{"id":"https://openalex.org/W1545504641","doi":null,"title":"Pro- and antioxidants and risk of atherosclerosis and coronary heart disease in the elderly","display_name":"Pro- and antioxidants and risk of atherosclerosis and coronary heart disease in the elderly","publication_year":1999,"publication_date":"1999-05-19","ids":{"openalex":"https://openalex.org/W1545504641","mag":"1545504641"},"language":"en","primary_location":{"id":"pmh:oai:repub.eur.nl:19834","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/19834","pdf_url":"http://repub.eur.nl/pub/19834","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://repub.eur.nl/pub/19834","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012933671","display_name":"Kerstin Klipstein\u2010Grobusch","orcid":"https://orcid.org/0000-0002-5462-9889","observed_orcids":["https://orcid.org/0000-0002-5462-9889"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kerstin Klipstein\u2010Grobusch","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5462-9889","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5012933671"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.711899995803833,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.22519999742507935,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.02669999934732914,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.6449999809265137},{"id":"https://openalex.org/keywords/pro-oxidants","display_name":"pro-oxidants","score":0.8960000276565552},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.9909999966621399},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":1.0},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9279999732971191},{"id":"https://openalex.org/keywords/modifiable-risk-factors","display_name":"modifiable risk factors","score":0.781000018119812},{"id":"https://openalex.org/keywords/diet","display_name":"diet","score":0.7250000238418579},{"id":"https://openalex.org/keywords/cardiovascular-disease-prevention","display_name":"cardiovascular disease prevention","score":0.7689999938011169},{"id":"https://openalex.org/keywords/cardiovascular-mortality","display_name":"cardiovascular mortality","score":0.5170000195503235}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7457844018936157},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.7139390110969543},{"id":"https://openalex.org/C2776962539","wikidata":"https://www.wikidata.org/wiki/Q6472078","display_name":"Lagging","level":2,"score":0.5919174551963806},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.5602209568023682},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.46880653500556946},{"id":"https://openalex.org/C29374701","wikidata":"https://www.wikidata.org/wiki/Q1931388","display_name":"Cause of death","level":3,"score":0.42490315437316895},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.35892254114151},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3315879702568054},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.32576853036880493},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.10515010356903076}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:repub.eur.nl:19834","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/19834","pdf_url":"http://repub.eur.nl/pub/19834","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:eur:oai:pure.eur.nl:publications/e8dfc23c-30bb-4eb3-9775-c482f8fffae9","doi":null,"is_oa":true,"landing_page_url":"https://pure.eur.nl/en/publications/e8dfc23c-30bb-4eb3-9775-c482f8fffae9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401266","display_name":"EUR Research Repository (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"pmh:eur:oai:repub.eur.nl:19834","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1765/19834","pdf_url":null,"source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralthesis"},{"id":"mag:1545504641","doi":null,"is_oa":false,"landing_page_url":"https://repub.eur.nl/pub/19834/990519_KLIPSTEIN-GROBUSCH, Kerstin.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repub.eur.nl:19834","doi":null,"is_oa":true,"landing_page_url":"http://repub.eur.nl/pub/19834","pdf_url":"http://repub.eur.nl/pub/19834","source":{"id":"https://openalex.org/S4377196287","display_name":"RePub (Erasmus University Rotterdam)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I913958620","host_organization_name":"Erasmus University Rotterdam","host_organization_lineage":["https://openalex.org/I913958620"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321009","display_name":"Erasmus Universiteit Rotterdam","ror":"https://ror.org/057w15z03"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1545504641.pdf","grobid_xml":"https://content.openalex.org/works/W1545504641.grobid-xml"},"referenced_works_count":149,"referenced_works":["https://openalex.org/W2178751","https://openalex.org/W38812705","https://openalex.org/W43976724","https://openalex.org/W145304105","https://openalex.org/W1203690880","https://openalex.org/W1525444530","https://openalex.org/W1526461192","https://openalex.org/W1538803231","https://openalex.org/W1554825621","https://openalex.org/W1596659916","https://openalex.org/W1767177186","https://openalex.org/W1823950544","https://openalex.org/W1826054418","https://openalex.org/W1836901909","https://openalex.org/W1857052429","https://openalex.org/W1894977589","https://openalex.org/W1900502813","https://openalex.org/W1912299173","https://openalex.org/W1919192868","https://openalex.org/W1923790355","https://openalex.org/W1926536076","https://openalex.org/W1927136117","https://openalex.org/W1937294600","https://openalex.org/W1953155253","https://openalex.org/W1965106723","https://openalex.org/W1968321080","https://openalex.org/W1970542553","https://openalex.org/W1972164300","https://openalex.org/W1974571932","https://openalex.org/W1987372995","https://openalex.org/W1991238911","https://openalex.org/W1998474412","https://openalex.org/W2002499171","https://openalex.org/W2002605005","https://openalex.org/W2006164530","https://openalex.org/W2008276715","https://openalex.org/W2008419967","https://openalex.org/W2010190957","https://openalex.org/W2013094638","https://openalex.org/W2014170882","https://openalex.org/W2016422333","https://openalex.org/W2017354690","https://openalex.org/W2017890625","https://openalex.org/W2018576224","https://openalex.org/W2021556840","https://openalex.org/W2023364246","https://openalex.org/W2023782645","https://openalex.org/W2028752982","https://openalex.org/W2029169456","https://openalex.org/W2033199106","https://openalex.org/W2040923416","https://openalex.org/W2041413195","https://openalex.org/W2042711729","https://openalex.org/W2043948984","https://openalex.org/W2046946523","https://openalex.org/W2047327988","https://openalex.org/W2047525244","https://openalex.org/W2047656324","https://openalex.org/W2048696850","https://openalex.org/W2050120865","https://openalex.org/W2051040693","https://openalex.org/W2051100738","https://openalex.org/W2051679847","https://openalex.org/W2054526264","https://openalex.org/W2056155902","https://openalex.org/W2056325568","https://openalex.org/W2059927203","https://openalex.org/W2064172838","https://openalex.org/W2064489577","https://openalex.org/W2065303599","https://openalex.org/W2069869836","https://openalex.org/W2070922892","https://openalex.org/W2074707768","https://openalex.org/W2077485235","https://openalex.org/W2077772009","https://openalex.org/W2085963018","https://openalex.org/W2088327041","https://openalex.org/W2090306478","https://openalex.org/W2092619576","https://openalex.org/W2092738144","https://openalex.org/W2095840354","https://openalex.org/W2097744068","https://openalex.org/W2098130011","https://openalex.org/W2099817703","https://openalex.org/W2101126663","https://openalex.org/W2103825558","https://openalex.org/W2104644780","https://openalex.org/W2107138005","https://openalex.org/W2107539572","https://openalex.org/W2109056425","https://openalex.org/W2110807383","https://openalex.org/W2110857771","https://openalex.org/W2111970004","https://openalex.org/W2112160364","https://openalex.org/W2114631174","https://openalex.org/W2116593667","https://openalex.org/W2120021843","https://openalex.org/W2121273469","https://openalex.org/W2121380625","https://openalex.org/W2124211672","https://openalex.org/W2125149999","https://openalex.org/W2125332656","https://openalex.org/W2127980872","https://openalex.org/W2129288396","https://openalex.org/W2132191286","https://openalex.org/W2135025966","https://openalex.org/W2135479614","https://openalex.org/W2136614806","https://openalex.org/W2138692437","https://openalex.org/W2139755134","https://openalex.org/W2141476680","https://openalex.org/W2146785268","https://openalex.org/W2147750381","https://openalex.org/W2149499805","https://openalex.org/W2153743722","https://openalex.org/W2154666720","https://openalex.org/W2155942116","https://openalex.org/W2156942108","https://openalex.org/W2159506419","https://openalex.org/W2160607602","https://openalex.org/W2160776746","https://openalex.org/W2161136053","https://openalex.org/W2162502194","https://openalex.org/W2163079946","https://openalex.org/W2163624012","https://openalex.org/W2165184785","https://openalex.org/W2168035727","https://openalex.org/W2184367691","https://openalex.org/W2188239345","https://openalex.org/W2188926221","https://openalex.org/W2225634735","https://openalex.org/W2259562363","https://openalex.org/W2265791998","https://openalex.org/W2266086759","https://openalex.org/W2271597477","https://openalex.org/W2283881916","https://openalex.org/W2302785252","https://openalex.org/W2313837936","https://openalex.org/W2315403385","https://openalex.org/W2317242858","https://openalex.org/W2318584852","https://openalex.org/W2329711941","https://openalex.org/W2334903440","https://openalex.org/W2336867199","https://openalex.org/W2398025931","https://openalex.org/W2415576490","https://openalex.org/W2430178731","https://openalex.org/W2463481513","https://openalex.org/W3126800207"],"related_works":["https://openalex.org/W4388911930","https://openalex.org/W2013430646","https://openalex.org/W2498731620","https://openalex.org/W2041773070","https://openalex.org/W131060946","https://openalex.org/W2526649021","https://openalex.org/W1973997817","https://openalex.org/W7099298729","https://openalex.org/W288156482","https://openalex.org/W4379512629"],"abstract_inverted_index":{"Coronary":[0,14],"heart":[1,15,155],"disease":[2,16,110],"(CHD)":[3],"is":[4,17,36,80,138],"an":[5],"increasing":[6],"global":[7],"problem":[8],"carrying":[9],"heavy":[10],"social\\nand":[11],"economic":[12],"costs.":[13],"responsible":[18],"for":[19,27,63],"about":[20],"50%":[21],"of\\ncardiovascular":[22],"mortality,":[23],"which":[24],"itselfs":[25],"accounts":[26],"30-50%":[28],"of":[29,40,86,93,118,127,151],"all":[30],"deaths":[31],"in":[32,43,46,56,67,81,112],"developed\\nnations":[33],"t.":[34],"It":[35],"the":[37,76,91,103,105,109,113,116,128],"major":[38],"cause":[39],"premature":[41],"death,":[42],"women":[44],"as":[45],"men":[47,51],"-":[48],"women\\nlagging":[49],"behind":[50],"by":[52,84],"some":[53],"ten":[54],"years":[55],"this":[57],"age-related":[58],"disease.":[59,136,156],"Knowledge":[60],"on":[61,125],"risk\\nfactors":[62],"CHD":[64,79],"has":[65],"accumulated":[66],"recent":[68],"years.":[69],"Research":[70],"evidence":[71],"now":[72],"lends":[73],"strong\\nsupport":[74],"to":[75,97,101,107,135],"view":[77],"that":[78],"part":[82],"preventable":[83],"reduction":[85],"modifiable":[87],"risk\\nfactors.":[88],"The":[89],"greater":[90,104],"number":[92],"risk":[94,121,129,141],"factors":[95,130,142],"known":[96],"be":[98],"causally":[99],"related":[100,134],"the\\ndisease,":[102],"power":[106],"reduce":[108],"burden":[111],"community":[114],"by\\nreducing":[115],"levels":[117],"such":[119],"pathogenic":[120],"factors,":[122],"though":[123],"depending":[124],"the\\nmodifiability":[126],"and":[131,143,147,153],"their":[132],"strength":[133],"Diet":[137],"among":[139],"the\\nmodifiable":[140],"provides":[144],"a":[145],"simple":[146],"non-pharmacologic":[148],"method":[149],"for\\nprevention":[150],"atherosclerosis":[152],"coronary":[154]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}