W2079303984","https://openalex.org/W2081097093","https://openalex.org/W2094384995","https://openalex.org/W2095433065","https://openalex.org/W2095739043","https://openalex.org/W2106539308","https://openalex.org/W2117342688","https://openalex.org/W2122268178","https://openalex.org/W2125010485","https://openalex.org/W2130098661","https://openalex.org/W2133567701","https://openalex.org/W2139056292","https://openalex.org/W2142285575","https://openalex.org/W2142621481","https://openalex.org/W2145933283","https://openalex.org/W2150751062","https://openalex.org/W2159531745","https://openalex.org/W2160430737","https://openalex.org/W2288397384"],"related_works":["https://openalex.org/W2058035453","https://openalex.org/W2114263643","https://openalex.org/W1544769291","https://openalex.org/W808919061","https://openalex.org/W2149104293","https://openalex.org/W1505467055","https://openalex.org/W2500380786","https://openalex.org/W1505315838","https://openalex.org/W1921456558","https://openalex.org/W1584891848"],"abstract_inverted_index":{"To":[0],"elucidate":[1],"potential":[2],"roles":[3],"of":[4,9,18,46,82,98,120,151,162],"IL-15":[5,36,87,113,132,143],"in":[6,35,64,74,103,130,136,148],"the":[7,16,117],"maintenance":[8,150],"memory":[10,48,153],"CD8+":[11,20,49,69,83,108,124,154],"T":[12,21,50,70,84,109,125,155],"cells,":[13],"we":[14],"followed":[15],"fate":[17],"Ag-specific":[19,152],"cells":[22,51,71,85,110,126,156],"directly":[23],"visualized":[24],"with":[25,31,91],"MHC":[26],"class":[27],"I":[28],"tetramers":[29],"coupled":[30],"listeriolysin":[32],"O":[33],"(LLO)(91-99)":[34],"transgenic":[37],"(Tg)":[38],"mice":[39,89,115,134],"after":[40,60],"Listeria":[41],"monocytogenes":[42,93,102],"infection.":[43],"The":[44,67,106],"numbers":[45],"LLO(91-99)-positive":[47,68],"were":[52],"significantly":[53],"higher":[54,96,118],"at":[55],"3":[56],"and":[57,78,165],"6":[58],"wk":[59],"infection":[61],"than":[62,135],"those":[63],"non-Tg":[65,137],"mice.":[66,105,138],"produced":[72],"IFN-gamma":[73],"response":[75],"to":[76],"LLO(91-99),":[77],"an":[79,145],"adoptive":[80],"transfer":[81],"from":[86,111],"Tg":[88,114,133],"infected":[90,112],"L.":[92,101],"conferred":[94],"a":[95],"level":[97,119],"resistance":[99],"against":[100],"normal":[104],"CD44+":[107,123],"expressed":[116],"Bcl-2.":[121],"Transferred":[122],"divided":[127],"more":[128],"vigorously":[129],"naive":[131],"These":[139],"results":[140],"suggest":[141],"that":[142],"plays":[144],"important":[146],"role":[147],"long-term":[149],"following":[157],"microbial":[158],"exposure":[159],"via":[160],"promotion":[161],"cell":[163],"survival":[164],"homeostatic":[166],"proliferation.":[167]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}