{"id":"https://openalex.org/W1542954872","doi":"https://doi.org/10.25011/cim.v34i6.15892","title":"Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction","display_name":"Relationship between mean platelet volume and left ventricular systolic function in patients with metabolic syndrome and ST-elevation myocardial infarction","publication_year":2011,"publication_date":"2011-12-01","ids":{"openalex":"https://openalex.org/W1542954872","doi":"https://doi.org/10.25011/cim.v34i6.15892","mag":"1542954872","pmid":"https://pubmed.ncbi.nlm.nih.gov/22129921"},"language":"en","primary_location":{"id":"doi:10.25011/cim.v34i6.15892","doi":"https://doi.org/10.25011/cim.v34i6.15892","is_oa":true,"landing_page_url":"https://doi.org/10.25011/cim.v34i6.15892","pdf_url":"https://cimonline.ca/index.php/cim/article/download/15892/12913","source":{"id":"https://openalex.org/S133894987","display_name":"Clinical and investigative medicine","issn_l":"0147-958X","issn":["0147-958X","1488-2353"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4324392715","host_organization_name":"The Canadian Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4324392715"],"host_organization_lineage_names":["The Canadian Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Investigative Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://cimonline.ca/index.php/cim/article/download/15892/12913","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111924144","display_name":"H\u00fcseyin U\u011fur Yaz\u0131c\u0131","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Huseyin U. Yazici","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004456396","display_name":"Fatih Poyraz","orcid":"https://orcid.org/0000-0001-9471-7261","observed_orcids":["https://orcid.org/0000-0001-9471-7261"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Fatih Poyraz","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069967896","display_name":"Nihat \u015een","orcid":"https://orcid.org/0000-0002-0478-7758","observed_orcids":["https://orcid.org/0000-0002-0478-7758"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Nihat Sen","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037512384","display_name":"Yusuf Tav\u0131l","orcid":"https://orcid.org/0000-0003-3487-6417","observed_orcids":["https://orcid.org/0000-0003-3487-6417"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yusuf Tavil","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005583469","display_name":"Murat Turfan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Murat Turfan","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047633700","display_name":"Murat Tulma\u00e7","orcid":"https://orcid.org/0000-0001-7491-5447","observed_orcids":["https://orcid.org/0000-0001-7491-5447"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Murat Tulma\u00e7","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051201326","display_name":"Adnan Abac\u0131","orcid":"https://orcid.org/0000-0001-8538-4733","observed_orcids":["https://orcid.org/0000-0001-8538-4733"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Adnan Abac\u0131","raw_affiliation_strings":["Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Gazi University, School of Medicine, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I95634034"],"apc_list":null,"apc_paid":null,"fwci":1.946,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.85623302,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"34","issue":"6","first_page":"E330","last_page":"E335"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.32280001044273376,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.32280001044273376,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.30959999561309814,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.25760000944137573,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mean-platelet-volume","display_name":"mean platelet volume","score":1.0},{"id":"https://openalex.org/keywords/left-ventricular-systolic-function","display_name":"left ventricular systolic function","score":0.953000009059906},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9909999966621399},{"id":"https://openalex.org/keywords/st-elevation-myocardial-infarction","display_name":"ST-elevation myocardial infarction","score":1.0},{"id":"https://openalex.org/keywords/platelet-activation","display_name":"platelet activation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/ejection-fraction","display_name":"ejection fraction","score":0.878000020980835},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8600000143051147},{"id":"https://openalex.org/keywords/systemic-inflammation","display_name":"systemic inflammation","score":0.4819999933242798},{"id":"https://openalex.org/keywords/thrombosis","display_name":"thrombosis","score":0.7400000095367432}],"concepts":[{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.8537182807922363},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8494554162025452},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8409873843193054},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.7503991723060608},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.750145435333252},{"id":"https://openalex.org/C78085059","wikidata":"https://www.wikidata.org/wiki/Q641303","display_name":"Ejection fraction","level":3,"score":0.6422063708305359},{"id":"https://openalex.org/C190481736","wikidata":"https://www.wikidata.org/wiki/Q6803639","display_name":"Mean platelet volume","level":3,"score":0.5196489095687866},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.48514851927757263},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.21956834197044373}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001792","descriptor_name":"Blood Platelets","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D010976","descriptor_name":"Platelet Count","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016015","descriptor_name":"Logistic Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016277","descriptor_name":"Ventricular Function, Left","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.25011/cim.v34i6.15892","doi":"https://doi.org/10.25011/cim.v34i6.15892","is_oa":true,"landing_page_url":"https://doi.org/10.25011/cim.v34i6.15892","pdf_url":"https://cimonline.ca/index.php/cim/article/download/15892/12913","source":{"id":"https://openalex.org/S133894987","display_name":"Clinical and investigative medicine","issn_l":"0147-958X","issn":["0147-958X","1488-2353"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4324392715","host_organization_name":"The Canadian Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4324392715"],"host_organization_lineage_names":["The Canadian Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Investigative Medicine","raw_type":"journal-article"},{"id":"pmid:22129921","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22129921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and investigative medicine. Medecine clinique et experimentale","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.25011/cim.v34i6.15892","doi":"https://doi.org/10.25011/cim.v34i6.15892","is_oa":true,"landing_page_url":"https://doi.org/10.25011/cim.v34i6.15892","pdf_url":"https://cimonline.ca/index.php/cim/article/download/15892/12913","source":{"id":"https://openalex.org/S133894987","display_name":"Clinical and investigative medicine","issn_l":"0147-958X","issn":["0147-958X","1488-2353"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4324392715","host_organization_name":"The Canadian Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4324392715"],"host_organization_lineage_names":["The Canadian Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical and Investigative Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1542954872.pdf","grobid_xml":"https://content.openalex.org/works/W1542954872.grobid-xml"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W203172443","https://openalex.org/W273224385","https://openalex.org/W1091300770","https://openalex.org/W1599244576","https://openalex.org/W1966562996","https://openalex.org/W1986349550","https://openalex.org/W1987651688","https://openalex.org/W1989937057","https://openalex.org/W1994914810","https://openalex.org/W2016760535","https://openalex.org/W2028259155","https://openalex.org/W2030787481","https://openalex.org/W2032639081","https://openalex.org/W2034485512","https://openalex.org/W2047434402","https://openalex.org/W2050158303","https://openalex.org/W2074914768","https://openalex.org/W2075429176","https://openalex.org/W2077689523","https://openalex.org/W2079615611","https://openalex.org/W2080920887","https://openalex.org/W2089539550","https://openalex.org/W2094892482","https://openalex.org/W2096657836","https://openalex.org/W2107812175","https://openalex.org/W2112720813","https://openalex.org/W2117883320","https://openalex.org/W2139581386","https://openalex.org/W2140503446","https://openalex.org/W2219924697","https://openalex.org/W2990123797","https://openalex.org/W3023365710","https://openalex.org/W4244648154","https://openalex.org/W4252853239"],"related_works":["https://openalex.org/W2114254893","https://openalex.org/W2460671365","https://openalex.org/W2399676726","https://openalex.org/W3197628585","https://openalex.org/W2117883320","https://openalex.org/W7135055973","https://openalex.org/W4399678604","https://openalex.org/W2884879686","https://openalex.org/W4385969224","https://openalex.org/W1540176599"],"abstract_inverted_index":{"PURPOSE:":[0],"Mean":[1],"platelet":[2,9],"volume":[3],"(MPV)":[4],"is":[5,12],"an":[6,170],"indicator":[7],"of":[8,19,47,202],"activation,":[10],"which":[11],"a":[13,224],"central":[14],"process":[15],"in":[16,44,67,84,99,138,147,155,207,227],"the":[17,45,58,139],"pathophysiology":[18],"coronary":[20],"heart":[21],"disease.":[22],"Metabolic":[23],"syndrome":[24,71,115,211,231],"(MS)":[25],"may":[26,218],"lead":[27],"to":[28,56,220],"worsened":[29],"left":[30,63,90,105,123,151,161,177,203],"ventricular":[31,64,178],"systolic":[32,65,92,107,125,153,163,179,205],"function":[33,66,93,108,126,154,164],"by":[34,40],"causing":[35],"recurrent":[36],"thrombotic":[37],"events":[38],"and":[39,62,98,116,175,232],"aggravating":[41],"systemic":[42],"inflammation":[43],"course":[46],"acute":[48],"myocardial":[49,76,120,215],"infarction.":[50,77,121,216],"The":[51],"present":[52],"study":[53],"was":[54,80,127,144],"designed":[55],"investigate":[57],"relationship":[59,172],"between":[60,173],"MPV":[61,79,134,143,174,194,217],"patients":[68,86,101,148,158,208,228],"with":[69,113,149,157,200,209,212,229],"metabolic":[70,114,210,230],"who":[72,87,102],"had":[73,88,103],"first":[74,117,213],"ST-elevation":[75,214],"METHODS:":[78],"measured":[81],"on":[82,195],"admission":[83,196],"33":[85],"preserved":[89,160],"ventricle":[91,106,124,152,162,204],"(mean":[94,109],"age,":[95,110],"56.9\u00b110.2":[96],"years)":[97,112],"48":[100],"depressed":[104,150],"57.9\u00b110.5":[111],"ST":[118,233],"elevation":[119,234],"Depressed":[122],"defined":[128],"as":[129,223],"\u226450%":[130],"ejection":[131],"fraction":[132],"value.":[133],"levels":[135],"were":[136],"compared":[137],"two":[140],"groups.":[141],"RESULTS:":[142],"significantly":[145],"higher":[146],"comparison":[156],"showing":[159],"(p=0.02).":[165],"Logistic":[166],"regression":[167],"analysis":[168],"showed":[169],"independent":[171],"deteriorated":[176],"function,":[180],"even":[181],"after":[182],"adjustment":[183],"for":[184],"potential":[185],"confounders":[186],"(1.08":[187],"(1.04-1.20),":[188],"CI:":[189],"95%,":[190],"p=0.02).":[191],"CONCLUSIONS:":[192],"Increased":[193],"can":[197],"be":[198,221],"associated":[199],"degree":[201],"depression":[206],"prove":[219],"useful":[222],"prognostic":[225],"marker":[226],"MI.":[235]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}