{"id":"https://openalex.org/W1543925548","doi":null,"title":"Signalling by inositides : a practical approach","display_name":"Signalling by inositides : a practical approach","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W1543925548","mag":"1543925548"},"language":"en","primary_location":{"id":"pmh:oai:aleph.bib-bvb.de:BVB01-028487930","doi":null,"is_oa":false,"landing_page_url":"http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=98505","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"software, multimedia"},"volume":null,"type":"other","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013107971","display_name":"Stephen B. Shears","orcid":"https://orcid.org/0000-0001-7309-8916","observed_orcids":["https://orcid.org/0000-0001-7309-8916"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Stephen B. Shears","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7309-8916","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5013107971"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13415","display_name":"Calcium signaling and nucleotide metabolism","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1314","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10952","display_name":"PI3K/AKT/mTOR signaling in cancer","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inositol-phosphate-turnover","display_name":"inositol phosphate turnover","score":0.859000027179718},{"id":"https://openalex.org/keywords/inositol-polyphosphates","display_name":"inositol polyphosphates","score":0.925000011920929},{"id":"https://openalex.org/keywords/phospholipase-c-gamma1","display_name":"phospholipase C-gamma1","score":0.8880000114440918},{"id":"https://openalex.org/keywords/phospholipase-c-delta","display_name":"phospholipase C delta","score":0.9509999752044678},{"id":"https://openalex.org/keywords/inositol-1-4-5-trisphosphate","display_name":"inositol 1,4,5-trisphosphate","score":0.9810000061988831},{"id":"https://openalex.org/keywords/phosphatidylinositol-4-5-bisphosphate","display_name":"phosphatidylinositol 4,5-bisphosphate","score":0.9950000047683716},{"id":"https://openalex.org/keywords/inositol-hexakisphosphate-kinase","display_name":"inositol hexakisphosphate kinase","score":0.9819999933242798},{"id":"https://openalex.org/keywords/phosphatidylinositol-3-kinase","display_name":"phosphatidylinositol 3-kinase","score":0.9929999709129333},{"id":"https://openalex.org/keywords/plant-cells","display_name":"plant cells","score":0.609000027179718},{"id":"https://openalex.org/keywords/g-protein-signaling","display_name":"G protein signaling","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C2777427919","wikidata":"https://www.wikidata.org/wiki/Q407997","display_name":"Inositol","level":3,"score":0.9478414058685303},{"id":"https://openalex.org/C2778597717","wikidata":"https://www.wikidata.org/wiki/Q420248","display_name":"Phospholipase C","level":3,"score":0.8256011605262756},{"id":"https://openalex.org/C2780610907","wikidata":"https://www.wikidata.org/wiki/Q2273248","display_name":"Phosphatidylinositol","level":3,"score":0.7572900652885437},{"id":"https://openalex.org/C2778618036","wikidata":"https://www.wikidata.org/wiki/Q2878809","display_name":"Inositol phosphate","level":4,"score":0.7091070413589478},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.64560467004776},{"id":"https://openalex.org/C66135807","wikidata":"https://www.wikidata.org/wiki/Q24726231","display_name":"Gq alpha subunit","level":4,"score":0.601916491985321},{"id":"https://openalex.org/C78297661","wikidata":"https://www.wikidata.org/wiki/Q10760862","display_name":"Phosphoinositide phospholipase C","level":4,"score":0.5467986464500427},{"id":"https://openalex.org/C2781387506","wikidata":"https://www.wikidata.org/wiki/Q138145","display_name":"Inositol trisphosphate","level":4,"score":0.5383580327033997},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5185742974281311},{"id":"https://openalex.org/C12927208","wikidata":"https://www.wikidata.org/wiki/Q210430","display_name":"Phospholipase","level":3,"score":0.4681921899318695},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44722995162010193},{"id":"https://openalex.org/C2778038992","wikidata":"https://www.wikidata.org/wiki/Q420783","display_name":"Polyphosphate","level":3,"score":0.411730021238327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40385109186172485},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.28877121210098267},{"id":"https://openalex.org/C2777132085","wikidata":"https://www.wikidata.org/wiki/Q46220103","display_name":"Phosphate","level":2,"score":0.2624931335449219},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.22216671705245972},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.13132068514823914}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:aleph.bib-bvb.de:BVB01-028487930","doi":null,"is_oa":false,"landing_page_url":"http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=98505","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"software, multimedia"},{"id":"mag:1543925548","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/ncid/BA3372729X","pdf_url":null,"source":{"id":"https://openalex.org/S4306473475","display_name":"IRL eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"ebook platform"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"IRL eBooks","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1559190352","https://openalex.org/W2021790094","https://openalex.org/W2911521597","https://openalex.org/W3216031285","https://openalex.org/W2106319575","https://openalex.org/W2033956194","https://openalex.org/W2057557532","https://openalex.org/W4388227837","https://openalex.org/W4388244345","https://openalex.org/W2056584404"],"abstract_inverted_index":{"1:":[0],"Assaying":[1],"inositol":[2,12,25,31,62,69,76,89],"phospholipid":[3],"turnover":[4,14],"in":[5,15],"plant":[6],"cells.":[7],"2:":[8],".":[9],"Measureent":[10],"of":[11,24,44,53,61,68,88],"phosphate":[13],"intact":[16],"cells":[17],"and":[18,26,41,51,59,71,86,92],"cell-free":[19],"systems.":[20],"3:":[21],"Mass":[22,66],"assay":[23,30,43,52,60,67,87],"its":[27],"use":[28],"to":[29],"polyphosphates.":[32],"4:":[33],"Phospholipase":[34],"C-gamma":[35],"1.":[36],"5:":[37],"Baculovirus-promoted":[38],"expression,":[39],"purification,":[40],"functional":[42],"G-protein":[45],"regulated":[46],"PLC-beta":[47],"isoenzymes.":[48],"6:":[49],"Purification":[50,85],"phospholipase":[54],"C-delta.":[55],"7:":[56],"The":[57,81],"purification":[58],"polyphosphate-binding":[63],"proteins.":[64],"8:":[65],"1,4,5-trisphosphate":[70],"phosphatidylinositol":[72],"4,5-bisphosphate.":[73],"9:":[74],"Desalting":[75],"polyphosphates":[77],"by":[78],"dialysis.":[79],"10:":[80],"Ins(1,4,5)P3":[82],"receptor.":[83],"11:":[84],"hexakisphosphate":[90],"kinase":[91],"diphosphoinositol":[93],"pentakisphosphate":[94],"kinase.":[95],"12:":[96],"Phosphoinositide":[97],"3-kinase":[98]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2016-06-24T00:00:00"}