{"id":"https://openalex.org/W1546541543","doi":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","title":"Genotypic analysis of genes associated with isoniazid and ethionamide resistance in MDR-TB isolates from Thailand","display_name":"Genotypic analysis of genes associated with isoniazid and ethionamide resistance in MDR-TB isolates from Thailand","publication_year":2009,"publication_date":"2009-05-27","ids":{"openalex":"https://openalex.org/W1546541543","doi":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","mag":"1546541543","pmid":"https://pubmed.ncbi.nlm.nih.gov/19486070"},"language":"en","primary_location":{"id":"doi:10.1111/j.1469-0691.2009.02838.x","doi":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","pdf_url":null,"source":{"id":"https://openalex.org/S71414007","display_name":"Clinical Microbiology and Infection","issn_l":"1198-743X","issn":["1198-743X","1469-0691"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology and Infection","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032167278","display_name":"S. Boonaiam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"S. Boonaiam","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine Siriraj Hospital, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","Department of Microbiology, Faculty of Medicine Siriraj Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine Siriraj Hospital, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158"]},{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine Siriraj Hospital","institution_ids":["https://openalex.org/I1332387789"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047287766","display_name":"Angkana Chaiprasert","orcid":"https://orcid.org/0000-0002-6333-947X","observed_orcids":["https://orcid.org/0000-0002-6333-947X"]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I4405270826","display_name":"Siriraj Foundation","ror":"https://ror.org/01chvxb17","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I4405270826"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"A. Chaiprasert","raw_affiliation_strings":["Department of Microbiology, Faculty of Medicine Siriraj Hospital","Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology, Faculty of Medicine Siriraj Hospital","institution_ids":["https://openalex.org/I1332387789"]},{"raw_affiliation_string":"Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158","https://openalex.org/I4405270826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051006509","display_name":"Therdsak Prammananan","orcid":"https://orcid.org/0000-0002-5132-1440","observed_orcids":["https://orcid.org/0000-0002-5132-1440"]},"institutions":[{"id":"https://openalex.org/I1332092204","display_name":"National Science and Technology Development Agency","ror":"https://ror.org/04vy95b61","country_code":"TH","type":"government","lineage":["https://openalex.org/I1332092204"]},{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I4405270826","display_name":"Siriraj Foundation","ror":"https://ror.org/01chvxb17","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I4405270826"]},{"id":"https://openalex.org/I902798049","display_name":"National Center for Genetic Engineering and Biotechnology","ror":"https://ror.org/047aswc67","country_code":"TH","type":"facility","lineage":["https://openalex.org/I1332092204","https://openalex.org/I902798049"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"T. Prammananan","raw_affiliation_strings":["Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University","National Centre for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathumthaniand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158","https://openalex.org/I4405270826"]},{"raw_affiliation_string":"National Centre for Genetic Engineering and Biotechnology, National Science and Technology Development Agency, Pathumthaniand","institution_ids":["https://openalex.org/I1332092204","https://openalex.org/I902798049"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020776095","display_name":"Manoon Leechawengwongs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]},{"id":"https://openalex.org/I25399158","display_name":"Mahidol University","ror":"https://ror.org/01znkr924","country_code":"TH","type":"education","lineage":["https://openalex.org/I25399158"]},{"id":"https://openalex.org/I4405270826","display_name":"Siriraj Foundation","ror":"https://ror.org/01chvxb17","country_code":"TH","type":"nonprofit","lineage":["https://openalex.org/I4405270826"]},{"id":"https://openalex.org/I4405277443","display_name":"Vichaiyut Hospital","ror":"https://ror.org/02q0n2952","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4405277443"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"M. Leechawengwongs","raw_affiliation_strings":["Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University","Vichaiyut Hospital, Bangkok, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug-Resistant Tuberculosis Research Fund, Siriraj Foundation, Faculty of Medicine Siriraj Hospital, Mahidol University","institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158","https://openalex.org/I4405270826"]},{"raw_affiliation_string":"Vichaiyut Hospital, Bangkok, Thailand","institution_ids":["https://openalex.org/I4405277443"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5047287766"],"corresponding_institution_ids":["https://openalex.org/I1332387789","https://openalex.org/I25399158","https://openalex.org/I4405270826"],"apc_list":{"value":3780,"currency":"USD","value_usd":3780},"apc_paid":null,"fwci":1.6367,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.81960038,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"16","issue":"4","first_page":"396","last_page":"399"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10147","display_name":"Antibiotic Resistance in Bacteria","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multidrug-resistant-tuberculosis","display_name":"multidrug-resistant tuberculosis","score":0.9539999961853027},{"id":"https://openalex.org/keywords/isoniazid-resistance","display_name":"isoniazid resistance","score":0.9559999704360962},{"id":"https://openalex.org/keywords/ethionamide-resistance","display_name":"ethionamide resistance","score":1.0},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.8690000176429749},{"id":"https://openalex.org/keywords/katg-mutations","display_name":"katG mutations","score":0.9319999814033508},{"id":"https://openalex.org/keywords/inha-promoter-mutations","display_name":"inhA promoter mutations","score":0.8730000257492065},{"id":"https://openalex.org/keywords/drug-resistance-genes","display_name":"drug resistance genes","score":0.7770000100135803},{"id":"https://openalex.org/keywords/thailand","display_name":"Thailand","score":0.8169999718666077}],"concepts":[{"id":"https://openalex.org/C2776448121","wikidata":"https://www.wikidata.org/wiki/Q414767","display_name":"Ethionamide","level":5,"score":0.9350343346595764},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.7049860954284668},{"id":"https://openalex.org/C2776967927","wikidata":"https://www.wikidata.org/wiki/Q423169","display_name":"Isoniazid","level":3,"score":0.6288838386535645},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5069068074226379},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4910886287689209},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.4646894931793213},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.4457653760910034},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4270741939544678},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.41910016536712646},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3724726438522339},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.36260390281677246},{"id":"https://openalex.org/C2776228421","wikidata":"https://www.wikidata.org/wiki/Q412318","display_name":"Ethambutol","level":4,"score":0.09268277883529663},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000995","descriptor_name":"Antitubercular Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002374","descriptor_name":"Catalase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005000","descriptor_name":"Ethionamide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007538","descriptor_name":"Isoniazid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009169","descriptor_name":"Mycobacterium tuberculosis","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D013785","descriptor_name":"Thailand","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017421","descriptor_name":"Sequence Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D018088","descriptor_name":"Tuberculosis, Multidrug-Resistant","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D024901","descriptor_name":"Drug Resistance, Multiple, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1469-0691.2009.02838.x","doi":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","pdf_url":null,"source":{"id":"https://openalex.org/S71414007","display_name":"Clinical Microbiology and Infection","issn_l":"1198-743X","issn":["1198-743X","1469-0691"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology and Infection","raw_type":"journal-article"},{"id":"pmid:19486070","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19486070","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1469-0691.2009.02838.x","doi":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1469-0691.2009.02838.x","pdf_url":null,"source":{"id":"https://openalex.org/S71414007","display_name":"Clinical Microbiology and Infection","issn_l":"1198-743X","issn":["1198-743X","1469-0691"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Microbiology and Infection","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321370","display_name":"Inha University","ror":"https://ror.org/01easw929"},{"id":"https://openalex.org/F4320322437","display_name":"National Science and Technology Development Agency","ror":"https://ror.org/04vy95b61"},{"id":"https://openalex.org/F4320335223","display_name":"Thailand Graduate Institute of Science and Technology","ror":"https://ror.org/02edr8z79"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1981198757","https://openalex.org/W2011605425","https://openalex.org/W2061061092","https://openalex.org/W2081719764","https://openalex.org/W2107384735","https://openalex.org/W2113280970","https://openalex.org/W2119603196","https://openalex.org/W2125427123","https://openalex.org/W2126996122","https://openalex.org/W2129852031","https://openalex.org/W2137144551","https://openalex.org/W2140586560","https://openalex.org/W2142392294","https://openalex.org/W2150843895","https://openalex.org/W2151256688","https://openalex.org/W2156997824","https://openalex.org/W2164087631","https://openalex.org/W2417116685","https://openalex.org/W2469780971","https://openalex.org/W2980659148"],"related_works":["https://openalex.org/W2467662207","https://openalex.org/W2151256688","https://openalex.org/W2131028539","https://openalex.org/W2469780971","https://openalex.org/W2125018815","https://openalex.org/W3185052669","https://openalex.org/W2354497952","https://openalex.org/W2347497205","https://openalex.org/W7096411458","https://openalex.org/W4377012402"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}