{"id":"https://openalex.org/W1549065172","doi":null,"title":"Lack of association of miR-146a and Ets-1 gene polymorphisms with Fuchs uveitis syndrome in Chinese Han patients.","display_name":"Lack of association of miR-146a and Ets-1 gene polymorphisms with Fuchs uveitis syndrome in Chinese Han patients.","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1549065172","mag":"1549065172","pmid":"https://pubmed.ncbi.nlm.nih.gov/22355253","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3283209"},"language":"en","primary_location":{"id":"pmid:22355253","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22355253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular vision","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3283209/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101595947","display_name":"Qingyun Zhou","orcid":"https://orcid.org/0000-0002-5176-0769","observed_orcids":["https://orcid.org/0000-0002-5176-0769"]},"institutions":[{"id":"https://openalex.org/I4210129459","display_name":"The Affiliated Yongchuan Hospital of Chongqing Medical University","ror":"https://ror.org/033vnzz93","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210129459"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingyun Zhou","raw_affiliation_strings":["The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, and Chongqing Eye Institute, Chongqing, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Ophthalmology, and Chongqing Eye Institute, Chongqing, P.R. China","institution_ids":["https://openalex.org/I4210129459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005016013","display_name":"Aize Kijlstra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aize Kijlstra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036936453","display_name":"Shengping Hou","orcid":"https://orcid.org/0000-0002-7796-8891","observed_orcids":["https://orcid.org/0000-0002-7796-8891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shengping Hou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059340675","display_name":"Hongsong Yu","orcid":"https://orcid.org/0000-0002-1209-2104","observed_orcids":["https://orcid.org/0000-0002-1209-2104"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongsong Yu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008342306","display_name":"Xuedong Zhang","orcid":"https://orcid.org/0000-0002-1347-3136","observed_orcids":["https://orcid.org/0000-0002-1347-3136"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xuedong Zhang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100406111","display_name":"Xinyu Li","orcid":"https://orcid.org/0000-0002-5908-6676","observed_orcids":["https://orcid.org/0000-0002-5908-6676","https://orcid.org/0009-0007-2183-8127","https://orcid.org/0009-0005-8507-2891"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xinyu Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101864876","display_name":"Xiang Xiao","orcid":"https://orcid.org/0000-0001-6644-6118","observed_orcids":["https://orcid.org/0000-0001-6644-6118"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiang Xiao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5000508996","display_name":"Peizeng Yang","orcid":"https://orcid.org/0000-0002-2647-6619","observed_orcids":["https://orcid.org/0000-0002-2647-6619"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peizeng Yang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.4115,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.79446866,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"18","issue":null,"first_page":"426","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12989","display_name":"Ocular Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fuchs-uveitis-syndrome","display_name":"Fuchs uveitis syndrome","score":0.9819999933242798},{"id":"https://openalex.org/keywords/mir-146a","display_name":"miR-146a","score":0.9739999771118164},{"id":"https://openalex.org/keywords/ets1","display_name":"ETS1","score":0.968999981880188},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.921999990940094},{"id":"https://openalex.org/keywords/genetic-association","display_name":"genetic association","score":0.7670000195503235},{"id":"https://openalex.org/keywords/han-chinese","display_name":"Han Chinese","score":0.6330000162124634},{"id":"https://openalex.org/keywords/rs2910164","display_name":"rs2910164","score":0.8930000066757202},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.37599998712539673}],"concepts":[{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.7718574404716492},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.696084201335907},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6802711486816406},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.577104389667511},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.54647296667099},{"id":"https://openalex.org/C168007829","wikidata":"https://www.wikidata.org/wiki/Q857299","display_name":"Restriction fragment length polymorphism","level":4,"score":0.4810202717781067},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4757382869720459},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.4555342197418213},{"id":"https://openalex.org/C175239580","wikidata":"https://www.wikidata.org/wiki/Q656595","display_name":"Genotype frequency","level":5,"score":0.4152378439903259},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.41434773802757263}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013577","descriptor_name":"Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014606","descriptor_name":"Uveitis, Anterior","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D050784","descriptor_name":"Proto-Oncogene Protein c-ets-1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D056726","descriptor_name":"Genetic Association Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"pmid:22355253","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22355253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular vision","raw_type":"Journal Article"},{"id":"pmh:oai:cris.maastrichtuniversity.nl:openaire_cris_publications/325ac56c-3aad-432a-90a0-176313eda029","doi":null,"is_oa":false,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/325ac56c-3aad-432a-90a0-176313eda029","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhou, Q, Kijlstra, A, Hou, S, Yu, H, Zhang, X, Li, X, Xiao, X & Yang, P 2012, 'Lack of association of miR-146a and Ets-1 gene polymorphisms with Fuchs uveitis syndrome in Chinese Han patients', Molecular Vision, vol. 18, no. 45-47, pp. 426-430.","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pubmedcentral.nih.gov:3283209","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3283209/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Vis","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.271.3904","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.271.3904","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/d8/1c/Mol_Vis_2012_Feb_11_18_426-430.tar.gz","raw_type":"text"},{"id":"pmh:um:oai:cris.maastrichtuniversity.nl:publications/325ac56c-3aad-432a-90a0-176313eda029","doi":null,"is_oa":false,"landing_page_url":"https://cris.maastrichtuniversity.nl/en/publications/325ac56c-3aad-432a-90a0-176313eda029","pdf_url":null,"source":{"id":"https://openalex.org/S4306402616","display_name":"Research Publications (Maastricht University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34352273","host_organization_name":"Maastricht University","host_organization_lineage":["https://openalex.org/I34352273"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecular Vision, 18(45-47), 426 - 430. Molecular Vision","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:1549065172","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22355253","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3283209","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC3283209/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Vis","raw_type":"Text"},"sustainable_development_goals":[{"score":0.9789000153541565,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321550","display_name":"Chongqing Science and Technology Commission","ror":"https://ror.org/05w9erc61"},{"id":"https://openalex.org/F4320327726","display_name":"Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W51691464","https://openalex.org/W144423133","https://openalex.org/W174750716","https://openalex.org/W252127166","https://openalex.org/W1829371653","https://openalex.org/W1964509888","https://openalex.org/W1965893507","https://openalex.org/W1975437957","https://openalex.org/W1978046970","https://openalex.org/W1983962406","https://openalex.org/W1987466751","https://openalex.org/W1994744171","https://openalex.org/W2029461740","https://openalex.org/W2033241914","https://openalex.org/W2034627425","https://openalex.org/W2037994182","https://openalex.org/W2054516100","https://openalex.org/W2055894297","https://openalex.org/W2056603566","https://openalex.org/W2073839280","https://openalex.org/W2074199582","https://openalex.org/W2075860675","https://openalex.org/W2096388504","https://openalex.org/W2128124507","https://openalex.org/W2133124222","https://openalex.org/W2133613657","https://openalex.org/W2134406094","https://openalex.org/W2136059996","https://openalex.org/W2139181526","https://openalex.org/W2151025094","https://openalex.org/W2155898804"],"related_works":["https://openalex.org/W7100982052","https://openalex.org/W2016924387","https://openalex.org/W7095334663","https://openalex.org/W2249150029","https://openalex.org/W2037994182","https://openalex.org/W2149783678","https://openalex.org/W2032278472","https://openalex.org/W4281563703","https://openalex.org/W3193278842","https://openalex.org/W1973687831"],"abstract_inverted_index":{"PURPOSE:":[0],"The":[1],"aim":[2],"of":[3,12,78,104,109],"this":[4],"study":[5],"was":[6],"to":[7,97],"investigate":[8],"the":[9,51,65,73,92,107,120,134],"potential":[10],"association":[11,108],"microRNA-146a":[13],"(miR-146a)":[14],"and":[15,35,46,75,81,91,111,126],"V-Ets":[16],"oncogene":[17],"homolog":[18],"1":[19],"(Ets-1)":[20],"gene":[21],"polymorphisms":[22,31,83],"with":[23,44,89,113,131],"Fuchs":[24],"Uveitis":[25],"syndrome":[26],"(FUS).":[27],"METHODS:":[28],"Three":[29],"single-nucleotide":[30],"(SNPs),":[32],"miR-146a/rs2910164,":[33,124],"ets-1/rs1128334,":[34,125],"ets-1/rs10893872":[36],"were":[37,62],"genotyped":[38],"in":[39,133],"219":[40],"Han":[41,135],"Chinese":[42,136],"patients":[43,88],"FUS":[45,90,132],"612":[47],"healthy":[48],"controls":[49],"using":[50],"polymerase":[52],"chain":[53],"reaction-restriction":[54],"fragment":[55],"length":[56],"polymorphism":[57],"(PCR-RFLP)":[58],"method.":[59],"Genotype":[60],"counts":[61],"analyzed":[63],"by":[64],"\u03c7\u00b2":[66],"test.":[67],"RESULTS:":[68],"No":[69],"significant":[70],"difference":[71],"concerning":[72],"genotypic":[74],"allelic":[76],"frequencies":[77],"rs2910164,":[79],"rs1128334,":[80],"rs10893872":[82],"could":[84],"be":[85],"found":[86],"between":[87],"normal":[93],"controls.":[94],"Analysis":[95],"according":[96],"gender":[98],"did":[99],"not":[100,129],"show":[101],"any":[102],"influence":[103],"sex":[105],"on":[106],"miR-146a":[110],"Ets-1":[112],"FUS.":[114],"CONCLUSIONS:":[115],"Our":[116],"results":[117],"suggest":[118],"that":[119],"investigated":[121],"three":[122],"SNPs,":[123],"ets-1/rs10893872,":[127],"are":[128],"associated":[130],"population.":[137]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}