{"id":"https://openalex.org/W15377337","doi":"https://doi.org/10.1042/bj1360639","title":"Ethanol administration and the relationship of malonyl-coenzyme A concentrations to the rate of fatty acid synthesis in rat liver","display_name":"Ethanol administration and the relationship of malonyl-coenzyme A concentrations to the rate of fatty acid synthesis in rat liver","publication_year":1973,"publication_date":"1973-11-15","ids":{"openalex":"https://openalex.org/W15377337","doi":"https://doi.org/10.1042/bj1360639","mag":"15377337","pmid":"https://pubmed.ncbi.nlm.nih.gov/4149946","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1165999"},"language":"en","primary_location":{"id":"doi:10.1042/bj1360639","doi":"https://doi.org/10.1042/bj1360639","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1360639","pdf_url":"https://portlandpress.com/biochemj/article-pdf/136/3/639/780733/bj1360639.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://portlandpress.com/biochemj/article-pdf/136/3/639/780733/bj1360639.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108287835","display_name":"Robert W. Guynn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert W. Guynn","raw_affiliation_strings":["Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029632221","display_name":"Dulce Veloso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dulce Veloso","raw_affiliation_strings":["Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061578297","display_name":"R. L. Harris","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raymond L. Harris","raw_affiliation_strings":["Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034158065","display_name":"Jonathan Lawson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. W. Randolph Lawson","raw_affiliation_strings":["Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004652247","display_name":"Richard L. Veech","orcid":"https://orcid.org/0000-0003-2709-939X","observed_orcids":["https://orcid.org/0000-0003-2709-939X"]},"institutions":[{"id":"https://openalex.org/I2802104953","display_name":"St. Elizabeths Hospital","ror":"https://ror.org/022w03s59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802104953","https://openalex.org/I4210099492"]},{"id":"https://openalex.org/I4210158500","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210158500"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard L. Veech","raw_affiliation_strings":["Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section on Neurochemistry, National Institute of Mental Health, Intramural Research Program, Special Mental Health Research, Division of Neurochemistry and the National Institute of Alcohol Abuse and Alcoholism, Saint Elizabeths Hospital, Washington, D.C. 20032, U.S.A","institution_ids":["https://openalex.org/I2802104953","https://openalex.org/I4210158500"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.3367,"has_fulltext":true,"cited_by_count":37,"citation_normalized_percentile":{"value":0.73066298,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"136","issue":"3","first_page":"639","last_page":"647"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8740000128746033,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.8740000128746033,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.056299999356269836,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.04149999842047691,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ethanol","display_name":"ethanol","score":0.9750000238418579},{"id":"https://openalex.org/keywords/fatty-acid-synthesis","display_name":"fatty acid synthesis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/malonyl-coa","display_name":"malonyl-CoA","score":0.968999981880188},{"id":"https://openalex.org/keywords/fatty-acid-synthase","display_name":"fatty acid synthase","score":0.8360000252723694},{"id":"https://openalex.org/keywords/hepatic-lipid-metabolism","display_name":"hepatic lipid metabolism","score":0.6110000014305115},{"id":"https://openalex.org/keywords/starvation","display_name":"starvation","score":0.3540000021457672},{"id":"https://openalex.org/keywords/glucose","display_name":"glucose","score":0.7139999866485596},{"id":"https://openalex.org/keywords/nad-redox-state","display_name":"NAD redox state","score":0.7829999923706055},{"id":"https://openalex.org/keywords/citrate","display_name":"citrate","score":0.7620000243186951},{"id":"https://openalex.org/keywords/de-novo-lipogenesis","display_name":"de novo lipogenesis","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.6848562955856323},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.646065354347229},{"id":"https://openalex.org/C2779123261","wikidata":"https://www.wikidata.org/wiki/Q407635","display_name":"Coenzyme A","level":4,"score":0.5588160753250122},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.494646281003952},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.47231361269950867},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.4704743027687073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26999765634536743},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1179233193397522},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.1178884208202362},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000103","descriptor_name":"Acetyl-CoA Carboxylase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002951","descriptor_name":"Citrates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003065","descriptor_name":"Coenzyme A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D005947","descriptor_name":"Glucose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D005958","descriptor_name":"Glucosephosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008314","descriptor_name":"Malonates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009243","descriptor_name":"NAD","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011773","descriptor_name":"Pyruvates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013217","descriptor_name":"Starvation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014316","descriptor_name":"Tritium","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064429","descriptor_name":"Fatty Acid Synthases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1042/bj1360639","doi":"https://doi.org/10.1042/bj1360639","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1360639","pdf_url":"https://portlandpress.com/biochemj/article-pdf/136/3/639/780733/bj1360639.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1165999","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1165999","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"},{"id":"pmid:4149946","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/4149946","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1042/bj1360639","doi":"https://doi.org/10.1042/bj1360639","is_oa":true,"landing_page_url":"https://doi.org/10.1042/bj1360639","pdf_url":"https://portlandpress.com/biochemj/article-pdf/136/3/639/780733/bj1360639.pdf","source":{"id":"https://openalex.org/S4210234214","display_name":"Biochemical Journal","issn_l":"0306-3283","issn":["0306-3283"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W15377337.pdf","grobid_xml":"https://content.openalex.org/works/W15377337.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W127599359","https://openalex.org/W152486275","https://openalex.org/W178306213","https://openalex.org/W1590222530","https://openalex.org/W1642400962","https://openalex.org/W1676193473","https://openalex.org/W1794860149","https://openalex.org/W1828392481","https://openalex.org/W1860024159","https://openalex.org/W1970718349","https://openalex.org/W1979524412","https://openalex.org/W1981196498","https://openalex.org/W1990268190","https://openalex.org/W1993007387","https://openalex.org/W1999021662","https://openalex.org/W2000908867","https://openalex.org/W2006708365","https://openalex.org/W2007848694","https://openalex.org/W2013152538","https://openalex.org/W2015953760","https://openalex.org/W2022143718","https://openalex.org/W2023071988","https://openalex.org/W2025322100","https://openalex.org/W2035135461","https://openalex.org/W2041367511","https://openalex.org/W2046470009","https://openalex.org/W2048909893","https://openalex.org/W2054662884","https://openalex.org/W2058272150","https://openalex.org/W2060824250","https://openalex.org/W2061172376","https://openalex.org/W2062410652","https://openalex.org/W2081703952","https://openalex.org/W2106363351","https://openalex.org/W2143758494","https://openalex.org/W2157286372","https://openalex.org/W2165953224","https://openalex.org/W2343265513","https://openalex.org/W2400497255","https://openalex.org/W2410584582","https://openalex.org/W2415749798","https://openalex.org/W2438246644"],"related_works":["https://openalex.org/W2182042434","https://openalex.org/W2066439973","https://openalex.org/W2156053762","https://openalex.org/W152486275","https://openalex.org/W2033584382","https://openalex.org/W1806138564","https://openalex.org/W175497021","https://openalex.org/W2015578761","https://openalex.org/W2443518585","https://openalex.org/W2059391872"],"abstract_inverted_index":{"1.":[0],"The":[1,154],"effect":[2,65,186],"of":[3,42,44,51,54,61,69,80,84,92,99,135,160,172,178,190,200,210,216,227,230,250,262,269,282,288],"ethanol":[4,56,85,121,181,308],"on":[5,66,187],"liver":[6,179,217,303],"fatty":[7,191,218,251,263,289],"acid":[8,192,219,252,264],"synthesis":[9,193,253,287],"was":[10,35,122,204],"studied":[11],"in":[12,14,89,117,156,170,194,213,222,254,300],"vivo":[13,255],"24h-starved":[15,77],"and":[16,25,140,176,233,266],";meal-fed'":[17],"rats":[18],"(i.e.":[19],"fed":[20,32],"for":[21],"3h":[22,107],"per":[23,47,102,138],"day":[24],"not":[26],"ad":[27],"libitum).":[28],"2.":[29],"In":[30,75],"the":[31,67,76,81,90,128,141,157,168,188,198,201,211,214,228,234,248,260,267,280,283,286,301],"animal":[33],"(3)H(2)O":[34,70,93,129,231],"incorporated":[36],"into":[37,72],"fat":[38],"at":[39,151],"a":[40,240],"rate":[41,68,91,189,229,249],"0.46mumol":[43],"C(2)":[45,100,136],"units/min":[46,101,137],"g":[48,103,139],"wet":[49,149],"wt.":[50,105,150],"liver.":[52],"Administration":[53],"either":[55],"(3.2g/kg)":[57],"or":[58,164,167],"equicaloric":[59,119],"amounts":[60,118],"glucose":[62,174],"had":[63,183],"no":[64,184,205],"incorporation":[71,94,130,232],"lipid.":[73],"3.":[74],"animal,":[78],"administration":[79,182],"same":[82],"dose":[83],"produced":[86],"an":[87,297],"increase":[88],"from":[95,111,131,144],"0.06":[96,132],"to":[97,113,120,133,146,295],"0.12mumol":[98],"fresh":[104],"after":[106,180],"whereas":[108],"[malonyl-CoA]":[109],"increased":[110,302],"0.006":[112,145],"0.009mumol/g.":[114],"Glucose":[115],"given":[116],"significantly":[123],"more":[124],"lipogenic,":[125],"increasing":[126],"both":[127],"0.20mumol":[134],"malonyl-CoA":[142,237],"content":[143,171,305],"0.013":[147],"mumol/g":[148],"3h.":[152],"4.":[153],"decrease":[155],"redox":[158],"state":[159],"free":[161,270],"cytoplasm":[162],"NAD":[163],"NADP":[165],"couples":[166],"changes":[169],"citrate,":[173],"6-phosphate":[175],"pyruvate":[177],"measurable":[185],"vivo.":[195],"5.":[196],"Under":[197],"conditions":[199,281],"experiments":[202],"there":[203],"significant":[206],"difference,":[207],"among":[208],"any":[209],"groups,":[212],"activity":[215],"synthetase":[220,265],"measured":[221],"vitro.":[223],"A":[224],"double-reciprocal":[225],"plot":[226],"total":[235],"tissue":[236],"concentrations":[238],"showed":[239],"striking":[241],"relationship.":[242],"It":[243,273],"has":[244,274],"been":[245,276],"concluded":[246,277],"that":[247,278],"is":[256,293],"determined":[257],"principally":[258],"by":[259],"V(max.)":[261],"concentration":[268],"malonyl-CoA.":[271],"6.":[272],"also":[275],"under":[279],"present":[284],"study,":[285],"acids":[290],"de":[291],"novo":[292],"unlikely":[294],"be":[296],"important":[298],"factor":[299],"lipid":[304],"associated":[306],"with":[307],"administration.":[309]},"counts_by_year":[{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}