{"id":"https://openalex.org/W153425946","doi":null,"title":"Clinical and pathological response to induction chemotherapy used as a prognostic factor in inflammatory breast cancer. Single institution experience.","display_name":"Clinical and pathological response to induction chemotherapy used as a prognostic factor in inflammatory breast cancer. Single institution experience.","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W153425946","mag":"153425946","pmid":"https://pubmed.ncbi.nlm.nih.gov/22517688"},"language":"en","primary_location":{"id":"pmid:22517688","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22517688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of B.U.ON. : official journal of the Balkan Union of Oncology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048617492","display_name":"Daniela Kolarevi\u0107","orcid":"https://orcid.org/0000-0003-3450-6344","observed_orcids":["https://orcid.org/0000-0003-3450-6344"]},"institutions":[{"id":"https://openalex.org/I4210110112","display_name":"Institut za onkologiju i radiologiju Srbije","ror":"https://ror.org/01ykx8d32","country_code":"RS","type":"healthcare","lineage":["https://openalex.org/I4210110112"]}],"countries":["RS"],"is_corresponding":false,"raw_author_name":"D Kolarevic","raw_affiliation_strings":["Clinic for Medical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia. daniela_kolarevic@yahoo.co.uk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinic for Medical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia. daniela_kolarevic@yahoo.co.uk","institution_ids":["https://openalex.org/I4210110112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012594351","display_name":"Zorica I. Tomasevic","orcid":"https://orcid.org/0000-0003-0171-6855","observed_orcids":["https://orcid.org/0000-0003-0171-6855"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Z Tomasevic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091501602","display_name":"Radan R D\u017eodi\u0107","orcid":"https://orcid.org/0000-0002-3041-7339","observed_orcids":["https://orcid.org/0000-0002-3041-7339"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Dzodic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036110395","display_name":"Du\u0161ica Gavrilovi\u0107","orcid":"https://orcid.org/0000-0002-2368-683X","observed_orcids":["https://orcid.org/0000-0002-2368-683X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Gavrilovic","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5079076073","display_name":"Milan \u017degarac","orcid":"https://orcid.org/0000-0002-3917-541X","observed_orcids":["https://orcid.org/0000-0002-3917-541X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Zegarac","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1016,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.47397633,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"17","issue":"1","first_page":"21","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.7675999999046326,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.7675999999046326,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11134","display_name":"Breast Lesions and Carcinomas","score":0.2240999937057495,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/inflammatory-breast-cancer","display_name":"inflammatory breast cancer","score":0.9779999852180481},{"id":"https://openalex.org/keywords/induction-chemotherapy","display_name":"induction chemotherapy","score":0.9929999709129333},{"id":"https://openalex.org/keywords/anthracycline-based-chemotherapy","display_name":"anthracycline chemotherapy","score":0.9150000214576721},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.9309999942779541},{"id":"https://openalex.org/keywords/clinical-response","display_name":"clinical response","score":0.8500000238418579},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8479999899864197},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.7509999871253967},{"id":"https://openalex.org/keywords/bone-metastases","display_name":"bone metastasis","score":0.75},{"id":"https://openalex.org/keywords/central-nervous-system-metastases","display_name":"central nervous system metastasis","score":0.9399999976158142},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.6480000019073486},{"id":"https://openalex.org/keywords/stage-iiib-breast-cancer","display_name":"stage IIIB breast cancer","score":0.9100000262260437}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8786085844039917},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.7591108083724976},{"id":"https://openalex.org/C2780839634","wikidata":"https://www.wikidata.org/wiki/Q5922406","display_name":"Inflammatory breast cancer","level":4,"score":0.7334615588188171},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6377918720245361},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6031630635261536},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5802788734436035},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5580348968505859},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.5450896620750427},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.5265077948570251},{"id":"https://openalex.org/C2776611710","wikidata":"https://www.wikidata.org/wiki/Q16888295","display_name":"Induction chemotherapy","level":3,"score":0.5124574303627014},{"id":"https://openalex.org/C2776802502","wikidata":"https://www.wikidata.org/wiki/Q417589","display_name":"Anthracycline","level":4,"score":0.48425790667533875},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4662676453590393},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.43510743975639343},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41946935653686523},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058922","descriptor_name":"Inflammatory Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D058922","descriptor_name":"Inflammatory Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D058922","descriptor_name":"Inflammatory Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D060828","descriptor_name":"Induction Chemotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:22517688","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22517688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of B.U.ON. : official journal of the Balkan Union of Oncology","raw_type":"Journal Article"},{"id":"mag:153425946","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22517688","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1501745646","https://openalex.org/W1935743463","https://openalex.org/W1971753589","https://openalex.org/W1986266651","https://openalex.org/W1987326983","https://openalex.org/W1998309234","https://openalex.org/W2008539103","https://openalex.org/W2013007711","https://openalex.org/W2017605431","https://openalex.org/W2025959372","https://openalex.org/W2044451636","https://openalex.org/W2049793977","https://openalex.org/W2059455453","https://openalex.org/W2063348941","https://openalex.org/W2063779636","https://openalex.org/W2072543229","https://openalex.org/W2078915424","https://openalex.org/W2084465587","https://openalex.org/W2089637126","https://openalex.org/W2091947586","https://openalex.org/W2096849721","https://openalex.org/W2113137803","https://openalex.org/W2113334910","https://openalex.org/W2133003338","https://openalex.org/W2133764807","https://openalex.org/W2156894263","https://openalex.org/W2161791469","https://openalex.org/W2170869228","https://openalex.org/W2231000545","https://openalex.org/W2232616986","https://openalex.org/W2318126748","https://openalex.org/W4294413353","https://openalex.org/W4323874309"],"related_works":["https://openalex.org/W2909085864","https://openalex.org/W4401699946","https://openalex.org/W4390227762","https://openalex.org/W2560213171","https://openalex.org/W1966662356","https://openalex.org/W1986266651","https://openalex.org/W4322769614","https://openalex.org/W2148468871","https://openalex.org/W7162508804","https://openalex.org/W2148252918"],"abstract_inverted_index":{"PURPOSE:":[0],"To":[1],"evaluate":[2,16],"clinical":[3,21,82],"and":[4,22,29,53,61,92,113,149,169,181,263,265],"pathological":[5,23,99,105,143],"characteristics":[6],"of":[7,19,35,41,63,70,79,138,194,217,257],"patients":[8,44,72,120,153,164,219,241],"with":[9,45,255],"inflammatory":[10],"breast":[11],"carcinoma":[12],"(IBC).":[13],"Also,":[14,98],"to":[15,25,101,207,231,245,247],"the":[17,33,57,71,81,139,142,177,182,215,218],"importance":[18],"achieved":[20],"responses":[24],"induction":[26],"chemotherapy":[27],"(iCT)":[28],"their":[30],"role":[31],"in":[32,119,136,152,179,184,192,221,261],"prognosis":[34],"IBC.":[36],"METHODS:":[37],"The":[38],"medical":[39],"records":[40],"81":[42],"female":[43],"stage":[46],"IIIB":[47],"IBC,":[48],"diagnosed":[49],"between":[50],"January":[51],"2008":[52],"December":[54],"2010":[55],"at":[56],"Institute":[58],"for":[59,253],"Oncology":[60],"Radiology":[62],"Serbia":[64],"(IORS)":[65],"were":[66,129,176],"evaluated.":[67],"Almost":[68],"all":[69],"received":[73],"anthracycline-based":[74],"iCT.":[75],"After":[76],"3-4":[77],"cycles":[78],"iCT,":[80],"response":[83,100,144,230],"(defined":[84,103],"as":[85,104,236],"complete":[86,106,109,147],"response/CR,":[87],"partial":[88,111],"response/PR,":[89],"stable":[90],"disease/SD":[91],"disease":[93],"progression/":[94],"PD)":[95],"was":[96,117,134,158],"assessed.":[97],"iCT":[102,232,248],"response/pCR,":[107],"near":[108],"response/pNCR,":[110],"response/pPR":[112],"no":[114,197],"change/":[115],"pNC)":[116],"estimated":[118],"who":[121,154,242],"had":[122,155,203],"undergone":[123,156],"surgery.":[124],"All":[125],"first":[126],"metastatic":[127,174],"sites":[128,175],"recorded.":[130],"RESULTS:":[131],"Clinical":[132],"CR/PR":[133],"observed":[135],"61.8%":[137],"patients,":[140],"while":[141,196],"(pCR,":[145],"pNCR/near":[146],"response,":[148],"pPR)":[150],"rate":[151],"surgery":[157],"70%.":[159],"During":[160],"follow-up":[161],"22":[162],"(27.2%)":[163],"developed":[165,191,199],"PD":[166,254],"(8":[167],"responders":[168],"14":[170],"non-responders).":[171],"Most":[172],"common":[173],"skeleton":[178],"non-responders":[180,195],"liver":[183],"responders.":[185],"Central":[186],"nervous":[187],"system":[188],"(CNS)":[189],"metastases":[190],"24%":[193],"responder":[198],"such":[200],"metastases.":[201],"Non-responders":[202],"shorter":[204,266],"OS":[205],"compared":[206],"responders,":[208],"but":[209],"without":[210],"statistical":[211],"significance.":[212],"CONCLUSION:":[213],"Although":[214],"number":[216],"analysed":[220],"this":[222],"study":[223],"is":[224],"relatively":[225],"small,":[226],"we":[227],"believe":[228],"that":[229],"could":[233],"be":[234],"used":[235],"a":[237,250],"prognostic":[238],"marker,":[239],"since":[240],"initially":[243],"failed":[244],"respond":[246],"showed":[249],"higher":[251],"risk":[252],"development":[256],"distant":[258],"metastases,":[259],"primarily":[260],"bones":[262],"CNS,":[264],"survival.":[267]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}