{"id":"https://openalex.org/W154197903","doi":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","title":"Preservation of renal function in the obese Zucker rat by antioxidant diet","display_name":"Preservation of renal function in the obese Zucker rat by antioxidant diet","publication_year":2008,"publication_date":"2008-03-01","ids":{"openalex":"https://openalex.org/W154197903","doi":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","mag":"154197903"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.22.1_supplement.944.2","doi":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012970497","display_name":"Sharon R. Inman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon Ruth Inman","raw_affiliation_strings":["Biomedical Sciences Ohio University Athens OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Ohio University Athens OH","institution_ids":["https://openalex.org/I4210106879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111330901","display_name":"EDWIN J JACKSON","orcid":"https://orcid.org/0000-0001-8824-7750","observed_orcids":["https://orcid.org/0000-0001-8824-7750"]},"institutions":[{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin Jackson","raw_affiliation_strings":["Biomedical Sciences Ohio University Athens OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Ohio University Athens OH","institution_ids":["https://openalex.org/I4210106879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076017615","display_name":"Olusayo Oshogwemoh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olusayo Oshogwemoh","raw_affiliation_strings":["Biomedical Sciences Ohio University Athens OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Ohio University Athens OH","institution_ids":["https://openalex.org/I4210106879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022509472","display_name":"Yuriy Slyvka","orcid":"https://orcid.org/0000-0002-4922-9362","observed_orcids":["https://orcid.org/0000-0002-4922-9362"]},"institutions":[{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuriy Slyvka","raw_affiliation_strings":["Biomedical Sciences Ohio University Athens OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Ohio University Athens OH","institution_ids":["https://openalex.org/I4210106879"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060735154","display_name":"Felicia V. Nowak","orcid":"https://orcid.org/0000-0001-8601-3619","observed_orcids":["https://orcid.org/0000-0001-8601-3619"]},"institutions":[{"id":"https://openalex.org/I4210106879","display_name":"Ohio University","ror":"https://ror.org/01jr3y717","country_code":"US","type":"education","lineage":["https://openalex.org/I4210106879"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Felicia V Nowak","raw_affiliation_strings":["Biomedical Sciences Ohio University Athens OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Sciences Ohio University Athens OH","institution_ids":["https://openalex.org/I4210106879"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210106879"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01921077,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"22","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antioxidant-rich-diet","display_name":"antioxidant diet","score":0.859000027179718},{"id":"https://openalex.org/keywords/renal-function","display_name":"renal function","score":0.49900001287460327},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.8339999914169312},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9750000238418579},{"id":"https://openalex.org/keywords/obese-zucker-rats","display_name":"Zucker fatty rats","score":0.6980000138282776},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.597000002861023},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.9909999966621399},{"id":"https://openalex.org/keywords/mean-arterial-pressure","display_name":"mean arterial pressure","score":0.9419999718666077},{"id":"https://openalex.org/keywords/blood-glucose","display_name":"blood glucose","score":0.9860000014305115},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.7870000004768372}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8010071516036987},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7727571725845337},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6930617094039917},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.6711835265159607},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6036044359207153},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5688995718955994},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.46144288778305054},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4551349878311157}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.22.1_supplement.944.2","doi":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.22.1_supplement.944.2","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G95837365","display_name":"Antioxidants and Development of Diabetic Nephropathy","funder_award_id":"R15DK073066","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2083067028","https://openalex.org/W2274052111","https://openalex.org/W2250443404","https://openalex.org/W2281464928","https://openalex.org/W2060006528","https://openalex.org/W137832533","https://openalex.org/W4310987817","https://openalex.org/W2599707479","https://openalex.org/W2115761632","https://openalex.org/W3032172324"],"abstract_inverted_index":{"Type":[0,27],"2":[1,28],"diabetes":[2,8,29],"accounts":[3],"for":[4],"90\u201395%":[5],"of":[6,16,26,37,41,43,51,67],"all":[7],"mellitus":[9],"and":[10,39,54,64,72,85,98,202,220,237],"is":[11],"the":[12,34,49,111,120,147,152,166],"worldwide":[13],"leading":[14],"cause":[15],"end\u2010stage":[17],"renal":[18],"disease":[19],"(ESRD).":[20],"The":[21,90,161,223],"obese":[22,56,214],"Zucker":[23,57,215],"rat":[24],"model":[25],"was":[30,76,114,133,144,185,189,225],"used":[31],"to":[32,235],"determine":[33],"gender":[35],"differences":[36],"ESRD":[38],"effect":[40,224],"administration":[42],"an":[44],"antioxidant":[45],"(AO)":[46],"diet":[47,92,113,122,149,154,168,208],"on":[48,69,95,110,119,146,151,199],"progression":[50,75],"ESRD.":[52],"Male":[53],"female":[55,102,175],"rats":[58,118,176],"(fa/fa)":[59],"were":[60],"studied":[61],"at":[62,141,193],"13":[63,173],"20":[65,106,142,194],"weeks":[66,143,195],"age":[68],"regular":[70],"(REG)":[71],"AO":[73,91,112,148,167,201,207],"diets.Disease":[74],"determined":[77],"by":[78,231],"blood":[79,99,170,221],"glucose,":[80],"mean":[81],"arterial":[82],"pressure":[83],"(MAP),":[84],"glomerular":[86],"filtration":[87],"rate":[88],"(GFR).":[89],"had":[93],"effects":[94],"GFR,":[96,218],"MAP":[97,138,188,219],"glucose":[100,171],"in":[101,105,117,136,139,172,191,197,213,228],"rats.":[103],"GFR":[104],"week":[107,174],"old":[108],"females":[109,140],"higher":[115,190],"than":[116,150,196],"REG":[121,153,203],"(0.346":[123],"\u00b1":[124],"0.098":[125],"vs":[126,156,178],"0.053\u00b1":[127],"0.031":[128],"ml/min,":[129],"p=0.028).":[130],"This":[131],"difference":[132,184],"not":[134],"observed":[135],"males.":[137],"lower":[145],"(121.5\u00b15.8":[155],"146.2\u00b11.7":[157],"mm":[158],"Hg,":[159],"p=0.02).":[160],"data":[162],"also":[163,186],"suggest":[164],"that":[165],"lowers":[169],"(371.3\u00b181.1":[177],"688.3\u00b131.9":[179],"mg/dl,":[180],"p=0.005).":[181],"A":[182],"sex":[183],"observed.":[187],"males":[192],"females,":[198],"both":[200],"diets.":[204],"Conclusion:":[205],"An":[206],"preserves":[209],"several":[210],"important":[211],"parameters":[212],"rats,":[216],"including":[217],"glucose.":[222],"more":[226],"significant":[227],"females.":[229],"Supported":[230],"NIH":[232],"R15":[233],"DK073066":[234],"SRI":[236],"FVN":[238]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}