{"id":"https://openalex.org/W1551903609","doi":"https://doi.org/10.1002/jgm.1608","title":"Effect of vascular endothelial growth factor gene transfer on infarct size, left ventricular function and myocardial perfusion in sheep after 2 months of coronary artery occlusion","display_name":"Effect of vascular endothelial growth factor gene transfer on infarct size, left ventricular function and myocardial perfusion in sheep after 2 months of coronary artery occlusion","publication_year":2011,"publication_date":"2011-09-28","ids":{"openalex":"https://openalex.org/W1551903609","doi":"https://doi.org/10.1002/jgm.1608","mag":"1551903609","pmid":"https://pubmed.ncbi.nlm.nih.gov/21954009"},"language":"en","primary_location":{"id":"doi:10.1002/jgm.1608","doi":"https://doi.org/10.1002/jgm.1608","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jgm.1608","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgm.1608","source":{"id":"https://openalex.org/S91057606","display_name":"The Journal of Gene Medicine","issn_l":"1099-498X","issn":["1099-498X","1521-2254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Gene Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgm.1608","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042455109","display_name":"Gustavo Vera Janavel","orcid":"https://orcid.org/0000-0003-4626-6990","observed_orcids":["https://orcid.org/0000-0003-4626-6990"]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Gustavo L. Vera Janavel","raw_affiliation_strings":["Bio Sidus, Buenos Aires, Argentina","Department of Physiology, Favaloro University, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio Sidus, Buenos Aires, Argentina","institution_ids":[]},{"raw_affiliation_string":"Department of Physiology, Favaloro University, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrea De Lorenzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]},{"id":"https://openalex.org/I4210122565","display_name":"Fundacion Favaloro Hospital Universitario","ror":"https://ror.org/02x5wzm46","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210122565","https://openalex.org/I4210154782"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Andrea De Lorenzi","raw_affiliation_strings":["Favaloro University Hospital, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Favaloro University Hospital, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979","https://openalex.org/I4210122565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030736495","display_name":"Claudia Mariana Cort\u00e9s","orcid":"https://orcid.org/0000-0002-4799-1660","observed_orcids":["https://orcid.org/0000-0002-4799-1660"]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]},{"id":"https://openalex.org/I4210122565","display_name":"Fundacion Favaloro Hospital Universitario","ror":"https://ror.org/02x5wzm46","country_code":"AR","type":"healthcare","lineage":["https://openalex.org/I4210122565","https://openalex.org/I4210154782"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Claudia Cort\u00e9s","raw_affiliation_strings":["Favaloro University Hospital, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Favaloro University Hospital, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979","https://openalex.org/I4210122565"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052357212","display_name":"Fernanda Daniela Olea","orcid":"https://orcid.org/0000-0002-6938-0430","observed_orcids":["https://orcid.org/0000-0002-6938-0430"]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Fernanda D. Olea","raw_affiliation_strings":["Department of Physiology, Favaloro University, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Favaloro University, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050798138","display_name":"Patricia M. Cabeza Meckert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Patricia Cabeza Meckert","raw_affiliation_strings":["Department of Pathology, Favaloro University, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Favaloro University, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013278853","display_name":"Andr\u00e9s Bercovich","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andr\u00e9s Bercovich","raw_affiliation_strings":["Bio Sidus, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio Sidus, Buenos Aires, Argentina","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037103254","display_name":"Marcelo E. Criscuolo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcelo Criscuolo","raw_affiliation_strings":["Bio Sidus, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bio Sidus, Buenos Aires, Argentina","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111746283","display_name":"Ruben Pedro Laguens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Rub\u00e9n Laguens","raw_affiliation_strings":["Department of Pathology, Favaloro University, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Favaloro University, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033044208","display_name":"Alberto Crottogini","orcid":"https://orcid.org/0000-0002-5234-0539","observed_orcids":["https://orcid.org/0000-0002-5234-0539"]},"institutions":[{"id":"https://openalex.org/I187398979","display_name":"Favaloro University","ror":"https://ror.org/05s004555","country_code":"AR","type":"education","lineage":["https://openalex.org/I187398979"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Alberto Crottogini","raw_affiliation_strings":["Department of Physiology, Favaloro University, Buenos Aires, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology, Favaloro University, Buenos Aires, Argentina","institution_ids":["https://openalex.org/I187398979"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033044208"],"corresponding_institution_ids":["https://openalex.org/I187398979"],"apc_list":{"value":4480,"currency":"USD","value_usd":4480},"apc_paid":null,"fwci":1.9322,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.86648778,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"4","first_page":"279","last_page":"287"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.19679999351501465,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.19679999351501465,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.18039999902248383,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.13570000231266022,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9890000224113464},{"id":"https://openalex.org/keywords/gene-transfer","display_name":"gene transfer","score":0.7919999957084656},{"id":"https://openalex.org/keywords/plasmid-dna","display_name":"plasmid DNA","score":0.7160000205039978},{"id":"https://openalex.org/keywords/acute-myocardial-infarction","display_name":"acute myocardial infarction","score":0.8989999890327454},{"id":"https://openalex.org/keywords/coronary-artery-occlusion","display_name":"coronary artery occlusion","score":0.9290000200271606},{"id":"https://openalex.org/keywords/infarct-size","display_name":"infarct size","score":0.9179999828338623},{"id":"https://openalex.org/keywords/left-ventricular-function","display_name":"left ventricular function","score":0.9750000238418579},{"id":"https://openalex.org/keywords/myocardial-perfusion","display_name":"myocardial perfusion","score":0.9940000176429749},{"id":"https://openalex.org/keywords/cardiomyocyte-proliferation","display_name":"cardiomyocyte proliferation","score":0.7310000061988831},{"id":"https://openalex.org/keywords/cardiac-remodeling","display_name":"cardiac remodeling","score":0.6309999823570251},{"id":"https://openalex.org/keywords/sheep-model","display_name":"sheep model","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.7876729369163513},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7529305219650269},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7133514881134033},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.665379524230957},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.6067394614219666},{"id":"https://openalex.org/C2777408375","wikidata":"https://www.wikidata.org/wiki/Q707810","display_name":"Arteriogenesis","level":3,"score":0.4783762991428375},{"id":"https://openalex.org/C2776157398","wikidata":"https://www.wikidata.org/wiki/Q497232","display_name":"Coronary circulation","level":3,"score":0.45721718668937683},{"id":"https://openalex.org/C2777798775","wikidata":"https://www.wikidata.org/wiki/Q207550","display_name":"Infarction","level":3,"score":0.4437673091888428},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.41736704111099243},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.41234713792800903},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.23916223645210266},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.22524532675743103}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D042461","descriptor_name":"Vascular Endothelial Growth Factor A","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D054059","descriptor_name":"Coronary Occlusion","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D054059","descriptor_name":"Coronary Occlusion","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D054059","descriptor_name":"Coronary Occlusion","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1002/jgm.1608","doi":"https://doi.org/10.1002/jgm.1608","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jgm.1608","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgm.1608","source":{"id":"https://openalex.org/S91057606","display_name":"The Journal of Gene Medicine","issn_l":"1099-498X","issn":["1099-498X","1521-2254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Gene Medicine","raw_type":"journal-article"},{"id":"pmid:21954009","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21954009","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of gene medicine","raw_type":"Journal Article"},{"id":"pmh:oai:ri.conicet.gov.ar:11336/192882","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11336/192882","pdf_url":null,"source":{"id":"https://openalex.org/S4306401400","display_name":"Conicet","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210104196","host_organization_name":"Centro Cient\u00edfico Tecnol\u00f3gico - Nordeste","host_organization_lineage":["https://openalex.org/I4210104196"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1002/jgm.1608","doi":"https://doi.org/10.1002/jgm.1608","is_oa":true,"landing_page_url":"https://doi.org/10.1002/jgm.1608","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jgm.1608","source":{"id":"https://openalex.org/S91057606","display_name":"The Journal of Gene Medicine","issn_l":"1099-498X","issn":["1099-498X","1521-2254"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Gene Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G282104698","display_name":null,"funder_award_id":"BID 1728 OC/AR","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"},{"id":"https://openalex.org/G7378882120","display_name":null,"funder_award_id":"CONICET","funder_id":"https://openalex.org/F4320334832","funder_display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica"}],"funders":[{"id":"https://openalex.org/F4320321594","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59"},{"id":"https://openalex.org/F4320334832","display_name":"Agencia Nacional de Promoci\u00f3n Cient\u00edfica y Tecnol\u00f3gica","ror":"https://ror.org/03stxzb56"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1551903609.pdf","grobid_xml":"https://content.openalex.org/works/W1551903609.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1973226626","https://openalex.org/W1989456266","https://openalex.org/W2008016893","https://openalex.org/W2014855350","https://openalex.org/W2015165887","https://openalex.org/W2019549114","https://openalex.org/W2028036560","https://openalex.org/W2036442606","https://openalex.org/W2036876430","https://openalex.org/W2044110796","https://openalex.org/W2046225222","https://openalex.org/W2047697564","https://openalex.org/W2054120564","https://openalex.org/W2075177785","https://openalex.org/W2076048601","https://openalex.org/W2085860140","https://openalex.org/W2089449686","https://openalex.org/W2090770744","https://openalex.org/W2091325859","https://openalex.org/W2113900255","https://openalex.org/W2119194880","https://openalex.org/W2123027854","https://openalex.org/W2127480545","https://openalex.org/W2152843042","https://openalex.org/W2154252560","https://openalex.org/W2174842019","https://openalex.org/W2252543283","https://openalex.org/W2297695240","https://openalex.org/W2990123797"],"related_works":["https://openalex.org/W2015165887","https://openalex.org/W7127999547","https://openalex.org/W1986368300","https://openalex.org/W1980778777","https://openalex.org/W2015618974","https://openalex.org/W4247664580","https://openalex.org/W2756687245","https://openalex.org/W2075177785","https://openalex.org/W2025057216","https://openalex.org/W2352349897"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,211],"large":[2],"mammalian":[3],"models":[4],"of":[5,25,90,93,147,207,240],"acute":[6],"myocardial":[7,168],"infarction":[8],"(AMI),":[9],"plasmid-mediated":[10],"vascular":[11],"endothelial":[12],"growth":[13],"factor":[14],"(pVEGF)":[15],"gene":[16,216],"transfer":[17,217],"has":[18],"been":[19],"shown":[20],"to":[21,84],"induce":[22],"angio-arteriogenesis,":[23],"proliferation":[24,206],"myocyte":[26],"precursors":[27],"and":[28,69,104,114,126,156,170,194,205,227,230],"adult":[29],"cardiomyocyte":[30,208],"mitosis,":[31],"reducing":[32,231],"infarct":[33,63,101,161,220],"size":[34,125,133,221],"at":[35,50,99,159],"15":[36],"days":[37,106],"after":[38,164],"coronary":[39,79],"artery":[40,80],"occlusion.":[41],"However,":[42],"it":[43],"is":[44],"unknown":[45],"whether":[46],"these":[47],"effects":[48,200],"persist":[49],"longer":[51],"follow-up":[52],"times,":[53],"nor":[54],"how":[55],"they":[56],"affect":[57],"cardiac":[58],"performance.":[59],"We":[60],"thus":[61],"assessed":[62],"size,":[64],"left":[65],"ventricular":[66],"(LV)":[67],"function":[68,115,179,226],"perfusion":[70,109,169,228],"in":[71,137,191,196,243],"2-month-old":[72],"ovine":[73],"AMI.":[74],"METHODS:":[75],"Adult":[76],"sheep":[77,139,212],"with":[78,203,213],"occlusion":[81],"were":[82,118,129,201],"randomized":[83],"blindly":[85],"receive":[86],"ten":[87],"intramyocardial":[88],"injections":[89],"3.8":[91],"mg":[92],"pVEGF":[94,192,215],"or":[95],"empty":[96],"plasmid":[97],"distributed":[98],"the":[100,148,160,186,237,244],"border.":[102],"Three":[103],"60":[105],"later,":[107],"LV":[108,171,178,225],"(single-photon":[110],"emission":[111],"computed":[112],"tomography)":[113],"(stress":[116],"echocardiography)":[117],"assessed.":[119],"Finally,":[120],"hemodynamics":[121],"(LV":[122],"catheterization),":[123],"scar":[124],"peri-infarct":[127],"histology":[128],"studied.":[130],"RESULTS:":[131],"Infarct":[132],"was":[134,189],"30%":[135],"smaller":[136],"pVEGF-treated":[138],"(23.6":[140],"\u00b1":[141,145],"1.9%":[142],"versus":[143],"32.7":[144],"2.7%":[146],"LV;":[149],"p":[150],"<":[151],"0.02).":[152],"Percentage":[153],"fractional":[154],"shortening":[155],"wall":[157,172],"thickening":[158],"border":[162],"improved":[163],"pVEGF,":[165],"as":[166],"did":[167,180],"motion":[173],"under":[174],"pharmacological":[175],"stress.":[176],"Global":[177],"not":[181],"differ":[182],"between":[183],"groups,":[184],"although":[185],"force-frequency":[187],"response":[188],"preserved":[190],"group":[193],"lost":[195],"placebo":[197],"animals.":[198],"These":[199,234],"associated":[202],"angio-arteriogenesis":[204],"precursors.":[209],"CONCLUSIONS:":[210],"AMI,":[214],"affords":[218],"long-term":[219],"reduction,":[222],"yielding":[223],"regional":[224],"improvement":[229],"remodeling":[232],"progression.":[233],"results":[235],"suggest":[236],"potential":[238],"usefulness":[239],"this":[241],"approach":[242],"clinical":[245],"setting.":[246]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}