{"id":"https://openalex.org/W153882467","doi":null,"title":"[The complement activation system in acute poststreptococcal glomerulonephritis].","display_name":"[The complement activation system in acute poststreptococcal glomerulonephritis].","publication_year":1991,"publication_date":"1991-01-01","ids":{"openalex":"https://openalex.org/W153882467","mag":"153882467","pmid":"https://pubmed.ncbi.nlm.nih.gov/1366311"},"language":"en","primary_location":{"id":"pmid:1366311","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1366311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicinski arhiv","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020108440","display_name":"Esma Cemerli\u0107-Zecevi\u0107","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Cemerli\u0107-Zecevi\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5008076358","display_name":"Momir Macanovic","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Macanovi\u0107","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00731974,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"45","issue":"1-2","first_page":"17","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.9409000277519226,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.05389999970793724,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complement-activation","display_name":"complement activation","score":0.7559999823570251},{"id":"https://openalex.org/keywords/acute-poststreptococcal-glomerulonephritis","display_name":"acute post-streptococcal glomerulonephritis","score":0.9620000123977661},{"id":"https://openalex.org/keywords/complement-c3","display_name":"complement C3","score":0.6259999871253967},{"id":"https://openalex.org/keywords/complement-c4","display_name":"complement C4","score":0.6290000081062317},{"id":"https://openalex.org/keywords/classical-complement-pathway","display_name":"classical complement pathway","score":0.7549999952316284},{"id":"https://openalex.org/keywords/alternative-complement-pathway","display_name":"alternative complement pathway","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hemolytic-complement","display_name":"hemolytic complement","score":0.7509999871253967},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.628000020980835},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.37599998712539673}],"concepts":[{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.9067561626434326},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.8086742162704468},{"id":"https://openalex.org/C189446657","wikidata":"https://www.wikidata.org/wiki/Q4736500","display_name":"Alternative complement pathway","level":4,"score":0.7642844915390015},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6048564910888672},{"id":"https://openalex.org/C2780368995","wikidata":"https://www.wikidata.org/wiki/Q605006","display_name":"Glomerulonephritis","level":3,"score":0.5592367053031921},{"id":"https://openalex.org/C171279029","wikidata":"https://www.wikidata.org/wiki/Q5128320","display_name":"Classical complement pathway","level":4,"score":0.511781632900238},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5093804597854614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.493417888879776},{"id":"https://openalex.org/C3018877678","wikidata":"https://www.wikidata.org/wiki/Q1538490","display_name":"Acute glomerulonephritis","level":4,"score":0.4835922122001648},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.2895609736442566},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2513120174407959},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19305956363677979},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07671806216239929},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.0627133846282959},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003167","descriptor_name":"Complement Activation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003176","descriptor_name":"Complement C3","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D003181","descriptor_name":"Complement C4","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005921","descriptor_name":"Glomerulonephritis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D005921","descriptor_name":"Glomerulonephritis","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013290","descriptor_name":"Streptococcal Infections","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015941","descriptor_name":"Complement Hemolytic Activity Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:1366311","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1366311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medicinski arhiv","raw_type":"English Abstract"},{"id":"mag:153882467","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1366311","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1969288113","https://openalex.org/W2025412732","https://openalex.org/W2463222135","https://openalex.org/W1538378010","https://openalex.org/W2039724104","https://openalex.org/W2424895563","https://openalex.org/W3161674963","https://openalex.org/W1968707206","https://openalex.org/W2186842798","https://openalex.org/W2766978210"],"abstract_inverted_index":{"The":[0,74],"activation":[1,20,112,148],"of":[2,10,16,18,33,36,46,57,60,70,77,99,113,140,147,161,166,168],"the":[3,11,31,44,47,61,71,78,97,100,104,111,114,120,127,138,141,144],"complement":[4,19,62,115,169],"system":[5,116],"is":[6,21],"very":[7],"important":[8],"part":[9,133],"immunologic":[12],"process.":[13],"Measuring":[14],"levels":[15,56,69],"products":[17],"a":[22,34,157],"useful":[23],"diagnostic":[24],"and":[25,64,92,164],"prognostic":[26],"procedure.":[27],"This":[28],"report":[29],"presents":[30],"results":[32,139],"follow-up":[35],"54":[37],"children":[38],"with":[39],"acute":[40],"poststreptococcal":[41],"glomerulonephritis.":[42],"At":[43],"beginning":[45,98],"disease,":[48,101],"all":[49],"patients":[50,66],"(i.":[51],"e.":[52],"100%)":[53],"had":[54,67],"decreased":[55,68],"C3":[58],"component":[59,128],"system,":[63],"72.2%":[65],"haemolytic":[72,142],"complement.":[73],"mean":[75],"value":[76],"control":[79],"measurements":[80],"increased":[81],"significantly":[82],"from":[83],"one":[84],"measurement":[85],"to":[86,108,137],"another":[87],"(with":[88],"p":[89],"<":[90],"0.01,":[91],"within":[93],"6":[94],"weeks":[95],"after":[96],"it":[102],"reached":[103],"normal":[105],"range.":[106],"According":[107,136],"our":[109],"results,":[110],"was":[117,149,156],"induced":[118],"by":[119],"classical":[121],"pathway.":[122],"We":[123,152],"cannot":[124],"explain":[125],"why":[126],"C4":[129],"did":[130],"not":[131],"take":[132],"in":[134],"it.":[135],"assay,":[143],"alternative":[145],"pathway":[146],"used":[150],"too.":[151],"found":[153],"that":[154],"there":[155],"correlation":[158],"between":[159],"improvement":[160],"clinical":[162],"features":[163],"decrease":[165],"metabolisation":[167],"components.":[170]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}