{"id":"https://openalex.org/W1546400949","doi":null,"title":"Parameters for defining efficacy in fracture healing.","display_name":"Parameters for defining efficacy in fracture healing.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1546400949","mag":"1546400949","pmid":"https://pubmed.ncbi.nlm.nih.gov/22461284","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2897999"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2897999","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2897999","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Cases Miner Bone Metab","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2897999","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064633070","display_name":"Tam\u00e1s Shisha","orcid":"https://orcid.org/0000-0003-3865-5435","observed_orcids":["https://orcid.org/0000-0003-3865-5435"]},"institutions":[{"id":"https://openalex.org/I4405268767","display_name":"Institut de Recherches Internationales Servier (France)","ror":"https://ror.org/01zej3n42","country_code":"FR","type":"company","lineage":["https://openalex.org/I4405268767"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Tamas Shisha","raw_affiliation_strings":["International Project Manager Therapeutic Division of Rheumatology Institut de Recherches Internationales Servier (I.R.I.S.)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"International Project Manager Therapeutic Division of Rheumatology Institut de Recherches Internationales Servier (I.R.I.S.)","institution_ids":["https://openalex.org/I4405268767"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5064633070"],"corresponding_institution_ids":["https://openalex.org/I4405268767"],"apc_list":null,"apc_paid":null,"fwci":0.3456,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.66726319,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"7","issue":"1","first_page":"15","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.7929999828338623,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10658","display_name":"Bone fractures and treatments","score":0.7929999828338623,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.13050000369548798,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11509","display_name":"Hip and Femur Fractures","score":0.06350000202655792,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fracture-healing","display_name":"fracture healing","score":0.9980000257492065},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.7379999756813049},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.7289999723434448},{"id":"https://openalex.org/keywords/elderly-patients","display_name":"elderly patients","score":0.9399999976158142}],"concepts":[{"id":"https://openalex.org/C8337478","wikidata":"https://www.wikidata.org/wiki/Q1777289","display_name":"Bone healing","level":2,"score":0.8180347084999084},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6897698640823364},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.6359535455703735},{"id":"https://openalex.org/C2994343686","wikidata":"https://www.wikidata.org/wiki/Q1753467","display_name":"Osteoporotic fracture","level":4,"score":0.5322976112365723},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.45698076486587524},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.42347782850265503},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.3758435845375061},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.33313149213790894},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.3325307369232178},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11151757836341858},{"id":"https://openalex.org/C2776886416","wikidata":"https://www.wikidata.org/wiki/Q4941567","display_name":"Bone mineral","level":3,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2897999","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2897999","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Cases Miner Bone Metab","raw_type":"Text"},{"id":"pmid:22461284","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22461284","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases","raw_type":"Journal Article"},{"id":"pmh:oai:eprints.bice.rm.cnr.it:5573","doi":null,"is_oa":true,"landing_page_url":"http://eprints.bice.rm.cnr.it/5573/1/portiere.php.pdf","pdf_url":"http://eprints.bice.rm.cnr.it/5573/1/portiere.php.pdf","source":{"id":"https://openalex.org/S4306402016","display_name":"CNR Solar (Scientific Open-access Literature Archive and Repository) (Consiglio Nazionale delle Ricerche)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210155236","host_organization_name":"National Research Council","host_organization_lineage":["https://openalex.org/I4210155236"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"mag:1546400949","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22461284","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:2187258430","doi":null,"is_oa":false,"landing_page_url":"http://eprints.bice.rm.cnr.it/5573/1/portiere.php.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2897999","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2897999","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Cases Miner Bone Metab","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9789999723434448}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1546400949.pdf","grobid_xml":"https://content.openalex.org/works/W1546400949.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1966994557","https://openalex.org/W2004189107","https://openalex.org/W2004960578","https://openalex.org/W2051249552","https://openalex.org/W2073473970","https://openalex.org/W2080321526","https://openalex.org/W2084909021","https://openalex.org/W2094654701","https://openalex.org/W2103905415","https://openalex.org/W2129331493","https://openalex.org/W2142078244"],"related_works":["https://openalex.org/W2187258430","https://openalex.org/W2103905415","https://openalex.org/W1488906040","https://openalex.org/W1580314244","https://openalex.org/W2022499027","https://openalex.org/W2137579492","https://openalex.org/W1969850988","https://openalex.org/W1988779086","https://openalex.org/W2946414404","https://openalex.org/W2464974282"],"abstract_inverted_index":{"Complications":[0],"of":[1,12,33,54,64],"the":[2,19,31,44,52,62],"bone-healing":[3],"process,":[4],"especially":[5],"in":[6,61],"elderly,":[7],"osteoporotic":[8],"patients,":[9],"are":[10],"cause":[11],"important":[13],"medical":[14],"and":[15],"economical":[16],"burden.":[17],"At":[18],"same":[20],"time,":[21],"there":[22],"is":[23],"no":[24],"clinical":[25,66],"study":[26],"today":[27],"to":[28,37,57],"have":[29],"shown":[30],"efficacy":[32,56],"a":[34,65],"pharmacological":[35],"treatment":[36,55],"enhance":[38,58],"fracture":[39,59],"repair.":[40],"The":[41],"author":[42],"analyzes":[43],"potential":[45],"criteria":[46],"that":[47],"could":[48],"be":[49],"used":[50],"for":[51],"evaluation":[53],"healing":[60],"frame":[63],"study.":[67]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}