{"id":"https://openalex.org/W1543601456","doi":"https://doi.org/10.1038/71090","title":"Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation","display_name":"Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W1543601456","doi":"https://doi.org/10.1038/71090","mag":"1543601456","pmid":"https://pubmed.ncbi.nlm.nih.gov/10607390"},"language":"en","primary_location":{"id":"doi:10.1038/71090","doi":"https://doi.org/10.1038/71090","is_oa":false,"landing_page_url":"https://doi.org/10.1038/71090","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046601204","display_name":"Yun\u2010Beom Choi","orcid":"https://orcid.org/0000-0001-9930-823X","observed_orcids":["https://orcid.org/0000-0001-9930-823X"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yun-Beom Choi","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, Boston, Massachusetts 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, Boston, Massachusetts 02115, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033969874","display_name":"Lalitha Tenneti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lalitha Tenneti","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109984700","display_name":"Dean A. Le","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dean A. Le","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Justin Ortiz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin Ortiz","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101857379","display_name":"Guang Bai","orcid":"https://orcid.org/0000-0003-4481-6135","observed_orcids":["https://orcid.org/0000-0003-4481-6135"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guang Bai","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038512318","display_name":"Huei-Sheng Vincent Chen","orcid":"https://orcid.org/0000-0002-5235-2505","observed_orcids":["https://orcid.org/0000-0002-5235-2505"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Huei-Sheng Vincent Chen","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066753734","display_name":"Stuart A. Lipton","orcid":"https://orcid.org/0000-0002-3490-1259","observed_orcids":["https://orcid.org/0000-0002-3490-1259"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I188891513","display_name":"Sanford Burnham Prebys Medical Discovery Institute","ror":"https://ror.org/03m1g2s55","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I188891513"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stuart A. Lipton","raw_affiliation_strings":["Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","Del E. Webb Center for Neuroscience and Aging Research, The Burnham Institute, La Jolla, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School, 221 Longwood Avenue, LMRC First Floor,  Boston, 02115, Massachusetts, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Cerebrovascular and Neuroscience Research Institute, Brigham and Women's Hospital, and Program in Neuroscience, Harvard Medical School,  Boston, USA","institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Del E. Webb Center for Neuroscience and Aging Research, The Burnham Institute, La Jolla, USA","institution_ids":["https://openalex.org/I188891513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5066753734"],"corresponding_institution_ids":["https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I188891513"],"apc_list":{"value":12690,"currency":"USD","value_usd":12690},"apc_paid":null,"fwci":6.5183,"has_fulltext":false,"cited_by_count":426,"citation_normalized_percentile":{"value":0.97761245,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"3","issue":"1","first_page":"15","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects","score":0.0284000001847744,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.013199999928474426,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":0.9860000014305115},{"id":"https://openalex.org/keywords/s-nitrosylation","display_name":"S-nitrosylation","score":0.9559999704360962},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9129999876022339},{"id":"https://openalex.org/keywords/ion-channel-modulation","display_name":"ion channel modulation","score":0.902999997138977},{"id":"https://openalex.org/keywords/nr2a-subunit","display_name":"NR2A subunit","score":0.9950000047683716}],"concepts":[{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.8510464429855347},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.7167280912399292},{"id":"https://openalex.org/C50254741","wikidata":"https://www.wikidata.org/wiki/Q62536","display_name":"Ion channel","level":3,"score":0.7015681266784668},{"id":"https://openalex.org/C2777553025","wikidata":"https://www.wikidata.org/wiki/Q25323683","display_name":"S-Nitrosylation","level":4,"score":0.6981188654899597},{"id":"https://openalex.org/C45068187","wikidata":"https://www.wikidata.org/wiki/Q9050270","display_name":"Nitrosylation","level":3,"score":0.6231070160865784},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6095273494720459},{"id":"https://openalex.org/C2779201268","wikidata":"https://www.wikidata.org/wiki/Q186474","display_name":"Cysteine","level":3,"score":0.5325305461883545},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5232937932014465},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.4506330192089081},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.4475277364253998},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.42285558581352234},{"id":"https://openalex.org/C167007842","wikidata":"https://www.wikidata.org/wiki/Q15322678","display_name":"TRPC1","level":4,"score":0.4210456609725952},{"id":"https://openalex.org/C16318435","wikidata":"https://www.wikidata.org/wiki/Q149299","display_name":"Mutagenesis","level":4,"score":0.4191140830516815},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4153003692626953},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.408061146736145},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.3293173909187317},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3254644274711609},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23474225401878357},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.06562712788581848},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003545","descriptor_name":"Cysteine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005020","descriptor_name":"Ethyl Methanesulfonate","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D005020","descriptor_name":"Ethyl Methanesulfonate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007202","descriptor_name":"Indicators and Reagents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D008698","descriptor_name":"Mesylates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009603","descriptor_name":"Nitroso Compounds","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010446","descriptor_name":"Peptide Fragments","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014162","descriptor_name":"Transfection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014982","descriptor_name":"Xenopus laevis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D016194","descriptor_name":"Receptors, N-Methyl-D-Aspartate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016202","descriptor_name":"N-Methylaspartate","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D016297","descriptor_name":"Mutagenesis, Site-Directed","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017136","descriptor_name":"Ion Transport","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017136","descriptor_name":"Ion Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018408","descriptor_name":"Patch-Clamp Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026403","descriptor_name":"S-Nitrosothiols","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/71090","doi":"https://doi.org/10.1038/71090","is_oa":false,"landing_page_url":"https://doi.org/10.1038/71090","pdf_url":null,"source":{"id":"https://openalex.org/S2298632","display_name":"Nature Neuroscience","issn_l":"1097-6256","issn":["1097-6256","1546-1726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","erih-plus","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Neuroscience","raw_type":"journal-article"},{"id":"pmid:10607390","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10607390","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature neuroscience","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G5720824472","display_name":"Cellular/Molecular Pathophysiology of Intellectual and Developmental Disabilities","funder_award_id":"P01HD029587","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G7040950592","display_name":"AIDS-Related Neurotoxicity and Novel NMDAR Antagonists","funder_award_id":"R01EY009024","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8217426186","display_name":"RETINAL GANGLION CELLS: ION CHANNELS & TRANSMITTERS","funder_award_id":"R01EY005477","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W111514246","https://openalex.org/W1532031053","https://openalex.org/W1606988289","https://openalex.org/W1772604871","https://openalex.org/W1849554878","https://openalex.org/W1908222510","https://openalex.org/W1970564284","https://openalex.org/W1971335269","https://openalex.org/W1975152691","https://openalex.org/W1977394169","https://openalex.org/W1979218462","https://openalex.org/W1986944932","https://openalex.org/W1987322407","https://openalex.org/W1988726352","https://openalex.org/W1994522080","https://openalex.org/W1994812970","https://openalex.org/W2005591501","https://openalex.org/W2008537587","https://openalex.org/W2009013636","https://openalex.org/W2009601307","https://openalex.org/W2010055809","https://openalex.org/W2010204734","https://openalex.org/W2013034385","https://openalex.org/W2013348596","https://openalex.org/W2016575029","https://openalex.org/W2022595505","https://openalex.org/W2023661816","https://openalex.org/W2023811880","https://openalex.org/W2024862570","https://openalex.org/W2025958644","https://openalex.org/W2035189018","https://openalex.org/W2042733026","https://openalex.org/W2052795247","https://openalex.org/W2053003352","https://openalex.org/W2053254546","https://openalex.org/W2053980736","https://openalex.org/W2062384458","https://openalex.org/W2063503589","https://openalex.org/W2064477978","https://openalex.org/W2085327871","https://openalex.org/W2087485118","https://openalex.org/W2090046344","https://openalex.org/W2092338483","https://openalex.org/W2094038408","https://openalex.org/W2099226007","https://openalex.org/W2103031848","https://openalex.org/W2126092103","https://openalex.org/W2129108032","https://openalex.org/W2143855170","https://openalex.org/W2238958281","https://openalex.org/W2316145923","https://openalex.org/W2468516752"],"related_works":["https://openalex.org/W2092338483","https://openalex.org/W2034361309","https://openalex.org/W111514246","https://openalex.org/W2079630381","https://openalex.org/W1567400085","https://openalex.org/W2086862625","https://openalex.org/W2018101787","https://openalex.org/W2133753097","https://openalex.org/W2010090151","https://openalex.org/W1986944932"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":11},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":18},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":14},{"year":2014,"cited_by_count":24},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":21}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}