{"id":"https://openalex.org/W1531758735","doi":"https://doi.org/10.1107/97809553602060000689","title":"Ab initio phasing","display_name":"Ab initio phasing","publication_year":2006,"publication_date":"2006-09-11","ids":{"openalex":"https://openalex.org/W1531758735","doi":"https://doi.org/10.1107/97809553602060000689","mag":"1531758735"},"language":"en","primary_location":{"id":"doi:10.1107/97809553602060000689","doi":"https://doi.org/10.1107/97809553602060000689","is_oa":false,"landing_page_url":"https://doi.org/10.1107/97809553602060000689","pdf_url":null,"source":{"id":"https://openalex.org/S2764888795","display_name":"International Tables for Crystallography","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Tables for Crystallography","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2500982282","display_name":"International Tables for Crystallography"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042885999","display_name":"George M. Sheldrick","orcid":"https://orcid.org/0000-0001-6956-4822","observed_orcids":["https://orcid.org/0000-0001-6956-4822"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"G. M. Sheldrick","raw_affiliation_strings":["Institut f\u00fcr Anorganisch Chemie, Universit\u00e4t G\u00f6ttingen, Tammannstrasse 4, D-37077 G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Anorganisch Chemie, Universit\u00e4t G\u00f6ttingen, Tammannstrasse 4, D-37077 G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084474101","display_name":"Herbert A. Hauptman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. A. Hauptman","raw_affiliation_strings":["Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108739443","display_name":"Charles M. Weeks","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. M. Weeks","raw_affiliation_strings":["Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109286228","display_name":"Russ Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1287610024","display_name":"Hauptman-Woodward Medical Research Institute","ror":"https://ror.org/02e1cpg76","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1287610024"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Miller","raw_affiliation_strings":["Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hauptman\u2010Woodward Medical Research Institute, Inc., 73 High Street, Buffalo, NY 14203\u20101196, USA","institution_ids":["https://openalex.org/I1287610024"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078532647","display_name":"Isabel Us\u00f3n","orcid":"https://orcid.org/0000-0003-2504-1696","observed_orcids":["https://orcid.org/0000-0003-2504-1696"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I. Us\u00f3n","raw_affiliation_strings":["Lehrstuhl f\u00fcr Strukturchemie, Universit\u00e4t G\u00f6ttingen, Tammannstrasse 4, D-37077 G\u00f6ttingen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Strukturchemie, Universit\u00e4t G\u00f6ttingen, Tammannstrasse 4, D-37077 G\u00f6ttingen, Germany","institution_ids":["https://openalex.org/I74656192"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.2409,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.98550725,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"333","last_page":"345"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.9535999894142151,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12613","display_name":"X-ray Diffraction in Crystallography","score":0.023800000548362732,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10464","display_name":"Crystal structures of chemical compounds","score":0.011500000022351742,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ab-initio-phasing","display_name":"ab initio phasing","score":0.9850000143051147},{"id":"https://openalex.org/keywords/direct-method","display_name":"direct method","score":0.8529999852180481},{"id":"https://openalex.org/keywords/phase-refinement","display_name":"phase refinement","score":0.8669999837875366},{"id":"https://openalex.org/keywords/peak-picking","display_name":"peak picking","score":0.949999988079071},{"id":"https://openalex.org/keywords/density-modification","display_name":"density modification","score":0.9729999899864197},{"id":"https://openalex.org/keywords/charge-flipping","display_name":"charge flipping","score":0.9739999771118164},{"id":"https://openalex.org/keywords/patterson-function","display_name":"Patterson function","score":0.5759999752044678},{"id":"https://openalex.org/keywords/space-group-p1","display_name":"triclinic P1 space group","score":0.8629999756813049},{"id":"https://openalex.org/keywords/crystal-structure-refinement","display_name":"crystal structure refinement","score":0.5820000171661377},{"id":"https://openalex.org/keywords/macromolecules","display_name":"macromolecules","score":0.7170000076293945}],"concepts":[{"id":"https://openalex.org/C2781442258","wikidata":"https://www.wikidata.org/wiki/Q46310","display_name":"Ab initio","level":2,"score":0.6520311236381531},{"id":"https://openalex.org/C135393689","wikidata":"https://www.wikidata.org/wiki/Q1551588","display_name":"Phaser","level":2,"score":0.4137084484100342},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2972111105918884},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.09959018230438232},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0719459056854248}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1107/97809553602060000689","doi":"https://doi.org/10.1107/97809553602060000689","is_oa":false,"landing_page_url":"https://doi.org/10.1107/97809553602060000689","pdf_url":null,"source":{"id":"https://openalex.org/S2764888795","display_name":"International Tables for Crystallography","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Tables for Crystallography","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2052682414","https://openalex.org/W7099246905","https://openalex.org/W2151435744","https://openalex.org/W4246692263","https://openalex.org/W2087018955","https://openalex.org/W7128396788","https://openalex.org/W1999073162","https://openalex.org/W1576529466","https://openalex.org/W1603688087","https://openalex.org/W1700519873"],"abstract_inverted_index":{"The":[0],"background":[1],"and":[2,50,77,87],"use":[3,58],"of":[4,13,21,24,59,72,81],"dual-space":[5],"direct":[6],"methods":[7],"for":[8],"the":[9,19,57,70],"ab":[10],"initio":[11],"phasing":[12,20],"small":[14],"macromolecules":[15],"as":[16,18],"well":[17],"heavy-atom":[22],"substructures":[23],"larger":[25],"biological":[26],"structures":[27],"are":[28,56,98],"described.":[29,101],"Basic":[30],"concepts":[31,97],"include":[32],"normalized":[33],"structure":[34],"factors,":[35],"multisolution":[36],"procedures,":[37],"random":[38],"trial":[39],"structures,":[40],"phase-refinement":[41],"formulas,":[42],"peak-picking":[43],"techniques,":[44],"density":[45],"modification":[46],"including":[47],"charge":[48],"flipping,":[49],"recognizing":[51],"solutions.":[52],"Other":[53],"topics":[54],"discussed":[55],"Patterson":[60],"information":[61],"to":[62],"get":[63],"better":[64],"starting":[65],"phases,":[66],"avoiding":[67],"false":[68],"minima,":[69],"effects":[71],"data":[73,75],"resolution,":[74],"quality":[76],"completeness,":[78],"special":[79],"features":[80],"space":[82],"group":[83],"P1,":[84],"refinement":[85],"strategies,":[86],"future":[88],"possibilities.":[89],"Several":[90],"independent":[91],"computer":[92],"programs":[93],"that":[94],"implement":[95],"these":[96],"then":[99],"briefly":[100]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2016-06-24T00:00:00"}