{"id":"https://openalex.org/W1543470210","doi":null,"title":"Ca2+ Efflux from Temperature Sensitive Liposomes and In Situ Formation of Metal Cholate Liposome Gels: Basic Studies and Potentials for Sustained Site-Specific Drug Delivery","display_name":"Ca2+ Efflux from Temperature Sensitive Liposomes and In Situ Formation of Metal Cholate Liposome Gels: Basic Studies and Potentials for Sustained Site-Specific Drug Delivery","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W1543470210","mag":"1543470210"},"language":"en","primary_location":{"id":"mag:1543470210","doi":null,"is_oa":false,"landing_page_url":"https://www.iiste.org/Journals/index.php/CMR/article/download/9386/9608","pdf_url":null,"source":{"id":"https://openalex.org/S2764983057","display_name":"chemistry and materials research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"chemistry and materials research","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111445641","display_name":"Subhendu Das","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Subhendu Das","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Saroj K. Nayak","orcid":"https://orcid.org/0000-0001-6570-8964","observed_orcids":["https://orcid.org/0000-0001-6570-8964"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Saroj K. Nayak","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6570-8964","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5061757758","display_name":"Rajesh K. Singh","orcid":"https://orcid.org/0000-0002-5943-3498","observed_orcids":["https://orcid.org/0000-0002-5943-3498"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajesh K. Singh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5943-3498","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"3","issue":"13","first_page":"41","last_page":"48"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.3009999990463257,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.3009999990463257,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.2012999951839447,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.1776999980211258,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thermosensitive-liposomes","display_name":"thermosensitive liposomes","score":0.828000009059906},{"id":"https://openalex.org/keywords/calcium-efflux","display_name":"calcium efflux","score":0.7390000224113464},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.7039999961853027},{"id":"https://openalex.org/keywords/local-drug-delivery","display_name":"local drug delivery","score":0.8989999890327454},{"id":"https://openalex.org/keywords/antimicrobial-hydrogels","display_name":"antimicrobial hydrogels","score":0.8870000243186951},{"id":"https://openalex.org/keywords/calcium-sensitive-dyes","display_name":"calcium-sensitive dyes","score":0.4830000102519989},{"id":"https://openalex.org/keywords/arsenazo-iii","display_name":"arsenazo III","score":0.7910000085830688},{"id":"https://openalex.org/keywords/injectable-biomaterials","display_name":"injectable biomaterials","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C185154212","wikidata":"https://www.wikidata.org/wiki/Q410454","display_name":"Liposome","level":2,"score":0.9522448182106018},{"id":"https://openalex.org/C130316041","wikidata":"https://www.wikidata.org/wiki/Q189206","display_name":"Vesicle","level":3,"score":0.771054744720459},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6638049483299255},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6480679512023926},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.6420926451683044},{"id":"https://openalex.org/C192157962","wikidata":"https://www.wikidata.org/wiki/Q4087243","display_name":"Bilayer","level":3,"score":0.5592124462127686},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.488944411277771},{"id":"https://openalex.org/C2911023556","wikidata":"https://www.wikidata.org/wiki/Q287415","display_name":"Sodium Cholate","level":2,"score":0.4810657501220703},{"id":"https://openalex.org/C13245373","wikidata":"https://www.wikidata.org/wiki/Q3715494","display_name":"Drug carrier","level":3,"score":0.4510955512523651},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4446380138397217},{"id":"https://openalex.org/C39944091","wikidata":"https://www.wikidata.org/wiki/Q423279","display_name":"Lipid bilayer","level":3,"score":0.4257052540779114},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.41130900382995605},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.3666985034942627},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14967042207717896},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14259225130081177},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1543470210","doi":null,"is_oa":false,"landing_page_url":"https://www.iiste.org/Journals/index.php/CMR/article/download/9386/9608","pdf_url":null,"source":{"id":"https://openalex.org/S2764983057","display_name":"chemistry and materials research","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"chemistry and materials research","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.504800021648407,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1972154409","https://openalex.org/W1978029175","https://openalex.org/W1980970387","https://openalex.org/W2004313264","https://openalex.org/W2013726140","https://openalex.org/W2017716170","https://openalex.org/W2023103429","https://openalex.org/W2029950779","https://openalex.org/W2050197542","https://openalex.org/W2058460324","https://openalex.org/W2061510929","https://openalex.org/W2062133242","https://openalex.org/W2063034288","https://openalex.org/W2067353791","https://openalex.org/W2068642265","https://openalex.org/W2074368574","https://openalex.org/W2110892068","https://openalex.org/W2140124527","https://openalex.org/W2144957160","https://openalex.org/W2151878885","https://openalex.org/W2157220384","https://openalex.org/W2314397498","https://openalex.org/W2463227637","https://openalex.org/W2565567859"],"related_works":["https://openalex.org/W2065632458","https://openalex.org/W1997522053","https://openalex.org/W2070882593","https://openalex.org/W1994467229","https://openalex.org/W2985498750","https://openalex.org/W2036612589","https://openalex.org/W2140124527","https://openalex.org/W3035737243","https://openalex.org/W2009227902","https://openalex.org/W4399275433"],"abstract_inverted_index":{"Liposomes":[0],"or":[1],"vesicles":[2],"are":[3,28,32],"biomimetic":[4],"close":[5],"containers":[6],"for":[7,16,38,73,222,240,250,272],"the":[8,13,23,44,58,124,137,163,172,189,261],"delivery":[9,75],"of":[10,20,35,46,82,104,107,131,171,186,204,207,217,264],"drugs":[11],"at":[12,165],"local":[14,54],"site":[15],"an":[17],"extended":[18],"period":[19],"time.":[21],"On":[22],"other":[24],"hand":[25],"hydrogels":[26,190,265],"which":[27,68],"three-dimensional":[29],"hydrophilic":[30],"matrices":[31],"another":[33],"class":[34],"popular":[36],"materials":[37],"sustained":[39,53],"release.":[40],"Such":[41],"hybrids":[42],"combine":[43],"features":[45],"liposomes":[47,120,187],"and":[48,96,110,143,161],"polymer":[49],"to":[50,100,180],"ensure":[51],"a":[52,61,105,141],"drug":[55,74,252],"delivery.":[56,253,292],"In":[57],"present":[59,255],"work":[60,256],"novel":[62],"liposome/hydrogel":[63],"soft":[64],"assembly":[65],"is":[66,257],"explored":[67],"may":[69,236],"be":[70,238],"potentially":[71],"useful":[72,239],"applications.":[76],"We":[77,230],"report":[78],"thermally":[79],"triggered":[80,285],"release":[81],"Ca":[83,152,218],"+2":[84,153,219],"from":[86],"temperature":[87],"sensitive":[88,226],"liposomal\u00a0":[89],"compartments":[90],"constituted":[91],"as":[92,195,243,245,260],"90":[93],"mol%":[94,98],"DPPC":[95],"10":[97],"DMPC":[99],"induce":[101],"rapid":[102],"gelation":[103,175,194],"solution":[106],"calcium":[108,225],"cholate":[109,173,208,288],"AgNO":[111],"3":[112],"(extravesicular":[114],"precursor":[115,159],"fluid).":[116],"Calcium":[117],"chloride":[118],"loaded":[119,155],"were":[121,134,148,191],"prepared":[122],"using":[123,140],"lipid":[125],"film":[126],"rehydration":[127],"method.":[128],"The":[129,169,184,202,254],"formation":[130],"unilamellar":[132],"bilayer":[133],"supported":[135],"by":[136,150,197],"fluorometric":[138],"studies":[139],"compatible":[142],"labeled":[144],"fluoropore":[145],"(NBD-PS).":[146],"Hydrogels":[147],"obtained":[149],"mixing":[151],"liposome":[156,289],"with":[157],"extravesicular":[158],"fluid":[160],"incubating":[162],"content":[164],"37":[166],"o":[167],"C.":[168],"concentration":[170,206],"during":[174,193],"was":[176],"sublytic":[177],"in":[178],"order":[179],"avoid":[181],"vesicle":[182],"solubilization.":[183],"integrity":[185],"within":[188],"preserved":[192],"confirmed":[196],"transmission":[198],"electron":[199],"microscopy":[200],"(TEM).":[201],"presence":[203],"low":[205],"(for":[209],"example":[210],"0.05":[211],"mM)":[212],"also":[213,237,258],"permitted":[214],"spectrophotometric":[215],"monitoring":[216],"efflux":[221],"Ca-vesicles":[223],"employing":[224],"dye,":[227],"Arsenazo":[228],"III.\u00a0":[229],"expect":[231],"that":[232],"this":[233],"simple":[234],"experiment":[235],"developing":[241],"implantable":[242],"well":[244],"rapidly":[246],"gelling":[247],"injectable":[248],"biomaterials":[249],"site-specific":[251,291],"significant":[259],"antimicrobial":[262],"properties":[263],"containing":[266],"silver":[267],"has":[268],"been":[269],"widely":[270],"recognized":[271],"its":[273],"therapeutic":[274],"profile.\u00a0\u00a0":[275],"Keywords:":[282],"Liposome,":[284],"release,":[286],"metal":[287],"gel,":[290]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}